This document discusses the history and development of safety standards for dental materials from the early 20th century to present day. It describes how the U.S. Army's request in 1919 for the National Bureau of Standards to develop amalgam specifications led to the first efforts to test dental materials. Over subsequent decades, organizations like the American Dental Association and U.S. Food and Drug Administration took on larger roles in creating standards, reviewing new materials, and regulating safety. The document also outlines the involvement of international groups like FDI and ISO in harmonizing standards globally.