Terpenoids Cucurbitacin.pptx
•Download as PPTX, PDF•
2 likes•304 views
The terpenoids sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenoids. Terpenoids are hydrocarbons of plant origin of the general formula (C5H8)n as well as their originated, hydrogen and dehydrogenated derivatives. Plant terpenoids are used for their aromatic qualities and play a role in traditional herbals remedies. Cucurbitacin is a bitter-tasting principle that can be isolated from members of family Cucurbitaceae, such as cucumber (Cucumis sativus) and melon (Cucumis melo). In particular, cucurbitacin and momordicine, which have an intensly bitter taste, are content abundantly in Momordica charantia. There are more than 18 kinds of cucurbitacin and among them cucurbitacin B is a typical component.
Report
Share
Report
Share
Recommended
Coumarin and terpenoids
coumarin; umbelliferone and its biosynthesis and isolation.
terpenoide; cucurbitacine and its biosynthesis and isolation purification and characterization
Herbal formulations – current challenges in upgradation and modernization
This document discusses challenges facing the herbal medicine industry in India. It notes that while India has a large number of medicinal plants and a herbal industry worth $10 billion annually, it only has 2% of the global herbal market share due to several key issues. These include a lack of scientific validation and standardization of herbal medicines, limited quality regulation, insufficient evidence-based studies on efficacy and safety, and a lack of pharmacokinetic research on herbal compounds. Addressing these challenges would help India capture a larger share of the global herbal market.
Topic: Herbal Drug Industry
INDUSTRIAL PHARMACOGNOSTICAL TECHNOLOGY
Herbal drug industry: Infrastructure of herbal drug industry
involved in production of standardized extracts and various
dosage forms. Current challenges in upgrading and
modernization of herbal formulations. Entrepreneurship
Development, Project selection, project report, technical
knowledge, Capital venture, plant design, layout and construction.
Pilot plant scale –up techniques, case studies of herbal extracts.
Formulation and production management of herbals.
Plant Drug Cultivation
Unit I: Plant Drug Cultivation
General introduction to the importance of
Pharmacognosy in herbal drug industry, Indian Council of
Agricultural Research, Current Good Agricultural Practices,
Current Good Cultivation Practices, Current Good Collection
Practices, Conservation of medicinal plants- Ex-situ and Insitu
conservation of medicinal plants.
Structure elucidation phyto .pptx
1. The document discusses the structure elucidation of various compounds including carvone, citral, menthol, luteolin, kaempferol, nicotine, caffeine, and glycyrrhizin.
2. Various analytical techniques are described such as UV, IR, mass spectroscopy, and NMR that are used to determine the structure of these compounds.
3. The uses of these compounds are also mentioned including as flavorings, fragrances, medicines, and supplements.
Plant drug cultivation- Durgashree Diwakar
Pharmacognosy is the objective study of crude drugs of animal, vegetable and mineral origin, treated scientifically.
Pharmacognosy is the study of medicine derived from natural sources that include plants, animals, and microorganisms, and the scope of the field depends on knowledge about the safety, purity, and efficacy of complex multicompound products.
Herbal pharmacognosy is the application of this science specifically to traditional herbal medicine sources.
WITHANOLIDES AND UMBELLIFERONE TEJU.pptx
This document provides information about withanolides and umbelliferone. It discusses their biological sources, properties, biosynthesis, extraction, isolation, uses, and characterization. Withanolides are steroidal lactones found in ashwagandha that have anti-cancer and anti-inflammatory properties. Umbelliferone is a yellow coumarin found in plants like carrot and coriander that exhibits blue fluorescence and is used as an indicator in chemical tests. The document outlines methods for extracting, isolating, and identifying these compounds using techniques like column chromatography, TLC, UV-Vis, IR, NMR, and mass spectroscopy.
Marine Pharmacognosy.
Marine natural products: General methods of isolation and
purification, Study of Marine toxins, Recent advances in research
in marine drugs, Problems faced in research on marine drugs
such as taxonomical identification, chemical screening and their
solution.
Recommended
Coumarin and terpenoids
coumarin; umbelliferone and its biosynthesis and isolation.
terpenoide; cucurbitacine and its biosynthesis and isolation purification and characterization
Herbal formulations – current challenges in upgradation and modernization
This document discusses challenges facing the herbal medicine industry in India. It notes that while India has a large number of medicinal plants and a herbal industry worth $10 billion annually, it only has 2% of the global herbal market share due to several key issues. These include a lack of scientific validation and standardization of herbal medicines, limited quality regulation, insufficient evidence-based studies on efficacy and safety, and a lack of pharmacokinetic research on herbal compounds. Addressing these challenges would help India capture a larger share of the global herbal market.
Topic: Herbal Drug Industry
INDUSTRIAL PHARMACOGNOSTICAL TECHNOLOGY
Herbal drug industry: Infrastructure of herbal drug industry
involved in production of standardized extracts and various
dosage forms. Current challenges in upgrading and
modernization of herbal formulations. Entrepreneurship
Development, Project selection, project report, technical
knowledge, Capital venture, plant design, layout and construction.
Pilot plant scale –up techniques, case studies of herbal extracts.
Formulation and production management of herbals.
Plant Drug Cultivation
Unit I: Plant Drug Cultivation
General introduction to the importance of
Pharmacognosy in herbal drug industry, Indian Council of
Agricultural Research, Current Good Agricultural Practices,
Current Good Cultivation Practices, Current Good Collection
Practices, Conservation of medicinal plants- Ex-situ and Insitu
conservation of medicinal plants.
Structure elucidation phyto .pptx
1. The document discusses the structure elucidation of various compounds including carvone, citral, menthol, luteolin, kaempferol, nicotine, caffeine, and glycyrrhizin.
2. Various analytical techniques are described such as UV, IR, mass spectroscopy, and NMR that are used to determine the structure of these compounds.
3. The uses of these compounds are also mentioned including as flavorings, fragrances, medicines, and supplements.
Plant drug cultivation- Durgashree Diwakar
Pharmacognosy is the objective study of crude drugs of animal, vegetable and mineral origin, treated scientifically.
Pharmacognosy is the study of medicine derived from natural sources that include plants, animals, and microorganisms, and the scope of the field depends on knowledge about the safety, purity, and efficacy of complex multicompound products.
Herbal pharmacognosy is the application of this science specifically to traditional herbal medicine sources.
WITHANOLIDES AND UMBELLIFERONE TEJU.pptx
This document provides information about withanolides and umbelliferone. It discusses their biological sources, properties, biosynthesis, extraction, isolation, uses, and characterization. Withanolides are steroidal lactones found in ashwagandha that have anti-cancer and anti-inflammatory properties. Umbelliferone is a yellow coumarin found in plants like carrot and coriander that exhibits blue fluorescence and is used as an indicator in chemical tests. The document outlines methods for extracting, isolating, and identifying these compounds using techniques like column chromatography, TLC, UV-Vis, IR, NMR, and mass spectroscopy.
