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Embryology is literally “the study of the embryo”. More generally it refers to “the study of prenatal development” Defination: ‘’The study of the process of growth and differentiation of the embryo, starting from fertilization of an ovum and progressing to a fully formed individual animal.’’ Although a mammalian body is made up of an array of organ system, tissues and individual cells which function in a highly coordinated manner but they are all derived from a single cell, fertilized ovum. Ontogeny : stages of development of an individual Teratology : study of abnormal development (congenital malformations) Developmental Stages Of Embryo: Fertilization Cleavage Gastrulation Organogenesis Maturation CELL CYCLE Cells associated with formation and regeneration are somatic cells and they divide through mitosis. Cells associated with reproduction are known as germ cells including male female gametes, they divide through meiosis. Somatic cells undergo a series of molecular and morphological changes as part of the cell cycle. The changes occur in four phases G1, S, G2, and M and also a quiescent Go phase. G1 and G2 phase are known as resting phases. The cells are metabolically active fulfilling its requirements for the next phase of cycle. In S phase DNA synthesis occurs before chromosomal replication. Collectively G1,S and G2 phase form the interphase which is the preparatory phase before mitotic phase. Certain fully differentiated cells such as neurons do not divide further and enter Go phase. PHASES OF MITOSIS PROPHASE: in this phase the chromatin material begins to condense in the form of chromosomes and the centrioles begin to form spindle fibers or asters. METAPHASE: in this phase nuclear envelop breaks and microtubules developed from spindle fibers bind to kinetochore of chromatids and arrange them in middle region forming a metaphase plate. ANAPHASE: in this phase kinetochore microtubules constrict seperating the conjoined chromatids and movig them to opposite poles. TELOPHASE: the two groups of identical chromosomes on opposite poles de-condense and a nuclear envelope forms around both of them and it marks end of mitosis.
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Embryology is literally “the study of the embryo”. More generally it refers to “the study of prenatal development” Defination: ‘’The study of the process of growth and differentiation of the embryo, starting from fertilization of an ovum and progressing to a fully formed individual animal.’’ Although a mammalian body is made up of an array of organ system, tissues and individual cells which function in a highly coordinated manner but they are all derived from a single cell, fertilized ovum. Ontogeny : stages of development of an individual Teratology : study of abnormal development (congenital malformations) Developmental Stages Of Embryo: Fertilization Cleavage Gastrulation Organogenesis Maturation CELL CYCLE Cells associated with formation and regeneration are somatic cells and they divide through mitosis. Cells associated with reproduction are known as germ cells including male female gametes, they divide through meiosis. Somatic cells undergo a series of molecular and morphological changes as part of the cell cycle. The changes occur in four phases G1, S, G2, and M and also a quiescent Go phase. G1 and G2 phase are known as resting phases. The cells are metabolically active fulfilling its requirements for the next phase of cycle. In S phase DNA synthesis occurs before chromosomal replication. Collectively G1,S and G2 phase form the interphase which is the preparatory phase before mitotic phase. Certain fully differentiated cells such as neurons do not divide further and enter Go phase. PHASES OF MITOSIS PROPHASE: in this phase the chromatin material begins to condense in the form of chromosomes and the centrioles begin to form spindle fibers or asters. METAPHASE: in this phase nuclear envelop breaks and microtubules developed from spindle fibers bind to kinetochore of chromatids and arrange them in middle region forming a metaphase plate. ANAPHASE: in this phase kinetochore microtubules constrict seperating the conjoined chromatids and movig them to opposite poles. TELOPHASE: the two groups of identical chromosomes on opposite poles de-condense and a nuclear envelope forms around both of them and it marks end of mitosis.
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Student notes mitosis
1.
Chromosome 1. Genetic materials 2. Tells
us who we are 3. Inside the nucleus 4. Inside in all living things
2.
Chromosome - How many
chromosomes do humans have? - Each cell has 46 chromosomes - (2 sets of 23)
3.
Cell division - Two
types of Cell division - Mitosis: produces all types of cells (Body Cells) - Example) Body cells (brain cells, muscle cells, skin cells etc) - Meiosis: Produce gametes - Example) Sperm cells and egg cells
4.
Cell Division 1) Interphase 2)
Mitosis (prophase, metaphase, anaphase, telophase) 3) Cytokinesis
5.
Interphase ● Period of
growth & DNA is duplicated
6.
Prophase
7.
Metaphase
8.
Anaphase
9.
Tel0phase
10.
After cytokinesis
11.
After mitosis ● Body
produces exactly the same daughter cells as the parent cells ● If parent cells have 40 chromosomes, after the cell division, it will produce 2 daughter cells with 40 chromosomes ● Identical cells (cloning)
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