The document summarizes the anatomy and function of the male and female reproductive systems. It describes the internal organs such as the testes, ovaries, and accessory glands. It explains sperm and egg production, hormone regulation of the menstrual cycle, and development of sperm and eggs from puberty through adulthood. Key details are provided on structures like the epididymis, ductus deferens, and follicles and their roles in sperm and egg maturation and release.
Reproductive system of man
this presentation contains the content of reproductive system of male and female with picture description and sexually transmitted diseases.
prepared by - S.lavesan and s.subangan, the students of Jaffna National college of education.
This PPT covers Anatomy and Physiology of Male Reproductive System. It includes anatomy of male reproductive organs, spermatogenesis and hormonal regulation of testis
The reproductive system is the human organ system responsible for the production and fertilization of gametes (sperm or eggs) and, in females, the carrying of a fetus. Both male and female reproductive systems have organs called gonads that produce gametes.
Reproductive system of man
this presentation contains the content of reproductive system of male and female with picture description and sexually transmitted diseases.
prepared by - S.lavesan and s.subangan, the students of Jaffna National college of education.
This PPT covers Anatomy and Physiology of Male Reproductive System. It includes anatomy of male reproductive organs, spermatogenesis and hormonal regulation of testis
The reproductive system is the human organ system responsible for the production and fertilization of gametes (sperm or eggs) and, in females, the carrying of a fetus. Both male and female reproductive systems have organs called gonads that produce gametes.
he reproductive system is a collection of internal and external organs — in both males and females — that work together for the purpose of procreating, according to the Cleveland Clinic. Due to its vital role in the survival of the species, many scientists argue that the reproductive system is among the most important systems in the entire body.
he reproductive system is a collection of internal and external organs — in both males and females — that work together for the purpose of procreating, according to the Cleveland Clinic. Due to its vital role in the survival of the species, many scientists argue that the reproductive system is among the most important systems in the entire body.
Located outside the abdominal cavity within a pouch called scrotum.
Scrotum provides low temperature required for spermatogenesis.
Each testis is about 4 to 5 cm length and 2 to 3 cm width.
Each testis has about 250 compartments called testicular lobules.
Each lobule contains one to three seminiferous tubules.
Seminiferous tubules lined by male germ cells and Sertoli cells.
Male germ cell undergoes meiosis and produce sperm.
Sertoli cells provide nutrition to the germ cell and the sperm.
In between the seminiferous tubule there is interstitial cell or Leydig
cell.
Leydig cells produce testicular hormones
called androgen (testosteron It is the primary female sex organs that produce the female
gamete (ovum).
It also produces several steroid hormones.
The ovaries located in the lower abdomen.
Each ovary is about 2-4 cm in length.
Connected to the pelvic wall and uterus by ligaments.
Each ovary is covered by thin epithelium which encloses the
ovarian stroma
The ovarian stroma has two zones
A peripheral cortex.
An inner medulla.
this chapter is completely based on complete process of reproduction from insemination to lactation,the diagrams and differences and explanations according to NCERT Syllabus.
SEXUAL LITERACY RATES IN OUR SOCIETY ARE PATHETIC AS CHILDREN RECEIVE NO SEX EDUCATION OR THEY OBTAIN ALL THEIR SEX EDUCATION AS A MATTER OF FUN FROM ALL WRONG SOURCES.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
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Hot Selling Organic intermediates
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
3. 28-3
Comparison of the Female and
Male Reproductive Systems
Female typically produces and releases
a single oocyte monthly.
Male produces 100,000,000’s of
(sperm) daily.
male gametes are stored for a short
time
if they are not expelled from the body
within that period, they are resorbed
4. 28-4
Anatomy of the Male
Reproductive System
Internal organs: testes, spermatic
cord, ductus deferens, seminal
glands, prostate.
External organs include:
The penis
The scrotum
The male urethra
5. 28-5
Testes
Small, oval organ
Housed in the scrotum
Produces:
Sperm
Androgens (testosterone).
Coverings
Serous membrane called tunica vaginalis
Parietal layer
Visceral layer.
Tunica albuginea
Forms internal septa
250 lobules per testis
Each lobule has up to 4 seminiferous
tubules
Two types of cell
Sustentacular cells
Germ cells
Interior is called mediastinum testis.
7. 28-7
Testes
Sperm develop in the semineferous tubules
Interstitial spaces: surround the seminiferous tubules.
Contain interstitial (Leydig) cells
produce hormones called androgens.
