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Universidad Autónoma de Nuevo León 
Facultad de Ciencias Biológicas 
Licenciado en Biotecnología Genómica 
Primer semestre Grupo 413 
Bioética – Dr. Carlos Jair Guerrero-García 
• Martín Bernal López 1543619 
• Eloisa Garza González 1636948 
• Jennifer Ainara Godínez Pérez 1717821 
• Celeste F. Gracia Rodríguez 1717817 
• Erick Irving Hernández Villarreal 1634301
Agenda 
• Abstract 
• Bioingeniería 
• Biología sintética 
• Biobricks 
• Riesgos y beneficios
El ensayo fue escrito por Zachary 
Russ estudiante de primer año 
cursando la Carrera de Bioingeniería 
en la Universidad de Maryland.
Un bioingeniero es quién se ocupa de todos los 
aspectos tecnológicos relacionados de alguna 
manera en la medicina y la biología. Además, al 
igual que un biólogo o un médico, se encarga del 
estudio y el análisis de todos los organismos vivos.
- Nobel Laureate and physicist Richard P. Feynman 
La bioingeniería aún y con todos sus logros tiene que 
crear vida para encajar en el mismo tipo de precisas 
especificaciones que los ingenieros químicos tienen que 
hacer con moléculas y que los ingenieros mecánicos 
tienen con lasmáquinas.
“The newly introduced field of synthetic biology 
(synbio) represents a response to that problem.” 
¿QUÉ ES?
La base de la Biología Sintética son los biobricks, fragmentos 
de ADN que codifican para una característica biológica y que 
pueden ser combinados para formar circuitos complejos. 
Los biobricks constituyen, por tanto, la unidad estándar y 
modular básica que realiza una función simple y permiten 
modificar el comportamiento de una célula sin la 
necesidad de conocer a priori el funcionamiento exacto 
del sistema. http://syntheticbiology.org/BioBricks.html
The BioBricks project takes the former approach, and, by 
designing organisms using standardized building blocks, makes 
genetic engineering easier and much more efficient. BioBricks 
provide the potential to make biochemicals and pharmaceuticals 
quickly and easily without having to worry about unforeseen 
interactions between the drug genes and vestigial genes
With complete control over the genomes of their organisms, synbioengineers 
can introduce specific weaknesses into their organisms, such as a 
dependency on a particular amino acid, so that lab experiments have little 
chance of surviving in the wild. Without the noise data that natural 
organisms have in their genomes, synthetic organisms will also be very 
limited in genetic variation and virtually unable to adapt to new conditions.
While accidental harm is significant, in the 
age of terrorism in which we live, malice is 
also an important factor in technologies. 
There is even more risk to not using synthetic 
biology. Synthetic biology can produce organisms 
to clean up pollution and provide clean energy. 
Proteins and food can be created without wasting 
energy on a full-sized organism, providing cheap 
ways to make nutritious meals for millions. 
Synbio is the opportunity to gain power over life 
and achieve the ultimate goal in engineering – to 
be so familiar with a part that its behavior can be 
modeled, predicted, and used; and the uses are 
limitless
“The genetic code is 3.6 billion years old. It's time for a rewrite.”
1.Chan LY, Kosuri S, Endy D: "Refactoring bacteriophage T7".[http://www.nature.com/msb/journal/v1/n1/full/msb4100025.html] webcite 
Molecular Systems Biology 2005, 
2. Bunting M: Scientists have a new way to reshape nature, but none can predict the cost. [http://www.guardian.co.uk/comment/story/0,,2196332,00.html] webciteThe 
Guardian October 22, 2007 
3.BioBricks Foundation[http://www.biobricks.org/] webcite 
Retrieved October 26, 2007 
4.Hale V, Keasling JD, Renninger N, Diagana TT: "Microbially Derived Artemisinin: A Biotechnology Solution to the Global Problem of Access to Affordable 
Antimalarial Drugs". [http:/ / www.ajtmh.org/ cgi/ content/ full/ 77/ 6_Suppl/ 198?maxtoshow=&HITS=10&hits=10&RESU LTFORMAT=&author1=Keasling&searchid 
=1&FIRSTINDEX=0&sortspec=relevance& resourcetype=HWCIT] webcite 
Am J Trop Med Hyg 2007, 77:198-202. PubMed Abstract | Publisher Full Text 
5.Silver LM: Life 2.0. Newsweek International. [http:/ / wws-silvermacg4.princeton.edu/ challenging/ articles/ 2007Newsweek/ Scientists.html] webcite 
June 4, 2007 
6. http://www.grain.org/es/article/entries/1103-biologia-sintetica-el-futuro-de-la-vida-en-manos-de-los-cientificos 
7. http://microbioun.blogspot.mx/2014/03/biologia-sintetica-para-que-construir.html 
8. http://www.elmundo.es/ciencia/2014/05/07/536a6edae2704e7f278b4584.html

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Synthetic biology

  • 1.
