R b t uo g srey
 o oi rl y ug r
     c o
a p o l l o m e d i c i n e 1 0 ( 2 0 1 3 ) 9 8 e9 9



                                           Available online at www.sciencedirect.com




                                   journal homepage: www.elsevier.com/locate/apme



Journal Scan

Robotic urology surgery

Arun Prasad*
Apollo Hospital, Department of Surgery, Room 1202, 2nd Floor B Wing, Sarita Vihar, New Delhi 110044, India




  Positive surgical margin and perioperative complication rates of primary surgical treatments for prostate cancer: a sys-
  tematic review and meta-analysis comparing retropubic, laparoscopic, and robotic prostatectomy. Ashutosh Tewari,
  Prasanna Sooriakumaran, Daniel A. Bloch, Usha Seshadri-Kreaden, April E. Hebert, Peter Wiklund. Eur Urol. July
  2012;62(1):e1ee30.


  Abstract


  Context: Radical prostatectomy (RP) approaches have rarely been compared adequately with regard to margin and peri-
  operative complication rates.
  Objective: Review the literature from 2002 to 2010 and compare margin and perioperative complication rates for open
  retropubic RP (ORP), laparoscopic RP (LRP), and robot-assisted LRP (RALP).
  Evidence acquisition: Summary data were abstracted from 400 original research articles representing 167,184 ORP, 57,303
  LRP, and 62,389 RALP patients (total: 286,876). Articles were found through PubMed and Scopus searches and met a priori
  inclusion criteria (eg, surgery after 1990, reporting margin rates and/or perioperative complications, study size > 25 cases).
  The primary outcomes were positive surgical margin (PSM) rates, as well as total intra- and perioperative complication rates.
  Secondary outcomes included blood loss, transfusions, conversions, length of hospital stay, and rates for specific individual
  complications. Weighted averages were compared for each outcome using propensity adjustment.
  Evidence synthesis: After propensity adjustment, the LRP group had higher positive surgical margin rates than the RALP
  group but similar rates to the ORP group. LRP and RALP showed significantly lower blood loss and transfusions, and a shorter
  length of hospital stay than the ORP group. Total perioperative complication rates were higher for ORP and LRP than for
  RALP. Total intraoperative complication rates were low for all modalities but lowest for RALP. Rates for readmission,
  reoperation, nerve, ureteral, and rectal injury, deep vein thrombosis, pneumonia, hematoma, lymphocele, anastomotic leak,
  fistula, and wound infection showed significant differences between groups, generally favoring RALP. The lack of ran-
  domized controlled trials, use of margin status as an indicator of oncologic control, and inability to perform cost compar-
  isons are limitations of this study.
  Conclusions: This meta-analysis demonstrates that RALP is at least equivalent to ORP or LRP in terms of margin rates and
  suggests that RALP provides certain advantages, especially regarding decreased adverse events.

Take home message
Radical prostatectomy is generally a safe operation with few complications and low positive surgical margin rates. However,
robotic assistance appears to provide superior outcomes in this regard compared with open retropubic and conventional lapa-
roscopic approaches for most surgeons.




 * Tel.: þ91 11 29871202.
   E-mail address: surgerytimes@gmail.com.
0976-0016/$ e see front matter
http://dx.doi.org/10.1016/j.apme.2013.01.001
a p o l l o m e d i c i n e 1 0 ( 2 0 1 3 ) 9 8 e9 9                            99



  A comparison of laparoscopic pyeloplasty performed with the daVinci robotic system versus standard laparoscopic tech-
  niques: initial clinical results. Matthew T Gettman, Reinhard Peschel, Richard Neururer, Georg Bartsch. Eur Urol. November
  2002;42(5):417e532.


  Abstract


  Purpose: Laparoscopic pyeloplasty is an accepted therapy for primary ureteropelvic junction obstruction (UPJO), however
  difficulty associated with intracorporeal suturing has limited widespread clinical application. We report our initial expe-
  rience of laparoscopic pyeloplasty performed with the daVinci robotic system matched to procedures performed with
  standard laparoscopic techniques.
  Patients and Methods: From June 2001 until August 2001, six patients underwent definitive management of primary UPJO
  using the daVinci robotic system. In four patients an AndersoneHynes pyeloplasty was performed, while in two patients
  Fengerplasty was performed. Using demographic and preoperative information, each patient in the daVinci-assisted group
  was matched to a corresponding patient with primary UPJO undergoing laparoscopic pyeloplasty with standard techniques
  between November 1999 and June 2001. Perioperative results and follow-up data were subsequently compared.
  Results: Treatment groups were identical with regard to surgical procedure, gender, and side of UPJO. The length of hos-
  pitalization was 4 days for all patients, regardless of treatment group. Estimated blood loss was <50 cc in all cases. For
  AndersoneHynes pyeloplasty, the mean overall operative and suturing times were 140 and 70 min using the daVinci system
  and 235 and 120 min using standard techniques, respectively. For the Fengerplasty, the mean overall operative and suturing
  times were 78 and 13 min using the daVinci system and 100 and 28 min using standard techniques, respectively. No
  complications were observed and there were no open conversions.
  Conclusion: AndersoneHynes pyeloplasty and Fengerplasty are feasible using either conventional laparoscopic techniques
  or the daVinci robotic system. In this initial pilot study, procedures performed with the daVinci robotic system resulted in
  overall decreased operative time, however factors responsible for the decreased operative time remain to be defined. Long-
  term prospective follow-up of procedures performed with or without the daVinci robotic system for surgeons with limited
  experience in laparoscopic management of UPJO is warranted to delineate the true efficacy of the device.


