This document provides an overview of common communicable diseases and prevention efforts. It discusses objectives of understanding communicable diseases, knowing those common to a given area, and how to respond to outbreaks and prevent transmission. Examples of important communicable diseases covered include influenza, foodborne illnesses, tuberculosis, Lyme disease, and health care-associated infections. Prevention involves surveillance, immunizations, isolation, education, and addressing at-risk groups.
Vector-borne diseases are illnesses caused by pathogens and parasites in human populations. This presentation contains key facts about these diseases and global and European trends. WHO/Europe is making this presentation available to countries and partner organizations for use in their campaigns for World Health Day 2014.
Vector-borne diseases are illnesses caused by pathogens and parasites in human populations. This presentation contains key facts about these diseases and global and European trends. WHO/Europe is making this presentation available to countries and partner organizations for use in their campaigns for World Health Day 2014.
A basic introduction into the subject of health system preparedness for emerging and re-emerging infections, including the definitions of EIDs and preparedness, as well as, one of many conceptual frameworks for preparedness.
Infectious Diseases of Public Health Importance and the Benefits of Vaccinati...Stephen Olubulyera
Review of infectious diseases of public health important and the benefits of vaccinating medical & health practitioners and the subordinate staffs against the disease at a hospital setting
A basic introduction into the subject of health system preparedness for emerging and re-emerging infections, including the definitions of EIDs and preparedness, as well as, one of many conceptual frameworks for preparedness.
Infectious Diseases of Public Health Importance and the Benefits of Vaccinati...Stephen Olubulyera
Review of infectious diseases of public health important and the benefits of vaccinating medical & health practitioners and the subordinate staffs against the disease at a hospital setting
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Infectious diseases have been a part of human history for as long as we can remember. From the Black Death in the 14th century to more recent outbreaks like COVID-19, these diseases have shaped the course of our lives.
Infectious diseases have been a part of human history for as long as we can remember. From the Black Death in the 14th century to more recent outbreaks like COVID-19, these diseases have shaped the course of our lives.
this ppt is made by shrikrishna kesharwani , student of urban planning,4th year, Manit , Bhopal,
in this ppt, I have discussed how to do pandemic or epidemic management in detail.,
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
2. Objectives
• Understand the definition
• Know the common communicable diseases in
your area
• Know how healthcare professionals should
respond to outbreaks
• Know how to prevent your patients from
extracting these diseases
3. Definition
• Communicable diseases (infectious diseases)
are illnesses caused by bacteria, viruses, fungi
or parasites. Organisms that are
communicable may be transmitted from one
infected person to another or from an animal
to a human, directly or by modes such as
airborne, waterborne, foodborne, or
vectorborne transmission, or by contact with
an inanimate object, such as a contaminated
doorknob.
4. Communicable disease prevention and
control
• Involves the surveillance for and protection from:
• communicable diseases that may result from changes in or
evolution of infectious agents (bacteria, viruses, fungi or
parasites), spread of infectious agents to new geographic
areas or among new populations, persistence of infectious
agents in geographic areas and populations, newly
emerging infectious agents, or acts of bioterrorism.
• Communicable disease prevention and control involves
isolation and quarantine, immunization, prophylactic
(preventive) measures, early interventions including
antimicrobial treatment, public health education and other
measures.
5. Importance
• Communicable disease prevention and control is the cornerstone of
public health. Waves of severe illness and death due to
communicable diseases have occurred throughout history, including
smallpox prior to its eradication, the bubonic plague in 14th century
Europe, the influenza pandemic of 1918 and, close to home, the
massive waterborne outbreak of cryptosporidiosis in Milwaukee in
1993. Advancements in clean water and refrigeration and the
development of safe, effective vaccines have greatly decreased such
threats; however, common diseases still cause outbreaks and new
communicable diseases emerge. The worldwide AIDS epidemic,
multidrug-resistant tuberculosis, West Nile virus, severe acute
respiratory syndrome (SARS), avian influenza and drug-resistant
staphylococcus infections are all reminders of our continued
vulnerability to communicable diseases.
6. Vaccinations
• Vaccines protect more than the individual immunized;
they prevent the spread of disease within the
population. This is the principle of herd immunity. The
development of vaccines and their safe and effective
use are considered to be among the greatest medical
and public health achievements of the 20th century.
Many diseases that were widely associated with severe
or fatal outcomes are now rare in the U.S. because of
sound policies promoting widespread use and
application of vaccines, particularly routine use of
vaccines to prevent serious diseases among children
7. Response
• AIDS/HIV - which coordinates the state’s public health response to the
AIDS/HIV epidemic including surveillance and epidemiologic investigation;
HIV testing and referral, partner services, education and risk reduction
activities; case management and Ryan White funded care services; and
AIDS drug assistance and health insurance premium subsidy programs. It is
also responsible for Adult Hepatitis prevention and control.