Marine Pharmacognosy.
Marine natural products: General methods of isolation and
purification, Study of Marine toxins, Recent advances in research
in marine drugs, Problems faced in research on marine drugs
such as taxonomical identification, chemical screening and their
solution.
Steroids Hecogenin.pptx
This topic covers the notes for unit 1 of phytochemistry in 1st semester in M Pharm of department of pharmacognosy. This includes biosynthesis, characterization, purification and uses of steroids.
Analytical profile of herbal drug.pptx
The document describes Andrographis paniculata, its extraction process, chemical constituents, and products. It discusses the extraction of andrographolide from the herb and describes the final products - andrographis paniculata dry extract and andrographolide. It also provides identification tests and specifications for these products.
Regulatory Asspects
Establishing a herbal drug industry requires navigating complex regulatory requirements related to safety, efficacy, quality and public health. Key aspects include complying with Good Manufacturing Practices, obtaining product licenses by submitting data on safety and efficacy to regulatory authorities, adhering to labeling and packaging guidelines, implementing quality control testing, monitoring adverse events, and ensuring compliance with international standards such as those of the International Conference on Harmonisation. Meeting these regulatory standards contributes to the success, credibility and public health impact of the herbal drug industry.
Phytopharmaceuticals- Durgashree Diwakar
A purified and standardized fraction with a defined minimum of four bioactive or phytochemical compounds of an extract of a medicinal plant or its part, for internal or external use of human beings or animals for diagnosis, treatment, mitigation, or prevention of any diseases but does not include administration by parenteral route.
Coumarin & Terpenoids
Biosynthesis, Isolation, Characterization, Purification, Structure Identification & Uses of
Coumarins :- Umbelliferone
Terpenoids :- Cucurbitacin
Health drinks by Nabarun Mukhopadhyay
This document discusses several natural health drinks including acai berry juice, green tea, goji berry juice, noni fruit juice, amla juice, and wheatgrass juice. It describes the source and botanical information for each drink, provides their nutritional composition, and lists their various health benefits such as increased energy, improved immune function, antioxidant effects, and more. The document concludes by citing several references for further information on the health impacts of these natural beverages.
MARINE NATURAL PRODUCTS P.P.T..ppsx
The document presents information on marine natural products. It discusses how marine organisms like algae, sponges and corals produce biologically active compounds with properties like anti-cancer, anti-inflammatory and antimicrobial effects. It describes methods used to isolate and purify compounds from marine sources, as well as challenges in marine drug research like taxonomic identification and chemical screening. Recent advances in marine drugs for conditions like cancer, inflammation and infections are also summarized. Finally, it briefly discusses marine toxins produced by some marine species that can cause illnesses in humans.
Drug discovery and Devlp- Durgashree Diwakar
Drug discovery is the process through which potential new medicines are identified.
It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology.
Natural products and their structural analogues have historically made a major contribution to pharmacotherapy, especially for cancer and infectious diseases.
Natural products also have challenges for drug discovery, such as technical barriers to screening, isolation, characterization and optimization.
Analytical profiling of herbal drugs
analytical profiling (HPTLC, HPLC and UV spectroscopy) of Curcuma lomga, Embelica officinalis and Psoralea Corylifolia
Extraction, isolation & estimation of ephedrine
This document describes the extraction, isolation, and estimation of ephedrine from Ephedra gerardiana and other Ephedra species. It involves powdering the dried stems and extracting with petroleum ether and aqueous alcohol. The extract is made alkaline and filtered to obtain a dry ephedrine residue. Estimation of ephedrine involves thin layer chromatography and high performance thin layer chromatography with solvent systems and visualization with ninhydrin reagent. Ephedrine content was estimated to be a maximum of 2.60% using a calibration curve. Ephedrine is used as a bronchodilator for asthma and to treat low blood pressure, with oral and parenteral doses provided.
Recent Advances in Extraction
Extraction of Phytochemicals
recent advances in extraction
Choice of solvent
Selection of method
Successive and exhaustive extraction
Nutraceuticals (Durgashree).pptx
The document discusses various types of nutraceuticals, including inorganic mineral supplements like calcium, magnesium, and zinc; vitamin supplements; digestive enzymes; dietary fibers; cereals and grains; antioxidants; polyunsaturated fatty acids; health drinks from natural sources like fruits, tea, and soy; and wines. It provides examples and health benefits of each category in 1-3 sentences and covers a wide range of nutraceutical topics over 12 pages.
Plants drug cultivation(Pharmacognosy)
Plants Drug Cultivation:
General introduction to importance pharmacognosy.
Indian Council of Agricultural Research.
Current good agricultural practices.
Current good cultivation practices
Current good collection practices.
Conservation of medicinal plants-Ex-situ & In-situ conservation of medicinal plants.
MEDICINAL PLANT BIOTECHNOLOGY UNIT 5, MPG, SEM 2 FERMENTATION TECHNOLOGY.pptx
MEDICINAL PLANT BIOTECHNOLOGY UNIT 5, MPG, SEM 2 FERMENTATION TECHNOLOGY.pptxPrithivirajan Senthilkumar
This document discusses fermentation technology and its applications in biotechnology. It describes how fermentation is used to produce various industrial products like metabolites, biomass, recombinant proteins, and modified compounds. Specific examples of products discussed include single-cell proteins from microbes, ergot alkaloids from fungi, and enzymes of pharmaceutical interest. The stages of fermentation for production of ergot alkaloids and enzymes are also summarized.Recent advances in marine drugs
Marine natural products are drugs obtained from marine organisms that have been studied since ancient times. The oceans cover most of the earth's surface and are home to a vast diversity of species, many of which are still unknown. Marine organisms produce unique biochemical adaptations for survival in extreme conditions that could provide benefits for pharmacology. However, issues like limited supply, taxonomic identification challenges, and screening large numbers of microbes associated with invertebrates present obstacles for drug development from marine sources. Improved genetic engineering, databases, and activity-based screening methods may help address these problems and unlock the potential of marine organisms for new pharmaceuticals.
Marine natural products
As per the m. Pharmacy 1st year syllabus, this presentation includes all the information about "Marine natural products" such as detailed introduction, classification of marine drugs, general method of isolation and purification, detailed introduction and use of marine toxins. The source or reference of books/auther are included in last slide.
