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Technologies

95 CUSTOMER CONTACTS
      http://youtu.be/B7dgEE_W9Iw
      http://youtu.be/l42Dgy3TtbY
The Team
Franchessa Sayler – Entrepreneurial Lead
• Chemistry Graduate Student (Ph.D. August 2012)
• Developed technology




Martin Bakker – Principle Investigator
• Associate Professor of Physical Chemistry
• 30 years research experience




Christopher Melton – I-Corps Mentor
• Chairman & CEO of The White Oak Group, Inc.
• 30 years of business experience
Catalysts
                Increase production yield
                   Decrease downtime
                 For chemical companies

 Catalyst increase chemical process rates
 90 % of all manufactured products
 $900 Billion

            Better Catalyst       = $$$
The Opportunity
                               Global Catalyst
                               Market =
Chemical                        $29.5 B
Catalyst
           Hydrogen Pd/C       • Emissions
           -ation   Catalyst
Market     Catalyst = $1.1 B
                               • Refinery
= $7 B     = $1.5 B            • Chemical
The Competition                        ThruPore’s Pd/C



 Raw
Material                     Product    Raw
                                       Material                     Product




   Problems:                               Solutions:
   • Clogging                              • 6x throughput
   • Severely reduced activity             • Highly active
   Decreased production                    Increased production
                =-$                                   = + $$
Business Canvas Version 1.0
                          Key                         Value                    Customer                    Customer
Key                       Activities                  Proposition              Relations                   Segments
Partners                  • Synthesis and                                      • Provide support &
                            characterization of                                  trouble-shooting to
                                                                                                          • Chemical
                            catalysts. (test          •   25-50 %                customers to ensure
                                                                                                            manufacturers
                            reaction)                                            catalysts perform.
                          • Getting
                                                          cheaper                                               • Fine chemicals
• Template supplier(s).                                                        • Optimize and
• Turn-key                  MVP/evaluation            •   superior               upgrade catalysts to
                                                                                                                • Commodity
                                                                                                                   chemicals
  manufacturer?             samples in hands of           performance            provide on-going
                                                                                                                       • Biofeed
• Distributor?              potential customers.
                          • Optimization for
                                                      •   more efficient         relationship
                                                                                                                       • Petrofeed
                                                                                 (catalysts are
                            individual customer           precious metal                                  • Pharmaceuticals
                                                                                 consumables not
                                                                                                          • Oil refining
                            needs.                        usage                  capital items)
                                                                                                          • Emissions control
                          • Quality control.
                          • Validate
                                                      •   higher               Channels                         • Mobile
                            environmental                 throughput                                            • Stationary
                                                                                Product info. Delivery:   • Plastic production
                            requirements              •   longer                       • sales calls      • Edible oils
                          • Validate IP
                                                          working                      • conferences      • Electrocatalysts
                          Key                             lifetime (>1 yr              • publications
                          Resources                                                    • trade shows
                                                          or 2x)                Product Delivery:
                          • Specialist expertise in
                                                                                       • From company
                            design, synthesis and
                                                                                       warehouse
                            characterization of
                                                                                Direct licensing
                            catalyst
                          • Space & equipment
Cost                                                                Revenue
Structure • Manufacturing plant. Inventory.                         Stream
           •   Marketing, production and R&D                                  • Sales direct to customers.
           •   Cost of templates                                              • Licensing and support fees.
           •   Cost of precious metal                                         • Will reprocessing be cost effective?
           •   Legal
           •   Licensing
Testing Our Value Propositions


95 CUSTOMER CONTACTS

  Research Catalysts, Inc.




