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Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
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PPM’s (Pig Production and Marketing, Uganda) involvement in capacity development of pig value chain actors and scaling out of interventions
1. PPM’s involvement in capacity development of pig value chain actors and
scaling out of interventions
Christopher Mulindwa
Pig Production and Marketing, Uganda
Uganda Livestock Sector Consultative Meeting, Kampala, 14 March 2017
2. Pig Production and Marketing Uganda Limited is a
livestock company specializing in trade of pigs & their
products.
Long term objective
To modernize, promote and develop pig production in Uganda
through providing secure and sustainable markets, advisory
services and necessary inputs to make the sector a reliable
source of income for pig farmers in Uganda.
Key products & services include;
1. Pork (Whole Pork, Premium Pork & Mobile Pork Joint)
2. Breeding stock (Piglets, Gilts, Boars & Pregnant sows)
3. Consultancy (Training & Training material)
3. Background
• PPM/ILRI collaboration started in 2012, the same
year PPM was formally registered though was in
operation informally since 2010
• PPM/ILRI partnership was formalized on
15th/07/2015 after signing a Memorandum of
Understanding.
4. 1. To create easy access to developed training
material
2. To collaborate in execution of pig farmer training
3. To easy trade with farmers benefiting from ILRI
pig projects.
4. To facilitate linkages with other ILRI partners
5. To support research on the pig value chain
5. Access to training material
• PPM has used the 6 modules developed by ILRI to
design both short & long training packages for pig
farmers.
• 5 long training programs have been conducted
benefiting 150 pig farmers from Lira, Fortportal and
Wakiso districts in 2016.
• Also, at-least 316 pig farmers coming from different
districts benefited from the short training packages in
2016
• The trainees in turn become suppliers of slaughter
stock, buyers of breeding stock and other products
offered by the company.
• PPM also directly generate revenue from these training
programs.
6. The future of PPM training
• PPM is in the process of registration with the
Directorate of Industrial Training (DIT) in Uganda
to have its trainees assessed and awarded nationally
recognized certificates.
• This will ease access to competent pig farm laborers
and will increase employment opportunities
especially for youths in this country.
7. Other benefits
• Area of trade increased, we are directly linked to pig
farmers and live pig traders in Kamuli, Masaka and
Mukono districts.
• Processing of animal movement documents is easy due
to connections with both SVOs and DVOs made during
the project.
• New business opportunities with ILRI partners e.g CIP
• Business planning based on research findings and
recommendations
• Built my own capacity in presentations, engaging with
other partners
• Visibility of PPM nationally and internationally
• Linkages with other organization
• ILRI scientists have spared some of their time to present
during PPM trainings
8. The Pork Expo 2017
DATE: 24TH AND 25TH JUNE 2017
VENUE: Mandela National Stadium – Nambole
ENTRACE: Free
OTHERS:
1. Coupons for pork UGX 30.000 (Eat until you drop)
2. Training on pig farming UGX 30.000 (Both days)