Contents :
Anesthesiology instruments
General features of anesthetic instruments
Anesthetic cylinders
Pin index
Anesthetic gases
Anesthetic machines and circuits
Mapleson system
Oxygen control devices
Devices for co2 absorption
Dead space
Endotracheal tube
Laryngoscopy and endotracheal intubation
Nasotracheal intubation
Laryngeal mask airway
Trendelenberg position
General features of monitoring during anesthesia
Central venous pressure monitoring
Pulmonary artery catheter
Capnogram
Anesthetic complications
Air embolism
Respiratory complications
Malignant hyperthermia
Intraoperative and postoperative complications
Resuscitation
Mendelson syndrome
Hypothermia in anesthesia
Clinical anesthesia
History of anesthesia
Stages of anesthesia
Preanesthetic assessment
Pediatric anesthesia
Anesthesia in head injury
Cardiovascular anesthesia
Anesthesia in ent
Obstetric anesthesia
Anesthesia in orthopedics
Respiratory anesthesia
Day care anesthesia
Drugs of anesthesia
Preanesthetic drugs
General features of anesthetic drugs
Inhalational anesthetics
Minimum alveolar concentration
Partition coefficient
General features of inhalational anesthetics
Xenon
Nitrous oxide
Trilene
Ether
Helium
Chloroform
Halothane
Enflurane
Isoflurane
Desflurane
Sevoflurane
Methoxyflurane
Intravenous anesthetics
General features of intravenous anesthetics
Propofol
Ketamine
Thiopentone
Etomidate
Local anesthetics
General features of local anesthetics
Bupivacaine
Lignocaine
Prilocaine
Cocaine
Procaine
Bier’s block/IVRA
Peribulbar and retrobulbar block
Stellate ganglion block
Brachial plexus block
Celiac plexus block
Neuromuscular blockers
General features of neuromuscular blockers
Depolarising muscle relaxants – Succinly choline
Features of non depolarizing muscle blockers
D-tubocurarine
Pancuronium
Vecuronium
Mivacurium
Atracurium
Gallamine
Alcuronium
Spinal, epidural and caudal anesthesia and pain management
Splanchnic block
Neuraxial blockade
Spinal anesthesia
Epidural anesthesia
Caudal anesthesia
Other blocks
Pain
General features of pain
Assessment of pain
Analgesic drugs
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Contents :
Development of respiratory system
Anatomy of respiratory system
Physiology of respiratory system
General features of respiratory physiology
Inspiration and expiration
Surfactant
Gaseous exchange
Ventilation perfusion ratio and compliance
Hypercarbia and alveolar hypoventilation
Hyperventilation
High oxygen tension
Hypoxia
Features of hemoglobin
Oxyhemoglobin dissociation curve
Regulation of respiration
Lung volumes, capacities and alveolar ventilation
Acclimatisation
Mountain sickness
Caisson’s disease
Signs and symptoms of respiratory system
General signs and symptoms of respiratory system
Hemoptysis
Cyanosis
Clubbing
Pancoast tumor
Caplan syndrome
Pulmonary edema
ARDS
Pulmonary embolism
Pulmonary hypertension
Pulmonary venous hypertension
Cor pulmonale
Respiratory failure and pulmonary disease
Respiratory failure
Emphysema
Obstructive and restrictive lung disease
Respiratory curves
Bronchial asthma
Management of asthma
Chronic bronchitis
Bronchiectasis
Interstitial lung disease
Pneumoconiosis
Occupational lung disease
Asbestosis
Silicosis
Pulmonary hemosiderosis
Hypersensitive pneumonitis
Eosinophilia
Aspergillosis
Bronchiolitis
Laryngotracheobronchitis
Bronchial foreign body
Bronchoscopy
Solitary nodule
Pleural effusion, pneumothorax and mediastinitis
General features of pleura
Pleural effusion
Hemothorax
Pneumothorax
Lung sequestration
Mediastinum
Bronchopleural fistula
Pneumonia
General features of pneumonia
Causes of pneumonia
Morphology of pneumonia
Viral pneumonia
Staphylococcal pneumonia
Streptococcal pneumonia
Atypical pneumonia
Community acquired pneumonia
CMV pneumonia
Legionnaire’s pneumonia
Klebsiella pneumonia
Pneumocystis carnii pneumonia
Empyema
Lung abscess
Brochiolitis obliterans
Management of pneumonia
Tuberculosis
Mycobacterium tuberculosis
Epidemiology of tuberculosis
Features of tuberculosis
Morphology of tuberculosis
Tuberculin test
Sputum examination
Culture of mycobacterium
Diagnosis of tuberculosis
Treatment of tuberculosis
Sarcoidosis
Bronchogenic tumors
General features of brochogenic tumor
Small cell carcinoma of lung
Non small cell carcinoma of lungs
Management of bronchogenic tumor
Bronchial adenoma and bronchial cyst
Cystic fibrosis
Kartagener syndrome
Ventilator
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Experience with the implementation of the WHO checklist and briefing in the operating theatre. Krishna Moorthy. IV Internacional Conference on Patient Safety. (Madrid, Ministry of Health and Consumer Affairs, 2008)
Learn about the principles behind the surgical checklist and the evidence for adopting the checklist and how one NHS Board has applied the checklist to their surgical theatres and how another has expanded the checklist principle to other areas.
Learn about AORN's recommended practices for surgical attire in the perioperative setting. This presentation is from a webinar on August 8, 2012. Listen to the webinar for free to learn more, and you can also earn 1.0 contact hour: www.aorn.org/PreviouslyRecordedWebinars
Discover evidence-based practices to prevent sharps injuries and to reduce blood borne pathogen exposure to perioperative patients and personnel. This presentation is from a recent AORN webinar. Listen to the replay for free at http://bit.ly/1asAKXx. When registering for the replay, you can also earn one contact hour through June 27, 2014.
Contents :
Development of respiratory system
Anatomy of respiratory system
Physiology of respiratory system
General features of respiratory physiology
Inspiration and expiration
Surfactant
Gaseous exchange
Ventilation perfusion ratio and compliance
Hypercarbia and alveolar hypoventilation
Hyperventilation
High oxygen tension
Hypoxia
Features of hemoglobin
Oxyhemoglobin dissociation curve
Regulation of respiration
Lung volumes, capacities and alveolar ventilation
Acclimatisation
Mountain sickness
Caisson’s disease
Signs and symptoms of respiratory system
General signs and symptoms of respiratory system
Hemoptysis
Cyanosis
Clubbing
Pancoast tumor
Caplan syndrome
Pulmonary edema
ARDS
Pulmonary embolism
Pulmonary hypertension
Pulmonary venous hypertension
Cor pulmonale
Respiratory failure and pulmonary disease
Respiratory failure
Emphysema
Obstructive and restrictive lung disease
Respiratory curves
Bronchial asthma
Management of asthma
Chronic bronchitis
Bronchiectasis
Interstitial lung disease
Pneumoconiosis
Occupational lung disease
Asbestosis
Silicosis
Pulmonary hemosiderosis
Hypersensitive pneumonitis
Eosinophilia
Aspergillosis
Bronchiolitis
Laryngotracheobronchitis
Bronchial foreign body
Bronchoscopy
Solitary nodule
Pleural effusion, pneumothorax and mediastinitis
General features of pleura
Pleural effusion
Hemothorax
Pneumothorax
Lung sequestration
Mediastinum
Bronchopleural fistula
Pneumonia
General features of pneumonia
Causes of pneumonia
Morphology of pneumonia
Viral pneumonia
Staphylococcal pneumonia
Streptococcal pneumonia
Atypical pneumonia
Community acquired pneumonia
CMV pneumonia
Legionnaire’s pneumonia
Klebsiella pneumonia
Pneumocystis carnii pneumonia
Empyema
Lung abscess
Brochiolitis obliterans
Management of pneumonia
Tuberculosis
Mycobacterium tuberculosis
Epidemiology of tuberculosis
Features of tuberculosis
Morphology of tuberculosis
Tuberculin test
Sputum examination
Culture of mycobacterium
Diagnosis of tuberculosis
Treatment of tuberculosis
Sarcoidosis
Bronchogenic tumors
General features of brochogenic tumor
Small cell carcinoma of lung
Non small cell carcinoma of lungs
Management of bronchogenic tumor
Bronchial adenoma and bronchial cyst
Cystic fibrosis
Kartagener syndrome
Ventilator
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Experience with the implementation of the WHO checklist and briefing in the operating theatre. Krishna Moorthy. IV Internacional Conference on Patient Safety. (Madrid, Ministry of Health and Consumer Affairs, 2008)
Learn about the principles behind the surgical checklist and the evidence for adopting the checklist and how one NHS Board has applied the checklist to their surgical theatres and how another has expanded the checklist principle to other areas.