  • 2. Universidad Autónoma de Nuevo León Facultad de Ciencias Biológicas Licenciado en Biotecnología Genómica Primer semestre Grupo 413 Bioética – Dr. Carlos Jair Guerrero-García • Martín Bernal López 1543619 • Eloisa Garza González 1636948 • Jennifer Ainara Godínez Pérez 1717821 • Celeste F. Gracia Rodríguez 1717817 • Erick Irving Hernández Villarreal 1634301
  • 3. Agenda • Abstract • Bioingeniería • Biología sintética • Biobricks • Riesgos y beneficios
  • 4. El ensayo fue escrito por Zachary Russ estudiante de primer año cursando la Carrera de Bioingeniería en la Universidad de Maryland.
  • 5. Un bioingeniero es quién se ocupa de todos los aspectos tecnológicos relacionados de alguna manera en la medicina y la biología. Además, al igual que un biólogo o un médico, se encarga del estudio y el análisis de todos los organismos vivos.
  • 6. - Nobel Laureate and physicist Richard P. Feynman La bioingeniería aún y con todos sus logros tiene que crear vida para encajar en el mismo tipo de precisas especificaciones que los ingenieros químicos tienen que hacer con moléculas y que los ingenieros mecánicos tienen con lasmáquinas.
  • 7. “The newly introduced field of synthetic biology (synbio) represents a response to that problem.” ¿QUÉ ES?
  • 8. La base de la Biología Sintética son los biobricks, fragmentos de ADN que codifican para una característica biológica y que pueden ser combinados para formar circuitos complejos. Los biobricks constituyen, por tanto, la unidad estándar y modular básica que realiza una función simple y permiten modificar el comportamiento de una célula sin la necesidad de conocer a priori el funcionamiento exacto del sistema. http://syntheticbiology.org/BioBricks.html
  • 9. The BioBricks project takes the former approach, and, by designing organisms using standardized building blocks, makes genetic engineering easier and much more efficient. BioBricks provide the potential to make biochemicals and pharmaceuticals quickly and easily without having to worry about unforeseen interactions between the drug genes and vestigial genes
  • 10. With complete control over the genomes of their organisms, synbioengineers can introduce specific weaknesses into their organisms, such as a dependency on a particular amino acid, so that lab experiments have little chance of surviving in the wild. Without the noise data that natural organisms have in their genomes, synthetic organisms will also be very limited in genetic variation and virtually unable to adapt to new conditions.
  • 11. While accidental harm is significant, in the age of terrorism in which we live, malice is also an important factor in technologies. There is even more risk to not using synthetic biology. Synthetic biology can produce organisms to clean up pollution and provide clean energy. Proteins and food can be created without wasting energy on a full-sized organism, providing cheap ways to make nutritious meals for millions. Synbio is the opportunity to gain power over life and achieve the ultimate goal in engineering – to be so familiar with a part that its behavior can be modeled, predicted, and used; and the uses are limitless
  • 12. “The genetic code is 3.6 billion years old. It's time for a rewrite.”
  • 13. 1.Chan LY, Kosuri S, Endy D: "Refactoring bacteriophage T7".[http://www.nature.com/msb/journal/v1/n1/full/msb4100025.html] webcite Molecular Systems Biology 2005, 2. Bunting M: Scientists have a new way to reshape nature, but none can predict the cost. [http://www.guardian.co.uk/comment/story/0,,2196332,00.html] webciteThe Guardian October 22, 2007 3.BioBricks Foundation[http://www.biobricks.org/] webcite Retrieved October 26, 2007 4.Hale V, Keasling JD, Renninger N, Diagana TT: "Microbially Derived Artemisinin: A Biotechnology Solution to the Global Problem of Access to Affordable Antimalarial Drugs". [http:/ / www.ajtmh.org/ cgi/ content/ full/ 77/ 6_Suppl/ 198?maxtoshow=&HITS=10&hits=10&RESU LTFORMAT=&author1=Keasling&searchid =1&FIRSTINDEX=0&sortspec=relevance& resourcetype=HWCIT] webcite Am J Trop Med Hyg 2007, 77:198-202. PubMed Abstract | Publisher Full Text 5.Silver LM: Life 2.0. Newsweek International. [http:/ / wws-silvermacg4.princeton.edu/ challenging/ articles/ 2007Newsweek/ Scientists.html] webcite June 4, 2007 6. http://www.grain.org/es/article/entries/1103-biologia-sintetica-el-futuro-de-la-vida-en-manos-de-los-cientificos 7. http://microbioun.blogspot.mx/2014/03/biologia-sintetica-para-que-construir.html 8. http://www.elmundo.es/ciencia/2014/05/07/536a6edae2704e7f278b4584.html