Hypoxic ischemic encephalopathy with a focus on recent advancesVarun Mamgain
This document discusses hypoxic ischemic encephalopathy (HIE), focusing on recent advances. It provides data on the scope of the problem, defining key terms like HIE, perinatal asphyxia, and neonatal encephalopathy. It discusses the etiology and risk factors for HIE, as well as the pathophysiology involving disrupted cerebral blood flow, energy metabolism, excitotoxicity, oxidative stress, inflammation, and apoptosis. Indian data on HIE is presented based on Apgar scores and neurological manifestations.
This document discusses thyroid disorders in children from birth to adolescence. It begins with an introduction on the anatomy and physiology of the thyroid gland and thyroid hormone biosynthesis. It then covers congenital hypothyroidism including screening, causes, clinical presentations, investigations and treatment. Transient congenital hypothyroidism and acquired hypothyroidism are also discussed. The document concludes with sections on thyrotoxicosis including investigations and treatment of thyrotoxicosis in children.
This document outlines immunology and immunity to infection. It discusses the immune system's role in fighting infection, including humoral immunity from B cells and cellular immunity from T cells. It also addresses intracellular and extracellular pathogens. The document then focuses on primary and secondary immunodeficiency, describing the types of primary immunodeficiencies including B cell, T cell, phagocytic, and complement defects. It provides guidance on clinical evaluation and diagnostic approach for patients with suspected immunodeficiency.
Congenital Adr Hyperplasia (CAH) can appear at any age from birth to puberty where it can lead to ambiguous genitalia. It is due to absolute or relative deficiency of 17 Hydroxylase or 21 Hydroxylase enzyme.
Edwards syndrome, also known as Trisomy 18, is a genetic disorder caused by the presence of an extra 18th chromosome. It results in physical abnormalities and intellectual disabilities. Individuals with Edwards syndrome often have heart defects, respiratory issues, and feeding difficulties. Prognosis is generally poor, with 50% surviving the first week and only 5-10% living beyond one year. Treatment focuses on management of symptoms and organ dysfunction. The condition is not inherited but rather caused by a random chromosomal error and cannot be passed to future generations.
This document discusses childhood diabetes mellitus. It is authored by Prof. Dr. Saad S Al- Ani, a pediatric consultant and head of the pediatric department at Khorfakkan Hospital in Sharjah, UAE. The document discusses that rates of both type 1 and type 2 diabetes are rising in children. It outlines symptoms of childhood diabetes like thirst, tiredness, weight loss, frequent urination, and behavioral issues. It also discusses treatment which primarily involves insulin therapy. Good glucose control and lifestyle changes are important for managing the condition. The prevalence of both type 1 and type 2 diabetes increased significantly in children over the last 5 years.
Diabetes in pregnancy poses risks to both mother and baby. Good glycemic control through nutrition, lifestyle changes, and possibly medication can help reduce risks. Babies of diabetic mothers may be large with potential birth injuries, and face risks of low blood sugar, breathing issues, and heart and metabolic problems. Close monitoring and management throughout pregnancy aims to deliver healthy babies.
This document summarizes various inborn errors of metabolism, including:
- Disorders of amino acid metabolism such as phenylketonuria (PKU), tyrosinemia, maple syrup urine disease (MSUD), homocystinuria, and nonketotic hyperglycinemia.
- Urea cycle defects which result in abnormal nitrogen metabolism and elevated ammonia levels.
- Disorders of organic acid metabolism including propionic acidemia, methylmalonic acidemia, isovaleric acidemia, and glutaric aciduria type 1.
- A disorder of fatty acid metabolism, medium-chain acyl-CoA dehydrogenase deficiency (MCAD), is also mentioned.
Hypoxic ischemic encephalopathy with a focus on recent advancesVarun Mamgain
This document discusses hypoxic ischemic encephalopathy (HIE), focusing on recent advances. It provides data on the scope of the problem, defining key terms like HIE, perinatal asphyxia, and neonatal encephalopathy. It discusses the etiology and risk factors for HIE, as well as the pathophysiology involving disrupted cerebral blood flow, energy metabolism, excitotoxicity, oxidative stress, inflammation, and apoptosis. Indian data on HIE is presented based on Apgar scores and neurological manifestations.
This document discusses thyroid disorders in children from birth to adolescence. It begins with an introduction on the anatomy and physiology of the thyroid gland and thyroid hormone biosynthesis. It then covers congenital hypothyroidism including screening, causes, clinical presentations, investigations and treatment. Transient congenital hypothyroidism and acquired hypothyroidism are also discussed. The document concludes with sections on thyrotoxicosis including investigations and treatment of thyrotoxicosis in children.
This document outlines immunology and immunity to infection. It discusses the immune system's role in fighting infection, including humoral immunity from B cells and cellular immunity from T cells. It also addresses intracellular and extracellular pathogens. The document then focuses on primary and secondary immunodeficiency, describing the types of primary immunodeficiencies including B cell, T cell, phagocytic, and complement defects. It provides guidance on clinical evaluation and diagnostic approach for patients with suspected immunodeficiency.