              Applied Ceramics, INC.
What We Learned about Our Value
           Propositions


      25-50 % Cheaper
Less Precious Metal - Pharma
     Higher Throughput
      Working Lifetime
 Superior Performance!
     + Not Flammable
- Business Canvas Version 2.0
                         Key                         Value                     Customer                      Customer
Key                      Activities                  Proposition               Relations                     Segments
Partners                 • Synthesis and                                       • Provide support &        • Chemical
                           characterization of        25-50 %                    trouble-shooting to
                           catalysts. (test                                      customers to ensure
                                                                                                            manufacturers
                           reaction)                  cheaper                    catalysts perform.            • Fine
• Template               • Getting                                             • Optimize and                    chemicals
  supplier(s).             MVP/evaluation             superior                   upgrade catalysts to
• Contract                 samples in hands of                                   provide on-going
                                                                                                               • Commodity
  manufacturer?            potential customers.       performance                relationship                    chemicals
• Distributor?           • Optimization for                                      (catalysts are                     • Bio
                           individual customer        more efficient             consumables not
                           needs.                                                capital items)
                                                                                                                    • Petro
                         • Quality control.           precious metal                                      • Pharmaceuticals
                                                                               Channels
                         • Validate                   usage                                               • Oil refining?
                           environmental
                           requirements
                                                                               Product info. Delivery:    • Emissions
                                                      higher                          • sales calls
                         • Validate IP
                                                                                      • conferences         control
                                                      throughput                      • publications           • Mobile
                         Key Resources                                                • trade shows            • Stationary
                         • Specialist expertise in    longer working           Product Delivery:
                                                                                      • From company      • Plastic
                           design, synthesis and      lifetime (>1 yr
                           characterization of                                        warehouse             production
                           catalyst                   or 2x)                   Direct licensing           • Edible oils
                         • Space and equipment                                                    5
                                                                                                          • Electrocatalysts
Cost        •   Manufacturing plant. Inventory.                    Revenue
Structure   •   Marketing, production and R&D                      Stream • Sales direct to customers.
            •   Cost of templates                                            • Licensing and support fees.
            •   Cost of precious metal
            •   Legal                                                        • Will reprocessing be cost effective?
            •   Licensing
Thoughts on Customer Segments
  Commodity & Petrochemicals

             Learned
   Commodity & Petrochemicals:
      • Conservative
   Fine Chemical:
      • Smaller scale
      • Optimization opportunity
   Pharmaceuticals:
      • Buy retail
Catalyst
                 Distribution Food Chain
Catalyst

                          Catalyst
                          Company




                          Retailer




           Researcher                Process Engineer
- Business Canvas Version 4.0 -> SPLIT
                       Key                         Value                        Customer             Customer
  Key                  Activities                  Proposition                  Relations            Segments
  Partners             • Synthesis and                                          • Provide support
• Template
                         characterization of        Our supported catalyst
                                                                                  & trouble-          Need Early
                         catalysts (test            will be:
  supplier(s)            reaction)                  • 25-50 % cheaper             shooting.           Adopters!
                       • Getting                    • Higher throughput         • Upgrade catalysts • Chemical
• Contract                                          • Longer working
                         MVP/evaluation                                           to provide on-      manufacturers
  manufacturer           samples in hands of          lifetime (>1 yr. or 2x)     going relationship      • Commodity
• Distributor            potential customers        • Superior
                                                                                  (catalysts are            chemicals
                       • Optimization for           performance                                                • Biofeed
• Catalyst                                          • Easier to work with         consumables not
                         individual customer                                                                   • Petrofee
  company                needs                        (pellets and not            capital items)                  d
                       • Quality control              flammable)                                            • Fine chemicals
                                                    • Less precious metal
                                                                                Channels
                       • Validate                                                                      • Pharmaceuticals
                         environmental                usage (less metal in      Product Info.          • Refineries
                         requirements                 product & fewer           Delivery:                   • Crude oil
                       • Validate IP                  synthesis steps)
                                                                                     • sales calls          • Biomass
                       • Crush test                 • More efficient flow
                                                      (less crushing)                • conferences            refining
                       Key Resources               Superior                          • publications    • Emissions control
                       • Specialist expertise in                                     • trade shows           • Mobile
                         design, synthesis and     Performance –                Product Delivery:            • Stationary
                                                   More active and                                     • Plastic production
                         characterization of                                         • company         • Edible oils
                         catalyst                  more selective                    • distributor
                                                                                                 5     • Electrocatalysts
                       • Space and equipment

