NUTRITIONAL GENOMICS.pptx
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Nutrigenomics studies how food and nutrients affect gene expression and determines individual nutritional needs based on genetics. It shows how substances in food directly or indirectly impact the human genome and gene expression. Certain diets can increase risk of diseases for some individuals based on their genes. Nutrigenomics aims to develop individualized nutrition interventions for prevention and treatment of chronic diseases based on a person's genetics and nutritional status.
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Nutrigenomics
the new emerging field of science that is nutrigenomics can deal with the issues of health and improve out health with the simple tools by understanding the risk and the baic genome of a person
Nutrigenomics
Nutrigenomics attempts to study how nutrition influences gene expression and metabolic pathways. It examines the dietary signatures - patterns of gene, protein, and metabolite expression - produced in cells and tissues in response to specific nutrients. Nutrigenomics seeks to understand how these signatures impact homeostasis and may help identify early biomarkers for conditions like insulin resistance. It takes a holistic approach using omics technologies like transcriptomics, proteomics, and metabolomics. Nutrigenomics also examines how genetics and environment interact to influence nutritional needs and responses.
Nutrigenomics
This document discusses nutrigenomics, which examines how diet interacts with an individual's genes and health. It describes how macronutrients and micronutrients can influence gene expression and molecular pathways related to energy homeostasis, nutrient absorption, cell proliferation, growth, immunity and normal body function. Specific examples are given of how fatty acids and glucose impact liver and adipose gene expression related to metabolism. The document also outlines techniques used in nutrigenomics research like RT-PCR, microarrays, and reporter systems that allow analysis of gene expression and regulation in response to dietary components.
Nutragenomics 2
This document discusses nutrigenomics, which is the study of how genes are affected by nutrients and dietary components. It covers how individual genetic variations influence nutrient metabolism and disease risk, with the goal of developing personalized diets. Key applications of nutrigenomics discussed include cardiovascular disease, bone health, diabetes, Alzheimer's, and cancer. Advances in high-throughput omics technologies and bioinformatics are enabling more comprehensive analysis of gene-diet interactions.
Nutritional Genomics
Nutritional genomics is the study of how genes interact with environmental factors like diet. It seeks to identify genes that influence disease risk and how bioactive foods can modify these genes to prevent or treat diseases. Research uses DNA microarrays to identify active and inactive genes in response to conditions. Small DNA variations called SNPs can increase disease risk when combined with environmental exposures like diet. Disease is influenced by multiple gene-environment interactions through the epigenome, which regulates genes in response to signals like dietary phytochemicals and nutrients. While adults can temporarily influence their epigenome through diet, most changes occur during development. Genetic testing can provide personalized nutrition advice but also raises ethical issues. Unethical companies falsely claim to provide personalized
Nutrigenomics
Nutrigenomics is the science that examines the response of individuals to food compounds using post-genomic and related technologies (e.g. genomics, transcriptomics, proteomics, metabol/nomic etc.). The long-term aim of nutrigenomics is to understand how the whole body responds to real foods using an integrated approach termed 'systems biology'. The huge advantage in this approach is that the studies can examine people (i.e. populations, sub-populations - based on genes or disease - and individuals), food, life-stage and life-style without preconceived ideas.
Personalized Nutrition
Personalized nutrition takes into account many individual factors like genetics, metabolism, microbiome, lifestyle and more to determine the optimal diet for health and well-being. It aims to manage and prevent chronic diseases through personalized sciences, guidance, and education. A personalized nutrition care model assesses individual data through tests and screens, interprets the results, designs targeted interventions like dietary changes, and monitors outcomes. Nutritional genomics and epigenetics research how genes and environment interact to influence health and disease, helping personalized nutrition better address individual needs.