Congenital Adr Hyperplasia (CAH) can appear at any age from birth to puberty where it can lead to ambiguous genitalia. It is due to absolute or relative deficiency of 17 Hydroxylase or 21 Hydroxylase enzyme.
Edwards syndrome, also known as Trisomy 18, is a genetic disorder caused by the presence of an extra 18th chromosome. It results in physical abnormalities and intellectual disabilities. Individuals with Edwards syndrome often have heart defects, respiratory issues, and feeding difficulties. Prognosis is generally poor, with 50% surviving the first week and only 5-10% living beyond one year. Treatment focuses on management of symptoms and organ dysfunction. The condition is not inherited but rather caused by a random chromosomal error and cannot be passed to future generations.
This document discusses childhood diabetes mellitus. It is authored by Prof. Dr. Saad S Al- Ani, a pediatric consultant and head of the pediatric department at Khorfakkan Hospital in Sharjah, UAE. The document discusses that rates of both type 1 and type 2 diabetes are rising in children. It outlines symptoms of childhood diabetes like thirst, tiredness, weight loss, frequent urination, and behavioral issues. It also discusses treatment which primarily involves insulin therapy. Good glucose control and lifestyle changes are important for managing the condition. The prevalence of both type 1 and type 2 diabetes increased significantly in children over the last 5 years.
Diabetes in pregnancy poses risks to both mother and baby. Good glycemic control through nutrition, lifestyle changes, and possibly medication can help reduce risks. Babies of diabetic mothers may be large with potential birth injuries, and face risks of low blood sugar, breathing issues, and heart and metabolic problems. Close monitoring and management throughout pregnancy aims to deliver healthy babies.
This document summarizes various inborn errors of metabolism, including:
- Disorders of amino acid metabolism such as phenylketonuria (PKU), tyrosinemia, maple syrup urine disease (MSUD), homocystinuria, and nonketotic hyperglycinemia.
- Urea cycle defects which result in abnormal nitrogen metabolism and elevated ammonia levels.
- Disorders of organic acid metabolism including propionic acidemia, methylmalonic acidemia, isovaleric acidemia, and glutaric aciduria type 1.
- A disorder of fatty acid metabolism, medium-chain acyl-CoA dehydrogenase deficiency (MCAD), is also mentioned.
This document provides an overview of inborn errors of metabolism (IEM). It discusses that IEM have an overall incidence of 1 in 1000 to 1 in 2000 births. The most common presentation is sepsis in 30% of cases. IEM are classified based on the defective metabolic pathway, such as amino acid metabolism defects, carbohydrate metabolism defects, and organic acidemias. Clinical pointers for suspected IEM include deterioration after apparent normalcy, hypoglycemia, metabolic acidosis, abnormal urine odor, and dysmorphic features. Evaluation of neonates involves blood tests, blood gases, glucose and ammonia levels, urine analysis, and plasma amino acid analysis to identify specific disorders. Management involves identifying and limiting the offending substance
This document discusses neonatal hypoglycemia. It begins by explaining glucose physiology in fetuses and the adaptations required at birth. It then defines neonatal hypoglycemia and discusses the various etiologies including endocrine disorders, decreased substrate availability, and increased glucose utilization. Symptoms, screening, and management including prevention, treatment with oral feeds or IV therapy, and treatment of persistent or severe hypoglycemia are covered. The importance of aggressively managing hypoglycemia to prevent neurological damage is emphasized.
Hi Guys,
This presentation talks about Tuberculosis diagnosed in mother in the antenatal period, its treatment, implications on mother and fetus, the various protocols available currently regarding the neonatal management . Special focus being in major issues like breastmilk feeding, BCG, AKT prophylaxis, mother-child isolation.
Hope you find it useful.
P.S. - Please checkout my youtube channel - 'NEONATOHUB' & Facebook page 'Neonatohub' for lectures on neonatology.
This document discusses thyroid disorders in newborns. It covers thyroid physiology in the fetus and newborn, causes of congenital hypothyroidism including thyroid dysgenesis and dyshormonogenesis, clinical features of hypothyroidism, and methods for screening and diagnosis of congenital hypothyroidism in newborns. It also addresses transient hypothyroidism, sick euthyroid syndrome, and the importance of newborn screening to detect congenital hypothyroidism.
Prader-Willi syndrome (PWS) is a multisystemic complex genetic disorder.
PWS is relatively common with an estimated prevalence worldwide in the range of 1 in 10,000 to 30,000 individuals
Prader-Willi syndrome is due to absence of paternally expressed imprinted genes at 15q11.2-q13.
PWS was first described by Prader et al. in 1956 and it is the first recognized disorder related to genomic imprinting in humans.
PWS affects males and females with equal frequency and affects all races and ethnicities
Edward's Syndrome, also known as Trisomy 18, is a rare genetic disorder caused by the presence of an extra chromosome 18. It occurs in about 1 in 3,000 live births. Babies with Edward's Syndrome often have significant developmental delays and physical abnormalities. They frequently experience problems with their heart, brain, and other internal organs. Most infants with Edward's Syndrome do not survive past their first year due to issues with feeding and underlying health complications. While treatment aims to address any feeding difficulties or other medical needs, there is no cure for the condition.
