This document contains summaries of pathology slides from 8 labs examining various organs. Each lab contains 3-4 cases that note the organ, lesions observed on microscopy, and diagnosis. The lesions involve different types of inflammation, including acute, chronic, suppurative, catarrhal, and others. A wide variety of organs are discussed, including lung, heart, blood vessels, brain, stomach, intestine, liver and more. For each case, the specific microscopic findings leading to the diagnosis of a particular inflammatory condition are presented.

1. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
Second Course
By: Rayan Aziz 2017-2018

2. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 1)
By: Rayan Aziz 2017-2018

3. Questions
Organ .....................?
Stain.......................?
Lesion.....................?
Diagnosis................?

4. •LAB: 1 (H&E)
• 1-Organ: Lung
• Lesions: Several infiltration of acute inflammatory cells mainly
neutrophils which occupy or fill part of lung tissue, thickening
of pleura and interstitial septa due to accumulation of
excessive amount of exudates (pus).
• Diagnosis: Suppurtive inflammation
• 2-Organ: Intestine
• Lesions: Enlargement of the secretory epithelial cells of
mucous gland, sloughing of villi, profuse discharge of mucus
and epithelial debris, with infiltration of inflammatory cells.
• Diagnosis: Catarrhal inflammation (catarrhal enteritis)

5. • 3-Organ: Brain
• Lesions: Several infiltration of acute inflammatory cells
(neutrophils) thicking of meningis with pus formation in
the brain, severe congestion.
• Diagnosis: Acute inflammation meningis.
• 4-Organ: Lung
• Lesions: several infiltration of acute inflammatory cells
mainly neutrophils, the alveoli are filled with
inflammatory exudate. Thicking of alveolar wall and
septa.
• Diagnosis: Acute pneumonia.

6. • 5-Organ: Intestine
• Lesions: Inflammatory reaction appears like nodules or
granuloma which consists of chronic inflammatory cells, the
granulomatous reaction surrounded by fibrous connective
tissue in submucosa of intestine.
• Diagnosis: Chronic inflammation (granulomatous enteritis).
• 6-Organ: Lung
• Lesions: Diffuse infiltration of inflammatory cells
(lymphocyte) with severe hemorrhage which occupied all
parts of lung tissue, bronchi, and bronchiole. Severe
damage of lung tissue.
• Diagnosis: Viral inflammation.

7. LAB: 1
(1) Lung
D: Suppurtive inflammation

8. LAB: 1
(2) Intestine
D:Catarrhal inflammation (catarrhal enteritis)

9. LAB: 1
(3) Brain
D:Acute inflammation (Meningitis)

10. LAB: 1
(4) Lung
D:Acute Inflammation

11. LAB: 1
(5) Intestine
Chronic inflammation

12. LAB: 1
(6) Lung
D:Viral inflammation

13. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 2)
By: Rayan Aziz 2017-2018

14. •LAB: 2 (H&E)
• 1-Organ: Cardiac Muscle
• Lesions: Severe infiltration of inflammatory cells between
the muscle fibers (Myocitis) mostly mononuclear
inflammatory cells, fibrosis, odema, congestion, and sever
muscular damage and degeneration.
• Diagnosis: Myocarditis.
• 2-Organ: Artery
• Lesions: thickening of arterial wall due to proliferation of
smooth muscle cells, accumulation of cholesterol cleft
fibrin foamy cells and narrowing of the lumen.
• Diagnosis: Atherosclerosis.

15. • 3-Organ: Cardiac muscles
• Lesions: Focal area of myofibral disarranged associated
with mild infiltration of inflammatory cells and myofibral
degeneration.
• Diagnosis: Cardiomyopathy.

16. LAB: 2
(1) Cardiac muscle
D: Myocarditis

17. LAB: 2
(2) Artery
D: Atherosclerosis

18. LAB: 2
(3) Cardiac muscles
D: Cardiomyopathy

19. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 3)
By: Rayan Aziz 2017-2018

20. •LAB: 3 (H&E)
• 1-Organ: Cardiac muscle
• Lesions: Diffuse of multifocal cardiocyte degeneration and
necrosis. The cardiac muscles appears like mass staining pink
with eosin with loss of all structure, odema, diffuse infiltration
of inflammatory cells.
• Diagnosis: Neutritional cardiomyopathy.
• 2-Organ: Artery
• Lesions: Thickening of the intimal layer of different artery in
same area which consist of dense collagen fiber surrounding
the fibrinoid degeneration. Perivascular accumulation of
inflammatory cells mostly lymphocyte, plasma cells.
• Diagnosis: Polyarteritis.

21. • 3-Organ: Cardiac muscle
• Lesion: Severe infiltration of mononuclear inflammatory
cells mainly lymphocytes between cardiac muscle, severe
congestion.
• Diagnosis: Viral myocarditis.