Drug discovery and development
The document discusses drug discovery and development. It begins with definitions of key terms like drug, drug discovery process, and drug development process. It then describes the main stages of new drug development, including drug discovery, preclinical development, and clinical development. Specific examples of discovered drugs are provided, such as artemisinin from Artemisia annua used to treat malaria, and andrographolide from Andrographis paniculata which has anti-inflammatory properties. The biosynthesis process of andrographolide is also summarized. In conclusion, the document provides an overview of the drug discovery and development process from target identification to clinical trials.
COSMECEUTICAL OF HERBAL AND NATURAL ORIGIN
This document discusses cosmeceuticals of herbal and natural origin. It defines cosmeceuticals as cosmetic products with bioactive ingredients that have medical benefits. Herbal cosmeceuticals use plant extracts to treat skin issues. Some advantages of herbal cosmetics over synthetic include being natural, safe, suitable for all skin types, and having no side effects. The document also discusses hair growth formulations using various herbal ingredients and evaluating their effects on hair growth in rats. Formulations for fairness creams using plant extracts like Glycyrrhiza glabra are also presented.
Extraction
The conventional method of extraction, a recent advanced method of extraction, choice of solvents, successive and exhaustive extraction.
Strychnine PPT.pptx
Strychnine is a toxic alkaloid found in the seeds of Strychnos nux-vomica. It acts as a central nervous system stimulant that binds to glycine receptors in the spinal cord, causing muscle contractions and ultimately death by asphyxiation. While highly toxic, strychnine was historically used as a pesticide for rodents and insects. Today its only minor medicinal use is as a stimulant and appetite enhancer in very small doses. The document provides details on the source, isolation, chemical properties, identification tests, derivatives and toxicity of strychnine.
monographs of herbal drugs I.P, U.S.P, A.H.P, B.P..pptx
This document provides a summary of monographs from various pharmacopoeias including the Indian Pharmacopoeia (IP), United States Pharmacopeia (USP), American Herbal Pharmacopoeia (AHP), and British Pharmacopoeia (BP). It defines what a pharmacopoeia and monograph are, and describes the typical format and components of monographs from each pharmacopoeia. Examples of monographs for ashwagandha from IP and banaba leaf from USP are also provided to illustrate the monograph formats.
CRUDE_DRUG_EVALUATION_1.pptx for the love of crude drugs
This document discusses the evaluation of crude drugs. Crude drugs are unrefined substances derived from plants, animals, or other organic sources that are used for medicinal purposes. Crude drugs must be evaluated to ensure proper identification, quality, and purity due to potential biochemical variations, deterioration over time or during storage, and risk of substitution or adulteration. The key methods used to evaluate crude drugs are organoleptic, microscopic, physical, chemical, and biological evaluations. Physical evaluation involves determining various physical characteristics and parameters of crude drugs such as moisture content, ash value, and extractive values. Maintaining appropriate moisture content is important to prevent microbial growth or chemical changes in crude drugs.
More Related Content
What's hot
Steroids Hecogenin.pptx
This topic covers the notes for unit 1 of phytochemistry in 1st semester in M Pharm of department of pharmacognosy. This includes biosynthesis, characterization, purification and uses of steroids.
Analytical profile of herbal drug.pptx
The document describes Andrographis paniculata, its extraction process, chemical constituents, and products. It discusses the extraction of andrographolide from the herb and describes the final products - andrographis paniculata dry extract and andrographolide. It also provides identification tests and specifications for these products.
Regulatory Asspects
Establishing a herbal drug industry requires navigating complex regulatory requirements related to safety, efficacy, quality and public health. Key aspects include complying with Good Manufacturing Practices, obtaining product licenses by submitting data on safety and efficacy to regulatory authorities, adhering to labeling and packaging guidelines, implementing quality control testing, monitoring adverse events, and ensuring compliance with international standards such as those of the International Conference on Harmonisation. Meeting these regulatory standards contributes to the success, credibility and public health impact of the herbal drug industry.
Phytopharmaceuticals- Durgashree Diwakar
A purified and standardized fraction with a defined minimum of four bioactive or phytochemical compounds of an extract of a medicinal plant or its part, for internal or external use of human beings or animals for diagnosis, treatment, mitigation, or prevention of any diseases but does not include administration by parenteral route.
Coumarin & Terpenoids
Biosynthesis, Isolation, Characterization, Purification, Structure Identification & Uses of
Coumarins :- Umbelliferone
Terpenoids :- Cucurbitacin
Health drinks by Nabarun Mukhopadhyay
This document discusses several natural health drinks including acai berry juice, green tea, goji berry juice, noni fruit juice, amla juice, and wheatgrass juice. It describes the source and botanical information for each drink, provides their nutritional composition, and lists their various health benefits such as increased energy, improved immune function, antioxidant effects, and more. The document concludes by citing several references for further information on the health impacts of these natural beverages.
MARINE NATURAL PRODUCTS P.P.T..ppsx
The document presents information on marine natural products. It discusses how marine organisms like algae, sponges and corals produce biologically active compounds with properties like anti-cancer, anti-inflammatory and antimicrobial effects. It describes methods used to isolate and purify compounds from marine sources, as well as challenges in marine drug research like taxonomic identification and chemical screening. Recent advances in marine drugs for conditions like cancer, inflammation and infections are also summarized. Finally, it briefly discusses marine toxins produced by some marine species that can cause illnesses in humans.
Drug discovery and Devlp- Durgashree Diwakar
Drug discovery is the process through which potential new medicines are identified.
It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology.
Natural products and their structural analogues have historically made a major contribution to pharmacotherapy, especially for cancer and infectious diseases.
Natural products also have challenges for drug discovery, such as technical barriers to screening, isolation, characterization and optimization.
Analytical profiling of herbal drugs
analytical profiling (HPTLC, HPLC and UV spectroscopy) of Curcuma lomga, Embelica officinalis and Psoralea Corylifolia
Extraction, isolation & estimation of ephedrine
This document describes the extraction, isolation, and estimation of ephedrine from Ephedra gerardiana and other Ephedra species. It involves powdering the dried stems and extracting with petroleum ether and aqueous alcohol. The extract is made alkaline and filtered to obtain a dry ephedrine residue. Estimation of ephedrine involves thin layer chromatography and high performance thin layer chromatography with solvent systems and visualization with ninhydrin reagent. Ephedrine content was estimated to be a maximum of 2.60% using a calibration curve. Ephedrine is used as a bronchodilator for asthma and to treat low blood pressure, with oral and parenteral doses provided.
Recent Advances in Extraction
Extraction of Phytochemicals
recent advances in extraction
Choice of solvent
Selection of method
Successive and exhaustive extraction
Nutraceuticals (Durgashree).pptx
The document discusses various types of nutraceuticals, including inorganic mineral supplements like calcium, magnesium, and zinc; vitamin supplements; digestive enzymes; dietary fibers; cereals and grains; antioxidants; polyunsaturated fatty acids; health drinks from natural sources like fruits, tea, and soy; and wines. It provides examples and health benefits of each category in 1-3 sentences and covers a wide range of nutraceutical topics over 12 pages.