Definition of neonatal sepsis,type of neonatal sepsis ,early onset neonatal sepsis,late onset neonatal sepsis,Pathophysiology of neonatal sepsis,,sign and symptoms of neonatal sepsis, diagnosis of neonatal sepsis,management of neonatal sepsis, antibiotic used for neonatal sepsis,prevention of neonatal sepsis, prognosis of neonatal sepsis ,and A summary
This document contains definitions and questions related to a neonatology end-of-posting test. It defines terms like perinatal mortality rate, neonatal mortality rate, and others. It also provides answers to questions about conditions like respiratory distress syndrome, transient tachypnea of the newborn, hypoglycemia, infections, and intracranial hemorrhage in newborns. Clinical signs, diagnostic tests, and management strategies are discussed. Survival rates by birth weight are also presented.
Growth charts in Neonates- Preterm and termSujit Shrestha
Growth charts in Newborn, Preterm and term neonates. All historically used charts in NICU are discussed here.
Presented by Dr Sujit, in Sir Ganga Ram Hospital
This document discusses intrauterine growth restriction (IUGR) and small for gestational age (SGA) infants. It defines IUGR as impaired fetal growth and SGA as weight below the 10th percentile. IUGR incidence in India is 3-10% of pregnancies and is associated with higher stillbirth and infant mortality rates. IUGR can be symmetric, asymmetric, or combined based on effects on weight, length, and head circumference. Etiologies include placental insufficiency, genetic factors, infections, and maternal health conditions. Complications include hypoglycemia, hypothermia, and immune dysfunction. Proper management involves antenatal diagnosis, skilled delivery and resuscitation, glucose monitoring, screening for
What is congenital nephrotic syndrome ,what is the definition of congenital nephrotic syndrome,what is the inheritance,what are the responsible genes ,what are the types of congenital nephrotic syndrome,what is the presentation ,diagnosis ,and treatment of congenital nephrotic syndrome, primary type and secondary type of congenital nephrotic syndrome
Pediatrics. trisomy 21. Meiotic non-disjunction of chromosome 21. clinical features and associated abnormalities of down syndrome. screening test for down syndrome. counseling for parents in down syndrome.
KAWASAKI DISEASE
History of Kawasaki disease
Epidemiology and etiology
Presentation and diagnosis
Treatment
Chronic cardiovascular manifestations
Follow up of patients
Questions in the chronic management
Some additional things to ask in the history:
- Family history of similar episodes or endocrine disorders
- Dietary history, including any changes in appetite/food intake
- Growth pattern and any slowing of growth
- Pubertal development
Some additional things to examine:
- Vital signs - check for signs of dehydration, shock
- Detailed physical exam looking for signs of other endocrine abnormalities
- Developmental assessment
- Nutritional status
Investigations to consider:
- Electrolytes, liver/renal function tests
- Cortisol, ACTH to check for primary adrenal insufficiency
- Thyroid function tests
- Growth hormone stimulation test
- Blood glucose curve/
1. A thorough evaluation of the dysmorphic child includes obtaining a detailed family, birth, and medical history as well as a comprehensive physical exam.
2. Minor anomalies and phenotypic variants can provide clues to narrow the differential diagnosis and include features such as epicanthal folds, clinodactyly, and pigmented nevi.
3. Additional diagnostic testing may include imaging studies like x-rays if skeletal abnormalities, and laboratory testing such as karyotyping to identify chromosomal abnormalities.
This document appears to be a powerpoint presentation about infants born to mothers with diabetes. It discusses the increased risks these infants face, including doubled risks of birth injuries and tripled risks of c-section delivery. It also summarizes some of the key slides in the presentation, which cover topics like the pathophysiology of diabetes in pregnancy, methods for screening and diagnosing diabetes, potential complications for both mother and infant, and common issues infant may experience due to hyperglycemia like macrosomia and birth defects. The presentation provides medical information to healthcare providers about caring for infants of diabetic mothers.
Turner syndrome is a genetic condition characterized by complete or partial monosomy of the X chromosome, affecting about 1 in 2,500-5,000 females. Clinical features include short stature, neck webbing, protruding ears, and gonadal dysgenesis leading to infertility. It is diagnosed through karyotyping and fetal ultrasound may suggest it. Treatment involves growth hormone therapy, estrogen replacement, and managing associated conditions such as hypothyroidism, diabetes, and heart problems. Prognosis is generally good with treatment, though individuals are often shorter and infertile.
This document discusses neonatal hypertension. It begins by outlining topics to be covered, including defining neonatal hypertension, measuring blood pressure in neonates, evaluating causes of hypertension, and managing hypertension. The document then focuses on questions about properly measuring blood pressure in neonates and common causes of neonatal hypertension such as renal issues. Evaluation and treatment of neonatal hypertension is also discussed, including initial testing, choosing antihypertensive medications, and considering long term outcomes. Blood pressure measurement techniques and normal ranges are emphasized.