Nutrigenomics
Nutrigenomics is the study of how nutrients and other food components interact with an individual's genome to affect gene expression. It examines how diet influences cellular processes and looks at individual variability in responses to foods based on genetic makeup. The main concepts are that specific diets can modulate health and disease by impacting gene expression, genetic polymorphisms influence disease risk and diet response, and personalized diets may help reduce risk for genetically predisposed individuals. Key applications of nutrigenomics include understanding how diet relates to obesity, type 2 diabetes, cardiovascular disease, cancer, and other chronic health conditions by studying gene-diet interactions and genetic variations.
Recommended
Nutrigenomics
the new emerging field of science that is nutrigenomics can deal with the issues of health and improve out health with the simple tools by understanding the risk and the baic genome of a person
Nutrigenomics
Nutrigenomics attempts to study how nutrition influences gene expression and metabolic pathways. It examines the dietary signatures - patterns of gene, protein, and metabolite expression - produced in cells and tissues in response to specific nutrients. Nutrigenomics seeks to understand how these signatures impact homeostasis and may help identify early biomarkers for conditions like insulin resistance. It takes a holistic approach using omics technologies like transcriptomics, proteomics, and metabolomics. Nutrigenomics also examines how genetics and environment interact to influence nutritional needs and responses.
Nutrigenomics
This document discusses nutrigenomics, which examines how diet interacts with an individual's genes and health. It describes how macronutrients and micronutrients can influence gene expression and molecular pathways related to energy homeostasis, nutrient absorption, cell proliferation, growth, immunity and normal body function. Specific examples are given of how fatty acids and glucose impact liver and adipose gene expression related to metabolism. The document also outlines techniques used in nutrigenomics research like RT-PCR, microarrays, and reporter systems that allow analysis of gene expression and regulation in response to dietary components.
Nutragenomics 2
This document discusses nutrigenomics, which is the study of how genes are affected by nutrients and dietary components. It covers how individual genetic variations influence nutrient metabolism and disease risk, with the goal of developing personalized diets. Key applications of nutrigenomics discussed include cardiovascular disease, bone health, diabetes, Alzheimer's, and cancer. Advances in high-throughput omics technologies and bioinformatics are enabling more comprehensive analysis of gene-diet interactions.
Nutritional Genomics
Nutritional genomics is the study of how genes interact with environmental factors like diet. It seeks to identify genes that influence disease risk and how bioactive foods can modify these genes to prevent or treat diseases. Research uses DNA microarrays to identify active and inactive genes in response to conditions. Small DNA variations called SNPs can increase disease risk when combined with environmental exposures like diet. Disease is influenced by multiple gene-environment interactions through the epigenome, which regulates genes in response to signals like dietary phytochemicals and nutrients. While adults can temporarily influence their epigenome through diet, most changes occur during development. Genetic testing can provide personalized nutrition advice but also raises ethical issues. Unethical companies falsely claim to provide personalized
Nutrigenomics
Nutrigenomics is the science that examines the response of individuals to food compounds using post-genomic and related technologies (e.g. genomics, transcriptomics, proteomics, metabol/nomic etc.). The long-term aim of nutrigenomics is to understand how the whole body responds to real foods using an integrated approach termed 'systems biology'. The huge advantage in this approach is that the studies can examine people (i.e. populations, sub-populations - based on genes or disease - and individuals), food, life-stage and life-style without preconceived ideas.
Personalized Nutrition
Personalized nutrition takes into account many individual factors like genetics, metabolism, microbiome, lifestyle and more to determine the optimal diet for health and well-being. It aims to manage and prevent chronic diseases through personalized sciences, guidance, and education. A personalized nutrition care model assesses individual data through tests and screens, interprets the results, designs targeted interventions like dietary changes, and monitors outcomes. Nutritional genomics and epigenetics research how genes and environment interact to influence health and disease, helping personalized nutrition better address individual needs.
