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OSTEOPOROSIS
By Rosemarie Carpio
What is Osteoporosis?
■ Most common metabolic bone disease.
■ It results from the loss of calcium in the bones, causing the bones to become brittle and
susceptible to breaking.
■ "porous bone" "silent disease" because it is usually not diagnosed until the person suffers a
fracture, or broken bone.
■ Risk:Women (Menopausal Period); Increasing age, lifestyle, genes (Asian), medication
(corticosteroid)
ASSESSMENT:
■ Back pain, caused by a fractured or collapsed vertebra
■ Loss of height over time
■ A stooped posture
■ A bone fracture that occurs much more easily than expected: thoracic and lumbar spine,
hip fractures, and Colles’ fractures of the wrist –First clinical manifestation of Osteoporosis
MANAGEMENT and INTERVENTION
■ A diet rich in calcium and vitamin D throughout life (eg, cheese and other dairy
products, steamed broccoli, canned salmon with bones) daily.
■ Regular weight-bearing exercise promotes bone formation (20 to 30 min aerobic
exercise for 3 or more in a week)
PHARMACOLOGIC:
■ Calcium andVit. D supplements –first line meds for treatment and prevention
– Caltrate (calcium carbonate)
• taken with meals or with a beverage high in vitamin C to promote absorption
• Increase fluid intake (because calcium supp.Common side effects are abdominal
distention and constipation)
Miacalcin, Fortical (calcitonin)
– Take meds exactly as directed
– Report allergy to salmon or other seafood
– Diet should be high in calcium and vitamin D.
– Alternate nares daily when using nasal spray to avoid nosebleeds
– Weight-bearing exercise is beneficial for treatment of osteoporosis
Fosamax (alendronate) or Actonel (risedronate)
– Take the medication first thing in the morning 30 min. before other medication,
beverages, food and remain upright for 30-60min
– Engage in wt.-bearing exercise
– Assess Ca+ and phosphate levels for baseline and during therapy
Evista (raloxifene)
– Take as directed; bone pain should be reported
– Engage in regular wt.-bearing exercise
– Report leg pain (DVT)
– May cause hot flashes or induce ovulation
– Monitor wt. weekly; report wt. gain

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Osteoporosis

  • 2. What is Osteoporosis? ■ Most common metabolic bone disease. ■ It results from the loss of calcium in the bones, causing the bones to become brittle and susceptible to breaking. ■ "porous bone" "silent disease" because it is usually not diagnosed until the person suffers a fracture, or broken bone. ■ Risk:Women (Menopausal Period); Increasing age, lifestyle, genes (Asian), medication (corticosteroid) ASSESSMENT: ■ Back pain, caused by a fractured or collapsed vertebra ■ Loss of height over time ■ A stooped posture ■ A bone fracture that occurs much more easily than expected: thoracic and lumbar spine, hip fractures, and Colles’ fractures of the wrist –First clinical manifestation of Osteoporosis
  • 3. MANAGEMENT and INTERVENTION ■ A diet rich in calcium and vitamin D throughout life (eg, cheese and other dairy products, steamed broccoli, canned salmon with bones) daily. ■ Regular weight-bearing exercise promotes bone formation (20 to 30 min aerobic exercise for 3 or more in a week) PHARMACOLOGIC: ■ Calcium andVit. D supplements –first line meds for treatment and prevention – Caltrate (calcium carbonate) • taken with meals or with a beverage high in vitamin C to promote absorption • Increase fluid intake (because calcium supp.Common side effects are abdominal distention and constipation)
  • 4. Miacalcin, Fortical (calcitonin) – Take meds exactly as directed – Report allergy to salmon or other seafood – Diet should be high in calcium and vitamin D. – Alternate nares daily when using nasal spray to avoid nosebleeds – Weight-bearing exercise is beneficial for treatment of osteoporosis Fosamax (alendronate) or Actonel (risedronate) – Take the medication first thing in the morning 30 min. before other medication, beverages, food and remain upright for 30-60min – Engage in wt.-bearing exercise – Assess Ca+ and phosphate levels for baseline and during therapy
  • 5. Evista (raloxifene) – Take as directed; bone pain should be reported – Engage in regular wt.-bearing exercise – Report leg pain (DVT) – May cause hot flashes or induce ovulation – Monitor wt. weekly; report wt. gain

Editor's Notes

  1. A Colles' fracture is a fracture of the distal radius in the forearm with dorsal (posterior) and radial displacement of the wrist and hand. The fracture is sometimes referred to as a "dinner fork" or "bayonet" deformity due to the shape of the resultant forearm. (KABALIGTARAN IS SMITH’S FRACTURE) Porous -
  2. Caltrate – Increase level of intracellular and extracellular calcium; plays a role in normal cardiac and renal function, respiration, coagulation and cell membrane and capillary permeability; release storage of neurotransmitter and hormones
  3. Fosamax -Inhibits resorption of bone inhibiting osteoclast activity; Class: Bone resorption inhibitors and Biphosphonates Calcitonin -Directly inhibits osteoclasts, thereby reducing bone loss and increasing BMD Decreases Ca+ by a direct on bone, kidney and GI tract. Promotes renal excretion of Ca+ ; Class: Hypocalcemic Agent Hormone
  4. Evista -Binds to estrogen receptors, producing estrogen-like effects on bone resulting in reduced resorption of bone and decreased bone turnover and Competes for estrogen-binding sites in the breast, reducing estrogen response; class: SERM Selective estrogen receptor modulators and Bone resorption inhibitor