A 40-year-old woman presented with a 3-week history of cough, fever, weight loss, and night sweats. Physical examination revealed decreased breath sounds and rales in the lungs. Chest x-ray showed dense opacities in the right middle and lower lobes, consistent with pulmonary tuberculosis. The patient was diagnosed with pulmonary TB based on clinical presentation, chest x-ray findings, and positive PCR test for M. tuberculosis. She was started on a standard 4-drug antituberculosis treatment regimen for 6-12 months to treat her active pulmonary TB infection.