Several types of androgens
most common one is testosterone.
the adrenal cortex secretes a small amount of androgens
the vast majority of androgen release is via interstitial
cells in the testis
These hormones cause males to develop the classic
characteristics:
axillary and pubic hair
deeper voice
sperm production.
10. 28-10
The testicular tunicsThe testicular tunics
1- testis; (orchis)
2- epididymis
3- ductus deferens
4- tunica vaginalis testis
5- cavum vaginalis testis
6- fascia spermatica
interna
7- m. cremaster
8- fascia cremasterica
9- fascia spermatica
externa
10-tunica dartos
11-cutis
11. 28-11
Spermatic Cord
The blood vessels
and nerves to the
testis travel from
within the abdomen
to the scrotum in a
multilayered
structure called the
spermatic cord.
12. 28-12
Developmemt of sperm
Called spermatogenesis
Occurs in the seminiferous tubules
Process:
Spermatogonium
Primary spermatocyte
Secondary spermatocyte
Spermatid
Spermiogenesis
Spermatid matures into spermatozoon
15. 28-15
Epididymis
The epididymis is a comma-shaped structure composed of
an internal duct and an external covering of connective
tissue.
Its head lies on the superior surface of the testis, while the
body and tail are posterior to the testis.
Internally, the epididymis contains a long, convoluted duct
of the epididymis, which is approximately 4 to 5 meters in
length.
Sperm must reside in the epididymis for a period of time to
become mature and fully motile.
If they are expelled too soon, they lack the motility
necessary to travel through the female reproductive tract
and fertilize an oocyte.
If sperm are not ejected from the male reproductive system
in a timely manner, the old sperm degenerate in the
epididymis.
16. 28-16
Ductus Deferens
When sperm leave the epididymis,
they enter the ductus deferens,
also called the vas deferens.
The ductus deferens is a thick-
walled tube that travels within the
spermatic cord, through the
inguinal canal, and within the
pelvic cavity before it reaches the
prostate gland.
The ampulla of the ductus
deferens unites with the proximal
region of the seminal vesicle to
form the terminal portion of the
reproductive duct system, called
the ejaculatory duct.
18. 28-18
Urethra
Transports semen from the
ejaculatory duct to the outside of
the body.
Subdivided into:
prostatic urethra that extends
through the prostate gland
membranous urethra that
travels through the urogenital
diaphragm
penile urethra that ends
through the penis
Sperm leave the body through
the urethra.
19. 28-19
Accessory Glands
The vagina has a highly acidic environment to prevent bacterial
growth.
Sperm cannot survive in this type of environment, so an alkaline
secretion called seminal fluid is needed to lessen the acidity of the
vagina and bring pH values closer to neutral.
As the sperm travel through the reproductive tract (a process that can
take several days), they are nourished by nutrients within the seminal
fluid.
The components of seminal fluid are produced by accessory glands:
seminal vesicles
prostate gland
bulbourethral glands
21. 28-21
Seminal Vesicles
The paired seminal vesicles are located on the posterior surface
of the urinary bladder adjacent to the ampulla of the ductus
deferens.
Each seminal vesicle is an elongated, pouchlike hollow organ
approximately 5–8 centimeters long.
It is the proximal portion of each seminal vesicle that merges
with a ductus deferens to form the ejaculatory duct.
The seminal vesicles secrete a viscous, whitish-yellow alkaline
fluid containing both fructose and prostaglandins.
The fructose is a sugar that nourishes the sperm as they travel
through the female reproductive tract, while the prostaglandins
promote the widening and slight dilation of the external os of the
cervix.
22. 28-22
Prostate Gland
A compact encapsulated organ that weighs about 20 grams and
is shaped like a walnut, measuring approximately 2 cm by 3 cm
by 4 cm.
Located immediately inferior to the bladder.
Secretes a slightly milky fluid that is weakly acidic and rich in
citric acid, seminalplasmin, and prostate-specific antigen (PSA).
citric acid is a nutrient for sperm health
seminalplasmin is an antibiotic that combats urinary tract
infections
PSA acts as an enzyme to help liquefy semen following
ejaculation
23. 28-23
Bulbourethral Glands
Paired, pea-shaped
Also called Cowper’s glands
Location:
within the urogenital diaphragm
on each side of the membranous urethra.
Each gland has a short duct
projects into the base of the penis
enters the spongy urethra.
secretory product
clear, viscous mucin (forms mucus when mixed with water).
mucin protects the urethra
serves as a lubricant during sexual intercourse.
