This document provides an overview of evidence-based nursing practice and how to effectively search for and evaluate evidence. It defines evidence-based practice as using the best available evidence from research to improve clinical practice. A 5-step process is outlined: formulating a question, searching literature, critically appraising evidence, applying evidence to practice, and re-evaluating. Guidance is given on formulating search strategies using PICO and searching various library databases and resources like Cochrane and CINAHL to find relevant evidence to answer clinical questions.