This document discusses glaucoma, which is characterized by optic nerve damage and elevated intraocular pressure caused by congestion of fluid in the eye. It can cause vision loss or blindness but is usually asymptomatic until late in the disease. Risk factors include age, family history, diabetes, and corticosteroid use. Treatment aims to prevent further optic nerve damage through medication, laser treatment, or surgery. The document also discusses cataracts, which are lens opacities that are the leading cause of blindness. Cataracts develop due to aging, trauma, radiation exposure, or systemic conditions. Early cataracts are treated with glasses but later cataracts require surgical removal and lens replacement.
glaucoma and cataract.pdf, After the class the students will be able :
Explain the structures and function of eye.
Explain the age affect on vision.
Describe the definition , etiology, risk factors, pathophysiology, medical management, surgical management and Nursing management of Glaucoma.
Describe the definition , etiology, risk factors, pathophysiology, medical management, surgical management and Nursing management of cataract.
List down the health education for Glaucoma and cataract.
cataract is clouding of the lens inside the eye..
it is very useful topic in medical filed...in this presentation all content is included about cataract like causes, symptoms and treatment...its very useful in your study.
complete information about the refractive errors due to the problem in the acomodation of eye lense , disturbed image formation in the retina, contains -types of disease condition .
This is a topic of sensory organ and this is detailed topic and can be refered by all nursing students bsc, msc and gnm which give you overall idea and things related to cataractwhich include definition, anat and physio, risk factor, pathophysiology, clinical menifestation, diagnostic evaluation, and management
Myopia classification and management by Tahir Shaukat Optometry Club
Nearsightedness (myopia) is a common vision condition in which you can see objects near to you clearly, but objects farther away are blurry. It occurs when the shape of your eye causes light rays to bend (refract) incorrectly, focusing images in front of your retina instead of on your retina.
glaucoma and cataract.pdf, After the class the students will be able :
Explain the structures and function of eye.
Explain the age affect on vision.
Describe the definition , etiology, risk factors, pathophysiology, medical management, surgical management and Nursing management of Glaucoma.
Describe the definition , etiology, risk factors, pathophysiology, medical management, surgical management and Nursing management of cataract.
List down the health education for Glaucoma and cataract.
cataract is clouding of the lens inside the eye..
it is very useful topic in medical filed...in this presentation all content is included about cataract like causes, symptoms and treatment...its very useful in your study.
complete information about the refractive errors due to the problem in the acomodation of eye lense , disturbed image formation in the retina, contains -types of disease condition .
This is a topic of sensory organ and this is detailed topic and can be refered by all nursing students bsc, msc and gnm which give you overall idea and things related to cataractwhich include definition, anat and physio, risk factor, pathophysiology, clinical menifestation, diagnostic evaluation, and management
Myopia classification and management by Tahir Shaukat Optometry Club
Nearsightedness (myopia) is a common vision condition in which you can see objects near to you clearly, but objects farther away are blurry. It occurs when the shape of your eye causes light rays to bend (refract) incorrectly, focusing images in front of your retina instead of on your retina.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
2. Refers to a group of ocular conditions
characterized by optic nerve damage.
A condition of elevated IOP .
The optic nerve damage is related to the IOP
caused by congestion of aqueous humor in the
eye.
3. Is the 2nd leading cause of blindness in adult
in the US.
Is more prevalent in people older than 40 yrs.
of age.
There is no cure for glaucoma, but this
disease can be control.
5. There are 2 theories regarding how increase
IOP damage the optic nerve in glaucoma.
The direct mechanical theory suggested :
High IOP damages the retinal layer as it
passes through the optic nerve head.
6. The indirect ischemic theory suggested that
high IOP compresses the microcirculation in
the optic nerve head, resulting in cell injury
and death.
7. Open angle glaucoma
Angle-closure glaucoma
Congenital glaucoma and
Glaucoma associated with other condition,
such as developmental anomalies or
corticosteroid use .
8. “Silent thief of sight”
Most pts. Are unaware that they have the
disease until they have experienced visual
changes and vision loss.
Blurred vision or “halos” around lights,
difficulty focusing , loss of peripheral vision,
aching or discomfort around the eye and
headache.
9. Ocular and medical history must be detailed to
investigate the history of predisposing
factors.
Tonometery to measure the IOP.
Ophthalmoscope to inspect the optic nerve.
Gonioscopy to examine the filtration angle of
the anterior chamber
Perimetry to assess the visual fields.
10. The aim of all glaucoma treat.
Is prevention of optic nerve damage.
Pharmacological therapy (miotics).
laser trabeculoplasty)
)
Laser procedures
surgery or a combination of these approaches
11. Is a lens opacity or cloudiness.
Cataract affecting 40 yrs old of age.
Cataract is the leading cause of blindness in
the world.
12. Pathophysiology :
Cataract can develop in one or both eyes at any
age.
Three common type of cataract are define by their
location in the lens:
1. Nuclear
2. Cortical
3. Posterior subcapsular
13. Visual impairment depends on their :
Size
Density
Location in the lens
More than one type can be present in the eye.
14. A nuclear cataract :tends to have a substantial
genetic component that causes a central
opacity in the lens. It is associated with
myopia.
A cortical cataract :involves the anterior,
posterior, or equatorial cortex of the lens.
Vision is worse in very bright light.
Posterior subcapsular cataract :occur in front
of the posterior or equatorial cortex of the
lens.
15. Aging
Loss of lens transparency
Decreased oxygen uptake
Decrease in level of vitamin C, protein
Increase in sodium and calcium
Accumulation of a yellow- brown pigment due
to the break-down of lens protein
23. Medications, eye drops, eye glasses
treatment cures cataract or prevents age-
related cataract.
In the early stage of cataract development,
glasses, contact lenses, may improve vision.
25. Providing preoperative care:
Withhold any anticoagulation(e.g. aspirin,
warfarin) to reduce the risk of hemorrhage.
Dilating drops are administer every 10 minutes
for 4 doses at least one hour before surgery.
26. Providing postoperative care:
The patient receive verbal and written
Instruction about how protect the
eye Administer medication
Recognizes the signs of complications and
obtain emergency care.
Instruct the patient to take a mild analgesia
agent, as needed.
Anti-inflammatory and corticosteroid eye
drops or ointment.
27. Teaching patient self care:
Eye patch for 24 hrs. after surgery.
followed by eye glasses worn during the
day,.
Sunglasses should be worn.
A clean , damp wash cloth may be used to
remove eye discharge.
28. Eye patch remove after the first follow up
appointment .
Vision is stabilized when the eye healed,
usually within 6-12 weeks.