Cost                                                             Revenue
Structure •   Manufacturing plant. Inventory                     Stream •       Sales directly to customers
          •   Marketing, production and R&D
          •   Legal                                                      •      Licensing and technical support fees
          •   Licensing                                                  •      Reprocessing
          •   Lab space (UA = $20/ft2/yr.)                               •      Sales through distributor/catalog?
          •   Contract manufacturing
- Business Canvas for the Research Market

Key                Key               Value               Customer           Customer
Partners           Activities        Proposition         Relations          Segments

Template            MVP/evaluation Superior              Provide                Researchers
supplier(s)         samples in     Performance           technical
                    hands of                             support                 Fine
                    potential                                                    chemicals
Contract            customers      Easy to Use                                   research
manufacturer                                             Email new               Pharma
                    Address larger                       products                research
                                      Safer
                    markets
                                                                                 Contract
                   Key                                                           manufacturer
                                                         Channels
                   Resources                                                     research
                                                         Product
                     Space                               Delivery:
                                                           Distributors
                     Equipment                             Retailers 5
Cost                                           Revenue   Sales through
Structure Production                           Stream    distributor/retailer
           Licensing IP or buy templates
           Lab space (UA = $20/ft2/yr.)
                                                         Establish own brand
Revenue Model

  Small Volume              Medium Volume               Large Volume

      Retailer                    Direct                   Licensing
                                  Sales                   Agreements
                                                         and Royalties




Cost to customer: $18/g    Cost to customer: $10/g   Cost to Customer: TBD
Our revenue: 30-50%        Our revenue: 70-80%       Our revenue: $/license
                                                         + royalties
Supporting Slides
Key                     Key                    Value                   Customer            Customer
Partners                Activities             Proposition             Relations           Segments

                        • Build
 Contract                 credibility                                   Tech. Support
 manufacturer           • Optimization         Superior                                    Fine Chemicals
                          for individual       Performance              Catalyst
 Template                 customer                                                         Pharmaceuticals
                                                                        Upgrade
 supplier(s)            • Quality              Longer
                          control                                                          Fragrances
                                               Lifetime
                        • Crush test                                   Channels
                        • License IP                                                       Edible Oils
                                               Easier
                                                                       Product Delivery:
                        Key Resources
                                               Separation
                                                                            Company
                          Space
                                                                            Contract
                          Equipment                                         manufacturer
                                                                                     5

Cost                                                         Revenue
Structure                                                    Stream    Sales directly to customers
            •   Marketing and R&D staff
            •   Legal
            •   IP Licensing                                           Reprocessing Fee
            •   Lab space (UA = $20/ft2/yr.)
            •   Contract manufacturing
                                                                       Leasing Agreement?
Key                      Key                   Value                   Customer            Customer
Partners                 Activities            Proposition             Relations           Segments


                         • Build
  Contract                                                             Tech. Support
                           credibility         Superior                                     Commodity
  manufacturer           • Optimization        Performance             Catalyst             chemicals
                           for individual
  Catalyst                                                             Upgrade
  company                  customer
                         • Quality             More Active
                           control                                                          Refineries
                         • Crush test          Higher                  Channels
                                               Throughput
                                                                       Product Delivery:
                         Key Resources
                                                                            Company
                           Space
                                                                            Contract
                           Equipment                                        manufacturer
                                                                                     5

Cost                                                         Revenue
Structure                                                    Stream
            •   Marketing and R&D staff
            •   Legal                                             • Licensing and technical support fees
            •   Licensing                                         • Sales directly to customers
            •   Lab space (UA = $20/ft2/yr.)                      • Reprocessing fees or leasing
            •   Contract manufacturer                               agreement
ThruPore                Partners:
Technologies
               Hypothesis and Experiments

       Catalyst
      Companies
                     Research Catalysts, Inc.