24. 28-24
Scrotum
a skin-covered sac that houses:
male gonads
first portion of the duct system
Testes exposed to elevated temperatures
Skin of the scrotal sac becomes thin
The cremaster muscle relaxes
The testes temperature becomes less than normal
body temperature.
The opposite occurs if the testes are exposed
to cold.
27. 28-27
Semen
Combination of seminal fluid from the
accessory glands and sperm.
Called the ejaculate (when released during
ejaculation)
normally about 3 to 5 milliliters
contains approximately 200 to 500 million
spermatozoa.
Average transit time: about 2 weeks
from release of sperm into the lumen of the
seminiferous tubules, passage through the duct
system, and appearance in the ejaculate.
28. 28-28
Anatomy of the Female
Reproductive System
INTERNAL organs of the female are:
the ovaries, uterine tubes, vagina
EXTERNAL organs comprise the
strructures associated with the
pudendal cleft
32. 28-32
Ovary (ovarium, oophoron)
The principal gland of female genial system,
which produces the oocytes and hormones
(estrogen and progesterone)
It is a paired flattend ovoid organ sized 1x2x3
cm
The principal substance of ovary is divided
into the ovarian cortex and ovarian medulla
33. 28-33
Ovarian Follicles
Within the cortex are
thousands of ovarian
follicles.
Several different kinds of
ovarian follicles, each
representing a different
stage of development.
Oogenesis:
maturation of a primary
oocyte to a secondary
oocyte.
36. 28-36
Before Birth
The process of oogenesis occurs in a female fetus
before birth. At this time, the ovary contains
primordial germ cells called oogonia, which are
diploid cells, meaning they have 23 pairs of
chromosomes.
During the fetal period, the oogonia start the process
of meiosis, but they are stopped at prophase I. At
this point, the cells are called primary oocytes.
At birth, the ovary of a female child is estimated to
contain approximately 1.5 to 2 million primordial
follicles within its cortex.
The primary oocytes in the primordial follicles remain
arrested in prophase I until after puberty.
37. 28-37
From Puberty to Menopause
During childhood ovaries are inactive, and no follicles
develop.
Atresia occurs, in which some primordial follicles
regress or break down.
By the time she reaches puberty only about 400,000
primordial follicles remain.
At puberty, the hypothalamus releases GnRH
(gonadotropin-releasing hormone), which stimulates
the anterior pituitary to release FSH (follicle-
stimulating hormone) and LH (luteinizing hormone).
The levels of FSH and LH vary in a cyclical pattern
and produce a monthly ovarian cycle.
The three phases of the ovarian cycle: are the
follicular phase, ovulation, and the luteal phase.
38. 28-38
The Three Phases of the Ovarian Cycle
Follicular phase occupies days 1–13 of an approximate 28-
day ovarian cycle.
Ovulation occurs on day 14 of a 28-day ovarian cycle and is
defined as the release of the secondary oocyte from a
vesicular follicle.
only one ovary ovulates each month
Luteal phase occurs during days 15–28 when the remaining
follicle cells in the ruptured vesicular follicle turn into a
corpus luteum.
secretes progesterone and estrogen that stabilize and
build up the uterine lining, and prepare for possible
implantation of a fertilized oocyte
has a life span of about 10–13 days if the secondary
oocyte is not fertilized
it regresses and becomes a corpus albicans
the uterine lining to be shed as menstruation
menarche
39. 28-39
Regions of the Uterus
Fundus
Body
Isthmus
Cervix
Cervical canal
Internal ostium
External ostium
40. 28-40
Wall of the Uterus
Composed of three concentric tunics:
Perimetrium
Myometrium
Endometrium
The outer tunic of most of the uterus is a serosa called the
perimetrium.
continuous with the broad ligament
The myometrium is the thick, middle tunic of the uterine wall
formed from three intertwining layers of smooth muscle.
in the nonpregnant uterus, the muscle cells are less than
0.25 millimeters in length
during the course of a pregnancy, smooth muscle cells
increase both in size and in number
42. 28-42
The Uterus Serves Four
Functions
Site for implantation.
pre-embryo implants into the inner uterine wall and becomes
connected to the uterine lining
Supports, protects, and nourishes the developing embryo/fetus
forms a vascular connection with the mother’s uterine wall
that later develops into the placenta
Ejects the fetus at birth after maternal oxytocin levels increase
to initiate the uterine contractions of labor.