Plants drug cultivation(Pharmacognosy)
Plants Drug Cultivation:
General introduction to importance pharmacognosy.
Indian Council of Agricultural Research.
Current good agricultural practices.
Current good cultivation practices
Current good collection practices.
Conservation of medicinal plants-Ex-situ & In-situ conservation of medicinal plants.
MEDICINAL PLANT BIOTECHNOLOGY UNIT 5, MPG, SEM 2 FERMENTATION TECHNOLOGY.pptx
MEDICINAL PLANT BIOTECHNOLOGY UNIT 5, MPG, SEM 2 FERMENTATION TECHNOLOGY.pptxPrithivirajan Senthilkumar
This document discusses fermentation technology and its applications in biotechnology. It describes how fermentation is used to produce various industrial products like metabolites, biomass, recombinant proteins, and modified compounds. Specific examples of products discussed include single-cell proteins from microbes, ergot alkaloids from fungi, and enzymes of pharmaceutical interest. The stages of fermentation for production of ergot alkaloids and enzymes are also summarized.Recent advances in marine drugs
Marine natural products are drugs obtained from marine organisms that have been studied since ancient times. The oceans cover most of the earth's surface and are home to a vast diversity of species, many of which are still unknown. Marine organisms produce unique biochemical adaptations for survival in extreme conditions that could provide benefits for pharmacology. However, issues like limited supply, taxonomic identification challenges, and screening large numbers of microbes associated with invertebrates present obstacles for drug development from marine sources. Improved genetic engineering, databases, and activity-based screening methods may help address these problems and unlock the potential of marine organisms for new pharmaceuticals.
Marine natural products
As per the m. Pharmacy 1st year syllabus, this presentation includes all the information about "Marine natural products" such as detailed introduction, classification of marine drugs, general method of isolation and purification, detailed introduction and use of marine toxins. The source or reference of books/auther are included in last slide.
Drug discovery and development
The document discusses drug discovery and development. It begins with definitions of key terms like drug, drug discovery process, and drug development process. It then describes the main stages of new drug development, including drug discovery, preclinical development, and clinical development. Specific examples of discovered drugs are provided, such as artemisinin from Artemisia annua used to treat malaria, and andrographolide from Andrographis paniculata which has anti-inflammatory properties. The biosynthesis process of andrographolide is also summarized. In conclusion, the document provides an overview of the drug discovery and development process from target identification to clinical trials.
COSMECEUTICAL OF HERBAL AND NATURAL ORIGIN
This document discusses cosmeceuticals of herbal and natural origin. It defines cosmeceuticals as cosmetic products with bioactive ingredients that have medical benefits. Herbal cosmeceuticals use plant extracts to treat skin issues. Some advantages of herbal cosmetics over synthetic include being natural, safe, suitable for all skin types, and having no side effects. The document also discusses hair growth formulations using various herbal ingredients and evaluating their effects on hair growth in rats. Formulations for fairness creams using plant extracts like Glycyrrhiza glabra are also presented.
Extraction
The conventional method of extraction, a recent advanced method of extraction, choice of solvents, successive and exhaustive extraction.
Strychnine PPT.pptx
Strychnine is a toxic alkaloid found in the seeds of Strychnos nux-vomica. It acts as a central nervous system stimulant that binds to glycine receptors in the spinal cord, causing muscle contractions and ultimately death by asphyxiation. While highly toxic, strychnine was historically used as a pesticide for rodents and insects. Today its only minor medicinal use is as a stimulant and appetite enhancer in very small doses. The document provides details on the source, isolation, chemical properties, identification tests, derivatives and toxicity of strychnine.
What's hot (20)
MEDICINAL PLANT BIOTECHNOLOGY UNIT 5, MPG, SEM 2 FERMENTATION TECHNOLOGY.pptx
MEDICINAL PLANT BIOTECHNOLOGY UNIT 5, MPG, SEM 2 FERMENTATION TECHNOLOGY.pptx
Similar to Terpenoids Cucurbitacin.pptx
monographs of herbal drugs I.P, U.S.P, A.H.P, B.P..pptx
This document provides a summary of monographs from various pharmacopoeias including the Indian Pharmacopoeia (IP), United States Pharmacopeia (USP), American Herbal Pharmacopoeia (AHP), and British Pharmacopoeia (BP). It defines what a pharmacopoeia and monograph are, and describes the typical format and components of monographs from each pharmacopoeia. Examples of monographs for ashwagandha from IP and banaba leaf from USP are also provided to illustrate the monograph formats.
CRUDE_DRUG_EVALUATION_1.pptx for the love of crude drugs
This document discusses the evaluation of crude drugs. Crude drugs are unrefined substances derived from plants, animals, or other organic sources that are used for medicinal purposes. Crude drugs must be evaluated to ensure proper identification, quality, and purity due to potential biochemical variations, deterioration over time or during storage, and risk of substitution or adulteration. The key methods used to evaluate crude drugs are organoleptic, microscopic, physical, chemical, and biological evaluations. Physical evaluation involves determining various physical characteristics and parameters of crude drugs such as moisture content, ash value, and extractive values. Maintaining appropriate moisture content is important to prevent microbial growth or chemical changes in crude drugs.
Introduction and scope of pharmacognosy by Dr.U.Srinivasa, Professor, Sriniv...
Introduction and scope of pharmacognosy by Dr.U.Srinivasa, Professor, Sriniv...Srinivas college of pharmacy, Mangalore
This document discusses the science of pharmacy and pharmacognosy. It defines pharmacy as dealing with the procurement, testing, storage, and conversion of drugs into suitable forms. Pharmacognosy is defined as the study of drugs from biological origins, including plants, animals, and minerals. The document outlines the scope of pharmacognosy, including isolation of phytochemicals, structure-activity relationships, cultivation of medicinal plants, and development of herbal formulations. Physical and chemical parameters used to evaluate crude drugs are also summarized, such as ash values, swelling factor, and extractive values.Biosynthetic Pathway for Terpenoids and Coumarins.pptx
1. Terpenoids
Introduction
Therapeutic Properties
Classification
Biosynthesis
Details of Cucurbitacin
2. Coumarins
Introduction
Details of Umbelliferon
Standardisation of hd by pooja
The document discusses guidelines for standardization and quality control of herbal drugs and formulations. It describes various parameters for standardization including macroscopic, microscopic, physical, chemical and biological evaluations. Specific tests covered include determination of foreign matter, ash values, extractive values, water soluble ash, total solid content, water content, volatile oil content, bitterness value, haemolytic activity, tannin content, swelling index and foaming index. Standardization helps in confirmation of identity, quality and purity of herbal drugs.