Nephrotic syndrome is a kidney disorder characterized by massive edema, low albumin levels, high cholesterol, and heavy protein in urine. It most commonly affects children ages 2-6 years old and is more prevalent in boys. The primary type is idiopathic and thought to be autoimmune. It causes alterations to the glomerular membrane, increasing protein loss in urine. Symptoms include edema, ascites, weight gain, and fatigue. Diagnosis involves testing urine protein and albumin levels. Treatment focuses on steroids, diuretics, diet, and managing complications like infection.
This document provides information on diabetes mellitus (DM), including the different types of DM, complications of DM, diagnostic tests, treatment, and management. It begins by defining DM as a chronic condition characterized by hyperglycemia. It describes the three main types of DM - type 1 DM which results from an autoimmune destruction of the pancreas, type 2 DM which involves insulin resistance and relative lack of insulin production, and gestational DM which develops during pregnancy. It also outlines the acute complications of DM including hypoglycemia, diabetic ketoacidosis, and hyperglycemic hyperosmolar nonketotic syndrome. Long term complications from macrovascular and microvascular changes are also discussed.
This document provides an overview of inborn errors of metabolism (IEM). It discusses that IEM have an overall incidence of 1 in 1000 to 1 in 2000 births. The most common presentation is sepsis in 30% of cases. IEM are classified based on the defective metabolic pathway, such as amino acid metabolism defects, carbohydrate metabolism defects, and organic acidemias. Clinical pointers for suspected IEM include deterioration after apparent normalcy, hypoglycemia, metabolic acidosis, abnormal urine odor, and dysmorphic features. Evaluation of neonates involves blood tests, blood gases, glucose and ammonia levels, urine analysis, and plasma amino acid analysis to identify specific disorders. Management involves identifying and limiting the offending substance
This document discusses neonatal hypoglycemia. It begins by explaining glucose physiology in fetuses and the adaptations required at birth. It then defines neonatal hypoglycemia and discusses the various etiologies including endocrine disorders, decreased substrate availability, and increased glucose utilization. Symptoms, screening, and management including prevention, treatment with oral feeds or IV therapy, and treatment of persistent or severe hypoglycemia are covered. The importance of aggressively managing hypoglycemia to prevent neurological damage is emphasized.
Hi Guys,
This presentation talks about Tuberculosis diagnosed in mother in the antenatal period, its treatment, implications on mother and fetus, the various protocols available currently regarding the neonatal management . Special focus being in major issues like breastmilk feeding, BCG, AKT prophylaxis, mother-child isolation.
Hope you find it useful.
P.S. - Please checkout my youtube channel - 'NEONATOHUB' & Facebook page 'Neonatohub' for lectures on neonatology.
This document discusses thyroid disorders in newborns. It covers thyroid physiology in the fetus and newborn, causes of congenital hypothyroidism including thyroid dysgenesis and dyshormonogenesis, clinical features of hypothyroidism, and methods for screening and diagnosis of congenital hypothyroidism in newborns. It also addresses transient hypothyroidism, sick euthyroid syndrome, and the importance of newborn screening to detect congenital hypothyroidism.
Prader-Willi syndrome (PWS) is a multisystemic complex genetic disorder.
PWS is relatively common with an estimated prevalence worldwide in the range of 1 in 10,000 to 30,000 individuals
Prader-Willi syndrome is due to absence of paternally expressed imprinted genes at 15q11.2-q13.
PWS was first described by Prader et al. in 1956 and it is the first recognized disorder related to genomic imprinting in humans.
PWS affects males and females with equal frequency and affects all races and ethnicities
Edward's Syndrome, also known as Trisomy 18, is a rare genetic disorder caused by the presence of an extra chromosome 18. It occurs in about 1 in 3,000 live births. Babies with Edward's Syndrome often have significant developmental delays and physical abnormalities. They frequently experience problems with their heart, brain, and other internal organs. Most infants with Edward's Syndrome do not survive past their first year due to issues with feeding and underlying health complications. While treatment aims to address any feeding difficulties or other medical needs, there is no cure for the condition.
Definition of neonatal sepsis,type of neonatal sepsis ,early onset neonatal sepsis,late onset neonatal sepsis,Pathophysiology of neonatal sepsis,,sign and symptoms of neonatal sepsis, diagnosis of neonatal sepsis,management of neonatal sepsis, antibiotic used for neonatal sepsis,prevention of neonatal sepsis, prognosis of neonatal sepsis ,and A summary
This document contains definitions and questions related to a neonatology end-of-posting test. It defines terms like perinatal mortality rate, neonatal mortality rate, and others. It also provides answers to questions about conditions like respiratory distress syndrome, transient tachypnea of the newborn, hypoglycemia, infections, and intracranial hemorrhage in newborns. Clinical signs, diagnostic tests, and management strategies are discussed. Survival rates by birth weight are also presented.
Growth charts in Neonates- Preterm and termSujit Shrestha
Growth charts in Newborn, Preterm and term neonates. All historically used charts in NICU are discussed here.