Albert Einstein is credited with saying, ‘‘Not everything that can be counted counts, and not everything that counts can be
counted.’’ Many nuances of robotic surgery cannot be counted, but Tewari and colleagues have done an extraordinary job of
counting what can be counted.
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Robotic urology surgery

  • 1.
    R b tuo g srey o oi rl y ug r c o
  • 2.
    a p ol l o m e d i c i n e 1 0 ( 2 0 1 3 ) 9 8 e9 9 Available online at www.sciencedirect.com journal homepage: www.elsevier.com/locate/apme Journal Scan Robotic urology surgery Arun Prasad* Apollo Hospital, Department of Surgery, Room 1202, 2nd Floor B Wing, Sarita Vihar, New Delhi 110044, India Positive surgical margin and perioperative complication rates of primary surgical treatments for prostate cancer: a sys- tematic review and meta-analysis comparing retropubic, laparoscopic, and robotic prostatectomy. Ashutosh Tewari, Prasanna Sooriakumaran, Daniel A. Bloch, Usha Seshadri-Kreaden, April E. Hebert, Peter Wiklund. Eur Urol. July 2012;62(1):e1ee30. Abstract Context: Radical prostatectomy (RP) approaches have rarely been compared adequately with regard to margin and peri- operative complication rates. Objective: Review the literature from 2002 to 2010 and compare margin and perioperative complication rates for open retropubic RP (ORP), laparoscopic RP (LRP), and robot-assisted LRP (RALP). Evidence acquisition: Summary data were abstracted from 400 original research articles representing 167,184 ORP, 57,303 LRP, and 62,389 RALP patients (total: 286,876). Articles were found through PubMed and Scopus searches and met a priori inclusion criteria (eg, surgery after 1990, reporting margin rates and/or perioperative complications, study size > 25 cases). The primary outcomes were positive surgical margin (PSM) rates, as well as total intra- and perioperative complication rates. Secondary outcomes included blood loss, transfusions, conversions, length of hospital stay, and rates for specific individual complications. Weighted averages were compared for each outcome using propensity adjustment. Evidence synthesis: After propensity adjustment, the LRP group had higher positive surgical margin rates than the RALP group but similar rates to the ORP group. LRP and RALP showed significantly lower blood loss and transfusions, and a shorter length of hospital stay than the ORP group. Total perioperative complication rates were higher for ORP and LRP than for RALP. Total intraoperative complication rates were low for all modalities but lowest for RALP. Rates for readmission, reoperation, nerve, ureteral, and rectal injury, deep vein thrombosis, pneumonia, hematoma, lymphocele, anastomotic leak, fistula, and wound infection showed significant differences between groups, generally favoring RALP. The lack of ran- domized controlled trials, use of margin status as an indicator of oncologic control, and inability to perform cost compar- isons are limitations of this study. Conclusions: This meta-analysis demonstrates that RALP is at least equivalent to ORP or LRP in terms of margin rates and suggests that RALP provides certain advantages, especially regarding decreased adverse events. Take home message Radical prostatectomy is generally a safe operation with few complications and low positive surgical margin rates. However, robotic assistance appears to provide superior outcomes in this regard compared with open retropubic and conventional lapa- roscopic approaches for most surgeons. * Tel.: þ91 11 29871202. E-mail address: surgerytimes@gmail.com. 0976-0016/$ e see front matter http://dx.doi.org/10.1016/j.apme.2013.01.001
  • 3.
    a p ol l o m e d i c i n e 1 0 ( 2 0 1 3 ) 9 8 e9 9 99 A comparison of laparoscopic pyeloplasty performed with the daVinci robotic system versus standard laparoscopic tech- niques: initial clinical results. Matthew T Gettman, Reinhard Peschel, Richard Neururer, Georg Bartsch. Eur Urol. November 2002;42(5):417e532. Abstract Purpose: Laparoscopic pyeloplasty is an accepted therapy for primary ureteropelvic junction obstruction (UPJO), however difficulty associated with intracorporeal suturing has limited widespread clinical application. We report our initial expe- rience of laparoscopic pyeloplasty performed with the daVinci robotic system matched to procedures performed with standard laparoscopic techniques. Patients and Methods: From June 2001 until August 2001, six patients underwent definitive management of primary UPJO using the daVinci robotic system. In four patients an AndersoneHynes pyeloplasty was performed, while in two patients Fengerplasty was performed. Using demographic and preoperative information, each patient in the daVinci-assisted group was matched to a corresponding patient with primary UPJO undergoing laparoscopic pyeloplasty with standard techniques between November 1999 and June 2001. Perioperative results and follow-up data were subsequently compared. Results: Treatment groups were identical with regard to surgical procedure, gender, and side of UPJO. The length of hos- pitalization was 4 days for all patients, regardless of treatment group. Estimated blood loss was <50 cc in all cases. For AndersoneHynes pyeloplasty, the mean overall operative and suturing times were 140 and 70 min using the daVinci system and 235 and 120 min using standard techniques, respectively. For the Fengerplasty, the mean overall operative and suturing times were 78 and 13 min using the daVinci system and 100 and 28 min using standard techniques, respectively. No complications were observed and there were no open conversions. Conclusion: AndersoneHynes pyeloplasty and Fengerplasty are feasible using either conventional laparoscopic techniques or the daVinci robotic system. In this initial pilot study, procedures performed with the daVinci robotic system resulted in overall decreased operative time, however factors responsible for the decreased operative time remain to be defined. Long- term prospective follow-up of procedures performed with or without the daVinci robotic system for surgeons with limited experience in laparoscopic management of UPJO is warranted to delineate the true efficacy of the device. Albert Einstein is credited with saying, ‘‘Not everything that can be counted counts, and not everything that counts can be counted.’’ Many nuances of robotic surgery cannot be counted, but Tewari and colleagues have done an extraordinary job of counting what can be counted.
  • 4.
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