22. LAB: 3
(1) Cardiac muscles
D: Neutritional
cardiomyopathy

23. LAB: 3
(2) Artery
D: Polyarteritis

24. LAB: 3
(3) Cardiac muscle
D: Viral myocarditis

25. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 4)
By: Rayan Aziz 2017-2018

26. •LAB: 4 (H&E)
• 1-Organ: Lung
• Lesions: Several infiltration of acute inflammatory cells
mainly neutrophils which occupy or fill part of lung tissue,
thickening of pleura and interstitial septa due to
accumulation of excessive amount of exudates (pus).
• Diagnosis: Acute pneomonia.
• 2-Organ: Lung
• Lesions: Diffuse peribronchial infiltration of lymphocytes and
few heterophils. Thickening of the wall of bronchi and the
lumen are filled with sever hemorrhage, and congestion with
diffuse alveolar damage.
• Diagnosis: bronchitis…..Viral bronchitis…..viral pneumonia
…..infectious bronchitis.

27. • 3-Organ: Lung
• Lesions: Sever distraction of alveolar tissue associated with
sever hemorrhage which occupied all part of lung tissue
with sever infiltration of inflammatory cells.
• Diagnosis: Hemorrhagic pneumonia
• 4-Organ: Lung
• Lesions: presence of many discrete nodules as a halo or
granules distributed throughout the lung tissue which
consist of coagulative necrosis, surrounded by zone of
chronic inflammatory cells and connective tissue. Presence
of hyphae as lightened, a radial pattern, sever hemorrhage.
• Diagnosis: Aspargillus pneumonia. (pulmonary
aspargillosis)

28. LAB: 4
(1) Lung
D: Acute pneumonia

29. LAB: 4
(2) Lung
D: Viral pneumonia

30. LAB: 4
(3) Lung
D: Hemorrhagic
pneumonia

31. LAB: 4
(4) Lung
D: Fungal pneumonia

32. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 5) H&E
By: Rayan Aziz 2017-2018

33. •LAB: 5 (H&E)
• 1-Organ: Lung
• Lesions: Sever inflammation of bronchial epithelial cells,
associated with infiltration of leukocyte, dilated of alveoli and
filled with inflammatory cells and exudate, projection of
epithelial cells from bronchi due to hyperplasia.
• Diagnosis: Bronchopneumonia
• 2-Organ: Lung
• Lesions: The pleural layer is infiltrated with inflammatory cells,
thickening of pleura due to odema, inflammatory exudate and
zone of inflammatory cells surrounded the inflammatory area,
capillaries are numerous and greatly dilated.
• Diagnosis: Pleuro pneumonia

34. • 3-Organ: Lung
• Lesions: Mild inflammation, the alveoli filled with serous
exudate which appear as pink in color with H&E, odema
thickening of interstitial septa.
• Diagnosis: Serous pneumonia

35. LAB: 5
(1) Lung
D: Bronchopneumonia

36. LAB: 5
(2) Lung
D: Pleuro pneumonia

37. LAB: 5
(3) Lung
D: Serous pneumonia

38. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 6) H&E
By: Rayan Aziz 2017-2018

39. •LAB: 6 (H&E)
• 1-Organ: Stomach
• Lesions: Thickening of gastric mucosa, sever infiltration of
inflammatory cells between glands and mucosa, congestion of
blood vessels, the mucus gland become tortous and most of
them lined by cuboidal epithelial cells.
• Diagnosis: Acute gastritis.
• 2-Organ: Stomach
• Lesions: Mild inflammatory reaction of mucosa and submucosa
with mild infiltration of inflammatory cells. Gastric mucous
gland become distorted, enlarged, and filled with mucin, as
well as desquamation of gastric epithelium.
• Diagnosis: Catarrhal gastritis.

40. • 3-Organ: Esophagus
• Stain: H&E and Special stain(fungal stain)
• Lesions: presence of fungal hyphae in the superficial epithelial
layer of esophagus necrotic area associated with mild
inflammation with mild infiltration of inflammatory cells
mainly lymphocyte, macrophage, fibrosis.
• Diagnosis: Fungal esophagitis.
• 4-Organ: Intestine
• Lesions: Excessive production of catarrhal exudate, specially
in a villi of intestine, infiltration of inflammatory cells in crypts
and villi. Some of villi and crypts get smaller and congested.
• Diagnosis: Catarrhal enteritis.