Learn about AORN's recommended practices for surgical attire in the perioperative setting. This presentation is from a webinar on August 8, 2012. Listen to the webinar for free to learn more, and you can also earn 1.0 contact hour: www.aorn.org/PreviouslyRecordedWebinars
Discover evidence-based practices to prevent sharps injuries and to reduce blood borne pathogen exposure to perioperative patients and personnel. This presentation is from a recent AORN webinar. Listen to the replay for free at http://bit.ly/1asAKXx. When registering for the replay, you can also earn one contact hour through June 27, 2014.
This presentation is from an AORN webinar that helps guide perioperative team members through the evidence appraisal and rating process using the AORN appraisal tools and evidence-rating model. The webinar replay is available for free at http://bit.ly/1i9r4En. Get the 2014 edition of Perioperative Standards and Recommended Practices at http://bit.ly/1bJmXAT.
Cleaning: It’s everyone’s responsibility. Review environmental cleaning procedures for all perioperative patient care areas (preoperative, OR, postoperative, and sterile processing). This information was originally shared in an AORN webinar, which is also available for free on demand at http://bit.ly/IHTNnp. One contact hour is available for the webinar through November 13, 2014. Learn more about AORN educational events at www.aorn.org/Events.
Discover what it takes to be a Perioperative Clinical Nurse Specialist. This presentation is from AORN's webinar which describes the role of the perioperative CNS, RN. Receive 0.5 contact hours by registering for the webinar replay and successfully completing the evaluation. The webinar is available at http://bit.ly/1aROqKI.
Interested in obtaining the new CNS-CP nursing credential? Learn valuable test-taking strategies and more through a CNS-CP Certification Exam Preparation Course: http://bit.ly/GQ5Yy0.
Purpose of the call:
•Review current data and state of the SSCL
•Discuss the role of communications and team work in patient safety
•Discuss and define how we can measure the effectiveness of the SSCL.
Read more and watch the webinar recording: http://bit.ly/1sXDqaZ
The correct application of the safety check steps in our routine theatre operations and procedures will greatly reduce surgically related mortality and morbidity.
Environmental cleaning depends on Infection Control risk Assessment as High, Moderate & Low Risk Areas. This document includes Procedures & Practices in Hospital for Environmental Cleaning & Disinfection based on cheapest hospital grade disinfectant i.e Clorox / Household Bleach available for especially third world countries.
Contents :
General forensic medicine
Identification
Primary teeth
Secondary teeth
Dentition
Estimation of age
Estimation of sex
Estimation of race
Estimation of stature
Death and postmortem
Death and changes after death
Autopsy
Postmortem temperature changes
Postmortem staining/postmortem lividity
Rigor mortis and cadaveric spasm
Mummification
Adipocere
Putrefaction
Maggots
Antemortem and postmortem burns
Asphyxia
Café coronary
Hanging
Different forms of asphyxia
Drowning
Firearm injuries
Types of firearm
Types of bullet
Types of firearm injuries
Wound and injury
Grievous injury
Injuries
Fractures
Wound
Law in relation to man
Courts
Evidence
Offence
IPC, CrPC and IEA
Inquest
Exhumation
Torture
Criminal responsibility
Consent
Medical law
Medical negligence
Tests and rules
Sexual offences
Rape
Other sexual offences
Infanticide and fetal death
Fetal death
Battered baby syndrome
Toxicology
General features of poisoning
Poisoning based on physiological state
Hydrogen sulphide
Arsenic
Lead
Phosphorus
Mercury
Copper
Zinc
Cadmium
Aluminium phosphide
Cyanide
Paracetamol poisoning
Salicylate poisoning
Copper sulphate poisoning
Acid poisoning
Sulphuric acid
Nitric acid
Carbolic acid
Oxalic acid
Kerosene poisoning
Carbon monoxide
Chloral hydrate
Methyl alcohol
Barbiturates
Aconite
Dhatura
Strychnine
Opc
Preservatives for poisoning
Snakes
Mushroom poisoning
Plant poison
General features of management of poisoning
Hemodialysis
Alkaline diuresis
Saline diuresis
Gastric lavage
BAL
EDTA
Metallothienes
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
This presentation is from an AORN webinar that helps guide perioperative team members through the evidence appraisal and rating process using the AORN appraisal tools and evidence-rating model. The webinar replay is available for free at http://bit.ly/1i9r4En. Get the 2014 edition of Perioperative Standards and Recommended Practices at http://bit.ly/1bJmXAT.
Cleaning: It’s everyone’s responsibility. Review environmental cleaning procedures for all perioperative patient care areas (preoperative, OR, postoperative, and sterile processing). This information was originally shared in an AORN webinar, which is also available for free on demand at http://bit.ly/IHTNnp. One contact hour is available for the webinar through November 13, 2014. Learn more about AORN educational events at www.aorn.org/Events.
Discover what it takes to be a Perioperative Clinical Nurse Specialist. This presentation is from AORN's webinar which describes the role of the perioperative CNS, RN. Receive 0.5 contact hours by registering for the webinar replay and successfully completing the evaluation. The webinar is available at http://bit.ly/1aROqKI.
Interested in obtaining the new CNS-CP nursing credential? Learn valuable test-taking strategies and more through a CNS-CP Certification Exam Preparation Course: http://bit.ly/GQ5Yy0.
Purpose of the call:
•Review current data and state of the SSCL
•Discuss the role of communications and team work in patient safety
•Discuss and define how we can measure the effectiveness of the SSCL.
Read more and watch the webinar recording: http://bit.ly/1sXDqaZ
The correct application of the safety check steps in our routine theatre operations and procedures will greatly reduce surgically related mortality and morbidity.
Environmental cleaning depends on Infection Control risk Assessment as High, Moderate & Low Risk Areas. This document includes Procedures & Practices in Hospital for Environmental Cleaning & Disinfection based on cheapest hospital grade disinfectant i.e Clorox / Household Bleach available for especially third world countries.
Contents :
General forensic medicine
Identification
Primary teeth
Secondary teeth
Dentition
Estimation of age
Estimation of sex
Estimation of race
Estimation of stature
Death and postmortem
Death and changes after death
Autopsy
Postmortem temperature changes
Postmortem staining/postmortem lividity
Rigor mortis and cadaveric spasm
Mummification
Adipocere
Putrefaction
Maggots
Antemortem and postmortem burns
Asphyxia
Café coronary
Hanging
Different forms of asphyxia
Drowning
Firearm injuries
Types of firearm
Types of bullet
Types of firearm injuries
Wound and injury
Grievous injury
Injuries
Fractures
Wound
Law in relation to man
Courts
Evidence
Offence
IPC, CrPC and IEA
Inquest
Exhumation
Torture
Criminal responsibility
Consent
Medical law
Medical negligence
Tests and rules
Sexual offences
Rape
Other sexual offences
Infanticide and fetal death
Fetal death
Battered baby syndrome
Toxicology
General features of poisoning
Poisoning based on physiological state
Hydrogen sulphide
Arsenic
Lead
Phosphorus
Mercury
Copper
Zinc
Cadmium
Aluminium phosphide
Cyanide
Paracetamol poisoning
Salicylate poisoning
Copper sulphate poisoning
Acid poisoning
Sulphuric acid
Nitric acid
Carbolic acid
Oxalic acid
Kerosene poisoning
Carbon monoxide
Chloral hydrate
Methyl alcohol
Barbiturates
Aconite
Dhatura
Strychnine
Opc
Preservatives for poisoning
Snakes
Mushroom poisoning
Plant poison
General features of management of poisoning
Hemodialysis
Alkaline diuresis
Saline diuresis
Gastric lavage
BAL
EDTA
Metallothienes
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Application of nanotechnologies: Medicine and healthcareNANOYOU
An introduction to the applications of nanotechnologies in medicine.
This chapter is part of the NANOYOU training kit for teachers.
For more resources on nanotechnologies visit: www.nanoyou.eu
Geology and Stratigraphy of Hazara,Mansehra and Oghi Khaki Road PakistanHammad Ahmad Sheikh
A detail field report on Stratigraphy of the the Hazara Basin,Mansehra and Oghi Khaki Road.
Beside this there is a detailed description on the Drilling Rig and working and One day visit to Tarbela Dam.
