Renal biopsy is a procedure to obtain small pieces of kidney tissue for examination under a microscope. It provides valuable information about kidney disease by determining the cause, severity, and best treatment. Indications for renal biopsy include nephrotic syndrome, kidney disease with a systemic condition, acute kidney failure, and in renal transplants. Complications can include bleeding, pain, and fistula formation, but are generally rare. The biopsy results help establish a diagnosis and guide management of kidney disorders.
It is a procedure where small piece of liver tissue is removed and examined to Confirm clinical diagnosis, and assess the severity, and progression treatment response of the disease.
It is a procedure where small piece of liver tissue is removed and examined to Confirm clinical diagnosis, and assess the severity, and progression treatment response of the disease.
It is the removal of solutes and water from body across a semipermeable membrane (dialyzer)
care during and after the dialysis is very important to prevent the entry of pathogens in to the body.
Colonoscopy is a procedure used to see
inside the colon and rectum. Colonoscopy can detect inflamed tissue, ulcers,
and abnormal growths. The procedure is used to look for early signs of
colorectal cancer and can help doctors diagnose unexplained changes in bowel
habits, abdominal pain, bleeding from the anus, and weight loss.
NIDDK
COLONOSCOPY- A PICTORIAL OVERVIEW
• Dear viewers,
• Greetings from “Surgical Educator”
• This week I have uploaded a video on Colonoscopy- the Lower GI Endoscopy.
• In this episode, I showed only the colonoscopic features of common pathologies in colon and rectum.
• I restricted my talk to the essential minimum that an undergraduate medical student must know about the Colonoscopy.
• I discussed about the diagnostic and therapeutic procedures you can do with the Colonoscopy.
• I hope it would be interesting and very useful to all my viewers.
• You can access this video in the following links:
• surgicaleducator.blogspot.com youtube.com/c/surgicaleducator
• Thank you for watching the video.
Peritoneal dialysis is a treatment for kidney failure that uses the lining of your abdomen, or belly, to filter your blood inside your body. Health care providers call this lining the peritoneum. A more convenient method of dialysis in home itself.
It is the removal of solutes and water from body across a semipermeable membrane (dialyzer)
care during and after the dialysis is very important to prevent the entry of pathogens in to the body.
Colonoscopy is a procedure used to see
inside the colon and rectum. Colonoscopy can detect inflamed tissue, ulcers,
and abnormal growths. The procedure is used to look for early signs of
colorectal cancer and can help doctors diagnose unexplained changes in bowel
habits, abdominal pain, bleeding from the anus, and weight loss.
NIDDK
COLONOSCOPY- A PICTORIAL OVERVIEW
• Dear viewers,
• Greetings from “Surgical Educator”
• This week I have uploaded a video on Colonoscopy- the Lower GI Endoscopy.
• In this episode, I showed only the colonoscopic features of common pathologies in colon and rectum.
• I restricted my talk to the essential minimum that an undergraduate medical student must know about the Colonoscopy.
• I discussed about the diagnostic and therapeutic procedures you can do with the Colonoscopy.
• I hope it would be interesting and very useful to all my viewers.
• You can access this video in the following links:
• surgicaleducator.blogspot.com youtube.com/c/surgicaleducator
• Thank you for watching the video.
Peritoneal dialysis is a treatment for kidney failure that uses the lining of your abdomen, or belly, to filter your blood inside your body. Health care providers call this lining the peritoneum. A more convenient method of dialysis in home itself.
FUNDAÇÃO DO ABC Santo André - SP Disciplina de Urologia Faculdade de Medicina ABC 2008
Marcos Tobias Machado Setor de Uro-oncologia BIÓPSIA RENAL: QUANDO INDICAR?
random renal tru cut needle biopsy for histopathology
diffuse renal parenchymal disease and disorders
indications
technique
complications
contraindications
Introduction: Endoscopic RetrogradeCholangiopancreatography (ERCP) has been advocated as a less invasive therapeutic
intervention for the diagnosis and management of various pancreaticobiliary diseases in the aging population. However, the procedure is not without risk. Published literatures have shown different adverse outcomes with the oldest patient documented to be at 97-years-old. This case report of a 99 years and 107 days old male is probably one of the oldest to be recorded to undergo ERCP worldwide, hence is a vital addition to current practice.