      Contract
    Manufacturers




     Distributors
ThruPore              Partners:
Technologies           Results
  • Catalyst companies
     o Be careful!
  • Contract manufacturers
     o A lot of contacts with companies needing
       catalyst technology
     o Use catalyst for chemical production for their
       customers
     o Mutually beneficial
  • Distributors
     o Most “distributors” have their own catalyst
       product lines – be cautious
ThruPore
Technologies
                 What’s Next
 •   Find more possible partners
 •   Talk to more contract manufacturers
 •   Prototype for VC’s
 •   Establish catalytic properties
 •   Continue to refine cost estimates
 •   Pursue IP license




                                           T
                                           3
ThruPore       What is a Catalyst?
Technologies



                    … “a catalyst is a substance
                    that changes the rate of a
                    chemical reaction without
                    itself appearing into the
                    products.”
ThruPore           How a Catalyst Works
Technologies
                           H2 O
• Reactive         H-             H-
  Surface Area     H O=O          H    O=O
                    H-
  Very
                    H
  Important

• We have a
  Football Field
  in a Teaspoon




     Raw                                     Product
     Material
ThruPore       Competitive Landscape
Technologies


                Catalyst Suppliers      Sales


                         Umicore       $12.6 B


                    Johnson Matthey    $12.5 B


                      BASF Catalysts   $6.5 B


                       W. R. Grace     $1.9 B
Major Players in Chemical
        Catalysts




   1.66 B

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ThruPore NSF Final Presentation

