The document provides an extensive overview of polymers, including their definition, classification, and types used in drug delivery systems. It details protein-based polymers, their applications, advantages, and disadvantages, as well as other types like natural, synthetic, and biodegradable polymers. The information is supported by references and includes examples of various polymers with their properties.

1. Presented By,
Mast:- Dhiraj Dilip Malunjkar
M Pharmacy -First Year
Department :- Pharmaceutics
Loknete .Dr. J. D. Pawar College Of Pharmacy ,Manur
POLYMERS

2.  Introduction
 Definition
 Polymerization
 Term Used
 Classification
 Types of polymer used in Drug delivery
 Protein Based polymers
 Applications
 Advantages
 Disadvantages.
CONTENTS

3. Polymers are the large molecules consisting of repeating structural unit called
as “Monomer”.
World ‘Polymer’ Derived Form Greek Greek Word
Poly :- Many
Mer:- Unit Part
They are also referred as macromolecules.
Ex:-
DEFINITION

4. POLYMERIZATION

5. Monomer:-
Small Molecule Which is repeated called as Monomer.
Polymerization:-
It is an chemical reaction in Which Two or more than two molecules
are joined together called polymerization.
Degree Of Polymerization:-
Number of repeating unit (n) in the polymer chain called as Degree
of Polymerization.
it is used to calculate Average molecular weight of polymer.
Average Weight = DP * Weight of repeating unit.
TERM USED

6. CLASSIFICATION

7. 1)Natural Polymer:- Isolated form Natural Materials
Ex. Cotton, Silk , wool, rubber
2)Synthetic Polymer:- Synthesize Form low molecular
weight compound.
Ex . Polyethylene, nylon
3)Semisynthetic Polymer:-Mostly Derived form naturally
Occurring polymer.
Ex .Reyon
BASED ON SOURCE

8. 1)Linear Polymer:-Monomer join form long chain.
Ex . Polyethylene, Nylon.
2)Branched Chain:-Straight long chain with different long chain.
Ex .Polypropylene, amylopectin.
3)Cross Linked:- Two linear chain are joined by covalent bond and having 3D
structure.
Ex .Bakelite , Formaldehyde resins.
BASED ON STRUCTURE

9. 1)Addition Polymerization:-Formed by repeated addition of monomer.
Ex . Polythene.
2)Condensation Polymer:-combination of two monomer by removal of water.
Ex . Nylon 6,6.
BASED ON MODE OF
POLYMERIZATION
Water molecule
removed.

10. 1)Elastomer:-these are rubber – like solid with elastic properties.
Ex .Neoprene.
2) Fibres:-high tensile strength and high modulus.
Ex .Nylon 6,6.
BASED ON MOLECULAR
FORCESES.

11. 1)Crystalline Polymers:-
They not perfectly crystalline structure.
2) Amorphous Polymer:-
they are hard or rubbery state.
BASED ON MORPHOLOGY

12. • Rubber:-
dimensionally unstable
Tensile range 300-1000psi.
• Plastic:-
Stronger than rubber
Tensile range 4000-13000psi.
• Fibres:-
Strongest in different types.
Tensile range20000-150000psi.
BASED ON END USE

13.  Protein Based Polymers:-
• Collagen
• Albumin
• Gelatine
 Polysaccrides:_
• Alginate cychlodextrines
• Chitosan's
• Dextran
 Biodegradable polymers:-
• Polyesters
• Polyunhydried
• Polyamines
• Phosphorous based polymers
 Non- Biodegradable Polymer:-
• Cellulose derivative
• Silicones
• others
Natural polymer Synthetic Polymers
TYPES OF POLYMER USED IN
DRUG DELIVERY

14. 1)Collagen:-
• Major natural protein component in mammals .
• Good Compatible.
• Used in implantation.
2)Gelatine:-
• Water soluble.
• Bio compatible.
• Low antigenicity.
3)Albumin:-
• Cross linked.
• Hydrogels used in materials.
PROTEIN BASED POLYMERS

15.  Alginate:-
• Extracted from seaweed, algae, bacteria.
• Biocompatible
• Biodegradable
• Water soluble
 Dextran:-
• Synthesized form Sucrose.
• Used in protein, vaccine and drugs.
 Starch:-
• Plant origin
• Mostly used.
POLYSACCHARIDES

16. APPLICATIONS

17. ADVANTAGES AND
DISADVANTAGES

18. • Bharde Nilima , Ganesh Godghe , “ADVANCE DRUG DELIVARY
SYSTEM” Tech – Max Publications, Page No:-2-2, 2-56.
• https://www.sciencedirect.com/journal/polymer.
REFERENCE