This document summarizes a study on mirror gazing behaviors in people with Body Dysmorphic Disorder (BDD). The study found that those with BDD had different motivations, behaviors, and outcomes from mirror gazing compared to controls. Specifically:
1) BDD patients were more motivated by a desire to see themselves differently or know exactly how they look.
2) They focused more on internal feelings about their appearance rather than their external reflection.
3) BDD patients felt worse after mirror gazing and were more likely to use ambiguous reflective surfaces beyond mirrors.
The study provides insights into problematic mirror gazing behaviors that are treatment targets for BDD.
Body dysmorphic disorder (BDD), also known as body dysmorphia, body dysmorphia disorder and BDD disorder, is a mental health condition in which people suffer acute distress in response to perceived physical flaws.
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Body dysmorphic disorder (BDD), also known as body dysmorphia, body dysmorphia disorder and BDD disorder, is a mental health condition in which people suffer acute distress in response to perceived physical flaws.
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Personality disorder are a group of mental health conditions that are characterized by inflexible and atypical patterns of thinking, feeling, and behaving.
Media Information Please take a few moments to peruse our brief presentation. Our intention is to enable a better understanding of Study-International, of what we offer our partners and to underline our focus in recruiting students for you.Thank You.Dan Billington Founder & Director Study-International Ltd
Personality disorder are a group of mental health conditions that are characterized by inflexible and atypical patterns of thinking, feeling, and behaving.
Media Information Please take a few moments to peruse our brief presentation. Our intention is to enable a better understanding of Study-International, of what we offer our partners and to underline our focus in recruiting students for you.Thank You.Dan Billington Founder & Director Study-International Ltd
Accommodative esotropia is one of the most frequently encountered forms of strabismus (eye turn). This presentation reviews information on its causes, diagnosis and treatment.
Convergence insufficiency is one of the most frequently encountered binocular vision problem in children and adults. It is often associated with a variety of symptoms, including eyestrain, headaches, blurred vision, diplopia [double vision], sleepiness, difficulty concentrating, movement of print while reading, and loss of comprehension after short periods of reading or performing close activities. Have your doctor diagnose and treat this significant visual problem.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS
bdd =)
1. MIRROR, MIRROR ON THE
WALL, WHO’S THE UGLIEST
OF THEM ALL ?
- The psychopathology of mirror gazing in
body dysmorphic disorder
- David Veale and Susan Riley
2. Body dysmorphic disorder (BDD) is a serious illness when a
person is preoccupied with minor or imaginary physical flaws, usually
of the skin, hair, and nose.
A person with BDD tends to have cosmetic surgery, and even if
the surgeries are successful, does not think they are and is unhappy
with the outcome.
WHAT IS BODY
DYSMORPHIC DISORDER?
3. MIRROR GAZING AND BDD
Mirror gazing occurs in about 80% of patients
with BDD while the remainder tend to avoid
mirrors sometimes by covering them or removing
them to avoid the distress of seeing their own image
and the time wasted mirror gazing.
4. CAUSES OF BDD
The causes of Body Dysmorphic Disorder are
different for each person, usually a combination
of biological, psychological, and environmental
factors. Furthermore, mental and physical abuse,
and emotional neglect, are life-experiences that can
contribute to a person developing BDD.
5. SOME COMMON SYMPTOMS OF
BDD:
Suicidal ideation.
Anxiety; possible panic attacks.
Chronic low self-esteem.
Feeling self-conscious in social environments; thinking that
others notice and mock their perceived defect(s).
Strong feelings of shame.
Avoidant personality: avoiding leaving the home, or only
leaving the home at certain times, for example, at night.
6. METHOD:
52 patients with BDD who reported mirror gazing to
be a feature of their problem were recruited to
complete a “Mirror gazing questionnaire”
A group of 55 controls were recruited from personal
contacts to provide a comparison. The groups were age
and sex matched
7. METHOD..
A pilot study revealed that there were two types of mirror
gazing :
I. A long session was defined as the longest time during the
day that the person spends in front of a mirror. An example was
given of getting ready for the day
II. The remainder of the mirror sessions consisted of shorter
sessions during the day.
8. PROCEDURE:
Subjects were given a self-report mirror gazing questionnaire.
The instructions informed them that we were interested in the
feelings that they had in front of a mirror during the past
month.(deception)
The subject was first asked if he or she had a long session in
front of a mirror on most days of the past month.