Presented by Dr Sujit, in Sir Ganga Ram Hospital
This document discusses intrauterine growth restriction (IUGR) and small for gestational age (SGA) infants. It defines IUGR as impaired fetal growth and SGA as weight below the 10th percentile. IUGR incidence in India is 3-10% of pregnancies and is associated with higher stillbirth and infant mortality rates. IUGR can be symmetric, asymmetric, or combined based on effects on weight, length, and head circumference. Etiologies include placental insufficiency, genetic factors, infections, and maternal health conditions. Complications include hypoglycemia, hypothermia, and immune dysfunction. Proper management involves antenatal diagnosis, skilled delivery and resuscitation, glucose monitoring, screening for
What is congenital nephrotic syndrome ,what is the definition of congenital nephrotic syndrome,what is the inheritance,what are the responsible genes ,what are the types of congenital nephrotic syndrome,what is the presentation ,diagnosis ,and treatment of congenital nephrotic syndrome, primary type and secondary type of congenital nephrotic syndrome
Pediatrics. trisomy 21. Meiotic non-disjunction of chromosome 21. clinical features and associated abnormalities of down syndrome. screening test for down syndrome. counseling for parents in down syndrome.
KAWASAKI DISEASE
History of Kawasaki disease
Epidemiology and etiology
Presentation and diagnosis
Treatment
Chronic cardiovascular manifestations
Follow up of patients
Questions in the chronic management
Some additional things to ask in the history:
- Family history of similar episodes or endocrine disorders
- Dietary history, including any changes in appetite/food intake
- Growth pattern and any slowing of growth
- Pubertal development
Some additional things to examine:
- Vital signs - check for signs of dehydration, shock
- Detailed physical exam looking for signs of other endocrine abnormalities
- Developmental assessment
- Nutritional status
Investigations to consider:
- Electrolytes, liver/renal function tests
- Cortisol, ACTH to check for primary adrenal insufficiency
- Thyroid function tests
- Growth hormone stimulation test
- Blood glucose curve/
1. A thorough evaluation of the dysmorphic child includes obtaining a detailed family, birth, and medical history as well as a comprehensive physical exam.
2. Minor anomalies and phenotypic variants can provide clues to narrow the differential diagnosis and include features such as epicanthal folds, clinodactyly, and pigmented nevi.
3. Additional diagnostic testing may include imaging studies like x-rays if skeletal abnormalities, and laboratory testing such as karyotyping to identify chromosomal abnormalities.
This document appears to be a powerpoint presentation about infants born to mothers with diabetes. It discusses the increased risks these infants face, including doubled risks of birth injuries and tripled risks of c-section delivery. It also summarizes some of the key slides in the presentation, which cover topics like the pathophysiology of diabetes in pregnancy, methods for screening and diagnosing diabetes, potential complications for both mother and infant, and common issues infant may experience due to hyperglycemia like macrosomia and birth defects. The presentation provides medical information to healthcare providers about caring for infants of diabetic mothers.
Turner syndrome is a genetic condition characterized by complete or partial monosomy of the X chromosome, affecting about 1 in 2,500-5,000 females. Clinical features include short stature, neck webbing, protruding ears, and gonadal dysgenesis leading to infertility. It is diagnosed through karyotyping and fetal ultrasound may suggest it. Treatment involves growth hormone therapy, estrogen replacement, and managing associated conditions such as hypothyroidism, diabetes, and heart problems. Prognosis is generally good with treatment, though individuals are often shorter and infertile.
This document discusses neonatal hypertension. It begins by outlining topics to be covered, including defining neonatal hypertension, measuring blood pressure in neonates, evaluating causes of hypertension, and managing hypertension. The document then focuses on questions about properly measuring blood pressure in neonates and common causes of neonatal hypertension such as renal issues. Evaluation and treatment of neonatal hypertension is also discussed, including initial testing, choosing antihypertensive medications, and considering long term outcomes. Blood pressure measurement techniques and normal ranges are emphasized.
Nephrotic syndrome is a kidney disorder characterized by massive edema, low albumin levels, high cholesterol, and heavy protein in urine. It most commonly affects children ages 2-6 years old and is more prevalent in boys. The primary type is idiopathic and thought to be autoimmune. It causes alterations to the glomerular membrane, increasing protein loss in urine. Symptoms include edema, ascites, weight gain, and fatigue. Diagnosis involves testing urine protein and albumin levels. Treatment focuses on steroids, diuretics, diet, and managing complications like infection.
This document provides information on diabetes mellitus (DM), including the different types of DM, complications of DM, diagnostic tests, treatment, and management. It begins by defining DM as a chronic condition characterized by hyperglycemia. It describes the three main types of DM - type 1 DM which results from an autoimmune destruction of the pancreas, type 2 DM which involves insulin resistance and relative lack of insulin production, and gestational DM which develops during pregnancy. It also outlines the acute complications of DM including hypoglycemia, diabetic ketoacidosis, and hyperglycemic hyperosmolar nonketotic syndrome. Long term complications from macrovascular and microvascular changes are also discussed.
Type 1 diabetes is characterized by little or no insulin production due to destruction of pancreatic beta cells. It commonly develops in childhood or adolescence and requires lifelong insulin treatment. Symptoms include increased thirst, urination, hunger, and weight loss. Complications can include retinopathy, neuropathy, kidney disease and cardiovascular disease if not properly managed. Treatment involves frequent blood glucose monitoring, insulin administration, following a balanced diet, and regular exercise.