Contents :
General features of nutrition
Assessment of nutritional status
Features of assessment of nutritional status
Short stature
Malnutrition
General features of malnutrition
Acute and chronic malnutrition
Kwarshiorkar
Marasmus
Management of malnutrition
Vitamins
General features of vitamins
General features of vitamin A
Features of vitamin A deficiency
Prophylaxis and treatment of vitamin A deficiency
Hypervitaminosis A
Vitamin D
Vitamin E
Vitamin K
General features of vitamin B
Thiamine
Riboflavin
Niacin
Vitamin B6
Vitamin B12
Pantothenic acid
Biotin
Vitamin C
Folic acid
Scurvy
Minerals
General features of minerals
Iron
Zinc
Fluoride
Iodine
Calcium
Copper
Chromium
Selenium
Milk and egg
Milk and pasteurisation
Egg
Breast feeding
General features of breast feeding
Breast milk
Colostrum
Storage of breast milk
Proteins and amino acids
General features of proteins
Protein indicators
Fatty acids
Food fortification
Toxins in food
Food adulteration
Diet
Dietary cycle and nutritional surveillance
Calorie requirements
Calorie requirements of adult
Supplementary nutrition in icds
RDA
Prudent diet
Indian reference male and female
Food standards
Dietary fibre
Probiotic and prebiotic
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Contents :
Ear
Development of ear
Anatomy of ear
Physiology of ear
Tests for hearing
Hearing loss
Ototoxicity
Management of hearing loss
Assessment of cochlear and vestibular function
Diseases of external ear
Features of middle ear diseases
Management of middle ear diseases
Meniere’s disease
Otosclerosis
Facial nerve
Bell’s palsy
Ramsay hunt syndrome
Cerebellopontine angle tumors
Glomus tumor
Pierre robbin syndrome
Nose
General features of nose
Anatomy of nose
Physiology of nose
Choanal atresia
Rhinolalia
CSF rhinorrhoea
Deviated nasal septum
Granulomatous diseases of nose
Allergic rhinitis
Atrophic rhinitis
Hypertrophic rhinitis
Epistaxis
Juvenile nasopharyngeal angiofibroma
Nasopharyngeal carcinoma
Nasal polyposis
Foreign body in nose
Paranasal sinuses
Development of paranasal sinuses
Anatomy of paranasal sinuses
Physiology of paranasal sinuses
Sinusitis
Management of sinusitis
Sinonasal tumors
Pharynx
Development of pharynx
Anatomy of pharynx
Zenker’s diverticulum
Plummer vinson syndrome
Head and neck space inflammation
Adenoid hypertrophy
Anatomy of tonsils
Tonsillitis and quinsy
Management of tonsillitis
Oral cavity
General features of oral cavity
Ranula
Vincent’s angina
Ludwing’s angina
Oral lesions, oral cyst, sinus and fistula
Maxillofacial injuries
Anatomy of salivary glands
Diseases of salivary glands
Management of salivary gland diseases
Anatomy of tongue
Malignancy of tongue
Anatomy of palate
Malignancy of palate
Carcinoma lip
Carcinoma cheek
Features of carcinoma oral cavity
Management of carcinoma oral cavity
Larynx
Development of larynx
Anatomy of larynx
Physiology of larynx
Stridor
Laryngocele
Laryngomalacia
Vocal nodule
Laryngoscopy
Epiglottitis
Laryngitis
Vocal cord paralysis
Diseases of speech
Diseases of larynx
Tumors of larynx
Features of carcinoma larynx
Diagnosis of carcinoma larynx
Management of carcinoma larynx
Tracheostomy
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Contents :
Introduction to pharmacology
General features of pharmacology
Clinical trials
Metabolism of drugs
Kinetics
Enzyme inducers and inhibitors
Drug distribution and clearance
Route of administration
Therapeutic index
Prodrug
Bioavailability and first pass metabolism
Agonist, antagonist and inverse agonist
Excretion of drug
Drug binding
Transport of drug
Pharmacogenetics
Drug and food
Immunomodulators
General features of immunomodulators
Cyclosporine and tacrolimus
Levamizole
Mycophenolate mofetil
Imiqumod
Thalidomide
Anti TNF alpha drugs
Monoclonal antibodies
Autacoids
General features of autacoids
NSAIDs
Prostaglandins
Leukotrienes
Thromboxane
Antihistaminic drugs
Drugs acting on 5ht
Colchicine
Adverse reactions
Antibiotic therapy
General features of antibiotic therapy
Betalactams
Penicillin
Cephalosporins
Aminoglycosides
Linezolid
Macrolide antibiotics
Glycopeptides antibiotics
Chloramphenicol
Sulfonamides
Tetracycline derivatives
Quinolones
Antifungal drugs
Antiviral drugs
Antiprotozoal drugs
Anti helminthic drugs
Anticancer drugs
General features of anticancer drugs
Methotrexate
Cyclophosphamide and ifosfamide
5-fluorouracil
Bleomycin
Vincristine and vinblastine
Paclitaxel
Actinomycin D
6-Mercaptopurine
Doxorubicin
Cisplatin
Autonomous nervous system
General features of autonomic nervous system
Cholinergic drugs
Anticholinergic drugs
Adrenergic drugs
Adrenergic blocking agents
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Contents :
Systemic lupus erythematosus
General features of SLE
Hematological manifestations of SLE
Cardiovascular manifestations of SLE
Respiratory system involvement in SLE
Renal involvement in SLE
Dermatological manifestations of SLE
Gastrointestinal features of SLE
Drug induced lupus
Joint involvement in SLE
Diagnosis of SLE
Management of SLE
Rheumatoid arthritis
General features of rheumatoid arthritis
Juvenile rheumatoid arthritis
Extra articular manifestations of rheumatoid arthritis
Diagnosis of rheumatoid arthritis
Management of rheumatoid arthritis
Scleroderma and systemic sclerosis
Scleroderma
Systemic sclerosis
Sjogren’s syndrome
Marfan’s syndrome
Ehler danlos syndrome
Osteoarthritis
Features of osteoarthritis
Diagnosis of osteoarthritis
Management of osteoarthritis
Gout and pseudogout
Features of gout
Diagnosis of gout
Management of gout
Pseudogout
Raynaud phenomenon
Amyloidosis
Features of amyloidosis
Diagnosis of amyloidosis
Seronegative arthritis
Features of seronegative arthritis
Ankylosing spondylitis
Reiter’s syndrome
Relapsing polychondritis
Neuropathic joint
Causes of neuropathic joint
Features of neuropathic joint
Vasculitis
General features of vasculitis
Wegener’s granulomatosis
Polyarteritis nodosa
Microscopic polyangitis
Churg strauss syndrome
Temporal arteritis
Kawasaki disease
Takayasu arteritis
Fibromuscular dysplasia
Cryoglobulinemia
Henoch schonlein purpura
Bechcet’ s syndrome
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Contents :
General biochemistry
General features of biochemistry
Studies
Bonds
pH and buffers
Energy
Pathyways in cytosol and mitochondria
Carbohydrates
Epimers and enantiomers
Structure of carbohydrates
Glucose transporters
Cori cycle
Glucose
Glycolysis
Acetyl coA
Kreb’s cycle
Gluconeogenesis
Glycogenolysis
Electron transport chain
HMP shunt
Glucose phosphate dehydrogenase deficiency
Fructose metabolism
Lactose metabolism
General features of glycogen storage disorders
Von gierke’s disease
Disorders of galactose metabolism
Substrate level phosphorylation
Lipids
Fatty acids
Synthesis of fatty acids
Oxidation of fatty acids
General features of lipoprotein
Lipoprotein lipase
Chylomicron
LDL
VLDL
HDL
Apoprotein
Cholesterol
Hypercholesterolemia
Xanthoma
Abetalipoproteinemia
Bile acids
Ketone bodies
Starvation
Aminoacids
General features of aminoacids
Proline
Valine
Leucine
Arginine
Histidine
Glycine
Alanine
Phenylalanine
Tyrosine
Tryptophan
Cysteine
Methionine
Homocysteine
Aspartate
Glutamate
Glutamine
Lysine
Glutathione
Creatinine
General features of disorders of aminoacid metabolism
Phenylketonuria
Maple syrup urine disease
Multiple carboxylase deficiency
Hartnup disease
Alkaptonuria
Ammonia
Urea
Glutamate dehydrogenase
Disorders of heme synthesis
Porphyrin and porphyria
Proteins and enzymes
Structure of protein
Determination of protein structure
Glycoproteins
Proteoglycan
Types of protein
Estimation of proteins
Denaturation of proteins
Separation of proteins
General features of enzymes
Oxidase
Oxygenase
Dehydrogenase
Hydrolase
Transferase
Ligase
Lyase
Holoenzyme
Transamination
Serine protease
Enzyme inhibition
Enzyme regulation
Ribozymes
Isoenzymes
Components of enzymes
Coenzymes and cofactors for enzymes
Informational macromolecules
Purine metabolism
Pyrimidine metabolism
Structure of DNA
Histone
Mitochondrial DNA
Telomerase
Replication of DNA
Genetic code
Introns and exons
Mutation
Regulation of DNA
General features of transcription
RNA polymerase
Post transcriptional modification
Splicing
rRNA
mRNA
tRNA
microRNA
Ribosomes
Translation
Post translational modification
Protein folding
Inborn errors of metabolism
General features of inborn errors of metabolism
Tay sach’s disease
Gaucher’s disease
Niemann pick disease
For more details, visit www.medpgnotes.com
You can send your queries to medpgnotes@gmail.com
Acute heart failure: diagnosing and managing acute heart failure in adultsEmergency Live
The need for this guideline was identified as the NICE guidelines on chronic heart failure were being updated. We recognised at this time that there were important aspects of the diagnosis and management of acute heart failure that were not being addressed by the chronic heart failure guideline, which focussed on long term management rather than the immediate care of someone who is acutely unwell as a result of heart failure. The aim of this guideline is to provide guidance to the NHS on the diagnosis and management of acute heart failure.
