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ANATOMY OF TONGUE
PHYSIOLOGY OF GUSTATION
By: Dr.S.Kameshwaran.
Chemical Senses
- Taste & smell:
(Both determine the flavour of food)
Taste & smell are closely linked even though they
involve different receptors and receptive
processes.
Taste sensation
5 primary tastes
♥ Sour – stimulated by acids
♥ Sweet – stimulated by sugars, alcohols, some amino acid
♥ Bitter – stimulated by bases
♥ Salty – stimulated by metal ions
♥ Umami - Meaty or savory taste/ pleasant taste
Sensitivity of the taste buds in different
locations.
 Anterior tongue is
more sensitive to
sweet and salty
substances
 Posterior tongue is
more sensitive to bitter
substances.
 Lateral tongue is more
sensitive to sour
substances.
Taste Receptors:
 Taste receptors are known as ‘Chemoreceptors’
 Chemoreceptors housed in taste buds
 Taste receptors have life span of about 10 days
 In association with food intake, influence flow of
digestive juices and affect appetite
Taste buds located in:
 Tongue
 Epiglottis
 Soft Palate
 Pharynx
Taste buds
 Most are on the tongue.
 Taste buds present within Papillae of tongue
 The different types of papillaes are
 Filiform - rough, conical shape, few taste buds
 Fungiform – scattered; most numerous on sides and
tips
 Circumvallate –largest; least numerous; back of
tongue
Taste pore
 Opening through which fluids in mouth come into contact
with surface of receptor cells
Taste receptor cells
 Modified epithelial cells with surface folds called microvilli
 Plasma membrane of microvilli contain receptor sites that
bind selectively with chemical molecules

Click to edit Master text styles

Second level

Third level

Fourth level
»
Fifth level
Location and Structure of Taste Buds
Anatomy of Taste Buds
Taste Buds
ANATOMY OF TASTE BUDS
₡ 10,000 taste buds found on
tongue, soft palate & pharynx
₡ Taste buds consist of:
₡ ~50 receptor cells (type 3)
surrounded by supporting cells
₡ Basal cells (type 1 &2)
develop into supporting cells
then receptor cells
₡ Gustatory hairs project
through the taste pore
₡ Life span 10 days
ANATOMY OF TASTE BUDS
Taste information sent to the
CNS
via
Cranial nerves # 7, 9 & 10
to
The taste nucleus
(n. tractus solitarius)
to
Thalamus
to
Primary gustatory cortex
Taste Pathway
Chemicals in the food

Dissolute in Saliva

Contact with gustatory hair cells or receptor cells

Depolarization of taste cells

Generation of action potential in associated sensory
neuron

Relayed to the gustatory cortex

Recognition of Taste
Physiology of Taste
Clinical considerations
♠ Ageusia: Absence of sense of taste
♠ Dysgeusia: Disturbed sense of taste
♠ Hypogeusia: Diminshed sense of taste
♠ Hypergeusia: increased sense of taste
THANK U

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TONGUE - ANATOMY & PHYSIOLOGY OF GUSTATION - TASTE SENSATION For B.Pharm, Pharm.D, D.Pharm & Nursing

  • 1.  Click to edit Master subtitle style ANATOMY OF TONGUE PHYSIOLOGY OF GUSTATION By: Dr.S.Kameshwaran.
  • 2. Chemical Senses - Taste & smell: (Both determine the flavour of food) Taste & smell are closely linked even though they involve different receptors and receptive processes.
  • 3. Taste sensation 5 primary tastes ♥ Sour – stimulated by acids ♥ Sweet – stimulated by sugars, alcohols, some amino acid ♥ Bitter – stimulated by bases ♥ Salty – stimulated by metal ions ♥ Umami - Meaty or savory taste/ pleasant taste
  • 4. Sensitivity of the taste buds in different locations.  Anterior tongue is more sensitive to sweet and salty substances  Posterior tongue is more sensitive to bitter substances.  Lateral tongue is more sensitive to sour substances.
  • 5. Taste Receptors:  Taste receptors are known as ‘Chemoreceptors’  Chemoreceptors housed in taste buds  Taste receptors have life span of about 10 days  In association with food intake, influence flow of digestive juices and affect appetite Taste buds located in:  Tongue  Epiglottis  Soft Palate  Pharynx
  • 6. Taste buds  Most are on the tongue.  Taste buds present within Papillae of tongue  The different types of papillaes are  Filiform - rough, conical shape, few taste buds  Fungiform – scattered; most numerous on sides and tips  Circumvallate –largest; least numerous; back of tongue Taste pore  Opening through which fluids in mouth come into contact with surface of receptor cells Taste receptor cells  Modified epithelial cells with surface folds called microvilli  Plasma membrane of microvilli contain receptor sites that bind selectively with chemical molecules
  • 7.
  • 8.  Click to edit Master text styles  Second level  Third level  Fourth level » Fifth level Location and Structure of Taste Buds
  • 11. ANATOMY OF TASTE BUDS ₡ 10,000 taste buds found on tongue, soft palate & pharynx ₡ Taste buds consist of: ₡ ~50 receptor cells (type 3) surrounded by supporting cells ₡ Basal cells (type 1 &2) develop into supporting cells then receptor cells ₡ Gustatory hairs project through the taste pore ₡ Life span 10 days
  • 13. Taste information sent to the CNS via Cranial nerves # 7, 9 & 10 to The taste nucleus (n. tractus solitarius) to Thalamus to Primary gustatory cortex Taste Pathway
  • 14. Chemicals in the food  Dissolute in Saliva  Contact with gustatory hair cells or receptor cells  Depolarization of taste cells  Generation of action potential in associated sensory neuron  Relayed to the gustatory cortex  Recognition of Taste Physiology of Taste
  • 15. Clinical considerations ♠ Ageusia: Absence of sense of taste ♠ Dysgeusia: Disturbed sense of taste ♠ Hypogeusia: Diminshed sense of taste ♠ Hypergeusia: increased sense of taste