Site for menstruation.
if an oocyte is not fertilized or after a baby is expelled, the
muscular wall of the uterus contracts and sheds its inner
lining as menstruation
43. 28-43
After Menopause
The time when a woman is nearing menopause is called
perimenopause.
estrogen levels begin to drop, and
a woman may experience irregular periods, skip some periods, or
have very light periods
When a woman has stopped having monthly menstrual
cycles for 1 year and is not pregnant, she is said to be in
menopause.
The age at onset typically is between 45 and 55 years
follicles stop maturing, and significant amounts of estrogen and
progesterone are no longer being secreted
a woman’s endometrial lining does not grow, and she no longer has
a menstrual period
44. 28-44
Uterine Tubes
The uterine tubes, also called the fallopian tubes or oviducts,
extend laterally from both sides of the uterus toward the ovaries.
In these tubes, the secondary oocyte is fertilized, and the pre-
embryo begins to develop as it travels toward the uterus.
Usually it takes the pre-embryo about 5 to 6 days to reach the
lumen of the uterus.
Parts: lined with mucosa (simple ciliated columnar ep),
muscularis, serosa
Infundibulum
Ampulla
Isthmus
Interstitial segment
47. 28-47
Uterine (Menstrual) Cycle and
Menstruation
The menstrual phase occurs approximately during days 1–5
of the cycle. This phase is marked by sloughing of the functional
layer and lasts through the period of menstrual bleeding.
The proliferative phase follows, spanning approximately
days 6–14. The initial development of the functional layer of the
endometrium overlaps the time of follicle growth and estrogen
secretion.
The last phase is the secretory phase, which occurs at
approximately days 15–28. During the secretary phase,
increased progesterone secretion from the corpus luteum
results in increased vascularization and development of uterine
glands.
If the oocyte is not fertilized, the corpus luteum degenerates,
and the progesterone level drops dramatically.
Without progesterone, the functional layer lining sloughs off, and
the next menstrual phase begins.
49. 28-49
Vagina
The vagina is
thick-walled, fibromuscular tube
forms the inferior-most region of the female reproductive tract
measures about 10 centimeters in length in an adult female.
The vagina connects the uterus with the outside of the body
anteroventrally
functions as the birth canal.
Also the copulatory organ of the female
Serves as the passageway for menstruation.
The vaginal wall is heavily invested with both blood vessels and
lymphatic vessels.
The vagina’s relatively thin, distensible wall consists of three
tunics:
an inner mucosa, a middle muscularis, and an outer adventitia
50. 28-50
External Genitalia
The external sex organs of the female, are collectively called the
vulva.
The mons pubis is an expanse of skin and subcutaneous
connective tissue immediately anterior to the pubic symphysis.
covered with pubic hair in postpubescent females
labia majora
labia minora
Contain the vestibule
Urethral orifice
Vaginal orifice
Clitoris located at the anterior regions of the
labia minora
glans
prepuce−an external fold of the labia minora that
forms a hoodlike covering over the clitoris.
51. 28-51
Development
The reproductive organs are developed from the
intermediate mesoderm. The permanent organs
of the adult are preceded by a set of structures
which are purely embryonic, and which with the
exception of the ducts disappear almost entirely
before the end of fetal life. These embryonic
structures are the Wolffian and Müllerian ducts,
also known as mesonephric and
paramesonephric ducts, respectively. The
Wolffian duct remains as the duct in males, and
the Müllerian as that of the female.
52. 28-52
Development of male gonads
From indifferent primordia develops
seminiferous tubules, which connects to the
mesonephros and its duct to form semen
transporting pathways. The mesonephric
duct eventually transforms into the ductus
deferens while the paramesonephric duct
disappear.
53. 28-53
Development of female gonads
The primordia tissue differentiates into
the cortex and medulla. Each ovary
contains approximately 1 million of
primordial cells. Each oogonium
surrounded by a single layer of
epithelial cells forms a primary follicle.
54. 28-54
Descent of the gonads
The gonadal primordia appear at the
level of L4-L5. However, neither ovaries
nor testes remain at the place of origin
but descend caudally.
By the 3rd
month of development, the
testis reaches the pelvic cavity and by
the 7th
month – the deep inguinal ring.
60. 28-60
Congenital anomalies:
Epispadias: Urethral opening on
the dorsum of the penis.
Hypospadias: Urethra opens on
the ventral aspect of the penis or
scrotum.
Exstrophy of bladder with
epispadias.
Micropenis.
Bifid penis & double penis:
Occurs if the genital tubercle splits.
EpispadiassHypospadias
Hypospadias Exstrophy & Epispadias