Macros automate repetitive tasks in Microsoft Access by recording and playing back a series of commands. They can be run from buttons or menus. Macros are created using either built-in or user-written commands in the VBA programming language. Common uses of macros include data entry validation, opening forms, filtering records, printing, and navigating between records. Macros contain actions applied to database objects that are triggered by events like button clicks. They allow automation of tasks like form validation, data insertion, loading, updating, and deletion.