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EXTRA-AXIAL BRAIN TUMORS
Dr Liaqat Mahmood Awan
FCPS
Neurosurgery
Definition
 Brain tumour located outside the brain tissue,
either in the subarachnoid space or arising from
the meninges
 External to Pia matter(meninges, nerve sheath)
EXTRA-AXIAL TUMORS
 Meningioma
 Schwannoma
 Pituitary adenoma
 Craniopharyngioma
 Dermoid/epidermoid/arachnoid cyst
 Radiologically recognized by their specific
appearance
 Often being surrounded by CSF
 Enlarging the subarachnoid space or cistern in which
they are located
 Having broadbased attachments to the dura or bone
 Compress the adjacent brain without infiltrating it
 They should be differentiated from an exophytic
growth of intra-axial tumors
 In children, extra-axial tumors are much rarer
than intra-axial, particularly in the posterior
fossa.
Symptoms & Diagnosis
 Increased intracranial pressure
 Hemispheric /lobar dysfucntion
 Endocrinologic dysfunction
 Cranial nerve dysfunction
Symptoms will vary depending on the tumor's
location, size and rate of growth
Brain tumors can mimics other neurological
disorders.
Diagnosis
 History and clinical examination
 Relevant Investigations
 MRI without & with IV contrast
 CT Scan without & with IV contrast
 PET Scan can be used
 To see the difference between scar tissue, recurring
tumor cells, and radiation necrosis
 Biopsy
 The most accurate method of diagnosis
 Can be open or close
 A 45 yr old female presented with headache for
2 years , vomiting off and on , recent onset
memory disturbance & occasional behavioral
disturbance.
 On examination patient is conscious and frontal
lobar function were impaired & have bilateral
anosmia
 Diagnosis??????
A Well-defined Contrast-enhancing Lesion In The Anterior Skull Base
 Olfactory groove meningioma
 Esthesioneuroblastoma
 Butterfly gliomas
 A change in behavior:
 The development of an "I don't care" attitude
 Memory loss & loss of concentration
 General confusion
 Infertility or amenorrhea
 A seizure with ICH that results from a fall may
actually be caused by tumors
 Patient was planned for elective tumor removal
via anterior skull base approach
 Postoperatively patient developed CSF
rhinorrhea
 How you will manage
 How you would avoid this complication
 A 69-year-old male presenting with headache
nausea , vomiting , Seizures , vision changes
diplopia and loss of sense of smell
NCCT & CECT
T1 axial c+& sag
 Craniotomy and excision
 Histopathology confirmed diagnosis as
meningioma
 48 year female presented with headaches off and
on 3 years and seizure since 4 months. she
gradually developed Rt sided hemiparesis and
had papilledema
 Diagnosis??????
 Post-op patient recovered well but after 6 hours
patients deteriorated and his GCS was 10/15
with unequal pupils
 What would be the reason for this deterioration
 How you will manage and prevent this
 Possible factors
 1. Haematoma
 2. Edema
 3.Infarct
 How you will manage
 ABC
 CT Scan plain
 Treatment of the cause
 34 year old male presented with headaches,
vomitting dysphaisa, sizures ,diplopia and right
sided weakness. He was also having papilledema
 Diagnosis????
 what would be the Surgical approach
 complications
 26 year old female presented with headache and
vomiting. she gradually developed left sided foot
drop
 Diagnosis ?????
 Parasagittal meningioma
 Parafalcine meningioma
 Patient underwent craniotomy and excision of
tumor
 Patient recovery from anesthesia was uneventful
and shifted to ward
 After three days patient gradually became
drowsy and started having vomiting
 What would be the reason for her deterioration
and how will you manage and avoid such
complications
 Possible causes
 1.venous infarct
 2. Sagittal sinus thrombosis
 3. Haematoma
 4.Electrolyte imbalance
 30 year female presented with progressive
hearing loss for the last 6 years, headaches ,
vomiting & vertigo for the last 3 months.
 she has nasal regurgitation. Now she is unable to
walk without support because of poor balance
and eye sight .
 Diagnosis?????
 1.Acoustic schawanoma
 2.Meningioma
 3.Epidermoid
 She has undergone retromastoid craniectomy
and excision of tumor after that she has not
woken up.
 1.what is gone wrong with her?
 2.how would you manage her ?
 What has gone wrong
 Brain stem injury
 Acute hydrocephalus
 Clot in the tumor bed
 Overdosage of anesthetic gases
 How would you manage
 ABC
 CT scan plain
 Manage accordingly
 How you can avoid such complications
 Pre-op planning
 Surgical technique
 Vigilant post-op monitoring
 A 41-year-old presented with dizziness and
progressive hearing loss in the right ear,
 Decreased right corneal reflex
 Right facial nerve palsy
 Diagnosis?
MRI T1&T2
T1 +C
 Schwanoma resected via right Suboccipital
approach.
 Postoperatively, she had complete right facial
paralysis.
 How you can manage and prevent this
complication
 30 year male presented with hoarsness 4
months , Regurgitation 3 months, Headache 1
½ months, Vertigo 1 ½ months, Decreased
hearing left ear
 Diagnosis ??
