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Thyroid Gland Dysfunction
Badr AL-Jindan, BDS , MSc , Dip. ABOMS, FRCD(C )
Diplomate Of The American Board Of Oral And Maxillofacial Surgery
Fellow Of The Royal College Of Dentist Of Canada
Assistant professor, King Faisal university, AL-Khobar, Saudi Arabia
Adjunct professor, McGill university , Montreal, Canada
Objectives
• Hypothalamic -Pituitary-Thyroid Axis
• Thyroid dysfunction
– Etiology
– Clinical Manifestation
– Medical management
– Dental managements (modification)
– Management of associated emergencies
Hypothalamic -Pituitary-Thyroid
Axis
Thyroid function
•

Growth
–
–

•

Stature attainment
Promote bone formation and maturation

CNS
–

Prenatal ;,
•

–

Adult hood(
•
•

•

Resemble B adrenergic agonist

Metabolic rate
–
–

•

Hypo : decrease memory
Hyper: irritability

ANS
–

•

Hypo : mental retardation

basal metabolic rate
carbohydrate , proteins and fat metabolism

CVS
–

Increase cardiac output, increase O2 tissue delivery
Etiology
Hypothyroid

Hyperthyroid
Clinical Manifestation
Hypothyroid

Hyperthyroid
Clinical Manifestation
Hypothyroid

Hyperthyroid
Medical Assessment Of
Thyroid Dysfunction
Medical Management Of
Thyroid Dysfunction
Hyperthyroid
Hypothyroid
Dental Management Of
Thyroid Dysfunction
Dental Emergencies associated
with Thyroid Dysfunction
Thyroid Storm

Myxedema

fever (hallmark)
rapid heart rate nausea/vomiting
diarrhea
irregular heart beat
weakness
heart failure confusion/disorientation

Weakness
Confusion
Feeling cold
Low body temperature
Swelling of the body
Difficulty breathing

decrease thyroid hormone synthesis
control the heart rate (Beta blockers;
propranolol ))

I.V. fluids
Electrolytes replacement
correct the low thyroid hormone
I.V. steroids
Warming blanket
Glucose supplements (if the blood sugar
level is low)
treat underlying cause
Lower mortality compared to thyroid
storm

I.V steroids may be used to help support
the circulation.

mortality approached 100%. However,
now, with the use of aggressive
therapy ,death rate less than 20%.
Thyroid gland dysfunction 1

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Thyroid gland dysfunction 1