A presentation given during the orientation day (Sept 11, 2011) for UQUDENT students to go through the different learning resources at Umm Al-Qura University.
Describe the major available electronic resources
Describe how to build a search strategy
Describe some alternate sources for finding trials
Describe what to do once you get your search results
This presentation was funded by CDC and PEPFAR through the SUCCEED project at Stellenbosch University. The presentation was delivered by Ms Lynn Hendricks from the Centre for Evidence Based Health Care in July 2017
A presentation given during the orientation day (Sept 11, 2011) for UQUDENT students to go through the different learning resources at Umm Al-Qura University.
Describe the major available electronic resources
Describe how to build a search strategy
Describe some alternate sources for finding trials
Describe what to do once you get your search results
This presentation was funded by CDC and PEPFAR through the SUCCEED project at Stellenbosch University. The presentation was delivered by Ms Lynn Hendricks from the Centre for Evidence Based Health Care in July 2017
Module 2 of the Oral Health Tutorial, a production of UT HSC Libraries.
This module focuses on evidence-based dental health. View this tutorial to learn how to define evidence-based dental public health, learn effective retrieval strategy, be able to critique the literature and apply it to public health dental practice.
This tutorial is copyright Lara Sapp and Julie Gaines.
Janet Schnall's presentation about Evidence Based Nursing Resources at our free monthly webcast. Recording available at https://webmeeting.nih.gov/p96958659/
"Hierarchies of Evidence" is an important but problematic concept for medical professionals to understand as it underpins their capacity to be effective practitioners and researchers.
Module 2: Evidence-Based Dental Public HealthKelley Minars
The updated version of this tutorial is available here: http://www.slideshare.net/uthsclib/module-2-evidencebased-dental-public-health-1724938
Module 2 of the Oral Health Tutorial, a production of UT HSC Libraries.
This module focuses on evidence-based dental health. View this tutorial to learn how to define evidence-based dental public health, learn effective retrieval strategy, be able to critique the literature and apply it to public health dental practice.
This tutorial is copyright Lara Sapp and Julie Gaines. Uploaded with permission.
Introduce IUON students to evidence-based nursing literature and effective strategies for searching for and accessing evidence-based research in nursing.
This ppt will help dentists in taking Evidence Based decision in daily practice and will also help researchers to categorized result of research on the basis of hierarchy of Evidence Based Dentistry
PHAR1101: Broadening Search in OneSearchLucia Ravi
This presentation aims to support PHAR1101 students in searching for general resources about their Drug Pioneer within the UWA Library OneSearch catalogue.
PsychINFO database searching, gender dysphoria 2017Lucia Ravi
A basic introduction to constructing a simple search within the the PsycINFO Database on the Ovid platform. Sample search on "Gender Dysphoria" as a topic created for the IMED1108, Sem2, 2017.
HealthMed Complete database searching, female fetus 2017Lucia Ravi
A basic introduction to constructing a simple search within the Health and Medical Complete Database. Sample search on "Female fetus" as a topic created for the IMED1108, Sem2, 2017.
Scopus database searching, topic or author search Aug2017Lucia Ravi
A short introduction to Scopus - one of the specialist citation tracking database provided through the UWA Library. Provides tips for constructing a topic and author search in Scopus and running some of the analysis reporting features availalbe.
This presentation will introduce you to the basics of starting a search in UWA's OneSearch catalogue.
It was created by the UWA Library to support student's researching for their IMED1108 assessment.
DENT4104 Searching Medical Databases for EvidenceLucia Ravi
This slideshare is from a lecture given to DENT4104 students beginning UWA's Doctor of Medical Dentistry. It introduces a number of specialist databases that collate high level evidence based medical resources such a practice guidelines, systematic reviews and studies.
This slideshare is from a lecture given to DENT4104 students beginning UWA's Doctor of Medical Dentistry. It introduces some basis OneSearch Library catalogue functions and introduces the notion of Evidence Based Practice.
