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Dr Nitish Arora
MS(Ortho), DNB, Fellowship-ASAMI
Former Consultant at St. Stephen's Hospital,
New-Delhi
Former Senior Resident at AIIMS, New-Delhi
AO Trauma-Faculty
ASAMI- Faculty
Consultant Trauma, Limb Reconstruction,
Deformity Correction & Pediatric Orthopedic
Surgeon
Collagen- Tensile
strength-
prevention of
fracture
Hydroxyapatite-
stiffness-
deformation under
load
Bone health/Cartilage health=Muscle
health
Modifiable
Lack of physical
activity/obesity
Indequate peak bone
mass due to lack of
Vit D and calcium rich
foods
Smoking
Alcohol
High caffeine intake
High salt intake
Abuse of antaacids
Not modifiable
Female
Increasing age
Early menopause
Medications and
medical conditions
Genetic factors
OBESIT
Y
Modifiable
• Lack of physical
activity/obesity
• Indequate peak bone mass
due to lack of Vit D and
calcium rich foods
• Smoking
• Alcohol
• High caffeine intake
• High salt intake
• Abuse of antaacids
Not modifiable
Female
Increasing age
Early menopause
Medications and
medical conditions
Genetic factors
Bone loss-
after Peak Bone
mass
Male-0.3%/year
Female-0.5%/year
Post menopausal- 1-
2%/year
Peak Bone Mass
PEAK BONE MASS
ROLE OF
CALCIUM/
VIT D
Not modifiable
Female
Increasing age
Early menopause
Medications and medical
conditions
Genetic factors
Modifiable
• Lack of physical
activity/obesity
• Indequate peak bone mass
due to lack of Vit D and
calcium rich foods
• Smoking
• Alcohol
• High caffeine intake
• High salt intake
• Abuse of antaacids
 Alcohol- daily intake of 3 or more units of alcohol increases the
risk of fracture.
 Osteoporosis/fracture- against consuming more than 7
drinks/week, 1 drink being equivalent to 120 mL of wine, 30 mL of
liquor, or 260 mL of beer
 Oral glucocorticoids ≥5 mg/d of prednisone for >3 months (ever)
 Abuse of antacids or some other medication(anticovulsant)
increases the risk of osteoporosis and fracture
 Patients should be advised to limit their caffeine intake to less
than 1 to 2 servings (8 to 12 ounces in each serving) of
caffeinated drinks per day.
MANAGEMENT
 Exercise
 A regular weight-bearing
exercise regimen (for example,
walking 30–40 min per session)
along with back and posture
exercises for a few minutes on
most days of the week should
be advocated throughout life.
 Cells have mechanoreceptors-
promotes osteogenic
precursors(bone forming)
 Dynamic(not simply static loads) + high intensity + Novel
exercises
Osteogenic effect
 Effect must be large enough and repeated to be clinically
relevant, and the gains must be maintained throughout the
life span to prevent fracture
 Exercise effects must be site specific
VITAMIN D
 Sunlight, salmon, codliveroil, egg yolk, sundried mushrooms
or vitamin D fortified foods
 Less than 1 year- 400 i.u/day of vit D
 1- 12 years-800 i.u/day of Vit D
 >12years-1000-1200 i.u/day
 Pregnancy-1000-4000 i.u day
 Elderly- 2000 i.u/day
 Diagnosed Rickets/osteoporosis/osteoporosis
Rickets-children- 3-6 lac I.u bolus divided in 6-8
weeks then maintainence dose
Osteoporosis/osteomalacia- 6 lacs i.u divided in
10 weeks then maintainence dose for a year.
CALCIUM
 milk, cheese and other dairy foods
 green leafy vegetables, such as broccoli, cabbage and
okra, but not spinach
 soya beans/Ragi
 tofu
 plant-based drinks (such as soya drink) with added
calcium
 nuts
 bread and anything made with fortified flour
 fish where you eat the bones, such as sardines and
pilchards
CALCIUM SUPPLEMENTS
 <1 year-200 mg of elemental calcium
 1-8 year-500 mg of elemental calcium
 8-19 years-1200 mg elemental calcium
 19-60 years-1000 mg of elemental calcium
 >60 years/pregnant/lactating-1200 mg of elemental calcium
OSTEOPORO
SIS
Definition
Silent disease-until
complicated by fracture
or pain
Fractures occur even
with minor fall
MANAGEMENT
In women age 65 and older and
men age 70 and older, recommend
BMD testing.
Recommend BMD testing to those
who have suffered a fracture, to
determine degree of disease
severity.
Initiate treatment in those with hip or
vertebral (clinical or morphometric)
fractures
Early management of fracture can
bring the patient to its near original
life style.
ANTIRESORBTIVE/ANABOLIC
MEDICATION
 With Diagnosed osteoporosis on BMD/DEXA scan
 With already sustained osteoporotic fractures
 Along with calcium and Vit D supplements
 To be started in consultation with a physician and to stopped
whenever asked
 Antiresorbtive-Alendronate/Zolendronic acid/
Ibandronate/Risedronate/Calcitonin
 Anabolic-Teriparatide
FRACTURE PREVENTION
CONSISTS OF BONE
HEALTH AND PREVENTION
OF FALLS
OSTEOARTHRITIS
MANAGEMENT
 W e i g h t
l o s s / c o n t r o l
 E x e r c i s e s
 NSAID’s
 Calcium/Vit D
 Braces
 Intraarticular injections
WHO NEEDS SURGERY ????