Endocuff-Assisted Colonoscopy Demonstrates High Ileal Intubation and Adenoma ...JohnJulie1
The Endocuff (EC) significantly improves the Adenoma Detection Rate (ADR). Whereas cecal intubation and cost-effectiveness using the EC have been studied repeatedly, evidence regarding the Ileum Intubation Rate (IIR) remains scarce. This study investigates the IRR and ADR in EC-assisted colonoscopy compared with standard colonoscopy in patients undergoing screening and/or surveillance colonoscopy.
This is a presentation carried out during one of the Masters Urology classes at the University of Nairobi on Monday 27th April 2020 betweeen 0830-1030 hours. The online session had a maximum of 75 participants.
Contrast induced nephropathy (CIN) is agenerally reversible form of acute kidney injury (AKI) that occurs soon after the administration of radiocontrast media.
Struggling with intense fears that disrupt your life? At Renew Life Hypnosis, we offer specialized hypnosis to overcome fear. Phobias are exaggerated fears, often stemming from past traumas or learned behaviors. Hypnotherapy addresses these deep-seated fears by accessing the subconscious mind, helping you change your reactions to phobic triggers. Our expert therapists guide you into a state of deep relaxation, allowing you to transform your responses and reduce anxiety. Experience increased confidence and freedom from phobias with our personalized approach. Ready to live a fear-free life? Visit us at Renew Life Hypnosis..
We understand the unique challenges pickleball players face and are committed to helping you stay healthy and active. In this presentation, we’ll explore the three most common pickleball injuries and provide strategies for prevention and treatment.
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
How many patients does case series should have In comparison to case reports.pdfpubrica101
Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop.
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CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
1. Renal biopsy
Dr. Kamal Okasha MD. PhD;
Prof of Int Med & Nephrology, Tanta University,
Egypt.
Member of ESNT, ASN, ISN and ERA-EDTA.
Fellowship of Nephrology, Sask University,
Canada.
3. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
For more than 50 years, renal biopsy has been
an important diagnostic procedure in modern
nephrology.
Increasing perfection of the biopsy technique has
made the procedure very safe, with rare
complications and few contraindications.
Ther Umsch. 2002 Mar;59(3):110-6.
INTRODUCTION
4. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Definition: a procedure that is used to obtain
small pieces of kidney tissue to look at under a
microscope.
It may be done to determine:
Cause;
Severity.
Treatment of a kidney disorder.
The procedure is generally safe and can provide
valuable information about kidney disease.
INTRODUCTION
5. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Why?
A renal biopsy is obtained for a number of reasons:
Establishment of the exact diagnosis to determine the
nature of recommended therapy.
Ascertain the degree of active (ie, potentially reversible)
and chronic (ie, irreversible) changes.
The degree of active or chronic changes helps determine
prognosis and likelihood of response to treatment.
In addition, kidney biopsy can be performed to help assess
genetic diseases.
INDICATIONS FOR RENAL BIOPSY
6. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Four groups of patients benefit from the findings
of renal biopsy:
Nephrotic syndrome,
Renal disease in a context of systemic disorder,
Acute renal failure and
Renal transplant.
Some patients with non-nephrotic proteinuria,
hematuria and chronic renal failure may also
benefit from the procedure.
INDICATIONS FOR RENAL
BIOPSY
7. Contraindications
Absolute contraindications
Patient Refusal
Bleeding diathesis
Uncontrolled severe
hypertension
Uncooperative patient
Presence of a solitary
native kidney
Relative contraindications
Azotemia
certain anatomical
abnormalities of the kidney
skin infection at the desired
biopsy site
Hemostasis-altering drugs
(e.g. warfarin or heparin)
pregnancy
urinary tract infections
obesity.
8. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Preparation:
Before your biopsy, patients may need testing to see
if they have a blood clotting abnormality or infection.
To decrease the risk of bleeding, patients should be
asked to stop taking medicines that increase the risk
of bleeding (such as aspirin, aspirin-like compounds,
antiplatlets and anticoagulats) for one to two weeks
before the biopsy.
RENAL BIOPSY PROCEDURE
9. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Biopsy procedure
Renal biopsy is usually performed while patients are
awake, after a cleansing agent is applied, and local
anesthesia is given to minimize pain.
The most common way to perform a biopsy is to use a
needle, which is inserted through the skin and into the
kidney.
Approach is either by using an ultrasound, x-ray, or
CT scan guidance to localise the right position of the
kidney (usually the lower pole)
Biopsy procedure
10. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Once the needle is in the right position, a sample
of renal tissue will be taken with the needle.
In some cases, a different approach is used to
perform the biopsy. An open renal biopsy under
general anesthesia, and a small incision of the
skin and underlying tissue, which is opened to
obtain the kidney specimen.
11. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
After an open or needle biopsy, patient will be
kept in a recovery or an observation unit for
several hours to monitor for potential
complications, including pain and bleeding.
Patients may have blood drawn for cbc or repeat
x-rays to monitor for bleeding.
In some instances, patient will be sent home
after several hours of monitoring. Alternatively,
may be observed in the hospital overnight.
After renal biopsy
12. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Once it is deemed safe for the patient to go
home, he is not allowed to perform any heavy
lifting or vigorous exercise for one to two weeks.
Continue to avoid aspirin-like drugs or blood
thinning medications for at least one week or
until your physician has instructed you that it is
safe to take these.
Instructions after renal biopsy:
13. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
The routine evaluation of a percutaneous renal
biopsy involves examination of the tissue under
LM, IMF, and EM.
Full clinical data and lab tests must be clearly
mentioned in the pathology request you sent to
the renal pathologist.
After renal biopsy
14. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Serious complications of renal biopsy are not
common.
Less serious complications can occur, and
can include bleeding, pain, and development of
an abnormal connection between two blood
vessels (a fistula).
Rare complications include infection, damage
to blood vessels or other organs, or urine leaks.
RENAL BIOPSY COMPLICATIONS
15. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Bleeding is the most common complication of
renal biopsy.
Many people may notice blood in their urine for several days
after a renal biopsy.
More severe bleeding occurring around the kidney or into
the urine is uncommon but if it occurs you may need a blood
transfusion.
Very rarely, it may become life threatening and possibly
require a procedure or surgery to stop the bleeding.
If the urine is bright red or brown for longer than one week
after your biopsy, FUP is needed.
Bleeding
16. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Pain is a common problem after a renal biopsy.
Patient may need pain killers to reduce pain post procedure.
Pain usually resolves within a few hours.
If severe or prolonged pain, most propably renal
hematoma.
Pain
17. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
The biopsy needle can accidentally injure the walls
of a nearby artery and vein, and this can lead to
the development of a fistula. Fistulas generally do
not cause problems and usually close on their own
over time.
Arteriovenous fistula
18. ESNT-CNE 1st Course Cairo Sept 10-14, 2012
Mendelssohn D, Cole E (October 1995). "Outcomes
of percutaneous kidney biopsy, including those of
solitary native kidneys.". Am J Kidney Dis 26 (4):
580–585.
Whittier L, Korbet S (November 2004). "Renal
biopsy: update". Current Opinion in Nephrology and
Hypertension 13 (6): 661–665.
Iversen P, Brun C (September 1951). "Aspiration
biopsy of the kidney". Am. J. Med. 11 (3): 324–30.
References