Diabetes Mellitus & Gestational D iabetes in Pregnancy Lifecare Centre
This document discusses diabetes and gestational diabetes in pregnancy. It covers pre-conception care for women with diabetes, including achieving optimal blood glucose control through diet and medication. It also discusses care during pregnancy such as frequent monitoring and surveillance of the fetus. Complications of uncontrolled diabetes during pregnancy for both mother and baby are outlined. The importance of postpartum care is also mentioned.
- Type 2 diabetes accounts for over 90% of diabetes cases worldwide and is associated with obesity, lack of exercise, and poor diet. It is managed through lifestyle modifications including diet, exercise, oral hypoglycemic medications, and sometimes insulin therapy.
- The main treatment approaches involve dietary changes to control blood sugar and weight, regular physical activity, oral medications like metformin and sulfonylureas, and potentially insulin therapy if blood sugar levels remain uncontrolled.
- Close monitoring of blood sugar levels through self-testing and HbA1c levels helps guide treatment adjustments and ensure proper management of the disease.
This document discusses diabetes pharmacotherapy. It provides an overview of the different types of diabetes, including type 1, type 2, gestational diabetes, and maturity onset diabetes of youth. It describes the pathogenesis and clinical presentation of type 1 and type 2 diabetes. The major components of diabetes treatment are diet, exercise, oral hypoglycemic medications, and insulin therapy. The document discusses the different types of insulin preparations, including their sources, structures, mechanisms of action, and uses. It provides guidance on calculating insulin doses and adjusting doses based on blood sugar levels.
This document provides information about diabetes mellitus (DM) and diabetic ketoacidosis (DKA). It discusses the main types of DM including type 1, type 2, and gestational diabetes. Type 1 results from pancreatic failure to produce insulin, type 2 from insulin resistance, and gestational occurs in pregnant women. Worldwide, 382 million people have DM. Management focuses on diet, exercise, medication and monitoring to control blood sugar levels. Insulin is used to treat type 1 and sometimes type 2 DM, while other classes of oral medications are also used to treat type 2.
This document provides information about diabetes mellitus (DM) and diabetic ketoacidosis (DKA). It discusses the main types of DM including type 1, type 2, and gestational diabetes. Type 1 results from pancreatic failure to produce insulin, while type 2 begins with insulin resistance and can later include insulin deficiency. Gestational diabetes occurs in pregnant women without prior history. The document also covers epidemiology, pathophysiology, diagnosis, management, treatment options including insulin, oral medications, diet/exercise, and complications of uncontrolled diabetes.
This was a lecture in the course "Significant Medical Conditions in Seniors" presented at Peer Learning in Chapel Hill, NC, USA in 2016 by Michael C. Joseph, MD, MPH.
Diabetes mellitus is a group of metabolic disorders characterized by high blood sugar. There are three main types: type 1 caused by lack of insulin production; type 2 caused by insulin resistance; and gestational diabetes during pregnancy. Type 1 is an autoimmune disease destroying insulin-producing cells. Type 2 risk factors include obesity, poor diet, lack of exercise, and genetics. Complications affect eyes, kidneys, nerves, feet, and cardiovascular system if not managed through diet, exercise, medication including insulin, and monitoring of blood sugar levels. Prevention focuses on healthy lifestyle habits.
Neonatal diabetes mellitus (NDM) is a rare form of diabetes that occurs in the first few months of life, with an estimated incidence of 1 in 90,000-160,000 live births. There are over 20 known genetic causes of NDM. Hyperglycemia in neonates is most commonly seen in the first few days after birth due to stress or excessive glucose administration. Treatment involves starting an intravenous insulin infusion when blood glucose levels persistently exceed 250 mg/dL. Genetic testing is recommended for cases of diabetes diagnosed before 12 months of age to determine the cause and best treatment approach. The most common genetic causes of NDM are alterations in the KCNJ11 and ABCC8 genes and chromosome 6
Diabetes mellitus is a disease caused by deficiency or diminished effectiveness of endogenous insulin. It is characterised by hyperglycaemia, deranged metabolism and sequelae predominantly affecting the vasculature.
A 52-year-old woman presented with unconsciousness for 1 hour. She has a 5-year history of type 2 diabetes that was not being treated with medication. On examination, she was severely dehydrated with low blood pressure and an elevated heart rate. Her blood sugar was very high at 21 mmol/L. She was diagnosed with diabetic ketoacidosis and treated with fluid replacement and insulin. Her condition stabilized and she was discharged on oral medications for diabetes.
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels. The document outlines the types of diabetes (type 1, type 2, gestational), risk factors, pathophysiology, clinical manifestations, complications and diagnostic tests. It provides definitions of diabetes, discusses the anatomy and physiology of the pancreas, classifications of diabetes, causes and risk factors, pathophysiology, clinical manifestations, complications, and diagnostic evaluations. The summary focuses on key information about the different types of diabetes.