 Tumor excised via suboccipital craniectomy
 Postoperatively patient had difficulty in
swallowing with regurgitaion
 How you will manage this patient
 33 year female presented with headache,
vomiting and truncal ataxia with verticle
nystagmus and papilledema
 Arcahnoid cyst excised via suboccipital
craniectomy
 What are the postop complications
 What are other treatment options

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final lec brain tumors.pptxtumorrrrrrrrrrrrrrrrrrrrrrrrrrrrr

  • 1. EXTRA-AXIAL BRAIN TUMORS Dr Liaqat Mahmood Awan FCPS Neurosurgery
  • 2. Definition  Brain tumour located outside the brain tissue, either in the subarachnoid space or arising from the meninges  External to Pia matter(meninges, nerve sheath)
  • 3. EXTRA-AXIAL TUMORS  Meningioma  Schwannoma  Pituitary adenoma  Craniopharyngioma  Dermoid/epidermoid/arachnoid cyst
  • 4.  Radiologically recognized by their specific appearance  Often being surrounded by CSF  Enlarging the subarachnoid space or cistern in which they are located  Having broadbased attachments to the dura or bone  Compress the adjacent brain without infiltrating it
  • 5.  They should be differentiated from an exophytic growth of intra-axial tumors  In children, extra-axial tumors are much rarer than intra-axial, particularly in the posterior fossa.
  • 6. Symptoms & Diagnosis  Increased intracranial pressure  Hemispheric /lobar dysfucntion  Endocrinologic dysfunction  Cranial nerve dysfunction Symptoms will vary depending on the tumor's location, size and rate of growth Brain tumors can mimics other neurological disorders.
  • 7. Diagnosis  History and clinical examination  Relevant Investigations
  • 8.  MRI without & with IV contrast  CT Scan without & with IV contrast  PET Scan can be used  To see the difference between scar tissue, recurring tumor cells, and radiation necrosis  Biopsy  The most accurate method of diagnosis  Can be open or close
  • 9.  A 45 yr old female presented with headache for 2 years , vomiting off and on , recent onset memory disturbance & occasional behavioral disturbance.  On examination patient is conscious and frontal lobar function were impaired & have bilateral anosmia  Diagnosis??????
  • 10. A Well-defined Contrast-enhancing Lesion In The Anterior Skull Base
  • 11.  Olfactory groove meningioma  Esthesioneuroblastoma  Butterfly gliomas
  • 12.  A change in behavior:  The development of an "I don't care" attitude  Memory loss & loss of concentration  General confusion  Infertility or amenorrhea  A seizure with ICH that results from a fall may actually be caused by tumors
  • 13.  Patient was planned for elective tumor removal via anterior skull base approach  Postoperatively patient developed CSF rhinorrhea  How you will manage  How you would avoid this complication
  • 14.  A 69-year-old male presenting with headache nausea , vomiting , Seizures , vision changes diplopia and loss of sense of smell
  • 17.  Craniotomy and excision  Histopathology confirmed diagnosis as meningioma
  • 18.  48 year female presented with headaches off and on 3 years and seizure since 4 months. she gradually developed Rt sided hemiparesis and had papilledema  Diagnosis??????
  • 19.
  • 20.
  • 21.  Post-op patient recovered well but after 6 hours patients deteriorated and his GCS was 10/15 with unequal pupils  What would be the reason for this deterioration  How you will manage and prevent this
  • 22.  Possible factors  1. Haematoma  2. Edema  3.Infarct  How you will manage  ABC  CT Scan plain  Treatment of the cause
  • 23.  34 year old male presented with headaches, vomitting dysphaisa, sizures ,diplopia and right sided weakness. He was also having papilledema  Diagnosis????
  • 24.
  • 25.
  • 26.
  • 27.  what would be the Surgical approach  complications
  • 28.  26 year old female presented with headache and vomiting. she gradually developed left sided foot drop  Diagnosis ?????
  • 29.
  • 30.
  • 31.
  • 32.  Parasagittal meningioma  Parafalcine meningioma
  • 33.  Patient underwent craniotomy and excision of tumor  Patient recovery from anesthesia was uneventful and shifted to ward  After three days patient gradually became drowsy and started having vomiting
  • 34.  What would be the reason for her deterioration and how will you manage and avoid such complications
  • 35.  Possible causes  1.venous infarct  2. Sagittal sinus thrombosis  3. Haematoma  4.Electrolyte imbalance
  • 36.  30 year female presented with progressive hearing loss for the last 6 years, headaches , vomiting & vertigo for the last 3 months.  she has nasal regurgitation. Now she is unable to walk without support because of poor balance and eye sight .  Diagnosis?????
  • 37.  1.Acoustic schawanoma  2.Meningioma  3.Epidermoid
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.  She has undergone retromastoid craniectomy and excision of tumor after that she has not woken up.  1.what is gone wrong with her?  2.how would you manage her ?
  • 44.  What has gone wrong  Brain stem injury  Acute hydrocephalus  Clot in the tumor bed  Overdosage of anesthetic gases
  • 45.  How would you manage  ABC  CT scan plain  Manage accordingly  How you can avoid such complications  Pre-op planning  Surgical technique  Vigilant post-op monitoring
  • 46.  A 41-year-old presented with dizziness and progressive hearing loss in the right ear,  Decreased right corneal reflex  Right facial nerve palsy  Diagnosis?
  • 48. T1 +C
  • 49.  Schwanoma resected via right Suboccipital approach.  Postoperatively, she had complete right facial paralysis.  How you can manage and prevent this complication
  • 50.  30 year male presented with hoarsness 4 months , Regurgitation 3 months, Headache 1 ½ months, Vertigo 1 ½ months, Decreased hearing left ear  Diagnosis ??
  • 51.
  • 52.
  • 53.
  • 54.  Tumor excised via suboccipital craniectomy  Postoperatively patient had difficulty in swallowing with regurgitaion  How you will manage this patient
  • 55.  33 year female presented with headache, vomiting and truncal ataxia with verticle nystagmus and papilledema
  • 56.
  • 57.
  • 58.
  • 59.  Arcahnoid cyst excised via suboccipital craniectomy  What are the postop complications  What are other treatment options