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Points about drugs sample
The document is a detailed compilation of drug-related topics, covering various classes of drugs such as anticholinesterases, beta blockers, and bisphosphonates. It includes key points about drug mechanisms, therapeutic uses, interactions, and specific conditions requiring particular medications. Additionally, it addresses cataract-related information and complications, showcasing the extensive information on pharmacology and ophthalmology.
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Points about drugs sample
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- 2. POINTS ABOUT DRUGS www.medpgnotes.com 1 Contents ANTICHOLINESTERASE..................................................................................................................................................................................................................................2 AUTACOIDS..........................................................................................................................................................................................................................................................2 BETABLOCKERS................................................................................................................................................................................................................................................2 BISPHOSPHONATES.........................................................................................................................................................................................................................................2 CATARACT NUGGETS.......................................................................................................................................................................................................................................3 CONDITION AND SPECIFIC DRUG...............................................................................................................................................................................................................4 CONDITION AND SPECIFIC SURGERY.......................................................................................................................................................................................................5 DIABETES NUGGETS ........................................................................................................................................................................................................................................6 DIFFERENT USAGE OF DRUGS.....................................................................................................................................................................................................................7 DRUG OF CHOICE...............................................................................................................................................................................................................................................7 DRUG KINETICS............................................................................................................................................................................................................................................... 11 FEW DRUG INTERACTIONS........................................................................................................................................................................................................................ 11 MECHANISM OF ACTION OF DRUGS....................................................................................................................................................................................................... 12 MONOCLONAL ANTIBODIES...................................................................................................................................................................................................................... 19 NITRATES NUGGET ....................................................................................................................................................................................................................................... 19 OPIOID NUGGET.............................................................................................................................................................................................................................................. 20 PRODRUGS ........................................................................................................................................................................................................................................................ 20 SAFEST DRUGS IN PREGNANCY NUGGET............................................................................................................................................................................................. 21 STEROID DRUGS ............................................................................................................................................................................................................................................. 21 TREATMENT OF CHOICE............................................................................................................................................................................................................................. 22
- 3. POINTS ABOUT DRUGS www.medpgnotes.com 2ANTICHOLINESTERASE ANTICHOLINESTERASE Naturallyoccurring Anticholinesterase Lipid Soluble Anticholinesterase Blood brain barrier crossing Anticholinesterase Physostigmine Anticholinesterase used in Myasthenia Gravis Neostigmine/Pyridostigmine Anticholinesterase used for Diagnosis of Mtasthenia Gravis Edrophonium Anticancer showing Anticholinesterase Property Irinotecan AUTACOIDS FUNCTION AUTAOIDS Most Important chemical elevating Hypothalamic setpoint PGE2 Vasoconstrictor PGF2 Prostaglandins causing Renal Vasodilataion PGI2,PGE2 Vasodilatation in blood vessels PGI2,PGE2,PGF2α Platelet Aggregation TXA2 Inhibition of Platelet aggregation PGI2 Chemotactic LTB4 Bronchoconstrictor Slow reacting substance of anaphylaxis(SRSA) LTC4 LTD4 LTE4 BETA BLOCKERS Most Cardioselective Vasodilator Property Nebivolol K+ Blocking Property Sotalol K+ Opening Property Tilsolol Selective β2 blocker Butoxamine Non Catecholamine acting selectively on β Prenalterenol BISPHOSPHONATES 1 st Bisphosphonate Approved Etindronate Treatment of Postmenopausal Osteoporosis Alendronate Risendronate Prevention of Steroid Induced Osteoporosis Risendronate Unique Administration Technique Once Yearly i.v/Once Monthly Oral Zolendronate Idandronate Most Potent Drug for Treatment & Prevention of Osteoporosis Bisphosphonates
- 4. POINTS ABOUT DRUGS www.medpgnotes.com 3CATARACTNUGGETS CATARACT NUGGETS Anterior Polar Perforation of corneal ulcer Anterior Capsular Vossious ring Anterior Subscapular Glaucoma Posterior Polar Mittendorf dot Posterior Capsular Posterior Subcapsular Steroid MC cause of blindness in India Cataract MC cause of blindness in Adults Cataract MC cause of blindness in children Keratomalacia MC cause of cataract Age Related MC Type of Congenital Cataract Punctate cataract MC Health Disorder among Geriatrics Visual Impairment/Cataract MC visually significant Congenital cataract Lamellar/Zonular cataract Lens changes in Anterior Uveitis Complicated Cataract with Posterior Capsular Opacities Second Sight Nuclear Cataract Fluctuation of Refractory Error Diabetic Cataract Complication of Intumescent Cataract Phacomorphic Glaucoma Complication of Morgagnian cataract Phacolytic Glaucoma Complication of Hypermature Sclerotic Cataract Subluxation/Dislocation of Lens Phacoanaphylactic Uveitis Cataract in Galactosemia is due to accumulation of Galactitiol Cataract in Diabetes due to accumulation of Sorbitol Galactosemia Oil Drop Cataract MC Ocular Complication of Systemic Steroid Cataract SPECIFIC CATARACT Snow Flake Cataract Diabetes Mellitus Sunflower Cataract Wilson’s disease Chalcosis Penetrating trauma Vossious ring on anterior surface of lens Rossette Shaped Cataract Blunt Trauma Christmas Tree cataract Myotonica Dystrophica Oil drop Cataract Galactosemia Morgagnian Cataract Hypermature Senile Cataract Rainbow cataract Breadcrumb Cataract Polychromatic Lusture Complicated Cataract Snow Blindness Ultraviolet Glass Blower’s Cataract Infrared