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UNIT 3
HAEMATOLOGICAL
DISEASES
IRON DEFICIENCY
AN EM IA
DEFINATION
• Anemia usually refers to a condition in which
your blood has a lower than normal number of
red blood cells.
• Iron deficiency anemia is a condition in which
the body lack enough red blood cell to
transport oxygen-rich blood to body tissues
• Occurs due to reduced production of rbc or
increased loss of rbc
ETIOLOGY
• Iron-deficiency anemia is usually due to :
 blood loss
 poor diet
an inability to absorb enough iron from
food
• Blood Loss
 Blood lost causes iron depletion
In women, long or heavy menstrual
periods or bleeding fibroids in the
uterus.
Childbirth
Internal bleeding
• Poor Diet
Low iron intake.
During some stages of life, such as
pregnancy and childhood.
• Inability To Absorb Enough Iron
Even if you have enough iron in your
diet, your body may not be able to absorb
it. This can happen if you have intestinal
surgery or a disease of the intestine.
Prescription medicines that reduce acid
in the stomach also can interfere with
iron absorption.
SIGN AND SYMPTOMS
• Iron-deficiency anemia can cause:
brittle nails
cracks in the sides of the mouth
 Extreme fatigue (tiredness)
chest pain
• Pale skin
• Dizziness or lightheadedness
• Fast heart rate
• Headache
an enlarged spleen
Cold hands and feet
frequent infections.
Irritability
shortness of breath
swelling or soreness of the tongue
• Some signs and symptoms of iron-deficiency
anemia are related to the condition's causes.
 A sign of intestinal bleeding is bright red
blood in the stools or black, tarry-looking
stools.
 Very heavy menstrual bleeding, long periods, or
other vaginal bleeding may suggest that a woman
is at risk for iron-deficiency anemia.
• Severe iron-deficiency anemia can lead to:
problems with growth and development in
children
angina (chest pain)
leg pains (intermittent claudication)
PATHOPHYSILOGY
FACTORS LIKE
PREDISPOSING
SEX( MENSTRAL CYCLE),
GENETICS
PRECIPITATING
INADEQUATE IRON INTAKE, FAULTY
DIET,
BLOOD LOSS ,PREGNANCY
DECREASED INTAKE OF IRON RICH FOODS WITH BLOOD LOSS
IRON IN THE BODY IS USED UP
DECREASED IRON RESERVES NEEDED FOR HB PRODUCTION
DECREASED RBC PRODUCTION DUE TO LACK OF HB
DECREASED OXYGEN AND HB
COMPLICATION
Effects of Anemia in Pregnant Women: Pregnant women with significant anemia
may have an increased risk for poor pregnancy outcomes,particularly if they are
anemic in the first trimester.
Complications from Anemia in Children and Adolescents: In children, severe
anemia can impair growth and motor and mental development. Children
mayexhibit a shortened attention span and decreased alertness. Children with
severe iron-deficiencyanemia may also have an increased risk for stroke.
 Effects of Anemia in the Elderly:Anemia is common in older people and can
have significantly more severe complications thananemia in younger adults.
Effects of anemia in the elderly include decreased strength and increasedrisk for
falls. Anemia may have adverse effects on the heart and increase the severity of
cardiacconditions, including reducing survival rates from heart failure and heart
attacks.
UNIT 3

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Unit 3: Iron deficiency anemia

  • 3. DEFINATION • Anemia usually refers to a condition in which your blood has a lower than normal number of red blood cells. • Iron deficiency anemia is a condition in which the body lack enough red blood cell to transport oxygen-rich blood to body tissues • Occurs due to reduced production of rbc or increased loss of rbc
  • 4.
  • 5. ETIOLOGY • Iron-deficiency anemia is usually due to :  blood loss  poor diet an inability to absorb enough iron from food
  • 6. • Blood Loss  Blood lost causes iron depletion In women, long or heavy menstrual periods or bleeding fibroids in the uterus. Childbirth Internal bleeding • Poor Diet Low iron intake. During some stages of life, such as pregnancy and childhood.
  • 7. • Inability To Absorb Enough Iron Even if you have enough iron in your diet, your body may not be able to absorb it. This can happen if you have intestinal surgery or a disease of the intestine. Prescription medicines that reduce acid in the stomach also can interfere with iron absorption.
  • 8. SIGN AND SYMPTOMS • Iron-deficiency anemia can cause: brittle nails cracks in the sides of the mouth
  • 9.  Extreme fatigue (tiredness) chest pain
  • 10. • Pale skin • Dizziness or lightheadedness
  • 11. • Fast heart rate • Headache
  • 12. an enlarged spleen Cold hands and feet frequent infections. Irritability shortness of breath swelling or soreness of the tongue
  • 13. • Some signs and symptoms of iron-deficiency anemia are related to the condition's causes.  A sign of intestinal bleeding is bright red blood in the stools or black, tarry-looking stools.  Very heavy menstrual bleeding, long periods, or other vaginal bleeding may suggest that a woman is at risk for iron-deficiency anemia.
  • 14. • Severe iron-deficiency anemia can lead to: problems with growth and development in children angina (chest pain) leg pains (intermittent claudication)
  • 15. PATHOPHYSILOGY FACTORS LIKE PREDISPOSING SEX( MENSTRAL CYCLE), GENETICS PRECIPITATING INADEQUATE IRON INTAKE, FAULTY DIET, BLOOD LOSS ,PREGNANCY DECREASED INTAKE OF IRON RICH FOODS WITH BLOOD LOSS IRON IN THE BODY IS USED UP DECREASED IRON RESERVES NEEDED FOR HB PRODUCTION DECREASED RBC PRODUCTION DUE TO LACK OF HB DECREASED OXYGEN AND HB
  • 16. COMPLICATION Effects of Anemia in Pregnant Women: Pregnant women with significant anemia may have an increased risk for poor pregnancy outcomes,particularly if they are anemic in the first trimester. Complications from Anemia in Children and Adolescents: In children, severe anemia can impair growth and motor and mental development. Children mayexhibit a shortened attention span and decreased alertness. Children with severe iron-deficiencyanemia may also have an increased risk for stroke.  Effects of Anemia in the Elderly:Anemia is common in older people and can have significantly more severe complications thananemia in younger adults. Effects of anemia in the elderly include decreased strength and increasedrisk for falls. Anemia may have adverse effects on the heart and increase the severity of cardiacconditions, including reducing survival rates from heart failure and heart attacks.