Heart failure is a condition in which the heart does not pump enough blood to meet all the needs of the body. It is caused by heart muscle damage or dysfunction, valve problems, heart rhythm disturbances and other rarer causes. Acute heart failure can present as new-onset heart failure in people without known cardiac dysfunction, or as acute decompensation of chronic heart failure.
Acute heart failure is a common cause of admission to hospital (over 67,000 admissions in England and Wales per year) and is the leading cause of hospital admission in people 65 years or older in the UK.
This guideline includes important aspects of the diagnosis and management of acute heart failure that are not addressed by the NICE guideline on chronic heart failure (NICE clinical guideline 108). The guideline on chronic heart failure focused on long-term management rather than the immediate care of someone who is acutely unwell as a result of heart failure.
This guideline covers the care of adults (aged 18 years or older) who have a diagnosis of acute heart failure, have possible acute heart failure, or are being investigated for acute heart failure. It includes the following key clinical areas.
Contents :
Amyloid
Apoprotein
Arthritis
Avascular necrosis
Bone graft
Brain
Bronchogenic carcinoma
Census
Clotting factors
Contraception
Inflammatory bowel disease
Cerebrospinal fluid
Culture media
Dementia
Electroencephalogram
Engaging diameter
Estrogen
Familial hyperlipoproteinemia
Features of fibroid
Firearm
Gastric motility
Absorption in gut and nephron
Hormones
Hypersensitivity
Immunoglobulin
Inborn errors of metabolism and deficient enzymes
Kidney stones
Lithium
Lung volumes and capacities
Metabolic acidosis
Mosquito
Nerve fibers
Muscles and nerve supply
Changes in pregnancy
Methods for proteins
Protooncogenes and tumor suppressor genes
Radioisotopes
Rickettsial zoonoses
Root values for reflexes
Rapidly progressing glomerulonephritis
Small intestinal biopsy
Specimen preservation in poisoning
Sexually transmitted diseases
Sterilization and disinfection
Tetanus
Toxins in food
Management of poisoning
Vaccination
Vaginal cytology
Vitamins
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Contents :
Anticholinesterase
Autacoids
Beta blockers
Bisphosphonates
Cataract nuggets
Condition and specific drug
Condition and specific surgery
Diabetes nuggets
Different usage of drugs
Drug of choice
Drug kinetics
Few drug interactions
Mechanism of action of drugs
Monoclonal antibodies
Nitrates nugget
Opioid nugget
Prodrugs
Safest drugs in pregnancy nugget
Steroid drugs
Treatment of choice
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Contents :
Most commons
Most common type
Most common cause
Most common form
Most common lesion
Most common complication
Most common Joint
Most common indication
Most common manifestation
Most common mode
Most common nerve
Most common side effect
Most common presentation
Most common site
Most common tumor
Contents :
Age group for diseases
Dentition
Developmental milestones
Gestational weeks
Important days
Important duration
Important years
Infectious diseases and incubation period
Paranasal sinuses
Period of communicability
Primitive reflexes
Psychosexual stages of development
Other important timelines
Best time for surgery
Trimesters
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Contents :
Sensitive and specific antibodies
Specific calcification
Cast / brace/ splint
Enzymes of mitochondria and cytosol
Human leucocyte antigen
Inhibitors in biochemistry
Types of joints
Longest and shortest acting drugs
Male and female analogue
Male and female preponderance
Mode of inheritance
Named fractures
Important tables in nutrition chapter
Specific names in orthopedics
Rate limiting enzymes
Physiology of receptors
Right and left laterality
Sensitive and resistive to radiation
Sensitive and specific investigation
Condition and specific terms
Names of staging/grading/prognostic system
Surgery names
Tumor marker
Vectors
X ray views
Important lists
Important tables in anesthesiology
Important tables in dermatology
Important tables in embryology
Clarke’s grouping of heart diseases in pregnancy
Forrest classification
Classification of leprosy
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Contents :
Artery
Brain Lobes
Cause Of Death
Gene
Length
Mineral
Nerve
Organ
Organisms
Heart Valves
Vein
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Contents :
Amino acid
Best time
Bursa and spaces
Classification of steroid hormones
Country, state and cities
Curve
Interleukins
Dermatome
Disease
Drugs
Source of energy
Enzymes
Finding
Gas
Host
Infectious disease
Instrument
Investigation
Ion
Ligament
Lobes and fissures of liver
Micromolecule
Muscle
Neoplasm
Neurotransmitter
Numericals
Organelle
Part of body
Female pelvis
Reflex
Relations
Sample
Secretions
Stomach
Stratum
Surgical procedures
Symptom
Treatment
All except
Catchy points
Because
Fact
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Contents :
Angles
ATP’s produced
Body fluids
Areas of brain
Chromosomal translocations
Cloning capacities
Criminal procedure codes and Indian Evidence Act
Decibel values
Important dosages
Fatal dose of poisons
Fetal diameters
Flow cytometry markers
Important normal values
IPC
Subject wise numerical values
One gram equivalent
Pediatric normal values
Pelvic diameters
Important percentages
Specific gravity and pH
Pin index
Population norms
Pressures
Duration for diagnosis in psychiatry
Refractory index
Temperature
Volume
Wavelength
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Contents
Chromosomes
Circles
Named diseases
Laws
Maneuver
Location of receptors
Signs
Syndromes
Tests
Triads and pentads
Triangles
Vertebral levels
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Contents :
Adverse effects of drugs
Anatomical landmarks and contents
Bodies
Named cells
Named deformities
Dyes
Epithelium
Named fascia
Formula
Named lines
Lymphatic drainage
Markers
Odour
Ossification
Radiological signs
Scientists
Stains
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Contents :
Radiodiagnosis
General features of radiodiagnostic techniques
X ray
X-ray features of heart
X-ray features of lung
Computed tomography
Magnetic resonance imaging
Ultrasonography
Myelography
PET scan
Contrast agents
Radiotherapy
Physics of radiotherapy
Rays
Radioisotopes
Units in radiotherapy
Radiosensitive and radioresistant
Types of radiotherapy
Brachytherapy
Effects of radiation
Radiosensitizers and radioprotectors
Radiation doses
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Contents :
Signs and symptoms in psychiatry
General features of psychiatric symptoms
Delusion
Illusion
Hallucination
Tests in psychiatry
Substance related disorders
General features of substance related disorders
Amphetamine
Cocaine
Cannabis
LSD
Alcohol
Delirium tremens
Fetal alcohol syndrome
Opioid receptors
Opioid drugs
Opioid poisoning
Treatment of opioid poisoning
Nicotine
Caffeine
Cognitive disorders
Features of cognitive disorders
Organic brain syndrome
Delirium
Amnestic disorders
Dementia
Alzheimer’s disease
Schizophrenia
Risk of schizophrenia
Features of schizophrenia
Types of schizophrenia
Management of schizophrenia
Mood disorders
Depression
Mania
Bipolar disorders
Suicide
Management of mood disorders
Lithium
Anxiety disorders
General features of anxiety disorders
Generalised anxiety disorders
Anxiety neurosis
Post traumatic stress disorder
Panic attack and panic disorders
Phobia
Obsessive compulsive disorder
Adjustment disorder
Pre menstrual tension
Psychoanalysis, ego and ego defence mechanisms
Psychoanalysis
Id, ego and superego
Ego defence mechanisms
Researchers in psychiatry
Learning and management techniques in psychiatry
Psychosexual stages of development
Personality disorders
Somatoform disorder
Somatisation disorder
Fibromyalgia
Hysteria
Hypochondriasis
Dissociative disorders
Gender identity and sexual disorders
Gender identity disorders
Impotence
Erectile dysfunction
Premature ejaculation
Eating disorders
Sleep disorders
General features of sleep disorders
EEG
REM sleep
NREM sleep
Narcolepsy
Impulsive disorders
Pediatric psychiatry
General features of pediatric psychiatry
Attention deficit hyperactive disorder
Autism
Mental retardation
Conduct disorder and specific learning disorder
Manchausen syndrome
Treatment in psychiatry
Antipsychotics
Neuroleptic malignant syndrome
Antidepressant drugs
MAO inhibitors
Seratonin syndrome
Antianxiety drugs
Benzodiazepine antagonist
Drugs acting on GABA
Electroconvulsive therapy
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Contents :
Embryology of male reproductive system
Anatomy of male reproductive system
Physiology of male reproductive system
Testicular tumors
General features of testicular tumor
Choriocarcinoma
Seminoma
Dermoid
Cryptorchidism
Ectopic testis
Varicocele
Spermatocele
Hydrocele
Torsion of testis
Infections of male reproductive system
Prostate
Anatomy of prostate
General features of prostate
Prostatitis
General features of benign prostatic hyperplasia
Management of benign prostatic hyperplasia
Features of prostatic carcinoma
Management of prostatic carcinoma
Transurethral resection of prostate
Penis
General features of penis
Lesions of penis
Malignancy of penis
Drugs of male reproductive system
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Contents :
Transplantation
Types of graft
Graft rejection
Runt disease
Organ transplantation
Immune system
Types of immunity
General features of immune system
Superantigen
Major histocompatibility complex
Natural killer cells
Antigen presenting cells
T cells, b cells and plasma cells
Lymphoid organs
Diseases of immune system
Bruton’s agammaglobulinemia
Severe combined immunodeficiency
Job’s syndrome
Hyper IgM syndrome
Autoimmune diseases
Di George syndrome
Antibodies associated with diseases
Antigen and antibody
Antigen
Antibody
Antigen antibody interaction
Tests for antigen and antibody
Immunoglobulins
Structure of immunoglobulin
Physiology of immunoglobulin
General features of immunoglobulin
Ig G
Ig A
Ig M
Ig D
Ig E
Hypersensitivity
General features of hypersensitivity reactions
Type I hypersensitivity
Type II hypersensitivity
Type III hypersensitivity
Type IV hypersensitivity
Immunohistochemistry markers
Vaccination
General features of vaccination
Live and killed vaccines
Universal immunization programme
National immunisation programme