Nutrigenomics
Nutrigenomics is the study of how nutrients and other food components interact with an individual's genome to affect gene expression. It examines how diet influences cellular processes and looks at individual variability in responses to foods based on genetic makeup. The main concepts are that specific diets can modulate health and disease by impacting gene expression, genetic polymorphisms influence disease risk and diet response, and personalized diets may help reduce risk for genetically predisposed individuals. Key applications of nutrigenomics include understanding how diet relates to obesity, type 2 diabetes, cardiovascular disease, cancer, and other chronic health conditions by studying gene-diet interactions and genetic variations.
Nutrigenomics
Nutrigenomics is the study of how nutrients and foods affect gene expression. It examines the interactions between an individual's genetics, diet, and health. The summary discusses three key areas:
1. Nutrigenomics research focuses on preventing chronic diseases like cancer, cardiovascular disease, and obesity by deactivating disease signaling pathways through nutrient supplements.
2. Specific nutrients can prevent these diseases. For example, polyunsaturated fatty acids can prevent cancer by regulating genes involved in cell growth, inflammation, and proliferation.
3. Personalized nutrition is an outcome of nutrigenomics and can be used to promote health through prevention and treatment of diseases, weight control, and immunity improvement.
Nutrigenomics
This document discusses nutrigenomics, which is defined as the study of how foods and their constituents affect gene expression. It provides definitions of nutrigenomics and related terms like nutrigenetics, epigenetics, and single nucleotide polymorphisms (SNPs). The document also examines how nutrigenomics research can provide insights into gene-diet interactions and their relationships to diseases like cancer, cardiovascular disease, obesity, and type 2 diabetes. Finally, it discusses some advantages and disadvantages of nutrigenomics as well as future directions for this area of research.
Neutrigenomics
Nutrigenomics is the study of how genetic variation affects the interaction between diet and health, with the goal of improving health through tailored diets and lifestyles. It analyzes how foods and their components influence genes, while nutrigenetics focuses on genetic variants that result in different responses to nutrients. Advances in molecular biology now enable analyzing these interactions through transcriptomics, proteomics and metabolomics. While nutrigenomic testing promises personalized nutrition, concerns remain regarding its effectiveness and implications.
Nutrigenomics
Nutrigenomics is the application of genomics to nutritional research to understand how foods and dietary components influence gene expression. It studies the interactions between nutrition, genes, and health on a genome-wide scale. The goals of nutrigenomics are to identify dietary signals, understand how they interact with genes and signaling pathways, characterize target genes, and use this information to develop personalized diets that can help prevent diseases. Future applications include using nutrigenomics approaches to better understand polygenic diseases and create customized diets based on an individual's genetic profile.
Nutrigenomics
What is nutrigenomics ,introduction to genomic,introduction to nutrigenomics, examples ,1)folate2) pku 3)lactose intolersnce
2)antiaging
Diet disease interaction ,advantages of nutrigenomics ,disadvantages of nutrigenomics
why need of nutrigenomic,what are the uses of nutrigenomics,
nutrigenomics.ppt
This document provides an introduction to nutrigenomics and its applications. It discusses how nutrigenomics is the study of how dietary components interact with genes and alter gene expression. There are different types of food-gene interactions, including direct interactions where nutrients directly bind to receptors and regulate genes, and epigenetic interactions where nutrients can alter DNA structure and chronically change gene expression. Nutrigenomics helps understand how an individual's genetic makeup can influence their susceptibility to diet-related diseases and how personalized diets based on genetics can be used for disease prevention and treatment. The document outlines several examples of how nutrigenomics provides insights into cardiovascular, cancer, obesity and hypertension by studying genetic factors and their interaction with diet.
Intro into Nutrigenomics & molecular nutrition research
My recent introduction talk for the Nutrigenomics Masterclass 2011 in Wageningen (The Netherlands):
How to use Nutrigenomics & molecular nutrition? From challenges to solutions
Nutrigenetics: Possibilities and limitations in the treatment of overweight...
1) The document discusses nutrigenetics and its potential role in treating overweight and obesity. It outlines several candidate genes associated with obesity like FTO and genes involved in the leptin/melanocortin pathway.
