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Unilateral Hyperlucent
Hemithorax
Hisham AlKhatib, M.D.
Consultant Radiologist
•‫اله‬ ‫وعلى‬ ‫هللا‬ ‫رسول‬ ‫على‬ ‫والسالم‬ ‫والصالة‬ ‫هلل‬ ‫الحمد‬
‫اجمعين‬ ‫م‬ّ‫ل‬‫وس‬ ‫وصحبه‬
•، ‫علما‬ ‫وزدني‬ ‫ينفعني‬ ‫بما‬ ‫وعلمني‬ ‫علمتني‬ ‫بما‬ ‫انفعني‬ ‫اللهم‬
‫الحكيم‬ ‫العليم‬ ‫انك‬
• Praise be to Allah and prayers be upon the
Messenger of Allah and his family and
companions.
• Oh God, give me the benefit of what you
have taught me and teach me what benefits
me.
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
• Check for central airway obstruction
– Endobronchial tumors, extrinsic compression,
foreign bodies
• Check lung parenchyma for focal air-trapping
– Exhalation CT helpful to increase confidence
• Check chest wall for evidence of prior surgery
or deformities
DIFFERENTIAL DIAGNOSIS
Common Causes
• Pneumothorax
• Mastectomy
• Prior Surgery
• Bronchial Obstruction
Helpful Clues for Common
Diagnoses
Pneumothorax
• Look for “deep sulcus” sign on supine radiographs
Mastectomy
• Breast asymmetry; surgical clips in axilla
Prior Surgery
– Single lung transplant
– Ipsilateral lobectomy
Bronchial Obstruction
– Hyperlucency from air-trapping, ball-valve effect
– Lobar collapse and hyperinflation of other lobes
– Foreign body in children
– Endobronchial tumors in adults
• Primary malignancy > endobronchial metastases
• Carcinoids commonly have central, chunky
calcifications
Less Common Causes
• Swyer-James Syndrome
• Bronchial Atresia
• Congenital Lobar Emphysema
Helpful Clues for Less Common
Diagnoses
Swyer-James Syndrome
– Unilateral postinfectious constrictive bronchiolitis
– Decreased vascular markings; air-trapping on
exhalation
– CT: Bronchiectasis often present; more extensive
air-trapping than on radiograph
Bronchial Atresia
– Collateral ventilation; air-trapping on expiratory
imaging
– Mucocele common in airway distal to obliteration
– Left upper lobe > right middle lobe > lower lobes
Congenital Lobar Emphysema
– Focal overinflation and air-trapping in
disorganized parenchyma
– Left upper lobe > right middle lobe > right lower
lobe
THANK YOU
Helpful Clues for Rare Diagnoses

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Unilateral hyperlucent hemithorax