The document discusses making the pharmaceutical supply chain more effective and engaging the commercial function. It notes that currently: 1) Lead times in the pharma supply chain are long, up to 400 days, and inventory turnover is low. 2) Stock outs are unacceptable as they affect patients' lives, but historically companies have avoided them by keeping lots of inventory. 3) To engage commercial functions like marketing, operations must provide customer insights, ensure product availability, manage risk, and challenge the status quo with innovative ideas that help drive sales and brand value. Both operations and commercial functions are essential to building effective, efficient future supply chains.