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Dr.Hamza Rayes
Dr.Hamza Rayes
Reasoning
Diagnosis
Management
Parietal Pleura     Chest Wall




  Visceral Pleura


                    Alveolus
Boyle's law:


                   1
     Volume
                Pressure
Pressure gradient:
Air will flow from a high pressure to low
  pressure down it is gradient
0 cm H2O




                           0 cm H2O




The atmospheric pressure will be considered as Zero for simplification
Surface tension:
5
                    6
       5
                                6
                                              7



                                                  7
As the lung enlarges, recoil increases;
As the lung gets smaller, recoil decreases.
Outward recoiling force of 5 meaning
The same but in opposite direction
Hence , the negative charge




                                       -5   -5
As a result the net force will
sum to Zero. -5
                                                       Alveolar elasticity
So no net change                 -5           -5   exerting a force of
                                                   recoil of approximately 5


                                      5

                                          5
-5     -5


  5
 0 cm H2O
       5
Begining of Inspiration:




            Inspiratory                                       Inspiratory
               Muscles                                           Muscles
                               -5                   -5



                                      0 cm H2O



    When this stretch ability reaches a maximum the inflow of air will eventually increase the
    intra alveolar pressure to reach zero equilibrating with atmospheric pressure
    Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Begining of Inspiration:




        Inspiratory                                              Inspiratory
           Muscles                                                  Muscles
                            -6                         -6



                                      0 cm H2O



    When this stretch ability reaches a maximum the inflow of air will eventually increase the
    intra alveolar pressure to reach zero equilibrating with atmospheric pressure
    Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Begining of Inspiration:




      Inspiratory                                                  Inspiratory
         Muscles                                                      Muscles
                         -7                              -7



                                      0 cm H2O



    When this stretch ability reaches a maximum the inflow of air will eventually increase the
    intra alveolar pressure to reach zero equilibrating with atmospheric pressure
    Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Beginning of Inspiration:




Inspiratory                                                Inspiratory
   Muscles                                                    Muscles
                   -8                           -8


                                5

                                     5



          Which is obviously higher that the recoil force of 5
Beginning of Inspiration:




Inspiratory                                                  Inspiratory
   Muscles                                                      Muscles
                   -8                          -8



                           5

                                         5


        So the alveolus and the small air ways will expand
Inspiration
                    0 cm H2O




Inspiratory                          Inspiratory
   Muscles                              Muscles
               -8               -8


                    0 cm H2O

                    -1 cm H2O
Inspiration
                    0 cm H2O




Inspiratory                          Inspiratory
   Muscles                              Muscles
               -8               -8



                    -1 cm H2O
Inspiration
                                      0 cm H2O




Inspiratory                                                                Inspiratory
   Muscles                                                                    Muscles
                      -8                                     -8



                                      -1 cm H2O



        As the air accumulates inside the alveolus the pressure do not increase because
        the alveoli stretches and gets bigger
Inspiration
                                      0 cm H2O




Inspiratory                                                                Inspiratory
   Muscles                                                                    Muscles
                      -8                                     -8



                                      -1 cm H2O



        As the air accumulates inside the alveolus the pressure do not increase because
        the alveoli stretches and gets bigger
Inspiration
                                      0 cm H2O




Inspiratory                                                                Inspiratory
   Muscles                                                                    Muscles
                      -8                                     -8



                                      -1 cm H2O



        As the air accumulates inside the alveolus the pressure do not increase because
        the alveoli stretches and gets bigger
End of Inspiration
                                      0 cm H2O




Inspiratory                                                                Inspiratory
   Muscles                                                                    Muscles
                      -8                                     -8



                                      0cm H2O



        As the air accumulates inside the alveolus the pressure do not increase because
        the alveoli stretches and gets bigger
This stretchibility can be professionally
 designated as Compliance volume/pressure
This stretchibility can be professionally
 designated as Compliance.


                                      1
      Compliance
                                  Lung Recoil
Decreased compliance:
          Surfactant
          Lung Fibrosis
          Pulmonary HTN
          Laparoscopic Gas
          Lithtomyposition
This stretchibility can be professionally
 designated as Compliance.