 You have pain in your knees
 You cannot stand for more than half an hour
 You cannot walk for more than half a kilometer
 You have to take pain killers more than 2 tabs/week
 Failure of all conservative methods of management
Total knee
replacement
High Tibial osteotomy
Unicondylar Knee
replacement
Questions???

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bone.pptx

  • 1. Dr Nitish Arora MS(Ortho), DNB, Fellowship-ASAMI Former Consultant at St. Stephen's Hospital, New-Delhi Former Senior Resident at AIIMS, New-Delhi AO Trauma-Faculty ASAMI- Faculty Consultant Trauma, Limb Reconstruction, Deformity Correction & Pediatric Orthopedic Surgeon
  • 2.
  • 3.
  • 4.
  • 6.
  • 8. Modifiable Lack of physical activity/obesity Indequate peak bone mass due to lack of Vit D and calcium rich foods Smoking Alcohol High caffeine intake High salt intake Abuse of antaacids Not modifiable Female Increasing age Early menopause Medications and medical conditions Genetic factors
  • 10. Modifiable • Lack of physical activity/obesity • Indequate peak bone mass due to lack of Vit D and calcium rich foods • Smoking • Alcohol • High caffeine intake • High salt intake • Abuse of antaacids Not modifiable Female Increasing age Early menopause Medications and medical conditions Genetic factors
  • 11. Bone loss- after Peak Bone mass Male-0.3%/year Female-0.5%/year Post menopausal- 1- 2%/year Peak Bone Mass
  • 14. Not modifiable Female Increasing age Early menopause Medications and medical conditions Genetic factors Modifiable • Lack of physical activity/obesity • Indequate peak bone mass due to lack of Vit D and calcium rich foods • Smoking • Alcohol • High caffeine intake • High salt intake • Abuse of antaacids
  • 15.  Alcohol- daily intake of 3 or more units of alcohol increases the risk of fracture.  Osteoporosis/fracture- against consuming more than 7 drinks/week, 1 drink being equivalent to 120 mL of wine, 30 mL of liquor, or 260 mL of beer  Oral glucocorticoids ≥5 mg/d of prednisone for >3 months (ever)  Abuse of antacids or some other medication(anticovulsant) increases the risk of osteoporosis and fracture  Patients should be advised to limit their caffeine intake to less than 1 to 2 servings (8 to 12 ounces in each serving) of caffeinated drinks per day.
  • 16. MANAGEMENT  Exercise  A regular weight-bearing exercise regimen (for example, walking 30–40 min per session) along with back and posture exercises for a few minutes on most days of the week should be advocated throughout life.  Cells have mechanoreceptors- promotes osteogenic precursors(bone forming)
  • 17.  Dynamic(not simply static loads) + high intensity + Novel exercises Osteogenic effect  Effect must be large enough and repeated to be clinically relevant, and the gains must be maintained throughout the life span to prevent fracture  Exercise effects must be site specific
  • 18. VITAMIN D  Sunlight, salmon, codliveroil, egg yolk, sundried mushrooms or vitamin D fortified foods  Less than 1 year- 400 i.u/day of vit D  1- 12 years-800 i.u/day of Vit D  >12years-1000-1200 i.u/day  Pregnancy-1000-4000 i.u day  Elderly- 2000 i.u/day  Diagnosed Rickets/osteoporosis/osteoporosis Rickets-children- 3-6 lac I.u bolus divided in 6-8 weeks then maintainence dose Osteoporosis/osteomalacia- 6 lacs i.u divided in 10 weeks then maintainence dose for a year.
  • 19. CALCIUM  milk, cheese and other dairy foods  green leafy vegetables, such as broccoli, cabbage and okra, but not spinach  soya beans/Ragi  tofu  plant-based drinks (such as soya drink) with added calcium  nuts  bread and anything made with fortified flour  fish where you eat the bones, such as sardines and pilchards
  • 20. CALCIUM SUPPLEMENTS  <1 year-200 mg of elemental calcium  1-8 year-500 mg of elemental calcium  8-19 years-1200 mg elemental calcium  19-60 years-1000 mg of elemental calcium  >60 years/pregnant/lactating-1200 mg of elemental calcium
  • 22. Silent disease-until complicated by fracture or pain Fractures occur even with minor fall
  • 23.
  • 25. In women age 65 and older and men age 70 and older, recommend BMD testing. Recommend BMD testing to those who have suffered a fracture, to determine degree of disease severity.
  • 26. Initiate treatment in those with hip or vertebral (clinical or morphometric) fractures Early management of fracture can bring the patient to its near original life style.
  • 27. ANTIRESORBTIVE/ANABOLIC MEDICATION  With Diagnosed osteoporosis on BMD/DEXA scan  With already sustained osteoporotic fractures  Along with calcium and Vit D supplements  To be started in consultation with a physician and to stopped whenever asked  Antiresorbtive-Alendronate/Zolendronic acid/ Ibandronate/Risedronate/Calcitonin  Anabolic-Teriparatide
  • 28. FRACTURE PREVENTION CONSISTS OF BONE HEALTH AND PREVENTION OF FALLS
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 36.
  • 37.
  • 38. MANAGEMENT  W e i g h t l o s s / c o n t r o l  E x e r c i s e s  NSAID’s  Calcium/Vit D  Braces  Intraarticular injections
  • 39.
  • 40. WHO NEEDS SURGERY ????  You have pain in your knees  You cannot stand for more than half an hour  You cannot walk for more than half a kilometer  You have to take pain killers more than 2 tabs/week  Failure of all conservative methods of management
  • 41.
  • 42. Total knee replacement High Tibial osteotomy Unicondylar Knee replacement