Drug Pioneer Research - Broadening your search in OneSearchLucia Ravi
Research tips to support students in PHAR1101 to complete their Drug Pioneer Research project. This presentation focuses on using OneSearch, the UWA Library catalogue to broaden their search and to manage their results.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Telegram: bmksupplier
signal: +85264872720
threema: TUD4A6YC
You can contact me on Telegram or Threema
Communicate promptly and reply
Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
1. Finding Empirical
Evidence
PUB5754 – Clinical Epidemiology
Finding Empirical
Evidence
PUB5754 – Clinical Epidemiology
Lucia Ravi
Librarian
Medical and Dental Library
Lucia Ravi
Librarian
Medical and Dental Library
2. Research Purpose
Develop a health promotion review that addresses a core
risk factor associated with NCD’s using empirical evidence
•Impact and consequence of the health risk factor in Australia
(500 words)
•Known causes of the risk factor and population burden based
on review papers (1200 words)
•Summary of known preventative actions - focus no more then 4
intervention strategies using high level EBP (1800 words)
Assessment Summary:
3. Research Skills
– Construct an effective search strategy
– Know what types of medical resources are
available and how to search them
– Understand the different levels of hierarchies
of evidence available to them;
– focus your search strategy on high level,
synthesised sources of evidence
Relevant Search Skills:
4. Search Strategy
Risk Factor: impact, causes, context in Australia
Identifying key concepts, terms:
Unhealthy Eating Impact Australia
“poor diet” causes
consequences
reasons
Western Australia
WA
5. Search Strategy
Risk Factor: impact, causes, context in Australia
Adding Boolean logic, truncation and phrases:
“Unhealthy Eating”
OR
Impact
OR
Australia
OR
“poor diet”
Nutrition
Obesity
Obes*e/ity
causes
consequences
Reason*s
epidemiology
Etiology
Western Australia
WA
Austral* ia, ian, s
• Use quotations “…….” to search for a phrase
• Use asterix * to find all term derivatives
• Use OR to search for/identify all similar concepts
• Use AND to combine concepts and identify results that include both
AND
AND
6. Boolean Logic
AND retrieves all the articles with both
‘Diabetes’ and ‘Indigenous’
OR retrieves all the articles containing either
‘Aboriginal’ or ‘Indigenous’ or both
NOT retrieves all the articles containing
‘Indigenous’ but not those about
‘Canada’
7. Search Tips
Phrases and Truncation:
smok* = smoke, smoker, smoking
Austral* = Australia, Australian, Australians,
Australasian
4. Use Quotation Marks for Phrases
“cigarette smoking”
8. Search Strategy
Constructing a search string
(“unhealthy eating” OR “poor diet” OR obes*)
AND
(“austral*)
AND
(impact OR cause* OR epidemiology OR etiology OR
aetiology)
In most databases enclosing terms in brackets will help order
how concepts will be searched.
10. Search Tips Grey Literature
Have a go:
Search one of the sources
•AIHW
•ABS
•WHO
Identify one possible item
Share with a neighbour
YouTube Link
11. Research Purpose
Develop a health promotion review that addresses a core
risk factor associated with NCD’s using empirical evidence
•Impact and consequence of the health risk factor in Australia
(500 words)
•Known causes of the risk factor and population burden based
on review papers (1200 words)
•Summary of known preventative actions - focus no more then 4
intervention strategies using high level EBP (1800 words)
Assessment Summary:
12. Search Databases
Australian Context
Have a go:
Search one of the sources
•AUSTHealth
•Heath & Medical
Complete
•CINAHL Plus
Identify one possible item
Save or send an item
Share with a neighbourYouTube Link
14. Hierarchy of Evidence
The hierarchy of evidence is:
•A hierarchy of the likely best evidence
•Designed to be used as a shortcut by busy
clinicians and researchers to find the best evidence
•Assists researchers to conduct their own rapid appraisal
University of Oxford, Centre for Evidence Based Medicine. (2011). The 2011 Oxford CEBM levels of evidence: introductory
document. Retrieved from:
http://www.cebm.net/wp-content/uploads/2014/06/CEBM-Levels-of-Evidence-Introduction-2.1.pdf
17. Evidence Based Guidelines and
Summaries
• Developed by synthesising the highest
level of evidence available
• Provide recommendations supported
by that evidence
• May take into account resources and
practices relevant to the organisation
• Concise and clinically relevant
18. Hierarchy of Evidence
National Health and Medical Research Council. (2009). NHMRC Levels of Evidence and