• Communicable Disease Epidemiology - responsible for maintaining and
improving the surveillance system for communicable diseases. The section
has specific responsibility for the epidemiologic investigation and response
to tuberculosis, food/water/vector borne diseases, zoonotic diseases,
suspected communicable disease outbreaks, and emerging and re-
emerging diseases. It also provides infection control consultation to the
health care provider community and technical assistance on health risks
and health care needs of refugees and other populations arriving in the
United States.
8. • Immunization - responsible for preventing those communicable diseases for which
immunizations are available. The program provides vaccines and technical
assistance to health care providers, conducts surveillance and investigation of
vaccine preventable diseases, operates the Wisconsin Immunization Registry
designed to keep track of immunization histories for Wisconsin citizens, and
conducts educational activities to encourage prompt and complete immunization.
The section implements the state law that requires certain immunizations for
children entering day care centers and schools. It is also responsible for
Wisconsin’s use of the National Pharmaceutical Stockpile and conduct of mass
immunization/prophylaxis in the event of an emergency.
• Sexually Transmitted Diseases– responsible for prevention and control of five
reportable sexually transmitted diseases; coordinates the state’s public health
response to the STD epidemic including reporting, surveillance, epidemiologic
interviewing and investigation, screening, testing, treatment, partner referral and
partner services. The five reportable sexually transmitted diseases are chancroid,
Chlamydia trachomatis infection, gonorrhea, sexually transmitted pelvic
inflammatory disease, and syphilis. Statewide educational efforts are provided to
reduce risky sexual behavior and the risk of infection, and re-infection with
sexually transmitted diseases.
9. More communicable diseases
• Influenza
• Each year 5 percent to 20 percent of the
population gets sick from influenza. In Wisconsin
this annually results in thousands of hospitalizations
and several hundred deaths. Young children,
pregnant women, people with underlying medical
conditions and the elderly are at greatest risk for
influenza-related complications.
• Promoting annual influenza vaccination remains
the most effective means of reducing the
occurrence of influenza in Wisconsin.
10. • Foodborne diseases
• The Centers for Disease Control and Prevention estimates
that 76 million cases of foodborne disease occur each year in
the United States, resulting in 325,000 hospitalizations and
5,000 deaths.
• During 1998 to 2007, Wisconsin reported 260 foodborne
disease outbreaks, and each year the Wisconsin Division of
Public Health receives reports of thousands of individual cases
of infection from reportable foodborne pathogens including
Salmonella, Campylobacter, shigatoxin-producing E. coli, and
Listeria.
• Advances in laboratory testing methods have increased
capacity to detect foodborne illnesses and outbreaks.
11. Tuberculosis
• In Wisconsin the number of cases of active tuberculosis disease has
declined from an average of 111 per year during the 1990s to 71 per
year during the period 2000 to 2009.
• The occurrence of multidrug-resistant (MDR) tuberculosis is on the
rise, from a single reported case during 2000 to 2004, to 12 cases
during 2005 to 2009.
• The proportion of active disease cases occurring in people who were
foreign-born has also increased in Wisconsin.
• Active tuberculosis disease, whether multidrug-resistant or not,
occurs predominantly among minority populations. Of the 68 cases of
tuberculosis reported in Wisconsin during 2008, the race/ethnicity
among the patients was Asian, 35 percent; White nonHispanic, 26
percent; Blacks/African American, 19 percent; Hispanics/Latinos, 19
percent; and American Indian, 1 percent.
12. Lyme disease/tickborne infections
• Lyme disease is the most common vectorborne disease
in the United States. In Wisconsin the incidence of
Lyme disease has tripled from an average of 8 cases
per 100,000 during 1991 to 1995, to 27 cases per
100,000 during 2004 to 2008. This increase follows a
steady expansion in the geographic range of the deer
tick (Ixodes scapularis) which transmits Borrelia
burgdorferi, the bacteria that cause Lyme disease.
• Deer ticks are now found in most areas of Wisconsin
and, in addition to B.burgdorferi, can transmit bacteria
that cause other serious infections including
anaplasmosis, ehrlichiosis, and babesiosis.
13. Health care associated infections
• National estimates of annual health-care-
associated infections indicate that 5 percent to
10 percent of hospital patients acquire health-
care-associated infections, and such infections
rank among the top 10 causes of death.
Recognition of these infections as a major public
health problem has resulted in federal funding
for state health departments to develop health
care associated infection prevention programs