Standardisation of herbal drg
This document discusses guidelines for standardizing herbal drugs and herbal formulations. It provides details on various parameters for standardization including macroscopic, microscopic, physical, chemical and biological studies. Some key points covered are methods for determining moisture content, extractive values, ash values, volatile oil content, and biological activities like bitterness value, haemolytic activity and tannin content. The document emphasizes the importance of quality control and standardization of herbal drugs and formulations to ensure identity, purity and consistency in their composition.
CURCUMIN (Curcuma longa)
Turmeric is obtained from the dried rhizomes of the plant Curcuma longa. It contains the yellow chemical curcumin, which makes up 50-60% of turmeric. Curcumin can be isolated from turmeric powder through extraction with alcohol or hexane followed by acetone. Curcumin is identified through chemical tests where it produces a crimson color with sulfuric acid or a reddish brown color with boric acid that turns greenish blue with alkali. Curcumin content can be analyzed using methods like HPLC, where it shows peaks at specific retention times when separated using a Nucleosil NH2 column with ethanol mobile phase and UV detection at 254nm.
ANTI-MICROBIAL ACTIVITY OF DIGESTIVE CHURNA
This presentation helps to know about the particular media and churna prepared and its anti-microbial activity. This also provides results obtained after testing.
important methods employed in quality control of ayurvedic drugs
the different methods employed these days to test the quality of ayurvedic drugs is summarised in the presentation. the presentation aims to give an awareness about basic procedures in quality control of ayurvedic drugs.
Antitumor diabetics diuretics.pdf
In this section, you will learn about agents showing anti tumor, antidiabetic and diuretic properties like vinca, podophyllum, gokhru, punarnava etc.
This material is applicable for both diploma and bachelor in pharmacy.
3. pharmaceutical aid
Pharmaceutical aids are inert substances that have little to no pharmacological effect but are essential in the preparation of pharmaceutical dosage forms. This document discusses various categories of pharmaceutical aids including organoleptic aids like colouring agents, flavouring agents, and sweetening agents that improve the appearance and taste of medications. It also covers preservatives that are added to formulations to prevent microbial growth and degradation during storage. Common organoleptic and preservative aids used in pharmaceutical products are described along with their properties and uses.
WHO_ppt_final - Copy.ppt
The document discusses guidelines for standardization of herbal products as outlined by the World Health Organization (WHO). It defines herbal drugs and discusses their use as over-the-counter products, dietary supplements, and herbal medicines. The document outlines various quality evaluation tests for herbal drugs, including macroscopic and microscopic analysis, physicochemical properties like ash value and extractive tests, and microbial, toxicological and radioactive contamination limits. It emphasizes the need for quality control and standardization of herbal drugs to ensure consumer safety.
The extraction, preparation and storage of medicinal.pptx
The extraction, preparation and storage of medicinal.pptxRedemption higher institutions of Biomedical and management sciences
This document discusses the extraction, preparation, and storage of medicinal plants for experimental purposes. It outlines various extraction methods like maceration, infusion, digestion, and decoction. Medicinal plants can be prepared into liquid dosage forms like fluid extracts, infusions, tinctures, and syrups or solid forms like powders and granules. Storage is important to maintain the plant's properties, but extracts can be affected by biological, physical and chemical factors over time. Proper extraction methods and storage conditions are recommended to ensure quality and quantity of plant extracts for experiments.Flavonoids
Flavonoids are plant secondary metabolites that are classified based on their chemical structure. They are abundant in many plant families and occur as both free compounds and glycosides. Key classes include flavonols, flavones, flavanones, isoflavones, and anthocyanidins. Flavonoids have a variety of biological effects and are found in several plants that are used medicinally such as orange peel, garcinia, soybean, liquorice, cranberry, and buckwheat.
Phytosome-WPS Office.pptx
The term "phyto" means plant and "some" means cell-like.Phytosomes are little cell like structures.
Structure of phytosome
Properties of phytosome - chemical and biological
Methods of preparation
SAKIRA SLIDE.pptx
This document summarizes an oral presentation on advances in essential oil extraction, encapsulation, and application. The presentation outlines introduction, extraction methods, factors for choosing extraction methods and solvents, identification and characterization of extracts, and conclusion. Various extraction techniques are discussed including maceration, percolation, Soxhlet extraction, and factors to consider like stability, solvent properties, and intended use. Identification requires separation techniques like chromatography followed by structure determination and activity assessment. In conclusion, selecting proper techniques at each step from extraction to identification is key to authentic results in medicinal plant research.
HOMEOPATHY.pptx
Here is some general information about the homeopathic system of medicine, including the types of drugs and dosage forms used, as well as the methods used to standardize formulations.
Standardization Herbal drug and Compound formulations/
Standardization of drug, ORGANOLEPTIC EVALUATION, MICROSCOPIC EXAMINATION,DETERMINATION OF FOREIGN MATTER, DETERMINATION OF ASH, DETERMINATION OF HEAVY METALS, MICROBIAL CONTAMINANTS, DETERMINATION OF PESTICIDE RESIDUES, DETERMINATION OF RADIOACTIVE CONTAMINATION, PHYTOCHEMICAL PROFILES- FINGERPRINTING, MULTIPLE MARKER- BASED FINGER PRINTING, Curcumin, Microbiology specification for species, Compound formulation, Herbal formulations, TRADITIONAL DOSAGE FORMS, MODERN HERBAL DOSAGE FORMS, NOVEL DRUG DELIVERY STEMS (NDDS)/ NOVEL DOSAGE SYSTEM, SYRUP, MIXTURE, TABLET, LIPOSOME, Curcumin,
NIOSOMES, PRONIOSOMES, NANOPARTICLES, ETHOSOMES, MARKETED HERBAL NOVEL DRUG DELIVERY FORMULATIONS,
Curcumin Longa-L.pptx
Curcumin:Extraction of Curcumin Paper &Thin layer Chromatography, Antibacterial Activity of Curcumin
Plan of work
Introduction
Extraction of curcumin
Chromatography
Conclusion
Herbal drug
This presentation will give you the information about the standardization and preservation of herbal drug
It will also predict the information about the drawbacks or false of which we will get while in the synthesis of drug
Similar to Terpenoids Cucurbitacin.pptx (20)
monographs of herbal drugs I.P, U.S.P, A.H.P, B.P..pptx
monographs of herbal drugs I.P, U.S.P, A.H.P, B.P..pptx
CRUDE_DRUG_EVALUATION_1.pptx for the love of crude drugs
CRUDE_DRUG_EVALUATION_1.pptx for the love of crude drugs
Introduction and scope of pharmacognosy by Dr.U.Srinivasa, Professor, Sriniv...