Expanded programme for immunisation
Adjuvant
Herd immunity
Storage of vaccines
Measles vaccine
Rubella vaccine
Cholera vaccine
Typhoid vaccine
Yellow fever vaccine
Pneumococcal vaccine
Oral polio vaccine
Reverse cold chain
Injectable polio vaccine
DPT vaccine
BCG vaccine
MMR vaccine
Rabies vaccine
Influenza vaccine
Hepatitis A vaccine
Hepatitis B vaccine
Hemophilus influenza b vaccine
Chicken pox vaccine
Meningococcal vaccine
Japanese encephalitis vaccine
Rotavirus vaccine
HPV vaccine
Vaccination of unimmunised child
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Contents :
Red blood cells
General features of red blood cells
Red cell indicators
Erythropoietin
Hematopoiesis
Peripheral blood smear
Hemoglobin
General features of red blood cell disorders
Hypochromic microcytic anemia
Iron deficiency anemia
Megaloblastic anemia
Pernicious anemia
Anemia of chronic disease
Sideroblastic anemia
Features of hemolytic anemia
Hereditary spherocytosis
G6PD deficiency
Sickle cell anemia
Thalassemia
Autoimmune hemolytic anemia
Microangiopathic hemolytic anemia
Paroxysmal nocturnal hemoglobinuria
Paroxysmal cold hemoglobinuria
Aplastic anemia
Pancytopenia and fanconi anemia
Myelodysplastic syndrome
Myeloproliferative disorders
Polycythemia
Myelofibrosis
Essential thrombocytosis
White blood cells
General features of white blood cells
Neutrophils
Eosinophils
Monocyte
Lymphocytes
Leukocyte adhesion deficiency
General features of leukemia
Acute lymphoblastic leukemia
Acute myeloblastic leukemia
Chronic lymphocytic leukemia
Chronic myelocytic leukemia
General features of lymphoma
Hodgkin’s lymphoma
Non Hodgkin’s lymphoma
Burkitt’s lymphoma
Hairy cell leukemia
Mantle cell lymphoma
Follicular lymphoma
Post transplant lymphoma
Bleeding and coagulation disorders
General features of bleeding and coagulation disorders
General features of platelets and endothelial cells
Pathways of coagulation
Clotting factors
Thrombomodulin
Hemophilia
Von willebrand disease
Glanzmann thrombaesthenia
Bernard soulier syndrome
Wiskott aldrich syndrome
Thrombocytopenia and purpura
Idiopathic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura
Disseminated intravascular coagulation
Antiphospholipid antibody syndrome
General features of hypercoagulable disorders
Budd chiari syndrome
Hemolytic uremic syndrome
Plasma cell disorders
General features of myeloma
Features of multiple myeloma
Management of multiple myeloma
Drugs acting on blood
General features of drugs acting on blood
Heparin
Warfarin
Antiplatelet drugs
Thrombolytics
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Contents :
General features of genes and chromosomes
General features of genetics
General features of chromosomes
Barr body
Genes
Aneuploidy
Chromosomes
Cytogenetics and DNA recombinant technology
General features of cytogenetic studies
Polymerase chain reaction
Restriction fragment length polymorphism
DNA fingerprinting
Fluorescence and luminence
Karyotyping
Blotting
Hybridoma technology
Genetic studies
Chromosomal studies
Transgenic animals
Gene incorporation
Recombinant technology
Gene therapy
Mode of inheritance of diseases
Inheritance of diseases
Features of inheritance
Mitochondrial inheritance
Genetic disorders
General features of genetic disorders
Rearrangement of transcription factors
Down’s syndrome
Trisomy 13
Trisomy 18
Trisomy 22
Turner syndrome
Klinefelter syndrome
Noonan syndrome
Disorders of DNA repair mechanism
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Contents :
Growth and development
Head circumference
Weight
Height
Fontanelle
Growth
Growth chart
Adolescence
Childhood disorders
Developmental milestones
General features of developmental milestones
Speech
Cubes
Gross motor
Fine motor
Social milestones
Neonatology
General features of neonatology
Kangaroo mother care
Feeding of neonates
Normal findings in neonates
Abnormal findings in neonates
General features of neonatal diseases
Neonatal resuscitation
Neonatal diarrhoea
Neonatal sepsis
Surfactant
Features of respiratory distress syndrome
Investigation of respiratory distress syndrome
Silverman anderson scoring
Treatment of respiratory distress syndrome
Meconium aspiration syndrome
Necrotizing enterocolitis
Neonatal seizures
Transient tachypnea of newborn
Neonatal jaundice
Infant born to diabetic mother
Neonatal asphyxia
Cerebral palsy
Breath holding spells
Primitive reflexes
APGAR score
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Contents :
General features of pathology
Features of cell injury
Hypoxia
Ageing
Necrosis
General features of apoptosis
Apoptotic and anti apoptotic protein
Calcification
Atrophy and hypertrophy
Hyperplasia and metaplasia
Stem cells
Fixatives and stains
Pigment
Bactericidal system
Hydrogen peroxidase
Oxidative stress
Free radical
NADPH oxidase
Basement membrane
Inflammation
Inflammatory mediators
Hydrostatic and osmotic pressure
General features of inflammation
Systemic inflammatory response syndrome
Autoantigen and associated diseases
Acute inflammation
Chronic inflammation
Chronic granulomatous disease
Granuloma
Complement system
Opsonization
Phagocytosis
Chediak higashi syndrome
Chemotaxis
Neoplasia
Cell cycle
Causes of neoplasia
Features of neoplasia
Protooncogenes and tumor suppressor genes
Management of neoplasia
General features of tumor markers
CA-125
CEA
AFP
Features of tumors
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Contents :
Blood transfusion
Blood grouping
Blood components
Blood transfusion
Complications of blood transfusion
Electrolyte abnormalities
Anion gap
General features of acid base disorders
Interpretation of abg values
Metabolic acidosis
Metabolic alkalosis
Respiratory acidosis
Respiratory alkalosis
Enteral nutrition
Total parenteral nutrition
Features of TPN
Complications of TPN
Shock
General features of shock
Anaphylactic shock
Hypovolemic shock
Septic shock
Cardiogenic shock
Neurogenic shock
Hemorrhagic shock
Management of shock
Electrolyte imbalance
General features of electrolyte imbalance
Intravenous fluids
Water
Sodium
Hypernatremia
Hyponatremia
Potassium
Hyperkalemia
Hypokalemia
Magnesium
Hypermagnesemia
Hypomagnesemia
Phosphate
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Contents :
Development of excretory system
Anatomy of excretory system
General features of anatomy of excretory system
Anatomy of kidney
Anatomy of ureter
Physiology of excretory system
General features of physiology of excretory system
Renin angiotensin system
Physiology of micturition
Glomerular function
Tubular function
Counter current mechanism
Concentration of urine
Congenital diseases of kidney
General features of congenital diseases of kidney
Polycystic kidney disease
Cystic diseases of kidney
Nephronophthisis
Posterior urethral valve
Vesicoureteric reflux
Ureterocele
Hydronephrosis
Hypospadiasis
Epispadiasis
Phimosis and paraphimosis
Peyronie’s disease
Priapism
Acute retention of urine
Glomerular diseases
General features of glomerular diseases
Minimal change disease
Nephrotic syndrome
Post streptococcal glomerulonephritis
Membranous glomerulonephritis
Membranoproliferative glomerulonephritis
Mesangioproliferative glomerulonephritis
Focal segmental glomerulonephritis
Focal segmental glomerulosclerosis
Collapsing glomerulopathy
IgA neprhopathy
Rapidly progressing glomerulonephritis
Alport syndrome
Goodpasture syndrome
Diabetic nephropathy
Chronic glomerulonephritis
Renal tubular acidosis
Kidney stones
General features of renal stones
Types of renal stones
Diagnosis of renal stones
Management of renal stones
Nephrocalcinosis
Renal tuberculosis
General features of renal tuberculosis
Diagnosis of renal tuberculosis
Management of renal tuberculosis
Renal trauma
Renal tumors
Features of renal tumors
Renal cell carcinoma
Wilm’s tumor
Renal failure
General features of renal failure
Acute renal failure
Acute tubular necrosis
Prerenal azotemia
Chronic renal failure
Intersitial nephritis
Papillary necrosis
Acute pyelonephritis
Chronic pyelonephritis
Emphysematous pyelonephritis
Xanthogranulomatous kidney
Chinese herb and balkan nephropathy
Hemodialysis
Renal transplantation
Renal vascular disorders
Renal artery disorder
Renal vein disorder
Renal imaging
Urinary bladder
General features of bladder
Urinary bladder cancer
Bladder injuries
Urethra
General features of urethra
Urethral injuries
Urethral stricture
Urinalysis
Drugs acting on kidney
General features of drugs acting on kidney
Loop diuretic
Thiazide diuretic
Aldosterone antagonist
Carbonic anhydrase inhibitors
Osmotic diuretics
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Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar Kanvaria
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
2. ANESTHESIOLOGY
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1ANESTHESIOLOGY INSTRUMENTS
CONTENTS
ANESTHESIOLOGY INSTRUMENTS................................................................................................................................. 4
GENERAL FEATURES OF ANESTHETIC INSTRUMENTS ............................................................................................... 4
ANESTHETIC CYLINDERS............................................................................................................................................ 4
PIN INDEX.................................................................................................................................................................. 4
ANESTHETIC GASES................................................................................................................................................... 4
ANESTHETIC MACHINES AND CIRCUITS.................................................................................................................... 5
MAPLESON SYSTEM .................................................................................................................................................. 5
OXYGEN CONTROL DEVICES...................................................................................................................................... 5
DEVICES FOR CO2 ABSORPTION ............................................................................................................................... 6
DEAD SPACE.............................................................................................................................................................. 6