                                        1
      Compliance
                                   Lung Recoil
                                    +
Surface Tension & Elastic tissue
This stretchibility can be professionally
 designated as Compliance.


                                        1
      Compliance
                                   Lung Recoil
      Surfactant
                                    +
            -
Surface Tension & Elastic tissue
Decreased compliance:
          Surfactant
          Lung Fibrosis
          Pulmonary HTN
          Laparoscopic Gas
          Lithtomy position
Increased compliance:
           Emphysema ( elastin)
           Asthma ?
           Saline
           Age

   Compliance
                              1
                         Lung Recoil
                              +
   Surface Tension & Elastic tissue
Lung   0.1 L / cmH20   Chest
End of Inspiration
                                        0 cm H2O




Inspiratory                                                                  Inspiratory
   Muscles                                                                      Muscles
                        -8                                     -8

                                   5
                                        0cm H2O

                                                    5
      When this stretchability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
End of Inspiration
                                        0 cm H2O




Inspiratory                                                                   Inspiratory
   Muscles                                                                       Muscles
                        -8                                     -8

                                   8
                                        0cm H2O

                                                    8
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
0 cm H2O




0 cm H2O
0 cm H2O   0 cm H2O




0 cm H2O   1- cm H2O
0 cm H2O   1 cm H2O




0 cm H2O   0 cm H2O
Begining of expiration
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -8                                     -8

                                   8
                                        0cm H2O

                                                    8
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Begining of expiration
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -7                                     -7

                                   8
                                        0cm H2O

                                                    8
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Begining of expiration
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -6                                     -6

                                   8
                                        0cm H2O

                                                    8
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Begining of expiration
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -5                                     -5

                                   8
                                        0cm H2O

                                                    8
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Begining of expiration
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -5                                     -5


                                       5
                                        0cm H2O

                                                   5
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Expiration:
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -5                                     -5


                                       5
                                        1cm H2O

                                                   5
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
Expiration:
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -5                                     -5


                                       5
                                        1 cm H2O

                                                   5
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
End of Expiration:
                                        0 cm H2O



Relaxation                                                                     Relaxation
Inspiratory                                                                    Inspiratory
   Muscles                                                                     Muscles
                        -5                                     -5


                                       5
                                        0cm H2O

                                                   5
      When this stretch ability reaches a maximum the inflow of air will eventually increase the
      intra alveolar pressure to reach zero equilibrating with atmospheric pressure
      Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
5
                 5
             5
                     5
                         5

emphysema
                             5
CPAP PEEP
CPAP PEEP
Total Ventilation ( Minute Ventilation )

  Tidal Volume x Respiratory Rate
Approximately the weight of the patient in Pounds
      Ex. A 100 pounds patient will have a dead space
                        of 100 ml



Dead space
Alveolar Ventilation:
 TV – Dead space x RR
Thank you
Lange Pulmonary Physiology
Basics of Anesthesia ( Miller )
Board Review Series
http://emsstaff.buncombecounty.org
http://www.uams.edu
http://www.anaesthetist.com
http://www.ncbi.nlm.nih.gov