Introduction and scope of pharmacognosy by Dr.U.Srinivasa, Professor, Sriniv...
Biosynthetic Pathway for Terpenoids and Coumarins.pptx
Biosynthetic Pathway for Terpenoids and Coumarins.pptx
important methods employed in quality control of ayurvedic drugs
important methods employed in quality control of ayurvedic drugs
The extraction, preparation and storage of medicinal.pptx
The extraction, preparation and storage of medicinal.pptx
Standardization Herbal drug and Compound formulations/
Standardization Herbal drug and Compound formulations/
More from Shruti Salve
Indian Systems of Medicine Aromatherapy.pptx
Aromatherapy as the name itself indicates it involves the use of natural herb oils that are aromatic (have pleasant smell) for the treatment of pain or may be used for massage, it is said to be one of the oldest or ancient method of treatment and mitigation.
The Aromatherapy is based on the concept of Osphresiology.
Osphresiology is the study of physiology and other aspects of olfaction.
Olfaction is defined as the sense of smell that detects and differentiate between the smells.
Osphresiology is an inter-disciplinary science that involves molecular physics, as well as psychology.
Aromatherapy is not just limited to basics of olfaction.
The aromatic substances are found to have tremendous potential in treatment of :
Wounds, Skin acne problems, Arthritis, Stress.
The Aromatherapist not only selects how to initiate the treatment but also chooses the oils that are necessary in the treatment.
After the selection of specific oils for treatment the way of the treatments are decided.
The types of treatment in aromatherapy are as follows:
Massage by aromatic oils, essential oils
Inhalation of steam
Bath
Miscellaneous
1. Massage by Aromatic oils, Essential oils:
In massage technique the aromatherapist concentrates on massaging specific pressure points.
This massaging leads to working on lymph nodes(Part of WBC’s present in whole body).
The oils that are used during the massage are carefully selected from the diagnosis of the aromatherapist.
These oils thus work internally while the massage relaxes the body externally.
2. Inhalation :
6-8 drops of aromatic oil is required to be sprinkled on the tissue paper or clean cloth.
The inhalation can be done by sprinkling the drops of oils in hot water and inhaled for 10-15 minutes.
Inhalation technique is generally recommended for the patients that have problems relating to breathing, Asthmatic patients, disease of lungs.
3. Bath :
Baths can be for hand, foot, or for full body.
4-8 drops of essential oil / aromatic oil is recommended in bowl of warm water used for soaking arms or foots for 10 minutes.
In case of full body baths 5-10 drops of aroma oil are added to warm bath water and the whole body is immersed in it for 10-20 minutes.
Aromatherapy benefits:
1. Manage pain
2. Improves sleep quality
3. Reduces stress and anxiety
4. Soothe sore joints
5. Treat headache and migraines
6. Alleviate side effects of chemotherapy
7. Improves digestion
8. Boosts circulation
Commonly used Aroma oils and their details:
Lavender oil :
Best for: Stress relief, improves sleep, use in headache, refreshes mind.
Peppermint oil :
Best for: Reduces stress, improves mental function, reduces pain, Relieve IBS symptoms.
The carrier oil is simply defined as the base oil which is used to dilute an essential oil/ aromatic oil in the treatment of Aromatherapy.
The carrier oil is also known as base oil or vegetable oil.
Various examples of Carrier oils are :
Coconut oil
Black cumin seed oil
Jojoba oil
Evening Primrose oil
Herbal cosmetic Design of herbal formulation shruti.pptx
Herbal cosmetics are defined as the products which prepared by or included plants and/or herbal components which are combination of many natural molecules or compounds.
Alteration in pharmacological activity of one drug by the concomitant(drug having same action) use of another drug or other substances.
The concurrent use of herbs may increase or decrease or mimic the effect of other drugs.
Possibilities of interactions between chemicals and herbal products:
1.There is no direct chemical reaction between herb and drug but few components of herb may affect the effect of drugs.
2.Herbal drugs when taken with other synthetic preparation may show harmful and toxic effects on body.
3.The interactions may be due to presence of impurities present in excipients of the synthetic drugs or it can be due to impurities from natural source viz. Heavy metals, incorrect species etc.
Herbal drug interactions can affect health and efficiency of treatments.
Herbal drug interactions might lead to side effects. Interaction may lead to failure of formulation.
Unexpected effects may be observed after application of the cosmetic.
Types of drug-herb interactions as per Ayurveda:
1.Herb-Herb Interaction: Eg. Piper betal should not be administered with Garcinia Morella (Indian gamboge)
2.Herb-Food Interaction: Eg. Sesame seed with black cumin cause diarrhea.
3.Herb & drug of animal origin: Eg. Meat is contraindicated with Brassica alba (White mustard)
4.Interactions related to diseases: Eg. Haritaki cannot be administered in pregnancy.
Design of herbal cosmetic formulation is an important part in preparation of herbal cosmetics, it is done on the basis of type of the cosmetics according to the site of application as follows:
1.Skin
2.Hair
3.Dentifrice
4.Nails
5.Eyes
Herbal cosmetics for skin care are based on 3 important approaches/ Steps:
Cleanse (To clean).
a. Nourish (To take care)
b. Moisture (To keep skin
c. hydrated/ Prevent Dryness)
Herbal cosmetics are classified depending upon:
a. Type of the skin
b. Type of the cream
c. Type of the lotions
Herbal cosmetics classification depending upon Type of Cream:
Cold cream: It is Water-in-oil (W/O) type of emulsion which produces cooling effect after application.
Example: Cold cream containing Mentha oil, aloevera.
Vanishing cream: As the name itself indicates this type of cream vanishes after it is applied on the skin by rubbing. It is Oil-in-water (O/W) type of emulsion and are useful for removing make-ups.
Example: Vanishing creams containing Sweet almond oil.
Cleansing cream: It is Water in Oil (W/O) type of cream that melts over the body temperature and spreads easily over the skin.
Example: Cream containing chamomile flower
Herbal cosmetics classification depending upon Type of Lotion:
Face lotion: Also known as bleaching lotions which mask the face and produce brightening effects on the skin after washing.
Eg. Face lotion containing Almond and saffron.
Adulteration
Many herbal medicinal products have been found to contain synthetic prescription drugs as chemical adulterants.
This is become evident by the number of toxicity cases and adverse reactions reported in which casualties were reported via analytical techniques that detected the presence of chemical adulterants in them, which could be responsible for their toxicity.
The adulteration of herbal medicinal products with synthetic drugs continues to be a serious problem for regulatory agencies.
The quality control standards of various medicinal plants used in indigenous system of medicine are becoming more relevant today in view of commercialization of formulations based on medicinal plants.
For standardization and quality assurance purposes, following 3 attributes are desirable i) Authenticity, ii) Purity and iii) Assay.
