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PAIN PATHWAY OF OROFACIAL
REGION AND ITS INNERVATION TO
THE PERIODONTIUM
CONTENTS
 Introduction
 Classification
 Types
clinical
qualitative
 Orofacial pain
cause
pain pathway
 Innervation of periodontium
 conclusion
INTRODUCTION
 Pain refers to an unpleasant sensory and emotional experience
associated with actual or potential tissue damage
 It is a protective mechanism of the body Whenever any tissue is
being damaged and it causes the individual to react to remove the
pain stimulus
ACUTE
/TRAUMATIC PAIN
SOMATIC PAIN
SUPERFICIAL
PAIN
DEEP PAIN
VISCERAL PAIN
CHRONIC PAIN
NON MALIGNANT OR
BENIGN PAIN
MUSCULOSKELETAL
PAIN
NEUROPATHIC
PAIN
MALIGNANT OR
CANCER PAIN
BASED ON
SOURCE /
LOCATION/REFER
RAL/DURATION
CLINICAL TYPES OF PAIN
 Somatic pain
 Visceral pain
 Referred pain
 Radiating pain
 Projected pain
 Hyperalgesia
QUALITATIVE TYPES OF PAIN SENSATION
FAST PAIN
 Felt about 0.1 sec after a pain
stimulus is applied
 Sharp, pricking , acute ,
electric pain
 Fast sharp pain is not felt in
most deeper tissues of the body
 Seen in A delta fibers
SLOW PAIN
 Usually begins after 1sec or
more and may range from
seconds to minutes
 Slow , burning , aching ,
throbbing , nauseous and
chronic pain
 Associated with tissue
destruction
 Seen in C fibers
OROFACIAL PAIN
 Any pain which is felt in the mouth , jaw , and the face and these
pain sensations are carried by the trigeminal nerve
 Also used to describe the pain in the region above the neck, in front
of the ears and below the orbitomental as well as pain in the oral
cavity
CAUSES OF ORO FACIAL PAIN
 Dental
 Facial bone disease ( infective,traumatic,neoplastic)
 Pathology in related structures(salivary gland ,sinus)
 Neurological disorder (trigeminal neuralgia , glossopharyngeal ,
occipital,post herpetic neuralgia)
 Vascular(migraine,cluster headache,temporal arteritis)
 Psychogenic pain( atypical facial pain , atypical odontalgia,burning mouth
syndrome)
 Refferred (MI and angina)
NOCICEPTORS
 Receptors that are sensitive to painful stimulus and are responsible
for initiating the generation of pain
 It is a free nerve ending found in almost all tissues
 Identifies tissue injuries and responds to multiple stimulus
 These free nerve ending(nociceptors) are attached to the first order
neuron
ORGANISATION OF SENSORY
PATHWAY
FIRST ORDER
SECOND ORDER
THIRD ORDER
 FIRST ORDER NEURONS
 These are the cells in the posterior nerve root ganglia , receive impulses from pain
receptors through dendrites
 These impulses are transmitted through the axons to spinal cord
 Impulses are transmitted by A delta and C fibres
Type A fibers
 alpha
 beta
 gamma
 delta
type c fibers
Carry tactile and proprioceptive impulse and
not pain
Carries pain sensation pricking pain is
carried by A delta and dull aching burning
is carried by c fibers
A DELTA FIBERS
 Responsible for temperature and fast or first
pain
 Faster with conduction velocity of 12-45
m/sec
 Myelinated
 Sharp pain
 Localized pain
 Lasts for short while
 Withdrawl reflex
C FIBERS
 Responsible for slow or second pain ,
temperature
 Much slower with conduction velocity of
0.2-2.0m/sec
 Odontogenic pain is associated with C
fibers
 Unmyelinated
 throbbing , burning , dull pain
 Poorly localized
 diffused
SECOND ORDER NEURON
 The neurons of marginal nucleus and substantia gelatinosa form second order
neurons
 Fibers from these neurons ascend in the form of lateral spinothalamic tract
 Fibers of A delta arise from neurons of the marginal nucleus
 Fibers of C arise from neurons of substantia gelatinosa
THIRD ORDER NEURONS
 The neurons of pain pathway are the neurons in thalamic nucleus , reticular
formation , tectum and gray matter
 Axons from these neurons reach the sensory area of cerebral cortex or
hypothalamus
Peripheral pain receptors
A delta and c fibers
First order neurons of the dorsal root ganglia
Spinal cord
A delta synapse with marginal cells of grey
horn and c fibers synapse with SG of posterior
grey horn
Second order neuron cross to the opposite side
and ascends as lateral spinothalamic tract
Lateral spinothalamic tract continues as spinal
lemniscus in the brain stem and ends in the
VPL nucleus of thalamus
The third order neurons start at the thalamus
