Prof.Dr. Dr. Mustafa Bozbuğa hasta arşivinden bazı örnekler.

1. DEPARTMENT OF NEUROSURGERY
PROF. DR. MUSTAFA BOZBUĞA, MD, PhD

2. CENTER of NEUROSCIENCES
 Neurosurgery
 Neurology
 Neuroanesthesiology and Intensive Care Unit
 Neuroradiology
 Neuropathology
 Neurorehabilitation

3. DEPARTMENT OF NEUROSURGERY
• GENERAL MICRONEUROSURGERY
 Neuro-oncologic operations,
 Skull base surgery operations,
 Cerebrovascular cases,
 Microvascular decompression operations,
 Spinal surgery operations,
 Pediatric neurosurgical operations,
 ….

4. FACULTY of
MEDICINE
İstanbul Faculty of Medicine, University of İstanbul
1977 - 1983
NEUROSURGERY
RESIDENCY
TRAINING
Department of Neurosurgery
İstanbul Faculty of Medicine, University of İstanbul
1985 - 1991
ASSOCIATE
PROFESSOR in
NEUROSURGERY
1999
DOCTORAL
DEGREE in
ANATOMY (PhD)
Department of Anatomy
İstanbul Faculty ofMedicine, University of İstanbul
1998 - 2004
PROFESSOR in
NEUROSURGERY
2007

5. INTERNATIONAL TRAINING
“Clinical and Microneurosurgical Training”
in the Department of Neurosurgery of Zürich University Hospital
Prof. Dr. M. Gazi Yaşargil
1988
&
1989
“Fellowship in “Cranial Base Surgery and Microneurosurgery”
Department of Neurosurgery of School of Medicine,
George Washington University, Washington, DC, USA
Prof. Dr. L. N. Sekhar
May 1993 –
May 1994
“Fellowship in “Cranial Base Surgery and Microneurosurgery”
Department of Neurosurgery of School of Medicine
Osaka City University, Osaka, Japan
Prof. Dr. Akira Hakuba
June 1994 –
October 1994

6. Neuro-oncology - Case 1
• G.Ç., 38-year-old female patient,
• GCS:13
• Headache for 5 years (progressive)
• Gait disturbance
• Generalized tonic-clonic seizures for two months
• Visual impairment on the left eye
• Left V1,V2,V3 hypoesthesia
• Left hemiparesis (4/5)
• Dysphagia

12. • Combined left transsylvian, anterior temporal,
suboccipital retrosigmoid and transpetrosal-
presigmoid approach
• Total tumor removal was performed

13. POSTOPERATIVE IMAGING

15. • Post-operative 5-day lumbar drainage
• Left facial paresis, partially improved
• Right hemiparesis (4/5), resolved
• Pathology: Meningioma
• No residual tumor/recurrence in the long-term
follow-up.

16. Neuro-oncology - Case 2
• M.M.T. 14-year-old girl
• Right-sided severe headache -1 year
• VI. nerve paresis
• Diplopia
• Blurred vision
• Nausea, vomiting
• Bilateral papilloedema

21. • Right extended frontotemporosphenoidal
craniotomy
+ Right orbitozygomatic osteotomy
+ Drilling of the greater sphenoid wing,…
 Combined transsylvian and anterior
temporal approach
• Total tumor removal was achieved.

22. • Pathologic diagnosis: Chordoma

25. Neuro-oncology - Case 3
• N. K.,33-year-old female patient
• Headache,
• Right-sided hearing loss-6 months
• V1,V2 hypoesthesia
• Right facial paresis
• Right ataxic gait
• Cerebellar tests minimally impaired on the right

26. Cranial MRI: Right cerebellopontin intensely
enhancing giant extraaxial mass lesion,
suggesting a meningioma…

31. • Right suboccipital retrosigmoid approach
• Total tumor resection
• Postoperative period without any problem.

34. • Pathology: Transitional meningioma
• Follow-up 5 years,
• Late MRI: No recurrence of the tumor

35. Neuro-oncology - Case 4
• A. Ö., 76-year-old man,
• Headache, protrusion on his parietal region
• Neurologically intact.

36. Preop Cranial CT

39. SURGERY
• Right occipital craniectomy,
• Total resection of the tumor + Cranioplasty

40. Postop Cranial CT

41. Postop Cranial MRI

42. Pathology: Meningioma
Normal postoperative period
without any deficit/complication.

43. Neuro-oncology - Case 5
• 72-year-old female patient
• Headache
• Cerebellar tests impaired on the left

47. SURGERY
• Left retrosigmoid approach
• Total tumor resection

49. • Normal neurological examination,
without any deficit/complication
• Histopathology: Transitional meningioma
• Follow-up three years: No recurrence

50. Neuro-oncology - Case 6
• 35-year-old-male,
• Progressive
headache and
loss of vision for
three months.

51.  Acuityofvisionisimpressedmarkedly,
 Anosmia (+),…

52. - Bifrontal craniotomy, subfrontal approach,
- Total resection of the tumor,
- Partial improvement in vision postoperatively,
- No complication,
- Pathology: Meningoteliamatosis type meningioma.

53. Cerebro-vascular - Case 1
• HP: 53 year-old-female patient,
• Acute, severe headache
• GCS 14, Neurodeficit (-) (WFNS grade 2)
• Fisher grade 3

57. SURGERY
• Left suboccipital retrosigmoid approach
• Aneurysm clipped,
• The patient recovered well.

58. POSTOP MRA

59. POSTOP DSA

60. Cerebro-vascular - Case 2
• 56-year-old-man,
• Headache (chronic-progressive, for about one-year)
• Neurologically intact
• Cranial MRI:
• pituitary macroadenoma
• incidental AComA aneurysm

64. SURGERY
• Left pterional trans-sylvian approach
• AComA Aneurysm clipped
• Discharged without any
deficit/complication.

66. Cerebro-vascular - Case 3
• ST: 43-year-old-female patient
• Headache (acute, severe, for the last a few hours)
• GKS 13 (WFNS grade 2)
• Fisher grade III

70. SURGERY
• Right pterional trans-sylvian approach
• Proksimal ICA Aneurysm clipped

73. Cerebro-vascular - Case 4
DÖ: 59-year-old-male patient,
• Acute, severe headache
• GCS 14 (WFNS grade 2)
• Fisher grade 4

77. SURGERY
• Left pterional trans-sylvian approach
• AcomA Aneurysm clipped without any
problem,
• The patient recovered well.

79. Cerebro-vascular - Case 5
• S.Ç.: 32-year-old-female
• Acute severe headache, N&V
• Loss of consciousness,
• Focal neurological deficits: Hemiparesis, disphasia,

83. SURGERY
• Left frontoparietal large craniotomy
• Total resection of the AVM
• The patient recovered well.