ENDOTRACHEAL TUBE .............................................................................................................................................. 7
LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION............................................................................................... 7
NASOTRACHEAL INTUBATION................................................................................................................................... 9
LARYNGEAL MASK AIRWAY....................................................................................................................................... 9
TRENDELENBERG POSITION...................................................................................................................................... 9
GENERAL FEATURES OF MONITORING DURING ANESTHESIA .................................................................................. 9
CENTRAL VENOUS PRESSURE MONITORING .......................................................................................................... 10
PULMONARY ARTERY CATHETER............................................................................................................................ 10
CAPNOGRAM .......................................................................................................................................................... 11
ANESTHETIC COMPLICATIONS .................................................................................................................................... 11
AIR EMBOLISM........................................................................................................................................................ 11
RESPIRATORY COMPLICATIONS .............................................................................................................................. 11
MALIGNANT HYPERTHERMIA ................................................................................................................................. 12
INTRAOPERATIVE AND POSTOPERATIVE COMPLICATIONS .................................................................................... 12
RESUSCITATION....................................................................................................................................................... 13
MENDELSON SYNDROME........................................................................................................................................ 13
HYPOTHERMIA IN ANESTHESIA............................................................................................................................... 14
CLINICAL ANESTHESIA................................................................................................................................................. 14
HISTORY OF ANESTHESIA........................................................................................................................................ 14
STAGES OF ANESTHESIA.......................................................................................................................................... 14
PREANESTHETIC ASSESSMENT................................................................................................................................ 14
PEDIATRIC ANESTHESIA .......................................................................................................................................... 15
3. ANESTHESIOLOGY
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2ANESTHESIOLOGY INSTRUMENTS
ANESTHESIA IN HEAD INJURY ................................................................................................................................. 15
CARDIOVASCULAR ANESTHESIA.............................................................................................................................. 15
ANESTHESIA IN ENT ................................................................................................................................................ 16
OBSTETRIC ANESTHESIA.......................................................................................................................................... 16
ANESTHESIA IN ORTHOPEDICS................................................................................................................................ 16
RESPIRATORY ANESTHESIA ..................................................................................................................................... 16
DAY CARE ANESTHESIA ........................................................................................................................................... 17
DRUGS OF ANESTHESIA .............................................................................................................................................. 17
PREANESTHETIC DRUGS.......................................................................................................................................... 17
GENERAL FEATURES OF ANESTHETIC DRUGS ......................................................................................................... 17
INHALATIONAL ANESTHETICS ..................................................................................................................................... 18
MINIMUM ALVEOLAR CONCENTRATION................................................................................................................ 18
PARTITION COEFFICIENT......................................................................................................................................... 18
GENERAL FEATURES OF INHALATIONAL ANESTHETICS........................................................................................... 18
XENON..................................................................................................................................................................... 19
NITROUS OXIDE....................................................................................................................................................... 19
TRILENE ................................................................................................................................................................... 20
ETHER...................................................................................................................................................................... 20
HELIUM ................................................................................................................................................................... 20
CHLOROFORM......................................................................................................................................................... 20
HALOTHANE............................................................................................................................................................ 20
ENFLURANE............................................................................................................................................................. 21
ISOFLURANE............................................................................................................................................................ 22
DESFLURANE ........................................................................................................................................................... 22
SEVOFLURANE......................................................................................................................................................... 22
METHOXYFLURANE................................................................................................................................................. 23
INTRAVENOUS ANESTHETICS...................................................................................................................................... 23
GENERAL FEATURES OF INTRAVENOUS ANESTHETICS ........................................................................................... 23
PROPOFOL............................................................................................................................................................... 24
KETAMINE ............................................................................................................................................................... 24
THIOPENTONE......................................................................................................................................................... 25
ETOMIDATE............................................................................................................................................................. 26
LOCAL ANESTHETICS ................................................................................................................................................... 26
GENERAL FEATURES OF LOCAL ANESTHETICS......................................................................................................... 26
4. ANESTHESIOLOGY
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3ANESTHESIOLOGY INSTRUMENTS
BUPIVACAINE .......................................................................................................................................................... 28
LIGNOCAINE............................................................................................................................................................ 28
PRILOCAINE............................................................................................................................................................. 29
COCAINE.................................................................................................................................................................. 29
PROCAINE................................................................................................................................................................ 29
BIER’S BLOCK/IVRA ................................................................................................................................................. 29
PERIBULBAR AND RETROBULBAR BLOCK................................................................................................................ 30