The most common type of diabetes in children and teens is type 1 diabetes, also called juvenile diabetes. With type 1 diabetes, the pancreas does not produce insulin. Type 2 diabetes used to be called adult-onset diabetes but is becoming more common in children due to increases in obesity. Children with type 2 diabetes are at high risk if they are overweight, have a family history of diabetes, or are not physically active. Lifestyle changes like maintaining a healthy weight, being physically active, eating smaller portions of healthy foods, and limiting screen time can lower the risk of type 2 diabetes in children. Children with type 2 diabetes may be managed through diet and exercise alone, but some patients will need oral medications or insulin. Children with type
This document provides information on diabetes mellitus and its relevance to dental care. It defines diabetes, describes the different types, and lists common signs and symptoms. It also discusses diabetes complications, diagnosis, treatment planning for dental procedures, oral manifestations of diabetes, and dental management considerations. The goal is to educate dentists on properly treating and managing diabetic patients.
This document discusses diabetes mellitus in pregnancy. It defines gestational diabetes as impaired glucose tolerance first recognized during the second or third trimester of pregnancy. Risk factors include family history of diabetes, obesity, and age over 30. During pregnancy, placental hormones increase insulin resistance and antagonize insulin effectiveness, raising blood sugar levels and potentially leading to hyperglycemia. Proper management includes monitoring blood sugar via fasting and post-meal tests, exercise, and treatment with insulin or oral medications if needed to control glucose levels and minimize risks to both mother and fetus.
This document discusses diabetes mellitus in pregnancy. It defines gestational diabetes as impaired glucose tolerance first recognized during the second or third trimester of pregnancy. Risk factors include family history of diabetes, obesity, and age over 30. During pregnancy, placental hormones increase insulin resistance and antagonize insulin effectiveness, raising blood sugar levels and potentially leading to hyperglycemia. Proper management includes monitoring blood sugar via fasting and post-meal tests, exercise, and treatment with insulin or oral medications if needed to control glucose levels and minimize risks to both mother and fetus.
Neonatal hypoglycemia occurs when blood glucose levels drop dangerously low in newborns. It affects 5-15% of infants and can cause neurological damage if untreated. The document discusses the causes, signs, classifications, diagnosis, treatment and prevention of neonatal hypoglycemia. It emphasizes the importance of monitoring blood glucose levels in at-risk infants, providing IV dextrose or feeding to raise glucose, and supporting breastfeeding to help prevent hypoglycemia. Nursing care focuses on stabilizing blood glucose through nutrition and medical management.
Diabetes mellitus, disorder of carbohydrate metabolism characterized by impaired ability of the body to produce or respond to insulin and thereby maintain proper levels of sugar (glucose) in the blood.
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Similar to Transitory endocrine and metabolic disorders specific to newborn (20)
The CPMB certification by PMBAUSA.com is the best choice for individuals pursuing a career in medical billing. Its comprehensive training, industry recognition, accreditation, competitive advantage, adaptability, emphasis on ethical standards, and potential for career advancement make it the gold standard for those looking to excel in the field of medical billing.
This document provides guidance on using external cause of injury codes, including:
1. External cause codes describe the circumstances surrounding an injury, including how and where it occurred.
2. There are different types of external cause codes that describe how the injury happened, where it happened, what the patient was doing, and whether the intent was intentional or unintentional.
3. External cause codes are used with injury codes in ranges A00-T88 or Z00-Z99. The 7th character must match between the injury and external cause codes.
4. Examples are provided to demonstrate proper use of external cause codes according to the described guidelines.
This document provides an overview and summary of medicine codes in CPT. It discusses several categories of medicine codes including evaluations and management, modifiers, immunizations, psychiatry, end-stage renal disease, cardiology, pulmonary, and more. Codes are organized by specialty and service type, with notes on proper use and billing.
This document provides an overview of pathology and laboratory coding. It describes various areas of pathology including anatomical pathology, cytopathology, cytogenetics, microbiology, surgical pathology, and reproductive medicine procedures. For each area, it provides the code ranges and notes on how to report specific tests and procedures. It also provides examples of how to code common pathology cases.
Radiology uses medical imaging techniques like X-rays, ultrasound, CT, MRI and PET to diagnose and treat diseases. Radiography uses X-rays to view internal structures. Ultrasound uses sound waves to detect objects and for medical imaging. CT scans combine many X-ray images from different angles to produce cross-sectional images. MRI uses magnetic fields and radio waves to generate images of organs in the body. Procedures are coded based on the imaging technique used and whether contrast is used. Modifiers identify professional and technical components.
Dysphasia is a partial or complete impairment of communication abilities caused by brain injury, while aphasia is an inability to understand or form language due to damage to specific brain regions, typically from a stroke or head trauma. Agnosia is the inability to process sensory information like recognizing objects or sounds despite intact senses, while apraxia is difficulty performing motor tasks like movements when asked despite understanding instructions. Acalculia and agraphia involve impaired mathematical and writing abilities, respectively, from acquired neurological disorders.
