The Incas ruled a large empire in western South America in the 15th and early 16th centuries. They originated in the Andes mountains of Peru, with their capital at Cuzco. Under leaders like Pachacuti, the Incas expanded their territory through conquest. At its height, the Inca Empire stretched along the Andes from Ecuador to Chile and included over 12 million people. The Incas developed an elaborate bureaucracy to govern their diverse territories and subjects. Francisco Pizarro and the Spanish conquistadors were ultimately able to defeat the Incas and take control of the empire in the 1530s, due in part to their superior weapons and the diseases they unwittingly introduced.