Subarachnoid Hemorrhage
(SAH)
Ionuţ Cărăvan
Coordinated by Prof. Ioan Ştefan Florian, MD, PhD
University of Medicine and Pharmacy
ā€œIuliu HaÅ£ieganuā€œ Cluj Napoca
Definition
• SAH = extravasation of blood into the subarachnoid
space
Etiology
Greenberg Handbook of Neurosurgery, 2010
ļ‚§ Traumatic SAH
ļ‚§ Non-traumatic (spontaneous) SAH
oruptured intracranial aneurysms (75 %)
oAVM (5 %)
oothers (tumor, vasculitis, coagulation disorders, dural
sinus thrombosis)
ounknown etiology (15 %)=ā€œangiogram-negative SAHā€
Presenting features(1)
• HEADACHE (ā€œthunderclap headacheā€)
• meningismus
ļ‚§ neck stiffness
ļ‚§ photophobia
ļ‚§ back pain
Presenting features(2)
• decreased state of consciousness
• nausea and vomiting
• seizures
• focal neurologic deficits:
ļ‚§ oculomotor palsy
ļ‚§ hemiparesis
• ocular hemorrhage
Radiographic findings
• CT scan
• Cerebral Angiography
• FLAIR* MRI
• CT Angiography
• MRA**
*Fluid-attenuated inversion recovery
**Magnetic Resonance Angiography
CT scan
Lumbar puncture
Grading SAH
Hunt and Hess Grade WFNS* Grading
*World Federation of Neurological Surgeons
Complications
• Hydrocephalus
• Vasospasm => delayed cerebral ischemia
• Seizures
• Rebleeding
• Intracerebral hemorrhage
• Intraventricular hemorrhage
• Left ventricular systolic dysfunction
• Subdural hematoma
Treatment
• BP control (fluid restriction and antihypertensive therapy) when the
mean arterial pressure exceeds 130 mm Hg
• ICP control (osmotic agents, loop diuretics)
• Symptomatic treatment:
– anticonvulsants: levetiracetam, phenytoin
– analgesics: fentanyl
– anti-emetics: odansetron
– calcium channel blockers: nimodipine, verapamil => vasospasm
!!! Prevention of rebleeding:
• antifibrinolytic therapy
• surgical treatment
• endovascular treatment
References
• MS Greenberg. Handbook of Neurosurgery. Seventh Edition.
New York: Thieme Medical Publishers; 2010.
• AH Kaye. Essential Neurosurgery. Third Edition. Oxford:
Blackwell Publishing Ltd; 2005.
• MG Yasargil. Microneurosurgery. New York: Thieme Medical
Publishers Inc; 1994.
Thank you!

Subarachnoid Hemorrhage

  • 1.
    Subarachnoid Hemorrhage (SAH) IonuÅ£ Cărăvan Coordinatedby Prof. Ioan Ştefan Florian, MD, PhD University of Medicine and Pharmacy ā€œIuliu HaÅ£ieganuā€œ Cluj Napoca
  • 2.
    Definition • SAH =extravasation of blood into the subarachnoid space
  • 3.
    Etiology Greenberg Handbook ofNeurosurgery, 2010 ļ‚§ Traumatic SAH ļ‚§ Non-traumatic (spontaneous) SAH oruptured intracranial aneurysms (75 %) oAVM (5 %) oothers (tumor, vasculitis, coagulation disorders, dural sinus thrombosis) ounknown etiology (15 %)=ā€œangiogram-negative SAHā€
  • 4.
    Presenting features(1) • HEADACHE(ā€œthunderclap headacheā€) • meningismus ļ‚§ neck stiffness ļ‚§ photophobia ļ‚§ back pain
  • 5.
    Presenting features(2) • decreasedstate of consciousness • nausea and vomiting • seizures • focal neurologic deficits: ļ‚§ oculomotor palsy ļ‚§ hemiparesis • ocular hemorrhage
  • 6.
    Radiographic findings • CTscan • Cerebral Angiography • FLAIR* MRI • CT Angiography • MRA** *Fluid-attenuated inversion recovery **Magnetic Resonance Angiography
  • 7.
  • 8.
  • 9.
    Grading SAH Hunt andHess Grade WFNS* Grading *World Federation of Neurological Surgeons
  • 10.
    Complications • Hydrocephalus • Vasospasm=> delayed cerebral ischemia • Seizures • Rebleeding • Intracerebral hemorrhage • Intraventricular hemorrhage • Left ventricular systolic dysfunction • Subdural hematoma
  • 11.
    Treatment • BP control(fluid restriction and antihypertensive therapy) when the mean arterial pressure exceeds 130 mm Hg • ICP control (osmotic agents, loop diuretics) • Symptomatic treatment: – anticonvulsants: levetiracetam, phenytoin – analgesics: fentanyl – anti-emetics: odansetron – calcium channel blockers: nimodipine, verapamil => vasospasm !!! Prevention of rebleeding: • antifibrinolytic therapy • surgical treatment • endovascular treatment
  • 12.
    References • MS Greenberg.Handbook of Neurosurgery. Seventh Edition. New York: Thieme Medical Publishers; 2010. • AH Kaye. Essential Neurosurgery. Third Edition. Oxford: Blackwell Publishing Ltd; 2005. • MG Yasargil. Microneurosurgery. New York: Thieme Medical Publishers Inc; 1994.
  • 13.