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Structure Boundary Preserving Segmentation
for Medical Image with Ambiguous Boundary
Dong Min Choi
Yonsei University Severance Hospital CCIDS
Introduction
• Two critical problems of medical image segmentation

- i) ambiguity of structure boundary

- ii) uncertainty of the segmented region without specialized
medical knowledge

• Propose a novel image segmentation method to tackle these
problems

- a novel structure boundary preserving segmentation framework
Introduction
Proposed Architecture
Overall Architecture
Proposed Architecture
1. BPB (Boundary Preserving Block)
Overall Architecture
Proposed Architecture
1. BPB (Boundary Preserving Block)
2. SBE (Shape

Boundary-aware Evaluator)
Overall Architecture
Proposed Architecture
1. BPB (Boundary Preserving Block)
2. SBE (Shape

Boundary-aware Evaluator)
Overall Architecture
Proposed Architecture
Boundary Key-point Selection Module
- Generates the boundary key points that

1) best fit the GT segmentation map 

2) represent structure boundary of the 

target region

- Steps

1) Using canny edge detection algo, 

obtain the boundary from GT

2) Select n points randomly on the 

boundary 

3) Construct the boundary region by 

connecting the n points

4) Select the boundary points with the 

highest value of IOU after T-th iterationImplement details : n=6, T=40,000
Proposed Architecture
Boundary Key-point Selection Module
- Generates the boundary key points that

1) best fit the GT segmentation map 

2) represent structure boundary of the 

target region

- Steps

1) Using canny edge detection algo, 

obtain the boundary from GT

2) Select n points randomly on the 

boundary 

3) Construct the boundary region by 

connecting the n points

4) Select the boundary points with the 

highest value of IOU after T-th iterationImplement details : n=6, T=40,000
Proposed Architecture
BPB (Boundary Preserving Block)
- Enhance boundary information in
feature-map level

- Boundary Point Map Generator

* Input : feature map 

* Output : Boundary Key-point map 

* Various receptive fields with 

( : dilation ratio and filter)

* Loss function : 

- Boundary Enhanced Feature :

fi
Mi
ds
r
ds
r r s × s
LMap
Proposed Architecture
SBE (Shape Boundary-aware Evaluator)
- A novel structure boundary information-based discrimination network

* Input : Boundary keypoint map and segmentation image ( and )

* Concat and the given segmentation image across the channel-wise

* Output : whether the segmentation results are consistent with the or not

- Used in training stage only
MGT SGT
̂SPred
MGT
MGT
Loss Function
< The Segmentation Training Loss >
*
*
*
< The Adversarial SBE Loss >
Result
Result
Result
Qualitative Results : PH2 + ISBI 2016 Challenge dataset
Result
Qualitative Results : TVUS Challenge dataset
Result
- Using 6 key points shows the best performance

- But, this number of key points is not optimal for all objects

- The more complex structures are, the more key points and iterations are needed
Conclusion
• A novel fully automatic segmentation framework for medical
image segmentation with an ambiguity boundary

• Using BPB and SBE, segmentation network further exploits the
structure boundary

• The proposed framework can easily be integrated into various
segmentation networks
Thank you

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Review : Structure Boundary Preserving Segmentation
for Medical Image with Ambiguous Boundary

  • 1. Structure Boundary Preserving Segmentation for Medical Image with Ambiguous Boundary Dong Min Choi Yonsei University Severance Hospital CCIDS
  • 2. Introduction • Two critical problems of medical image segmentation
 - i) ambiguity of structure boundary
 - ii) uncertainty of the segmented region without specialized medical knowledge • Propose a novel image segmentation method to tackle these problems
 - a novel structure boundary preserving segmentation framework
  • 5. Proposed Architecture 1. BPB (Boundary Preserving Block) Overall Architecture
  • 6. Proposed Architecture 1. BPB (Boundary Preserving Block) 2. SBE (Shape
 Boundary-aware Evaluator) Overall Architecture
  • 7. Proposed Architecture 1. BPB (Boundary Preserving Block) 2. SBE (Shape
 Boundary-aware Evaluator) Overall Architecture
  • 8. Proposed Architecture Boundary Key-point Selection Module - Generates the boundary key points that
 1) best fit the GT segmentation map 
 2) represent structure boundary of the 
 target region - Steps
 1) Using canny edge detection algo, 
 obtain the boundary from GT
 2) Select n points randomly on the 
 boundary 
 3) Construct the boundary region by 
 connecting the n points
 4) Select the boundary points with the 
 highest value of IOU after T-th iterationImplement details : n=6, T=40,000
  • 9. Proposed Architecture Boundary Key-point Selection Module - Generates the boundary key points that
 1) best fit the GT segmentation map 
 2) represent structure boundary of the 
 target region - Steps
 1) Using canny edge detection algo, 
 obtain the boundary from GT
 2) Select n points randomly on the 
 boundary 
 3) Construct the boundary region by 
 connecting the n points
 4) Select the boundary points with the 
 highest value of IOU after T-th iterationImplement details : n=6, T=40,000
  • 10. Proposed Architecture BPB (Boundary Preserving Block) - Enhance boundary information in feature-map level
 - Boundary Point Map Generator
 * Input : feature map 
 * Output : Boundary Key-point map 
 * Various receptive fields with 
 ( : dilation ratio and filter)
 * Loss function : 
 - Boundary Enhanced Feature : fi Mi ds r ds r r s × s LMap
  • 11. Proposed Architecture SBE (Shape Boundary-aware Evaluator) - A novel structure boundary information-based discrimination network
 * Input : Boundary keypoint map and segmentation image ( and )
 * Concat and the given segmentation image across the channel-wise
 * Output : whether the segmentation results are consistent with the or not - Used in training stage only MGT SGT ̂SPred MGT MGT
  • 12. Loss Function < The Segmentation Training Loss > * * * < The Adversarial SBE Loss >
  • 15. Result Qualitative Results : PH2 + ISBI 2016 Challenge dataset
  • 16. Result Qualitative Results : TVUS Challenge dataset
  • 17. Result - Using 6 key points shows the best performance - But, this number of key points is not optimal for all objects - The more complex structures are, the more key points and iterations are needed
  • 18. Conclusion • A novel fully automatic segmentation framework for medical image segmentation with an ambiguity boundary • Using BPB and SBE, segmentation network further exploits the structure boundary • The proposed framework can easily be integrated into various segmentation networks