  • 1. Technologies 95 CUSTOMER CONTACTS http://youtu.be/B7dgEE_W9Iw http://youtu.be/l42Dgy3TtbY
  • 2. The Team Franchessa Sayler – Entrepreneurial Lead • Chemistry Graduate Student (Ph.D. August 2012) • Developed technology Martin Bakker – Principle Investigator • Associate Professor of Physical Chemistry • 30 years research experience Christopher Melton – I-Corps Mentor • Chairman & CEO of The White Oak Group, Inc. • 30 years of business experience
  • 3. Catalysts Increase production yield Decrease downtime For chemical companies  Catalyst increase chemical process rates  90 % of all manufactured products  $900 Billion Better Catalyst = $$$
  • 4. The Opportunity Global Catalyst Market = Chemical $29.5 B Catalyst Hydrogen Pd/C • Emissions -ation Catalyst Market Catalyst = $1.1 B • Refinery = $7 B = $1.5 B • Chemical
  • 5. The Competition ThruPore’s Pd/C Raw Material Product Raw Material Product Problems: Solutions: • Clogging • 6x throughput • Severely reduced activity • Highly active Decreased production Increased production =-$ = + $$
  • 6. Business Canvas Version 1.0 Key Value Customer Customer Key Activities Proposition Relations Segments Partners • Synthesis and • Provide support & characterization of trouble-shooting to • Chemical catalysts. (test • 25-50 % customers to ensure manufacturers reaction) catalysts perform. • Getting cheaper • Fine chemicals • Template supplier(s). • Optimize and • Turn-key MVP/evaluation • superior upgrade catalysts to • Commodity chemicals manufacturer? samples in hands of performance provide on-going • Biofeed • Distributor? potential customers. • Optimization for • more efficient relationship • Petrofeed (catalysts are individual customer precious metal • Pharmaceuticals consumables not • Oil refining needs. usage capital items) • Emissions control • Quality control. • Validate • higher Channels • Mobile environmental throughput • Stationary Product info. Delivery: • Plastic production requirements • longer • sales calls • Edible oils • Validate IP working • conferences • Electrocatalysts Key lifetime (>1 yr • publications Resources • trade shows or 2x) Product Delivery: • Specialist expertise in • From company design, synthesis and warehouse characterization of Direct licensing catalyst • Space & equipment Cost Revenue Structure • Manufacturing plant. Inventory. Stream • Marketing, production and R&D • Sales direct to customers. • Cost of templates • Licensing and support fees. • Cost of precious metal • Will reprocessing be cost effective? • Legal • Licensing
  • 7. Testing Our Value Propositions 95 CUSTOMER CONTACTS Research Catalysts, Inc. Applied Ceramics, INC.
  • 8. What We Learned about Our Value Propositions 25-50 % Cheaper Less Precious Metal - Pharma Higher Throughput Working Lifetime Superior Performance! + Not Flammable
  • 9. - Business Canvas Version 2.0 Key Value Customer Customer Key Activities Proposition Relations Segments Partners • Synthesis and • Provide support & • Chemical characterization of 25-50 % trouble-shooting to catalysts. (test customers to ensure manufacturers reaction) cheaper catalysts perform. • Fine • Template • Getting • Optimize and chemicals supplier(s). MVP/evaluation superior upgrade catalysts to • Contract samples in hands of provide on-going • Commodity manufacturer? potential customers. performance relationship chemicals • Distributor? • Optimization for (catalysts are • Bio individual customer more efficient consumables not needs. capital items) • Petro • Quality control. precious metal • Pharmaceuticals Channels • Validate usage • Oil refining? environmental requirements Product info. Delivery: • Emissions higher • sales calls • Validate IP • conferences control throughput • publications • Mobile Key Resources • trade shows • Stationary • Specialist expertise in longer working Product Delivery: • From company • Plastic design, synthesis and lifetime (>1 yr characterization of warehouse production catalyst or 2x) Direct licensing • Edible oils • Space and equipment 5 • Electrocatalysts Cost • Manufacturing plant. Inventory. Revenue Structure • Marketing, production and R&D Stream • Sales direct to customers. • Cost of templates • Licensing and support fees. • Cost of precious metal • Legal • Will reprocessing be cost effective? • Licensing
  • 10. Thoughts on Customer Segments Commodity & Petrochemicals Learned Commodity & Petrochemicals: • Conservative Fine Chemical: • Smaller scale • Optimization opportunity Pharmaceuticals: • Buy retail
  • 11. Catalyst Distribution Food Chain Catalyst Catalyst Company Retailer Researcher Process Engineer
  • 12. - Business Canvas Version 4.0 -> SPLIT Key Value Customer Customer Key Activities Proposition Relations Segments Partners • Synthesis and • Provide support • Template characterization of Our supported catalyst & trouble- Need Early catalysts (test will be: supplier(s) reaction) • 25-50 % cheaper shooting. Adopters! • Getting • Higher throughput • Upgrade catalysts • Chemical • Contract • Longer working MVP/evaluation to provide on- manufacturers manufacturer samples in hands of lifetime (>1 yr. or 2x) going relationship • Commodity • Distributor potential customers • Superior (catalysts are chemicals • Optimization for performance • Biofeed • Catalyst • Easier to work with consumables not individual customer • Petrofee company needs (pellets and not capital items) d • Quality control flammable) • Fine chemicals • Less precious metal Channels • Validate • Pharmaceuticals environmental usage (less metal in Product Info. • Refineries requirements product & fewer Delivery: • Crude oil • Validate IP synthesis steps) • sales calls • Biomass • Crush test • More efficient flow (less crushing) • conferences refining Key Resources Superior • publications • Emissions control • Specialist expertise in • trade shows • Mobile design, synthesis and Performance – Product Delivery: • Stationary More active and • Plastic production characterization of • company • Edible oils catalyst more selective • distributor 5 • Electrocatalysts • Space and equipment Cost Revenue Structure • Manufacturing plant. Inventory Stream • Sales directly to customers • Marketing, production and R&D • Legal • Licensing and technical support fees • Licensing • Reprocessing • Lab space (UA = $20/ft2/yr.) • Sales through distributor/catalog? • Contract manufacturing
  • 13. - Business Canvas for the Research Market Key Key Value Customer Customer Partners Activities Proposition Relations Segments Template MVP/evaluation Superior Provide Researchers supplier(s) samples in Performance technical hands of support Fine potential chemicals Contract customers Easy to Use research manufacturer Email new Pharma Address larger products research Safer markets Contract Key manufacturer Channels Resources research Product Space Delivery: Distributors Equipment Retailers 5 Cost Revenue Sales through Structure Production Stream distributor/retailer Licensing IP or buy templates Lab space (UA = $20/ft2/yr.) Establish own brand
  • 14. Revenue Model Small Volume Medium Volume Large Volume Retailer Direct Licensing Sales Agreements and Royalties Cost to customer: $18/g Cost to customer: $10/g Cost to Customer: TBD Our revenue: 30-50% Our revenue: 70-80% Our revenue: $/license + royalties
  • 16. Key Key Value Customer Customer Partners Activities Proposition Relations Segments • Build Contract credibility Tech. Support manufacturer • Optimization Superior Fine Chemicals for individual Performance Catalyst Template customer Pharmaceuticals Upgrade supplier(s) • Quality Longer control Fragrances Lifetime • Crush test Channels • License IP Edible Oils Easier Product Delivery: Key Resources Separation Company Space Contract Equipment manufacturer 5 Cost Revenue Structure Stream Sales directly to customers • Marketing and R&D staff • Legal • IP Licensing Reprocessing Fee • Lab space (UA = $20/ft2/yr.) • Contract manufacturing Leasing Agreement?
  • 17. Key Key Value Customer Customer Partners Activities Proposition Relations Segments • Build Contract Tech. Support credibility Superior Commodity manufacturer • Optimization Performance Catalyst chemicals for individual Catalyst Upgrade company customer • Quality More Active control Refineries • Crush test Higher Channels Throughput Product Delivery: Key Resources Company Space Contract Equipment manufacturer 5 Cost Revenue Structure Stream • Marketing and R&D staff • Legal • Licensing and technical support fees • Licensing • Sales directly to customers • Lab space (UA = $20/ft2/yr.) • Reprocessing fees or leasing • Contract manufacturer agreement
  • 18. ThruPore Partners: Technologies Hypothesis and Experiments Catalyst Companies Research Catalysts, Inc. Contract Manufacturers Distributors
  • 19. ThruPore Partners: Technologies Results • Catalyst companies o Be careful! • Contract manufacturers o A lot of contacts with companies needing catalyst technology o Use catalyst for chemical production for their customers o Mutually beneficial • Distributors o Most “distributors” have their own catalyst product lines – be cautious
  • 20. ThruPore Technologies What’s Next • Find more possible partners • Talk to more contract manufacturers • Prototype for VC’s • Establish catalytic properties • Continue to refine cost estimates • Pursue IP license T 3
  • 21. ThruPore What is a Catalyst? Technologies … “a catalyst is a substance that changes the rate of a chemical reaction without itself appearing into the products.”
  • 22. ThruPore How a Catalyst Works Technologies H2 O • Reactive H- H- Surface Area H O=O H O=O H- Very H Important • We have a Football Field in a Teaspoon Raw Product Material
  • 23. ThruPore Competitive Landscape Technologies Catalyst Suppliers Sales Umicore $12.6 B Johnson Matthey $12.5 B BASF Catalysts $6.5 B W. R. Grace $1.9 B
  • 24. Major Players in Chemical Catalysts 1.66 B