Authenticity relates to proving that the material is true.
Authentication in itself involves many parameters including gross morphology, microscopy, chemical analysis and DNA fingerprinting.
Purity pertains to evaluating that there are no adulterants present in the plant material.
Assay part of standardization is chemical and biological profiling which could assess the chemical effects.
What is Adulteration?
Adulteration is a process/practice of substituting the original drug/herb with completely or partially similar looking substance.
The substance may be inferior in quality or may be therapeutically inactive.
What is Deterioration?
It is the process of degradation or destruction of herbs which leads to loss of therapeutic activity of the drug/herb.
Deterioration & Adulteration are inter-related and deterioration is the main effect of adulteration.
Adulteration is classified into 2 types:
Intentional Adulteration:
As the name itself indicates the intentional adulteration is the process where the substitution of drug/herb is done in full awareness this type of adulteration is commonly done by suppliers/manufacturers.
Un-intentional Adulteration:
This is the second type of adulteration where the substitution of drug/ herbs happens without the knowledge of manufacturer/supplier.
Reasons for Intentional adulteration:
1. Due to high prices of original herb/ drugs.
2. Due to lack of availability of the drug/herbs.
3. To earn more profits by substituting the herbs by the herb of lesser price.
Types of Intentional adulteration:
1. Substitution with inferior varieties.
2. Adulteration by artificially manufactured substance.
3. Usage of vegetative part of same plant.
4. Substitution with superficially similar but cheaper natural drug substance.
The presence of vegetative parts of the same plant with the drug in excessive amount is also an adulteration. For example, epiphytes, such as mosses, liverworts and lichens that grow over the barks also may occur in unusual amounts with the drugs, e.g. cascara or cinchona.
ICAR Indian Council of Agricultural Research.pptx
ICAR is an autonomous body responsible for agricultural education and research in India.
ICAR comes under the Department of Agricultural Research and Education (DARE), Ministry of Agriculture and Farmers Welfare, Government of India.
The ICAR has its headquarters at New Delhi.
The Council is responsible for co-ordinating, guiding and managing research and education in agriculture including horticulture, fisheries and animal sciences in the entire country.
The Indian Council of Agricultural Research (ICAR) is an autonomous body responsible for co-ordinating agricultural education and research in India. It reports to the Department of Agricultural Research and Education, Ministry of Agriculture.
The Union Minister of Agriculture serves as its president.
It is the largest network of agricultural research and education institutes in the world.
The committee to Advise on Renovation and Rejuvenation of Higher Education (Yashpal Committee, 2009) has recommended setting up of a constitutional body – the National Commission for Higher Education and Research – which would be a unified supreme body to regulate all branches of higher education including agricultural education.
Presently, regulation of agricultural education is the mandate of ICAR, Veterinary Council of India (Veterinary sub-discipline) and Indian Council of Forestry Research and Education (Forestry sub-discipline).
A number of natural resource management institutes of India also come under the ICAR.
The Indian Agricultural Research Institute (IARI), popularly known as Pusa Institute, began in 1905 at Pusa (Bihar).
The institute was then known as Agricultural Research Institute (ARI) which functioned with five departments, namely Agriculture, Cattle Breeding, Chemistry, Mycology and Bacteriology.
In 1919, it was renamed as Imperial Agricultural Research Institute.
The institute was shifted from Pusa (Bihar) to Delhi on 29th July 1936
Post independence, the institute has been renamed as Indian Agricultural Research Institute (IARI).
The Indian Agricultural Research Institute (IARI), New Delhi, played a great role in Green Revolution and Human Resource Management.
IARI continues its efforts to bring Evergreen Revolution for sustainable food and nutrition of the country.
Nutraceutical drugs.pptx
Nutraceutical is any substance that is a food or a part of food and provides medical or health benefits.
The term “nutraceutical” is used to describe these medicinally or nutritionally functional foods.
Nutraceuticals, which have also been called medical foods, designer foods, phytochemicals, functional foods and nutritional supplements, include such everyday products as “bio” yoghurts and fortified breakfast cereals, as well as vitamins, herbal remedies and even genetically modified foods and supplements. Many different terms and definitions are used in different countries, which can result in confusion.
The term “nutraceutical” was coined in 1989 by Stephen De Felice, founder and chairman of the Foundation for Innovation in Medicine, an American organization which encourages medical health research.
He defined a nutraceutical as a “food, or parts of a food, that provide medical or health benefits, including the prevention and treatment of disease”.
Cyanobacteria are aquatic and phytosynthetic organisms known for their rich contents of proteins.
Spirulina (arthrospira) shows anticancer and antimicrobial (antibacterial, antifungal and antiviral) activities via the production of phycocyanin, phycocyanobilin, allophycocyanin and other valuable products.
Spirulina can lower triglycerides, LDL Cholesterol and sometimes may raise HDL Cholesterol.
Spirulina may have some anti-cancer properties, especially against a type of precancerous lesions of the mouth.
Soybean is most important edible plant known for its seeds as a source of protein, oil and nutraceuticals.
It contains essential amino acids and secondary metabolites such as isoflavaone, saponins, phytic acid, phytosterol.
The presence of folic acid is an additional attraction, since the deficiency of this nutrient is a serious concern globally.
Soya beans contain essential minerals like Copper and Iron that aid in RBC production. Due to its high dietary fibers, protein and low sugar amounts soya bean helps in controlling blood sugars and managing diabetes.
Adding soya bean to your diet may help relieve you from prolonged episodes of insomnia as it contains Magnesium.
Ginseng, as dietary supplement, plays a key role in disease prevention by modulating the immune function of human body.
Extracts and bioactive compounds isolated from ginseng are studied for their various health promoting activities like antioxidant, antitumor, anti-hyperglycemic, skin protecting, anti-osteoporotic, anticancer, anti-infective and respiratory problems.
Ginseng extracts and ginsenoside compounds from ginseng has beneficial antioxidant and anti-inflammatory properties.
It possesses potent antibacterial, antifungal and antiviral properties and may enhance the function of the immune system. Ginseng could help improve brain functions like memory, behavior and mood.
GLP and ISO 9000.pptx
Concepts of GLP and ISO 9000. The Good Laboratory Practices Guideline (GLP) is an FDA regulation. Good Laboratory Practices (GLP) embodies a set of principles that provides a framework within which laboratory studies are planned, performed, monitored, recorded and reported. National Good Laboratory Practice (GLP) Compliance Monitoring Authority (NGCMA). NGCMA was established by the Department of Science & Technology (DST), Government of India, with the approval of the Union Cabinet on April 24, 2002.
ISO 9000 is a series of standards, developed and published by the International Organization for Standardization (ISO), which is an independent, non-governmental organization made up of members from over 160 countries.
