Myleoid Erthrocyted

1. Where did Red Blood Cells originate
from and What is their particular function
in the body?
Roles, Function of Mature RBCs and Immunological Facts
from Greek, erythros for "red" and
kytos for "hollow vessel", with -cyte
translated as "cell" in modern usage
Hemoglobin delivery, circulate miles
through the peripheral circulations
Carries nutrients, hormone and
delivery to organs and tissues, also
carries waste, such as CO2 and takes
to lung to be expelled from body.
Squeezes through threadlike splenic
sinuses and capillaries
Must Maintain Osmotic balance
Hemoglobin chainsLaboratory Information
4-Sickle cell
Sickle Cell Anemia:
 HbS
 Form tactoids with hypoxic stress
 Reversible: half moon shaped, no
pointed projections
Irreversible: Crescent shaped, pointed
projections
MEGALOBLASTIC ANEMIA:
 MCV>100fl
 Megaloblastic RBC precursors are
larger
 Cytoplasm very basophilic
 Asynchrony between nuclear age and
cytoplasmic age
 BM hypercellular
 ME Ratio 1:1 or 1:3
 Low retic count
VIT. B12 or Folic Acid deficiency
IRON DEFICIENCY ANEMIA:
 RBCs smaller, hypochromic
 Decreased RBC count,Hgb, Hct,
MCV,MCHC
 Increased RDW
 Decreased serum Iron, Ferritin,
Transferrin % Saturation
Increased TIBC
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References List
Abnormal Red Blood Cell Conditions
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