and via the internal capsule reach areas 3,1,2
of primary sensory cortex
PAIN IN OROFACIAL REGION
ODONTOGENIC PAIN
 refers to pain initiating from the teeth or their
supporting structures i.e mucosa , gingivae ,
maxilla , mandible or periodontal membrane
APICAL PAIN
 Caused by infection spreading through the apical foramen of the tooth into
apical periodontal region causing inflammation ( apical periodontitis ) and
ultimately a dental abscess if left untreated
PERICORONITIS
 Pain commonly arises from the supporting gingivae and mucosa
when infection arises from an erupting tooth ( teething or
pericoronitis ) this is the most common cause for the removal of the
third molar teeth ( wisdom teeth ) the pain may be constant or
intermittent but is often evoked when biting down with opposite
teeth
INNERVATION OF PERIODONTIUM
 Innervation of periodontium and nerve supply of periodontal tissues occurs
through the branches of trigeminal nerve
 Trigeminal nerves have motor sensory and intermediated roots which are
mounted directly to the brain
 Nerve receptors in the gums , alveolar bone , and periodontal ligament helps to
feel pain , touch and pressure
 nerves in the periodontal ligament provides information about the movement
and position of teeth
 Innervation gums maxillary arch are supplied by superior alveolar
nerves , infraorbital nerve , and palatine branch of nasopalatine
nerve- a branch of second divisions of trigeminal nerve (
maxillary nerve)
 Innervation teeth and periodontal ligament
maxillary arch are supplied by superior
alveolar nerves
 Innervation gums mandibular arch are supplied by mental nerve ,
sublingual branch of lingual nerve - a branch of third divisions of
trigeminal nerve ( mandibular nerve)
 Innervation teeth and periodontal ligament
mandibular arch are supplied by lower
alveolar nerve
CONCLUSION
 Pain although unpleasant , is a protective sensation . The
most important part of managing pain is understanding
the problem and cause of pain and also through the
proper diagnosis and appropriate therapy

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pain pathway.pptx

  • 1. PAIN PATHWAY OF OROFACIAL REGION AND ITS INNERVATION TO THE PERIODONTIUM
  • 2. CONTENTS  Introduction  Classification  Types clinical qualitative  Orofacial pain cause pain pathway  Innervation of periodontium  conclusion
  • 3. INTRODUCTION  Pain refers to an unpleasant sensory and emotional experience associated with actual or potential tissue damage  It is a protective mechanism of the body Whenever any tissue is being damaged and it causes the individual to react to remove the pain stimulus
  • 4. ACUTE /TRAUMATIC PAIN SOMATIC PAIN SUPERFICIAL PAIN DEEP PAIN VISCERAL PAIN CHRONIC PAIN NON MALIGNANT OR BENIGN PAIN MUSCULOSKELETAL PAIN NEUROPATHIC PAIN MALIGNANT OR CANCER PAIN BASED ON SOURCE / LOCATION/REFER RAL/DURATION
  • 5. CLINICAL TYPES OF PAIN  Somatic pain  Visceral pain  Referred pain  Radiating pain  Projected pain  Hyperalgesia
  • 6. QUALITATIVE TYPES OF PAIN SENSATION FAST PAIN  Felt about 0.1 sec after a pain stimulus is applied  Sharp, pricking , acute , electric pain  Fast sharp pain is not felt in most deeper tissues of the body  Seen in A delta fibers SLOW PAIN  Usually begins after 1sec or more and may range from seconds to minutes  Slow , burning , aching , throbbing , nauseous and chronic pain  Associated with tissue destruction  Seen in C fibers
  • 7. OROFACIAL PAIN  Any pain which is felt in the mouth , jaw , and the face and these pain sensations are carried by the trigeminal nerve  Also used to describe the pain in the region above the neck, in front of the ears and below the orbitomental as well as pain in the oral cavity
  • 8. CAUSES OF ORO FACIAL PAIN  Dental  Facial bone disease ( infective,traumatic,neoplastic)  Pathology in related structures(salivary gland ,sinus)  Neurological disorder (trigeminal neuralgia , glossopharyngeal , occipital,post herpetic neuralgia)  Vascular(migraine,cluster headache,temporal arteritis)  Psychogenic pain( atypical facial pain , atypical odontalgia,burning mouth syndrome)  Refferred (MI and angina)
