Polymers
1
CONTENTS
2
1)Introduction
2)Classification of polymer
3)Properties of polymer
4)Characteristics of ideal
polymer
5)Advantages of polymer
6)Application of polymers in
Pharmacy
INTRODUCTIO
N Polymer is coined from to Greek word “poly” means many
“mer” means parts.
 Defination: polymer is defined as very large molecules
having high molecular mass which are formed by joining
of repeating structural unit on large scale.
 Monomer : repeating structural unit derived from some
simple and reactive moleculeles are linked to each other
by covalent bond.
 Polymerization : process of polymer formation.
Protein, cellulose, resin,
rubber, alginate, gelatin,
albumin.
Nylon , teflon
Polysterylin
Polyethylene,
polypropylene, PLA,
PGA,
Polyhydroxybutyrate ,
Polyanhydride,
Polyacrylamide.
Based on
Sources
Based on polymerization
Based on Degradability
Based on Nature
Based on properties.
Based on structure
Should be inert and compatible with
environment
Should be non toxic
Should be easily administered
Should have good mechanical strength
Should be biodegradable
and biocompatible
Characteristics of ideal
polymer
Advantages of polymer
Localised delivery of drug
Sustained delivery of drug
Decrease in dosing frequency
Reduce side effect
Improve patient compliance
Biodegradable and biocompatible
Disadvantages of polymer
 Exhibit dose dumping effect
 High initial drug release after administration
 Low mechanical properties
Applications
POLYMER APPLICATION
Polyethylene oxide Cosmetic pharmaceuticals
Polyethylene glycol Swelling agent
PVP Tablet granulation
Polyvinyl alcohol Tablet binder and coating
Ethyl cellulose Sustained release system
Carboxy methyl cellulose Super disintegrant
HPMC Coating and binder
15
Application in Drug delivery system
In modified drug release delivery system
Controlled release formulation
Sustained release formulation
Biomedical applications
Tissue engineering
Bone fixation devices
Vaascular graft
Surgical adhesive
Applications
 Industrial Application
 Agriculture Application
 Packaging
Polymers (2)

Polymers (2)

  • 1.
  • 2.
    CONTENTS 2 1)Introduction 2)Classification of polymer 3)Propertiesof polymer 4)Characteristics of ideal polymer 5)Advantages of polymer 6)Application of polymers in Pharmacy
  • 3.
    INTRODUCTIO N Polymer iscoined from to Greek word “poly” means many “mer” means parts.  Defination: polymer is defined as very large molecules having high molecular mass which are formed by joining of repeating structural unit on large scale.  Monomer : repeating structural unit derived from some simple and reactive moleculeles are linked to each other by covalent bond.  Polymerization : process of polymer formation.
  • 5.
    Protein, cellulose, resin, rubber,alginate, gelatin, albumin. Nylon , teflon Polysterylin Polyethylene, polypropylene, PLA, PGA, Polyhydroxybutyrate , Polyanhydride, Polyacrylamide. Based on Sources
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
    Should be inertand compatible with environment Should be non toxic Should be easily administered Should have good mechanical strength Should be biodegradable and biocompatible Characteristics of ideal polymer
  • 12.
    Advantages of polymer Localiseddelivery of drug Sustained delivery of drug Decrease in dosing frequency Reduce side effect Improve patient compliance Biodegradable and biocompatible Disadvantages of polymer  Exhibit dose dumping effect  High initial drug release after administration  Low mechanical properties
  • 13.
  • 14.
    POLYMER APPLICATION Polyethylene oxideCosmetic pharmaceuticals Polyethylene glycol Swelling agent PVP Tablet granulation Polyvinyl alcohol Tablet binder and coating Ethyl cellulose Sustained release system Carboxy methyl cellulose Super disintegrant HPMC Coating and binder
  • 15.
    15 Application in Drugdelivery system In modified drug release delivery system Controlled release formulation Sustained release formulation Biomedical applications Tissue engineering Bone fixation devices Vaascular graft Surgical adhesive
  • 16.
    Applications  Industrial Application Agriculture Application  Packaging