The ISO 9000 family of standards is related to Quality Management Systems and designed to help organizations ensure that they meet the needs of customers and other stakeholders while meeting statutory and regulatory requirements. ISO 9000 deals with the fundamentals of quality management systems, including the 7 Quality Management Principles on which the family of standards is based.
Glycoside
Glycyrrhizin is a major glycoside extracted from the roots of the liquorice plant (Glycyrrhiza glabra). It has a molecular formula of C42H62O16 and molecular weight of 822.94 gm/mol. Glycyrrhizin is 30-50 times sweeter than sucrose and can be isolated from liquorice roots using alcohol or ammonia extraction methods due to its solubility properties. It has a variety of medicinal uses and is estimated quantitatively using techniques like TLC-densitometry, colorimetric assays, and HPLC.
Clove medicinal uses
Clove (Syzygium aromaticum) is medicinally powerful herb. Cloves are also known as Clovos, Lavang, Laung. In india, cloves are grown in Nilgiries, Tensaki Hills of Tamil Nadu state, Kottayam and Kollam district of kerala. It holds several phytochemicals. Major phytochemicals includes Eugenol, Eugenyl acetate and Beta-caryophyllene. Clove contains essential oils in its buds, leaves, stem and fruits. Clove owns major pharmacological activities like antioxidant, antimicrobial, anti-inflammatory, anticarcinogenic, antibacterial, antipyretic and analgesic, etc.
More from Shruti Salve (8)
Herbal cosmetic Design of herbal formulation shruti.pptx
Herbal cosmetic Design of herbal formulation shruti.pptx
Recently uploaded
Adhd Medication Shortage Uk - trinexpharmacy.com
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Novas diretrizes da OMS para os cuidados perinatais de mais qualidade
Novas diretrizes da OMS para os cuidados perinatais de mais qualidadeProf. Marcus Renato de Carvalho
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Histololgy of Female Reproductive System.pptx
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
REGULATION FOR COMBINATION PRODUCTS AND MEDICAL DEVICES.pptx
It includes regulation of combination products and medical devices. FDA and industry liaisons.
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Top 10 Best Ayurvedic Kidney Stone Syrups in India
we have mentioned the best 10 ayurvedic Kidney Stone Syrups. You can check all these products and choose the best one for yourself.
Best Ayurvedic medicine for Gas and Indigestion
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Top Effective Soaps for Fungal Skin Infections in India
Swisschem Dermacare has mentioned the List of The Best Antifungal Soap In India 2022. All of these soaps are trusted by various Dermatology Experts.
Journal Article Review on Rasamanikya
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Efficacy of Avartana Sneha in Ayurveda
Avartana Sneha is a unique method of Preparation of Sneha Kalpana in Ayurveda, mainly it is indicated for the Vataja rogas.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
share - Lions, tigers, AI and health misinformation, oh my!.pptx
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Recently uploaded (20)
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
Novas diretrizes da OMS para os cuidados perinatais de mais qualidade
Novas diretrizes da OMS para os cuidados perinatais de mais qualidade
REGULATION FOR COMBINATION PRODUCTS AND MEDICAL DEVICES.pptx
REGULATION FOR COMBINATION PRODUCTS AND MEDICAL DEVICES.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis - Definition , Evaluation and Management .pdf
Top 10 Best Ayurvedic Kidney Stone Syrups in India
Top 10 Best Ayurvedic Kidney Stone Syrups in India
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
share - Lions, tigers, AI and health misinformation, oh my!.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptx
Terpenoids Cucurbitacin.pptx
- 1. TERPENOIDS : CUCURBITACIN A Seminar on SUBMITTED TO : Miss B. R. Gupta Dept. of Pharmacognosy PRESENTED BY : Miss S. A. Salve 1st Year M.Pharmacy Dept of Pharmacognosy Department of Pharmacognosy MGV’s Pharmacy College, Panchavati, Nashik
- 2. CONTENTS • Introduction • Characterization • Biosynthesis • Isolation • Purification • Medicinal Uses • References
- 3. INTRODUCTION What is TERPENOIDS? • The terpenoids sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenoids. • Terpenoids are hydrocarbons of plant origin of the general formula (C5H8)n as well as their originated, hydrogen and dehydrogenated derivatives. • Plant terpenoids are used for their aromatic qualities and play a role in traditional herbals remedies.
- 4. CHARACTERIZATION • Terpenoids are colourless liquids. • Soluble in organic solvent and insoluble in water. • Volatile in nature • Boiling Point is around 150-180°C • They are unsaturated compound. • Basically it contain isoprene unit in chemical structure.
- 5. CUCURBITACIN
- 6. INTRODUCTION • Cucurbitacin is a bitter-tasting principle that can be isolated from members of family Cucurbitaceae, such as cucumber (Cucumis sativus) and melon (Cucumis melo). • In particular, cucurbitacin and momordicine, which have an intensly bitter taste, are content abundantly in Momordica charantia. • There are more than 18 kinds of cucurbitacin and among them cucurbitacin B is a typical component.
- 7. DIFFERENT SOURCES OF CUCURBITACIN Memordica Melon Pumpkin Cucumber
- 10. ISOLATION Cucurbitacin containing plant material Pressing Liquid containing cucurbitacin Extracted with non- polar solvent like chloroform to remove the waxes, pigments, fatty acids terpenes Separated liquid is then extracted with moderately polar solvent like water Separation of cucurbitacin Collection of cucurbitacin
- 11. PURIFICATION Purification can be done by using: 1. Flash Chromatography 2. Column Chromatography 3. Paper Chromatography Structure identify by following methods : • By UV spectroscopy • By IR spectroscopy • By MASS spectroscopy • By NMR spectroscopy
- 12. CHARACTERIZATION • Taste : Bitter • Color : Yellowish • Molecular Formula : C32H44O8 • Molecular weight : 556.696 g/mol • Chemical structure of cucurbitacin :
- 13. MEDICINAL USES • Anti inflammatory • Anti tumor • Anti diabetic • Anti artherosclerotic • Anti oxidant activity • Hepatoprotective • Anti epileptic • Anxiolytic • Antifungal • Analgesic
- 14. REFERENCES 1. Ujjwal Kaushik, Vidhu Aeri, Showkat R. Mir, Cucurbitacin – An insight into medical leads from nature, January-June 2015, Volume 9, Issue 17, Page no. 12-18 2. Dr. Abdullah A. Alghasham, Cucurbitacin – A Promising Target for Cancer Therapy, International Journal of Health Sciences (Qassim University) 2013 Jan; Volume 7(1), Page no. 77-89 3. Ashmi Samual, Cucurbitacins and its Anticancer property: A Review, Himalayan Journal of Health Sciences, Volume 4, Issue 4; Oct – Dec 2019