Grades for Recommendations for Developers of Clinical Practice Guidelines. Retrieved from:
https://www.nhmrc.gov.au/_files_nhmrc/file/guidelines/developers/nhmrc_levels_grades_evidence_120423.pdf
20. Clinical Practice Resources
Have a go:
Search one of the sources
•BMJ Best Practice
•UpToDate
•ClinicalKey
Share with a neighbour
Clinical Practice YouTube Link
21. Search Systematic Review
Databases for Interventions
Have a go:
Search one of the sources
•Cochrane
•Medline
•Embase
•PsychInfo
Save searches and items
Share with a neighbour
YouTube Link
22. Contact the University Library
http://library.uwa.edu.au
9346 7570 – Medical and Dental Library
medref-lib@uwa.edu.au
http://facebook.com/UWALibrary
@UWALibrary
Editor's Notes
Hi,
My name is ……… and I’m one of the Science Librarians at the Barry J Marshall Library.
Stress the importance in research of always having your research question in mind.
Some important points about the requirements of this assessment (and research)
Having decided on the health risk area you are to focus on you need to be able to discuss its impact and consequence here in Australia (I will give you some tips on this)
Second point is asking you to expand more on the known causes, how they impact different populations.. again most relevant here in Oz, if your promotional review is targeting an Australia audience but perhaps more too as based on high level reviews.. (As you search and you may need to think about ways you limit to demographics, or etiology (the cause, set of causes, or manner of causation of a disease or condition.) or epidemiology (the branch of medicine which deals with the incidence, distribution, and possible control of diseases and other factors relating to health).
Third point – shift from context and causes to interventions – (ask who knows what EBP stands for – Evidence based Practice – referring to evidence higher in the levels of hierarchy – show of hands familiarity with these concepts – assure will cover briefly and show where further resources can be found)/
This workshop will focus on developing these research skills so as to support you in answering the questions about your risk factor for your promotional review.
Be able to identify and effectively search a range of medical/health resources to locate information relevant to addressing each of the review requirements.
Construct an effective search strategy
Know what types of resources are available and how to search them
Understand that search results will deliver different levels of evidence and focus their search strategy on high level, synthesised sources of evidence.
Understand the different levels of hierarchies of evidence available to them;
Have strategies for limiting to and evaluating these
Before you start any search, it’s important to spend a little bit of time:
Breaking down your search topic identifying the core concepts important to your research,
Coming up with other keywords/terms used to describe your topic and thinking about how you combine them.
Other terms you could add:
Nutrition
Obesity
For impact:
Do you know of any medical terms that could help:
Epidemilogy – study of the distribution and determinants of health related states or events
Aetiology
It is worth putting some thought into what your concepts are and how you might
Before you start any search, it’s important to spend a little bit of time:
Breaking down your search topic identifying the core concepts important to your research,
Coming up with other keywords/terms used to describe your topic and thinking about how you combine them.
Other terms you could add:
Nutrition
Obesity
For impact:
Do you know of any medical terms that could help:
Epidemilogy – study of the distribution and determinants of health related states or events
Aetiology
It is worth putting some thought into what your concepts are and how you might
Remember our boolean logic terms? What are they?
Note: the NOT excludes items containing both ‘indigenous’ and Canada – potentially relevant results? Use NOT with caution, generally for refining a search only or for multiple meanings of the same word, eg China (country) vs china (porcelain).
Use the truncation symbol (usually an asterisk) to broaden your search.
Explain Boolean and Brackets.
Explain that you use broad terms at this early stage, can increase specificity if retrieving too many results.
Would not necessarily use all of the terms developed, you are starting a process of seeing which work best in the different resources we will search.
Who is familiar with the term Grey Literature and can tell me what it is?