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The art of breathing

  • 3.
  • 5. Parietal Pleura Chest Wall Visceral Pleura Alveolus
  • 6. Boyle's law: 1 Volume Pressure
  • 7. Pressure gradient: Air will flow from a high pressure to low pressure down it is gradient
  • 8. 0 cm H2O 0 cm H2O The atmospheric pressure will be considered as Zero for simplification
  • 9.
  • 11. 5 6 5 6 7 7 As the lung enlarges, recoil increases; As the lung gets smaller, recoil decreases.
  • 12. Outward recoiling force of 5 meaning The same but in opposite direction Hence , the negative charge -5 -5
  • 13. As a result the net force will sum to Zero. -5 Alveolar elasticity So no net change -5 -5 exerting a force of recoil of approximately 5 5 5
  • 14. -5 -5 5 0 cm H2O 5
  • 15. Begining of Inspiration: Inspiratory Inspiratory Muscles Muscles -5 -5 0 cm H2O When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 16. Begining of Inspiration: Inspiratory Inspiratory Muscles Muscles -6 -6 0 cm H2O When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 17. Begining of Inspiration: Inspiratory Inspiratory Muscles Muscles -7 -7 0 cm H2O When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 18. Beginning of Inspiration: Inspiratory Inspiratory Muscles Muscles -8 -8 5 5 Which is obviously higher that the recoil force of 5
  • 19. Beginning of Inspiration: Inspiratory Inspiratory Muscles Muscles -8 -8 5 5 So the alveolus and the small air ways will expand
  • 20. Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 0 cm H2O -1 cm H2O
  • 21. Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 -1 cm H2O
  • 22.
  • 23. Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 -1 cm H2O As the air accumulates inside the alveolus the pressure do not increase because the alveoli stretches and gets bigger
  • 24. Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 -1 cm H2O As the air accumulates inside the alveolus the pressure do not increase because the alveoli stretches and gets bigger
  • 25. Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 -1 cm H2O As the air accumulates inside the alveolus the pressure do not increase because the alveoli stretches and gets bigger
  • 26. End of Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 0cm H2O As the air accumulates inside the alveolus the pressure do not increase because the alveoli stretches and gets bigger
  • 27. This stretchibility can be professionally designated as Compliance volume/pressure
  • 28. This stretchibility can be professionally designated as Compliance. 1 Compliance Lung Recoil
  • 29. Decreased compliance: Surfactant Lung Fibrosis Pulmonary HTN Laparoscopic Gas Lithtomyposition
  • 30. This stretchibility can be professionally designated as Compliance. 1 Compliance Lung Recoil + Surface Tension & Elastic tissue
  • 31. This stretchibility can be professionally designated as Compliance. 1 Compliance Lung Recoil Surfactant + - Surface Tension & Elastic tissue
  • 32. Decreased compliance: Surfactant Lung Fibrosis Pulmonary HTN Laparoscopic Gas Lithtomy position
  • 33. Increased compliance: Emphysema ( elastin) Asthma ? Saline Age Compliance 1 Lung Recoil + Surface Tension & Elastic tissue
  • 34.
  • 35. Lung 0.1 L / cmH20 Chest
  • 36. End of Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 5 0cm H2O 5 When this stretchability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 37. End of Inspiration 0 cm H2O Inspiratory Inspiratory Muscles Muscles -8 -8 8 0cm H2O 8 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 38. 0 cm H2O 0 cm H2O
  • 39. 0 cm H2O 0 cm H2O 0 cm H2O 1- cm H2O
  • 40. 0 cm H2O 1 cm H2O 0 cm H2O 0 cm H2O
  • 41.
  • 42. Begining of expiration 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -8 -8 8 0cm H2O 8 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 43. Begining of expiration 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -7 -7 8 0cm H2O 8 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 44. Begining of expiration 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -6 -6 8 0cm H2O 8 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 45. Begining of expiration 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -5 -5 8 0cm H2O 8 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 46. Begining of expiration 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -5 -5 5 0cm H2O 5 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 47. Expiration: 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -5 -5 5 1cm H2O 5 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 48. Expiration: 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -5 -5 5 1 cm H2O 5 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 49. End of Expiration: 0 cm H2O Relaxation Relaxation Inspiratory Inspiratory Muscles Muscles -5 -5 5 0cm H2O 5 When this stretch ability reaches a maximum the inflow of air will eventually increase the intra alveolar pressure to reach zero equilibrating with atmospheric pressure Meanwhile, as the alveoli stretches it increases its recoil force from 5 to 8 cmH2O
  • 50. 5 5 5 5 5 emphysema 5
  • 52.
  • 53.
  • 54.
  • 56. Total Ventilation ( Minute Ventilation ) Tidal Volume x Respiratory Rate
  • 57. Approximately the weight of the patient in Pounds Ex. A 100 pounds patient will have a dead space of 100 ml Dead space
  • 58.
  • 59.
  • 60.
  • 61.
  • 62.
  • 63. Alveolar Ventilation: TV – Dead space x RR
  • 64.
  • 65.
  • 66.
  • 68. Lange Pulmonary Physiology Basics of Anesthesia ( Miller ) Board Review Series http://emsstaff.buncombecounty.org http://www.uams.edu http://www.anaesthetist.com http://www.ncbi.nlm.nih.gov