This document discusses various symptoms and signs involving cognition, perception, emotional state, and behavior. It introduces somnolence, stupor, coma and other conditions like catatonia. The Glasgow Coma Scale is discussed as a standardized scale for assessing levels of consciousness from deep unconsciousness to full alertness. Other conditions mentioned include delirium, amnesia, vertigo, anosmia, and parosmia. The document concludes by listing relevant ICD-10 codes covering symptoms related to cognitive functions, awareness, dizziness, smell and taste disturbances, general sensations, emotional state, and appearance/behavior.
This document provides general symptoms and signs for various medical conditions organized by ICD-10-CM guidelines. It lists common symptoms like fever, headache, malaise, fatigue, convulsions, and shock. It also describes conditions such as leukemia, neutropenia, anorexia nervosa, polydipsia, polyphagia, cachexia, and nail clubbing. The document instructs medical coders on classifying these symptoms and signs using ICD-10-CM codes ranging from fever of unknown origin to generalized hyperhidrosis to unspecified illness.
This document provides guidelines for coding signs and symptoms as well as abnormal laboratory findings. It explains that R codes should be used when a definitive diagnosis has not been provided. The guidelines indicate that signs and symptoms codes should not be used if they are part of the disease process for a confirmed diagnosis. Coma scale codes and their proper sequencing is also outlined. Functional quadriplegia and coding considerations for HIV are briefly discussed.
This document discusses congenital malformations, deformations, and chromosomal abnormalities that are present at birth. It outlines various types of congenital anomalies based on the ICD-10-CM classification system, including those involving the nervous system, eye/ear/face, circulatory system, respiratory system, digestive system, genital organs, urinary system, musculoskeletal system, and chromosomal abnormalities. The guidelines specify that acquired diseases are excluded and there is no age restriction on patients.
This document discusses several congenital malformations of the respiratory system. It describes choanal atresia where the nasal passage is blocked, as well as laryngeal webs that block the larynx. It also mentions laryngoceles, which are air sacs connecting to the larynx that protrude in the neck. Congenital cystic lung diseases and agenesis of the lung, where it is partially or completely absent, can also occur. Various conditions like these that affect the nose, larynx, trachea, bronchi and lungs are classified in the ICD-10 coding system.
This document discusses several congenital malformations of the nervous system, including anencephaly, acephaly, microcephaly, congenital hydrocephalus, agyria, lissencephaly, and spina bifida. Anencephaly is the absence of a major portion of the brain, skull, and scalp that occurs during embryonic development. Microcephaly is a condition where the brain does not develop properly, resulting in a smaller than normal head. Congenital hydrocephalus is a condition where there is abnormal accumulation of cerebrospinal fluid within the brain, typically causing increased pressure inside the skull. Spina bifida is a birth defect where there is incomplete closing of the backbone and membranes
This presentation includes basic of PCOS their pathology and treatment and also Ayurveda correlation of PCOS and Ayurvedic line of treatment mentioned in classics.
How to Fix the Import Error in the Odoo 17Celine George
An import error occurs when a program fails to import a module or library, disrupting its execution. In languages like Python, this issue arises when the specified module cannot be found or accessed, hindering the program's functionality. Resolving import errors is crucial for maintaining smooth software operation and uninterrupted development processes.
How to Setup Warehouse & Location in Odoo 17 InventoryCeline George
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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How to Build a Module in Odoo 17 Using the Scaffold MethodCeline George
Odoo provides an option for creating a module by using a single line command. By using this command the user can make a whole structure of a module. It is very easy for a beginner to make a module. There is no need to make each file manually. This slide will show how to create a module using the scaffold method.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
2. INTRODUCTION
• It includes transitory endocrine and metabolic
disturbances caused by the infants response to maternal
endocrine and metabolic factors,or its adjustment to
extrauterine environment..
3. NEONATAL DIABETES MELLITUS
• Neonatal diabetes mellitus (NDM) is a monogenic form
of diabetes that occurs in the first 6 months of life. It is
a rare disease, occurring in only one in 100,000 to
500,000 live births. Infants with NDM do not produce
enough insulin, leading to an increase in blood glucose.
4. • NDM can be mistaken for the much more common type
1 diabetes, but type 1 diabetes usually occurs later than
the first 6 months of life.
• In about half of those with NDM, the condition is lifelong
and is called permanent neonatal diabetes
mellitus (PNDM).
5. CONGENITAL GOITER
• congenital goiter is a diffuse or nodular enlargement of
the thyroid gland present at birth. Thyroid hormone
secretion may be decreased, increased, or normal.
• Diagnosis is by confirming thyroid size with
ultrasonography.
• Treatment is thyroid hormone replacement when
hypothyroidism is the cause.
• Surgery is indicated when breathing or swallowing is
impaired.
6. NEONATAL TETANY
• Hypocalcemic tetany occurring in neonates or young infa
nts, due to transient functional hypoparathyroidism i
n consumption of cow's milk (high phosphorus content).
7. ICD-10-CM GUIDELINES
• Transitory disorders of carbohydrate metabolism specific
to newborn- P70
• Transitory neonatal disorders of calcium and magnesium
metabolism- P71
• Other transitory neonatal endocrine disorders- P72
8. • Other transitory neonatal electrolyte and metabolic
disturbances- P74
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