Editor's Notes

  1. Scott: our supports will be more expensive; we are competing with cheap natural materials which cost little, ours are high tech materials have add considerable value to gain market share. We don’t yet have economies of scale. So we have to compete on quality
  2. Rxns that Pd/C can’t doRxns only purePdnanopart50 °C lower temp Simplify processesDisruptive technology
  3. Varied depending which industry we were talking to.
  4. Our Technol. adds the biggest value to large scale, flow through processesEstablished supplier with credibility
  5. This would be for sales through Distributor to Organic Chemists: assume that 10000 people countrywide doing organic research, assume each uses about 5g Pd/C per year, gives 50 kg of Pd/C year, and that we can get 20% of the market that’s 10 kg/year: we can make this ourselves, but would need some one to bottle and packageSafer has to do with possibly being able to prevent material bursting in flames
  6. Target batch scale processes: these include Pharma, Fragrances, Edible Oils and other small scale chemical production we don’t yet know about. Defining characteristic of this market is small to moderate scale, use batch processing methods. Since they use batch, flow characteristics are not an issue.The larger end of this market expects to get free samples for process development, since payoff comes from larger scale use.Lower Cost is an issue; but longer lifetime is a bigger factorNeeds to be robust under process conditions (stirring)Easier separation of catalyst after use means that the cost of reprocessing spent catalyst will be lower; would probably want a cut from the reprocessor.Safer has to do with possibly being able to make the material less likely to burst into flames
  7. These are the big boys; have a dedicated plant that uses a lot of catalyst: supply of catalyst is critical, so end user will want license and until we have credibility in the market will want to manufacture themselves.