41. LAB: 6
(1) Stomach
D: Acute gastritis

42. LAB: 6
(2) Stomach
D: Catarrhal gastritis

43. LAB: 6
(3) Esophagus(Special stain)
D: Fungal esophagitis

44. LAB: 6
(3) Esophagus(H&E)
D: Fungal esophagitis

45. LAB: 6
(4) Intestine
D: Catarrhal enteritis

46. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 7) H&E
By: Rayan Aziz 2017-2018

47. •LAB: 7 (H&E)
• 1-Oragn: Peritoneum
• Lesions: Sever infiltration of inflammatory cells especially in the
epithelial layers of peritoneum, thickening of peritoneum and
sever congestion of blood vessels
• Diagnosis: Peritonitis.
• 2-Organ: Liver
• Lesions: Aever infiltration of inflammatory cells which occupied
all parts of liver tissue, some of them appears as focal area
which consist of different number of inflammatory cells. Sever
congestion of hepatic sinusoids and some of degeneration
changes appear like fatty changes.
• Diagnosis: Acute hepatitis

48. • 3-Organ: Rumen
• Lesions: Sever inflammation which effected all layers of
rumen from mucosa to serosa, most of inflammatory cells are
neutrophil, necrotic changes in submucosa and sever
congestion of blood vessels.
• Diagnosis: Mycotic and bacterial rumenitis.
• 4-Organ: Intestine
• Lesions: Sever infiltration of inflammatory cells mainly
polymorpho nuclear cells, destruction of both villi and crypts
of intestine. Most are inflammated with excessive production
of fibrin, ulceration of muscular layer, presence of thick
diphtheritic membrane, which cover the mucosa and necrosis
of crypt.
• Diagnosis: Diphtheritic enteritis

49. • 5-Organ: Stomach
• Lesions: Presence of different area of ulceration in the
mucosa and submucosa of stomach with mild infiltration of
inflammatory cells and some of this ulceration reach to
muscular layer.
• Diagnosis: Ulcerative gastritis
• 6-Organ: Liver
• Lesions: presence of focal area of cirrhosis, which consist of
degenerative changes, necrosis, hyperplasia with
inflammatory cells. The area of cirrhosis appear as small
nodules surrounded by a zone of fibrous connective tissue.
Fatty changes and hemorrhage .
• Diagnosis: Cirrhosis

50. LAB: 7
(1) Peritoneum
D: Peritonitis

51. LAB: 7
(2) Liver
D: Acute hepatitis

52. LAB: 7
(3) Rumen
D: Mycotic and bacterial rumenitis

53. LAB: 7
(4) Intestine
D: Diphtheritic enteritis

54. LAB: 7
(5) Stomach
D: Ulcerative gastritis

55. LAB: 7
(6) Liver. D: Cirrhosis

56. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 8) H&E
By: Rayan Aziz 2017-2018

57. •LAB: 8 (H&E)
• 1-Organ: Kidney
• Lesions: Inflammation of glomeruli of kidney, which
appears as multiple nodules surrounded by diffuse
infiltration of inflammatory cells. Most of tubules are also
inflammated with degeneration and necrosis
• Diagnosis: Glomerulonephritis
• 2-Organ: Kidney
• Lesions: Presence of small area of suppuration and
necrosis in the cortex of kidney, which surrounded by
different number of inflammatory cells. Degeneration and
necrotic changes of some tubules with presence of cast in
the lumen of tubules.
• Diagnosis: Focal suppurative nephritis.

58. • 3-Organ: Kidney
• Lesion: Interstitial tissue between tubules and glomeruli
area inflammated and infiltrated with number of
inflammatory cells mainly lymphocyte, degenerative and
necrotic changes of tubules and some of tubules are
filled with cast, fibrosis
• Diagnosis: Interstitial nephritis
• 4-Organ: Kidney
• Lesions: Severe infiltration of inflammatory cells of renal
tissue, some of them appear like granular and others are
appear distributed through the kidney hemorrhage,
thrombosis of blood vessels specially around the
glomeruli, severe generative and necrotic change of renal
tissue.
• Diagnosis: Acute nephritis

59. LAB: 8
(1) Kidney
D: Glomerulonephritis

60. LAB: 8
(2) Kidney
D: Focal suppurative nephritis

61. LAB: 8
(3) Kidney
D: Interstitial nephritis

62. LAB: 8
(4) Kidney
D: Acute nephritis

63. PATHOLOGY SLIDES
Organ + Lesion + Diagnosis
(LAB 9)
By: Rayan Aziz 2017-2018

64. •LAB: 9 (H&E)
• 1-Organ: Ovary
• Lesions: Presence of granular cells living the inner layer of cyst.
The outer layer consist of concentrically arranged bands of
connective tissue, middle layer consists of luteal tissue.
Hemorrhage and ulceration, highly infiltration of inflammatory
cells. Necrosis.
• Diagnosis: Oophoritis
• 2-Organ: Ureter
• Lesions: Presence of endometrial gland and stroma between
myometrium. Fibrosis of myometrium, hemorrhage, odema,
hyperplasia of endometrial cells lining of endometrial glands.
• Diagnosis: Endometriosis (intra)

65. LAB: 9
(1) Ovary
D: Oophoritis

66. LAB: 9
(2) Ureter
D: Endometriosis (intra)

67. GOODLUCK
KEEP MOVING
BY: Rayan Aziz 2017 - 2018