9. PROCEDURE..
If the respondent said they had at least one long session in
front of a mirror, then they were asked a series of questions
about a typical long session in front of a mirror.
The same questions were repeated for a typical short
session in front of a mirror and gave an example of checking
their appearance.
10. SUBJECT WERE
TESTED UPON:
Subject were tested upon:
1) Length of time mirror gazing
Subjects were asked:
(a) The average duration of a “long” session in minutes (during the last
month).
(b) The estimated maximum amount of time on any one occasion that he
or she had spent in front of a mirror in hours/minutes.
(c) The average duration (in minutes) and the frequency of a short
session in front of a mirror during the last month
11. SUBJECTS WERE TESTED
UPON
2) Motivation before looking in a mirror
3) Focus of attention
Subjects were asked the location of their concentration in front
of a mirror for both short and long sessions.
They were presented with a 9 point visual analogue scale
between “+4” and “-4”
“-4” represented “I am entirely focused on my reflection in the
mirror” and “+4” represented “I am entirely focused on an
impression or feeling that I get about myself”.
12. SUBJECT WERE
TESTED UPON:
“-4” represented “I am entirely focused on my reflection in
the mirror” and “+4” represented “I am entirely focused on
an impression or feeling that I get about myself”.
13. SUBJECT WERE
TESTED UPON:
4) Distress before and after looking in front of mirror
Subjects were asked to rate the degree of distress on a
visual analogue scale between 1 and 10, “0” represented
“not at all distressed” and “10” was “extremely distressed”.
14. 5) Behavior in front of a mirror
Participants were asked what activities they did in front of a mirror for long and short
sessions and were given a list of options.
They were asked to rate the percentage of time spent on each activity
(a) Trying to hide my defects or enhance my appearance by the use of make-up;
(b) Combing or styling my hair;
(c) Trying to make my skin smooth by picking or squeezing spots;
(d) Plucking or removing hairs or shaving;
(e) Comparing what I see in the mirror with an image that I have in my mind;
(f) Trying to see something different in the mirror;
(g) Feeling the skin with my fingers;
(h) Practising the best position to pull or show in public;
(i) Measuring parts of my face.
15. SUBJECT WERE
TESTED UPON:
6)Type of light preferred
Subjects were asked whether the type of light was important for mirror gazing on a
visual analogue scale between one extreme of “natural day-light” or at the other
extreme of “artificial
light”.
7)Types of reflective surfaces
They were asked if they used a series of mirrors for different profiles or any other
reflective
surface (for example the backs of CDs) for gazing.
16. SUBJECT WERE
TESTED UPON:
8)Mirror avoidance
Subjects were asked if they avoided certain types of
mirrors and the situations in which this occurred.
17. RESULTS:
*Prior to gazing, BDD patients are driven by the hope that they
will look different;
*Bdd patients have the desire to know exactly how they look; a
belief that they will feel worse if they resist gazing and the desire
to camouflage themselves.
*They were more likely to focus their attention on an internal
impression or feeling (rather than their external reflection in the
mirror) and on specific parts of their appearance.
18. RESULT..
*They were also more likely to practise showing the best face to
pull in public or to use “mental cosmetic surgery” to change their
body image than controls.
*BDD patients invariably felt worse after mirror gazing and
were more likely to use ambiguous surfaces such as the backs of
CDs or cutlery for a reflection.
19. CONCLUSION:
BBD patients hold a number of problematic beliefs and
behaviors in their mirror use compared to controls.
Mirror gazing in BDD consists of a series of complex
safety behaviors. It does not follow a simple model of
anxiety reduction that occurs in the compulsive checking
of obsessive–compulsive disorder. The implications for
treatment are discussed.
20. APPLICATION:
*The study has assisted in engaging BDD patients in a model of
“What You See Is What You Construct” as a result of selective
attention to specific aspects of their appearance and on an internal
representation of their body image.
It has introduced the idea of a “response cost” in which the patient
nominates their most hated organization and agrees to pay a sum of
money to it for each check in the mirror but this requires a very
compliant patient.
21. SUGGESTIONS FOR BDD
PATIENTS
1. To use mirrors at a slight distance or ones that are large
enough to incorporate most of their body;
2. To deliberately focus attention on their reflection in the
mirror rather than an internal impression of how they feel;
3. To only use a mirror for an agreed function (e.g. shaving,
putting on make-up) for a limited period of time;
22. 4. To use a variety of different mirrors and lights rather
sticking to one which they “trust”;
5. To focus attention on the whole of their face or body
rather than a specific area;