2) Large genome-wide studies have identified hundreds of genetic loci associated with obesity but genetics only accounts for a small percentage of BMI variation. Environmental factors are still the major driver of obesity.
3) While leptin therapy reduced weight in leptin-deficient individuals, it did not significantly reduce weight in common obesity cases. Further research is still needed to determine nutrigenetic approaches for obesity treatment and prevention.
Ecological factors in nutrient assessment
This document discusses factors that should be assessed when evaluating ecology, including a food balance sheet, socio-economic factors, health and educational services, and conditioning influences. A food balance sheet indirectly assesses food consumption by relating food supplies to population, providing general consumption patterns for the country. Socio-economic groups vary in factors like family size, occupation, income, and customs that influence food consumption. Health services like primary care, feeding programs, and immunization should also be considered, as well as conditioning influences like infections that can precipitate malnutrition.
Nutrigenomics: An emerging science in Nutrition
This document discusses nutrigenomics, which is the study of how nutrients and bioactive compounds in food affect gene expression. It provides examples of how different nutrients like carbohydrates, fat, protein, minerals and vitamins can regulate gene expression. Key techniques in nutrigenomics like transcriptomics, proteomics and metabolomics are also summarized. The document outlines several potential applications of nutrigenomics like developing customized feeds tailored to an animal's genotype, selecting nutrients to fine-tune gene activity, and gaining insights into performance and disease.
The Impact of Nutrition and Environmental Epigenetics
1. Nutrition and environmental exposures can impact human health and disease through epigenetic mechanisms. Maternal diet and pollution exposure during pregnancy can result in epigenetic changes in offspring that affect disease risk.
2. Endocrine disrupting chemicals and other pollutants are epigenetic toxins that can cause global and gene-specific changes to DNA methylation and histone modifications, interfering with normal development and increasing cancer risk.
3. Dietary factors like nutrients from the Mediterranean diet have been associated with reduced disease risk and positive neurodevelopmental outcomes in children through epigenetic effects.
Nutrition transition-presentation-2018-final
The document discusses the nutrition transition, defined as the shift in dietary consumption and energy expenditure that accompanies economic, demographic, and epidemiological changes. It outlines the 5 stages of the nutrition transition: 1) collecting food, 2) famine, 3) receding famine, 4) nutrition-related non-communicable diseases, and 5) behavioral change. Urbanization is contributing to nutrition transitions in developing countries as diets shift toward more processed foods and a more sedentary lifestyle. This nutrition transition is creating a double burden of disease and negatively impacting health systems in developing nations.
NUTRITIONAL GENOMICS
This document provides an overview of nutritional genomics, which combines molecular biology, genetics, and nutrition. Nutritional genomics examines how diet, nutrients, and food components interact with an individual's genetic makeup to influence health and disease. It discusses key concepts like nutrigenomics, which focuses on how nutrients affect genes and metabolic processes, and nutrigenetics, which examines how genetic variations influence interactions between diet and health. The document also outlines some tools and techniques used in nutritional genomics, such as analyzing single nucleotide polymorphisms to understand individual responses to nutrients.
Nutrigenomics
Nutrigenomics is the study of how nutrients and other food components influence gene expression and health. It considers how an individual's genetic makeup influences their response to different diets. The main concepts are that specific diets can modulate health by influencing gene expression, genetic factors affect disease risk, and personalized diets based on genetics may lower risk. Improper diets are linked to disease risk, while certain foods and chemicals can alter gene expression or genome structure. An individual's response depends on their genetic profile, like single nucleotide polymorphisms. Nutrigenomics studies seek to develop personalized diets to prevent diseases based on genetic risk factors.
Maternal Nutrition and Epigenetics
This document discusses how maternal nutrition can influence fetal epigenetics. It begins by introducing epigenetic mechanisms like DNA methylation and histone modification. Environmental factors during pregnancy like nutrition, pollutants, and microbiota can induce epigenetic changes impacting fetal development and long term health. Specific nutrients that are important for epigenetics include folate, choline, vitamin D, and long chain fatty acids. Maternal undernutrition and overnutrition can both induce epigenetic changes linked to diseases. Breastfeeding promotes a healthy microbiota and epigenetic patterns that provide long term benefits to offspring.