STELLATE GANGLION BLOCK................................................................................................................................... 30
BRACHIAL PLEXUS BLOCK........................................................................................................................................ 30
CELIAC PLEXUS BLOCK............................................................................................................................................. 30
NEUROMUSCULAR BLOCKERS .................................................................................................................................... 31
GENERAL FEATURES OF NEUROMUSCULAR BLOCKERS.......................................................................................... 31
DEPOLARISING MUSCLE RELAXANTS – SUCCINLY CHOLINE ................................................................................... 31
FEATURES OF NON DEPOLARIZING MUSCLE BLOCKERS......................................................................................... 33
D-TUBOCURARINE................................................................................................................................................... 33
PANCURONIUM ...................................................................................................................................................... 33
VECURONIUM ......................................................................................................................................................... 34
MIVACURIUM.......................................................................................................................................................... 34
ATRACURIUM.......................................................................................................................................................... 34
GALLAMINE............................................................................................................................................................. 34
ALCURONIUM ......................................................................................................................................................... 35
SPINAL, EPIDURAL AND CAUDAL ANESTHESIA and pain management ...................................................................... 35
SPLANCHNIC BLOCK ................................................................................................................................................ 35
NEURAXIAL BLOCKADE............................................................................................................................................ 35
SPINAL ANESTHESIA................................................................................................................................................ 35
EPIDURAL ANESTHESIA ........................................................................................................................................... 37
CAUDAL ANESTHESIA.............................................................................................................................................. 37
OTHER BLOCKS........................................................................................................................................................ 38
PAIN ............................................................................................................................................................................ 38
GENERAL FEATURES OF PAIN.................................................................................................................................. 38
ASSESSMENT OF PAIN............................................................................................................................................. 38
ANALGESIC DRUGS.................................................................................................................................................. 39
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4ANESTHESIOLOGY INSTRUMENTS
ANESTHESIOLOGY INSTRUMENTS
GENERAL FEATURES OF ANESTHETIC INSTRUMENTS
Rotameter Constant pressure, variable orifice, flow meter for gases
and liquids
Rotameter Height of bobbin rise indicates flow rate
MC cause of inaccurate reading in Rotameter 1
st
Static Electricity, 2
nd
Dirt
Wright spirometer Used for calculation of expired volumes
Types of Pneumatographs measuring airway resistance Fleisch’s type, Venturi type, Turbine type
Used to protect airway LMA, endotracheal tube, combitube
Least damage to blood elements Membrane oxygenator
ANESTHETIC CYLINDERS
Filling ratio of anesthetic cylinder Filling ratio is the weight of the fluid in
the cylinder divided by weight of water
required to fill the cylinder
Color of oxygen cylinder Black cylinder with white shoulders
Color of ethylene cylinder Purple
Color of nitrous oxide cylinder Blue
Color of cyclopropane cylinder Orange
PIN INDEX
Pin index of nitrous oxide 3,5
Pin index Pin is present on machine, not effective if wrong gas is
filled in cylinder, hole position on cylinder valves
System preventing Incorrect gas Cylinder attachment Pin Index Safety system
ANESTHETIC GASES
Gas filled as liquid in cylinders CO2, N20, cyclopropane
Gas stored in liquid form N2O
Nitrous oxide Cylinder blue in color, MAC 105
Tare weight is used for Gas Cylinders
For high pressure storage of gases, cylinders are made
of
Molybdenum steel
Pressure of N2O at 20*C 745 psi
High pressure in gas cylinder indicate Impurities in N2O
Critical temperature of air -140.6*C
Critical temperature of oxygen -119*C
Critical temperature of N2O 36.5*C
6. ANESTHESIOLOGY
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5ANESTHESIOLOGY INSTRUMENTS
ANESTHETIC MACHINES AND CIRCUITS
Anesthesia breathing circuit Cylinder is a part of high pressure system, O2 flush
delivers < 35 liters
Boyle’s machine Continuous flow, low resistance
Boyle’s law At constant temperature, volume of a given mass varies
inversely with its absolute pressure
High pressure system in anesthesia machine is delivered
by
Hanger yoke
Principle of Boyle’s apparatus Continuous Flow
Heidbrink meter in Boyle’s apparatus Indicates flow of gases
Bernoulli principle In laminar flow, velocity of flow through a tube is
inversely related to its pressure against the size of tube
Modified bernoulli Pressure change = 4 * (velocity)^2
Clayton is used in closed breathing circuit as Indicator
MAPLESON SYSTEM
Most efficient anesthetic circuit for GA with
spontaneous respiration
Mapleson A
Air flow in Magill’s circuit (Mapleson A) Equal to minute volume
Magill’s circuit Ideal for adults, semiclosed, spontaneous breathing is
must
NOT suited for both controlled and assisted ventilation Mapleson A
No corrugated tube in Mapleson C
Bain circuit Mapleson type D, can be used for both controlled and
spontaneous ventilation
Bain circuit Inner tube for inspiration, circuit of
choice for controlled ventilation, light
weight, fresh gas flow should be 1.5 times of
minute volume
Mapleson system used in children Ayer T tube
Ayre’s T piece Mapleson E
Features of Ayre’s T piece No reservoir bag, no expiratory valve
Most appropriate circuit for ventilating spontaneously
breathing infant during anesthesia
Jackson Ree’s modification of Ayre’s T piece
Rebreathing prevention valve Light, well designed, used at expiratory end of tube
Rebreathing circuit To and fro circuit, circle system, water system
OXYGEN CONTROL DEVICES
Assessment of oxygen in a cylinder attached to
anesthesia machine
Bourdon pressure gauge
Used for proper oxygen flow to patient Proportionator between N2O and O2 control valve,
different pin index, calibrated oxygen corrected analysis
System Maintaining O2 concentration by limiting N2O
flow
Pneumatic Interlock Oxygen Ratio Monitor Controller
(ORMC)
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6ANESTHESIOLOGY INSTRUMENTS
System Maintaining 25% O2 concentration and
Maximum N2O:O2 flow ratio of 3:1
Link 25 Proportion Limiting system(Datex Ohmeta
System)
Safety measures to prevent delivery of hypoxic mixture
to patient
Location of oxygen valve after N2O valve, location of fail
safe valve downstream from nitrous oxide supply
source
Oxygen concentrator Zeolite activation, delivers O2,requires power supply
Oxygen content in anesthetic mixture 33%
Fixed performance oxygen provided by Venturi mask
Delivery of oxygen in basic life support Through mask
Humidification of air is needed in Face mask
Oxygen delivery regulated by Oxygen tent, oxygen apparatus, poly mask, venti mask
Maximum O2 concentration achieved in venturi mask 60%
Side effects of oxygen therapy Absorption atelectasis, decreased pulmonary
compliance, decreased vital capacity, endothelial
damage
Oxygen given during anesthesia to prevent Hypoxia
90% oxygen by Non rebreathing mask
Safe oxygen concentration in therapy is to achieve PaO2 > 50 mm Hg
Humidity of dry 100% oxygen 0 mg H2O litre
Artificial nose Heat and moisture exchanger
DEVICES FOR CO2 ABSORPTION
CuSO4 present in Amsorb
Ba (OH)2 present in Baralime
Decrease CO2 absorption High flow, medium granule, No resistance in circuit
Decreases CO2 absorption Increased tidal volume, increased dead
space
Increases CO2 absorption Resistance in circuit
Soda lime is used to absorb CO2 in Closed circuit system
Reacts with soda lime Trilene
Main component of soda lime in closed circuit Calcium hydroxide
Composition of soda lime 90% Ca(OH)2 + 5% NaOH + 1% KOH
NOT a component of sodalime Ba OH2
Soda lime does NOT contain CaCl
NOT true about soda lime Used in treatment of alkalosis
Water is used for hardening in Soda lime
Color change in Mimoza 2 Red to white
Signs of soda lime exhaustion Change of color of granules, rise in ETCO2
in capnography, rise in BP followed by
fall, rise in pulse rate, deepening of
spontaneous respiration, increased oozing
from wound, increased sweating
DEAD SPACE
Normal dead space 30% of tidal ventilation
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7ANESTHESIOLOGY INSTRUMENTS
Anatomical dead space is increased by Atropine, Halothane, Inspiration
Dead space is increased by Anti cholinergic drugs, standing, hyperextension of neck
Physiological dead space is decreased by Neck flexion
Anatomical dead space in Supine position Decreases