Often used to refer to government or non-government, organisation or agency sources of information (reports, data etc) that are gathered by them and that may not otherwise be able to be located in bibliographic databases which have as their greater focus published items such as books, articles and research… sometimes reports are captured in some databases.
Can represent the most direct route to information about a specific population, especially in a country like Australia.
Population health guide: Statistics, reports and website page:
Explain what a subject guide is and what it is.. Direct to the guide and to search for their specific risk factor…
Example:
Example: View Subject, Publication and Data tab to see if there is information on your topic OR try searching your terms within a website
Stress the importance in research of always having your research question in mind.
Some important points about the requirements of this assessment (and research)
Having decided on the health risk area you are to focus on you need to be able to discuss its impact and consequence here in Australia (I will give you some tips on this)
Second point is asking you to expand more on the known causes, how they impact different populations.. again most relevant here in Oz, if your promotional review is targeting an Australia audience but perhaps more too as based on high level reviews.. (As you search and you may need to think about ways you limit to demographics, or etiology (the cause, set of causes, or manner of causation of a disease or condition.) or epidemiology (the branch of medicine which deals with the incidence, distribution, and possible control of diseases and other factors relating to health).
Third point – shift from context and causes to interventions – (ask who knows what EBP stands for – Evidence based Practice – referring to evidence higher in the levels of hierarchy – show of hands familiarity with these concepts – assure will cover briefly and show where further resources can be found)/
Example: View Subject, Publication and Data tab to see if there is information on your topic OR try searching your terms within a website
This pyramid represents the hierarchy of evidence that can be used to answer clinical questions. It will help lead you to the best resources where you can find evidence for your question. The higher the level of evidence (clinical importance) the less information out there for you to find. Higher levels of evidence are problem focused.
In your exploration of EBP and hierarchies of evidence you may come across slightly different hierarchies, this is the UWA FMDHS endorsed hierarchy of evidence.
This pyramid represents the hierarchy of evidence that can be used to answer clinical questions. It will help lead you to the best resources where you can find evidence for your question. The higher the level of evidence (clinical importance) the less information out there for you to find. Higher levels of evidence are problem focused.
In your exploration of EBP and hierarchies of evidence you may come across slightly different hierarchies, this is the UWA FMDHS endorsed hierarchy of evidence.
More information about the hierarchy: The bottom layer of the main hierarchy – single studies – has its own hierarchy depending on the original type of study performed.
Systematic Reviews aim to– use a transparent process to identify, appraise, and summarise studies in relation to a defined clinical question.
They summarise a particular set of similar studies often focused on a particular intervention , but they are not a survey of available evidence. They may or may not include a meta-analysis. The final report will include their search strategies, keywords, subject headings.
EB Guidelines: use evidence drawn from systematic reviews and studies. Problem focussed.
EB Summaries: drawn on systematic reviews or the best available primary studies to integrate the highest level of available evidence and thereby provide a full range of management options for your given problem.
You will not find any decision support systems – because the problem they consider is so focussed. But the library provides access to a range of resources covering the other levels of the pyramid.
This pyramid represents the hierarchy of evidence that can be used to answer clinical questions. It will help lead you to the best resources where you can find evidence for your question. The higher the level of evidence (clinical importance) the less information out there for you to find. Higher levels of evidence are problem focused.
In your exploration of EBP and hierarchies of evidence you may come across slightly different hierarchies, this is the UWA FMDHS endorsed hierarchy of evidence.
Shown them how to navigate to this Guide from the UWA website.
Library’s guide to resources for answering clinical questions. The second tab in the guide that you can see here lists EBP resources available through the library catalogue, and tells which level of evidence you will find within.
You can see a table of different resources we have, and the level of evidence you can find in each. The green button next to each connects to a database-specific guide that lists tips for searching, tips on how to broaden or narrow your search, the best clinical use of the information, and positives and negatives of that particular resource. Includes tips on how to broaden your search and how to narrow your search, and tips on using truncation and wildcards.
Example: View Subject, Publication and Data tab to see if there is information on your topic OR try searching your terms within a website
Example: View Subject, Publication and Data tab to see if there is information on your topic OR try searching your terms within a website