  • 9. NOCICEPTORS  Receptors that are sensitive to painful stimulus and are responsible for initiating the generation of pain  It is a free nerve ending found in almost all tissues  Identifies tissue injuries and responds to multiple stimulus  These free nerve ending(nociceptors) are attached to the first order neuron
  • 10. ORGANISATION OF SENSORY PATHWAY FIRST ORDER SECOND ORDER THIRD ORDER
  • 11.  FIRST ORDER NEURONS  These are the cells in the posterior nerve root ganglia , receive impulses from pain receptors through dendrites  These impulses are transmitted through the axons to spinal cord  Impulses are transmitted by A delta and C fibres
  • 12. Type A fibers  alpha  beta  gamma  delta type c fibers Carry tactile and proprioceptive impulse and not pain Carries pain sensation pricking pain is carried by A delta and dull aching burning is carried by c fibers
  • 13. A DELTA FIBERS  Responsible for temperature and fast or first pain  Faster with conduction velocity of 12-45 m/sec  Myelinated  Sharp pain  Localized pain  Lasts for short while  Withdrawl reflex C FIBERS  Responsible for slow or second pain , temperature  Much slower with conduction velocity of 0.2-2.0m/sec  Odontogenic pain is associated with C fibers  Unmyelinated  throbbing , burning , dull pain  Poorly localized  diffused
  • 14. SECOND ORDER NEURON  The neurons of marginal nucleus and substantia gelatinosa form second order neurons  Fibers from these neurons ascend in the form of lateral spinothalamic tract  Fibers of A delta arise from neurons of the marginal nucleus  Fibers of C arise from neurons of substantia gelatinosa
  • 15. THIRD ORDER NEURONS  The neurons of pain pathway are the neurons in thalamic nucleus , reticular formation , tectum and gray matter  Axons from these neurons reach the sensory area of cerebral cortex or hypothalamus
  • 16. Peripheral pain receptors A delta and c fibers First order neurons of the dorsal root ganglia Spinal cord A delta synapse with marginal cells of grey horn and c fibers synapse with SG of posterior grey horn Second order neuron cross to the opposite side and ascends as lateral spinothalamic tract Lateral spinothalamic tract continues as spinal lemniscus in the brain stem and ends in the VPL nucleus of thalamus The third order neurons start at the thalamus and via the internal capsule reach areas 3,1,2 of primary sensory cortex
  • 17. PAIN IN OROFACIAL REGION ODONTOGENIC PAIN  refers to pain initiating from the teeth or their supporting structures i.e mucosa , gingivae , maxilla , mandible or periodontal membrane
  • 18. APICAL PAIN  Caused by infection spreading through the apical foramen of the tooth into apical periodontal region causing inflammation ( apical periodontitis ) and ultimately a dental abscess if left untreated
  • 19. PERICORONITIS  Pain commonly arises from the supporting gingivae and mucosa when infection arises from an erupting tooth ( teething or pericoronitis ) this is the most common cause for the removal of the third molar teeth ( wisdom teeth ) the pain may be constant or intermittent but is often evoked when biting down with opposite teeth
  • 20. INNERVATION OF PERIODONTIUM  Innervation of periodontium and nerve supply of periodontal tissues occurs through the branches of trigeminal nerve  Trigeminal nerves have motor sensory and intermediated roots which are mounted directly to the brain  Nerve receptors in the gums , alveolar bone , and periodontal ligament helps to feel pain , touch and pressure  nerves in the periodontal ligament provides information about the movement and position of teeth
  • 21.  Innervation gums maxillary arch are supplied by superior alveolar nerves , infraorbital nerve , and palatine branch of nasopalatine nerve- a branch of second divisions of trigeminal nerve ( maxillary nerve)  Innervation teeth and periodontal ligament maxillary arch are supplied by superior alveolar nerves
  • 22.  Innervation gums mandibular arch are supplied by mental nerve , sublingual branch of lingual nerve - a branch of third divisions of trigeminal nerve ( mandibular nerve)  Innervation teeth and periodontal ligament mandibular arch are supplied by lower alveolar nerve
  • 23. CONCLUSION  Pain although unpleasant , is a protective sensation . The most important part of managing pain is understanding the problem and cause of pain and also through the proper diagnosis and appropriate therapy