Anatomical dead space decreased by Massive pleural effusion
Dead space NOT increased by Endotracheal intubation
Least amount of CO2 present in Anatomical dead space - end inspiration phase
ENDOTRACHEAL TUBE
Size of endotracheal tube in 1 – 6 months
aged
2 – 4 mm
Size of endotracheal tube in 6 months to 1
year aged
3.5 – 4.5 mm
Size of endotracheal tube in 1 – 6 years [Age/3] + 3.5
Size of endotracheal tube more than 6
years
[Age/4] + 4.5
Length of endotracheal tube in neonate 10 – 11 cm
Length of endotracheal tube in elder
children
[age/2] + 12
Reasonable size of endotracheal tube in 3 year old 4.5 mm
Curved blade in adult laryngoscope is Macintosh
Endotracheal cuff High volume low pressure, low volume high pressure
Size of endotracheal tube in children less than 6 years (Age/3.5)+3.5
Diameter and length of endotracheal tube in full term
infant
3.5 mm and 12 mm
McIntosh tube for Adults
Magill’s tube Children
Armoured endotracheal tube is used in Neurosurgery
RAE endotracheal tube Red
RAE tube is used in LASER surgery
Diameter of ET tube in child less than 1000 g 2.5,3
Direct laryngoscope in right handed person Left hand
Type of endotracheal tube and blade in children Uncuffed tube with straight blade
Cuff pressure in ET tube should not exceed 23 mm Hg
LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION
High airway resistance seen in Main bronchus
Airway assessment Mallampatti grading, Cormack and
Lehare (based on laryngoscopy), Wilson’s
scoring, LEMON law
LEMON law Look externally, evaluate 3-3-2 rule,
Mallampatti, Obstruction, Neck mobility
Normal thyromental distance >6.5 cm
Mallampatti grading for Inspection of oral cavity before intubation
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8ANESTHESIOLOGY INSTRUMENTS
Mallampatti classification is based on Opening of mouth
Clinical predictor of a difficult intubation
is postulated to be responsible for a grade
III Mallampatti view of oral cavity
Large tongue
NOT an indication for endotracheal intubation Pneumothorax
Both orotracheal and nasotracheal intubation is
contraindicated in
Acute laryngotracheobronchitis
Difficulty in intubation Burns in head and neck, Still’s disease, Down’s
syndrome
Features of difficult airway Miller’s sign, TMJ ankylosis, micrognanthia and
macroglossia
Used in difficult intubation Helium O2 mixture, entoxon, sevoflurane
Maneuver performed during laryngoscopy and
intubation
Flexion of neck, extension of head at atlantooccipital
joint, in straight blade laryngoscope epiglottis is lifted
by tip, upper incisors are most vulnerable to damage by
laryngoscopy so laryngoscope should not be levered
against them
Endotracheal intubation in children Small morbidity on prolonged intubation
NOT seen during laryngoscopy Hypotension
Sellick’s original description of cricoid
pressure
Extending head
Sellick maneuver is used to prevent Gastric aspiration
Sellick maneuver is effective in prevention
of
Passive regurgitation and subsequent
aspiration
NOT a maneuver performed during laryngoscopy Laryngoscope is lifted upwards levering over the upper
incisors
Effective adjuvant in attenuating
hypertension and tachycardia associated
with laryngoscopy and intubation
Succinylcholine
High potassium level with scoline for
intubation occurs with
Chronic paraplegia
Most accurate measurement of correct placement of ET
tube
End Tidal CO2
Correct placement of endotracheal tube judged by Arterial CO2, Breath sounds, Chest X ray
Speedy intubation, breath sounds were observed to be
decreased on left side and high end tidal CO2
Endobronchial intubation
Laryngoscopy and intubation is associated with Hypertension and tachycardia, raised IOT, raised ICT,
decreased lower esophageal sphincter tone, arrhythmia
Endotracheal intubation Reduces normal anatomical dead space
A child has been intubated and connected to anesthesia
machine. A problem has occurred in anesthesia
machine and the child collapsed after 2 minutes. What
to do next
Increase the flow
Laryngeal complication of Prolonged ET intubation Stenosis, Ulceration, Abductor paralysis
Prevention of intubation induced
laryngeal spasm
Local anesthesia, fentanyl, diltiazem
Drug that can precipitate reflux Promethazine
Treatment of severe tracheal stenosis due to
endotracheal intubation for more than 2 weeks
Tracheal resection and end to end anastomosis
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9ANESTHESIOLOGY INSTRUMENTS
Surgery for extensive tracheal stenosis Grillo or Barclay procedure
NASOTRACHEAL INTUBATION
Merits of nasotracheal intubation Good oral hygiene
Nasal intubation is contraindicated in CSF rhinorrhoea
LARYNGEAL MASK AIRWAY
Supraglottic type of airway management Laryngeal mask airway
NOT a definite airway Laryngeal mask apparatus
NOT an advantage of laryngeal mask airway Aspiration is prevented
Laryngeal mask airway NOT used for Large tumor in oral cavity
Laryngeal mask airway is used for Maintenance of airway
Laryngeal mask airway More reliable than face mask, alternative to
endotracheal tube, does NOT require laryngoscope and
visualization
LMA Intubation can be done, size 1 for neonates, size 3 for
adults
Plan C of anesthetic airway management Insertion of laryngeal mask airway and fibroptic
bronchoscopy
TRENDELENBERG POSITION
Maximum vital capacity decreased in Trendelenberg position
Trendelenberg position decrease Vital capacity, FRC, compliance
Trendelenberg position does NOT cause decrease in Respiratory rate
Position with least vital capacity in GA Trendelenberg
GENERAL FEATURES OF MONITORING DURING ANESTHESIA
Individual operative awareness by Bispectral imaging
Organ at greatest risk of ischemia under
conditions of normovolemic hemodilution
Heart
Best to monitor intraoperative myocardial ischemia Transesophageal echocardiography
Most sensitive and practical technique to detect
myocardial ischemia in perioperative period
Regional wall motion abnormality detected with help of
2D transesophageal echocardiography
5th
vital sign Pulse oximetry
Pulse oximetry At 660 nm, oxyhemoglobin reflect more light than
deoxyhemoglobin, reverse is true at 940 nm
Pulse oximetry detects inaccurately in presence of Nail polish, methemoglobinemia, skin pigmentation
Inadequate ventilation during intraoperative period is
best assessed by
Pulse oximetry
Beer Lambert Law Pulse oximetry
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10ANESTHESIOLOGY INSTRUMENTS
Oxygen saturation is measured by Pulse oximeter
Used to monitor respiration in non intubated neonate Impedance pulmonometry
Non ventilated baby is in incubator, best way to
monitor baby’s breathing and detect apnea
Impedance pulmonometry
A postoperative patient with pH 7.25 MAP 60 mm Hg
treated with
Fluid therapy with CVP monitoring
Least affected during anesthesia Brainstem auditory evoked potential
Somatosensory evoked potential is
important during
Thoracic and abdominal aorta surgery
MC nerve used for monitoring during anesthesia Ulnar nerve
Modality best utilized for neuromuscular
monitoring during maintenance of
anesthesia
Train of four
NOT a cause of bacterial sepsis in ICU patient on
invasive monitoring
Humidified air
CENTRAL VENOUS PRESSURE MONITORING
MC vein for CVP monitoring Right Internal Jugular Vein
While inserting CVP, patient developed respiratory
distress
Pneumothorax
MC complication of central venous catheter Catheter related infection
Complications of CVP line Airway injury, hemothorax, septicemia, air embolism,
pulmonary edema
CVP monitoring is most useful in Guiding hemodynamic therapy
In a patient with multisystem trauma, presence of
hypotension with elevated CVP is suggestive of
Cardiopulmonary problem
CVP does NOT indicate Tissue perfusion
PULMONARY ARTERY CATHETER
Swan Ganz catheter measure PCWP, mixed venous oxygen saturation, Right atrial
pressure
While introducing Swan Ganz catheter, its placement in
pulmonary artery can be identified by
PA pressure tracing has dicrotic notch from closure of
pulmonary valve > diastolic pressure is higher in PA
than in RV
Swan Ganz catheter is used to measure Pulmonary artery pressure, pressure of
cardiac chambers, pulmonary capillary
wedge pressure, cardiac output and
cardiac index, blood sample for mixed
venous oxygen saturation, to measure
temperature of pulmonary artery
Pulmonary wedge pressure is indirectly Left atrial pressure
Measurement of intravascular pressure by pulmonary
artery catheter
At the end of expiration
Left atrial filling pressure closely
resembles
Pulmonary capillary wedge pressure
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11ANESTHETIC COMPLICATIONS
CAPNOGRAM
Capnography is based on Luft principle
NOT a cardiovascular monitoring technique Capnogram
Flat capnogram Disconnection of anesthetic tubing, accidental
extubation, mechanical ventilation failure
Phases of capnogram Phase 0 – inspiratory phase, phase 1 – dead
space and little or no CO2, phase 2 –
mixture of alveolar and dead space gas,
phase 3 – alveolar plateau with peak
representing end expiratory and end tidal
CO2
ANESTHETIC COMPLICATIONS
AIR EMBOLISM
End tidal CO2 decreased during surgery Air embolism
Significant air embolism occurs with volume 100 cc
Diagnosing air embolism with tracheoesophageal
echocardiography
Very sensitive investigation, continuous monitoring to
detect venous embolism, interferes with Doppler when
used together
Factors favoring embolism is a patient with major
trauma
Mobility of fracture, diabetes
Air embolism in neurosurgery is maximum in Sitting position
Most sensitive investigation for air embolism Transesophageal echo > Doppler ultrasound
Known case of thyrotoxicosis posted for
abdominoperineal resection. sudden drop in BP and
end tidal CO2, Mill Wheel murmur
Air embolism
Most serious complication of sitting position Air embolism
Transesophageal echocardiography Can quantify the volume of air embolised, Very
sensitive investigation, Continuous monitoring is
needed to detect venous embolism
RESPIRATORY COMPLICATIONS
Anesthetic complication with respiratory infection Bacteremia, Increased mucosal bleeding, laryngospasm
Aspiration pneumonitis Affected by volume of aspiration and pH of aspiration
fluid, increased incidence during induction,
inflammation, infection
Obstruction of respiration in comatose patients is
mainly due to
Falling back of tongue
NOT a cause of respiratory insufficiency in immediate
post operative period
Mild hypovolemia