Nutrigenomics
Nutrigenomics is the study of how foods and their components influence gene expression. It uses molecular tools to understand individual responses to different diets. Key "omics" sciences used in nutrigenomics include genomics, transcriptomics, proteomics, metabolomics, and epigenomics. Nutrigenomics research monitors changes in an organism's transcriptome, proteome, and metabolome in response to diet. Single nucleotide polymorphisms (SNPs) are important genetic variations studied in nutrigenomics as they can influence nutrient absorption, metabolism, and biological effects. Nutrigenomics seeks to understand how genetic predispositions influence disease development and can provide personalized dietary recommendations. Improving nutrigenomics awareness can help
Effect of Nutritional Factors on Regulation of Gene Expression
Nutritional factors from fish feed can modify the expression of specific genes in fish related to metabolic pathways. High levels of proteins, carbohydrates, lipids, vitamins and minerals upregulate genes involved in digestion, growth, and metabolism of the corresponding macronutrients. For example, a high-carbohydrate diet increases expression of genes for starch-digesting enzymes, while essential amino acids increase growth factor genes. Nutrigenomics research uses techniques like microarray analysis and reverse transcription PCR to study how nutrients regulate whole networks of genes and cellular processes in fish. Understanding these gene expression changes can help design optimized fish feeds that improve production and welfare.
the role of diet & supplements in cancer
This document discusses the role of nutrition in preventing cancer. It states that up to 80% of cancers may be preventable through lifestyle changes like diet and smoking. Diet is thought to account for 30% of cancer deaths. Studies show that migration from Asia to Western countries increases cancer rates, demonstrating the importance of lifestyle. The document then examines the role of several foods and nutrients in preventing colorectal cancer, including calcium, vitamin D, fiber, B vitamins, antioxidants, and selenium. It provides mechanisms and evidence from studies on how higher intake of these nutrients may lower colorectal cancer risk.
Genetic Factors
Genetics play a significant role in obesity, accounting for 30-40% of cases. Twin studies show genetics have a strong influence on body mass index (BMI) with monozygotic twins having more similar BMIs than dizygotic twins. While single-gene defects cause rare cases of severe obesity, most common obesity is influenced by dozens to hundreds of genes interacting with environmental and behavioral factors. The roles of these genes are still being uncovered, but genetics are not destiny as lifestyle choices can counteract genetic effects, and not all carriers of obesity genes become overweight.
Nutritional regulation of gene expression
Nutrigenomics is the study of how nutrients and bioactive food components influence gene expression and how genetic variations affect individual responses to specific foods or nutrients. It seeks to understand how diet influences health and disease risk based on a person's genetic makeup. Key concepts include that specific diets can modulate health by influencing gene expression, genetic polymorphisms affect disease risk and response to diet, and personalized diets based on genetics may lower disease risk. Nutrigenomics research is providing insights into relationships between nutrition, genes, and chronic diseases like obesity, cardiovascular disease, and cancer.
Sajjad.moradi
This document discusses nutrition and genomics. It begins with an introduction to nutrigenomics, which examines how foods affect genetic expression and how an individual's genetics influence nutrient metabolism and response. It then covers nutrigenetics, nutrigenomics, and nutritional epigenomics, and how bioactive food components can influence genetic and epigenetic events. Problems in the field include food variability and the complex relationship between genes and disease. However, future potential includes developing personalized dietary interventions to prevent disease and validating product claims.
15
This document discusses nutrigenomics and nutrigenetics, which are two related but distinct fields that examine the relationship between genetics and nutrition. Nutrigenomics looks at how foods and nutrients influence gene expression, while nutrigenetics focuses on how genetic variations impact an individual's response to specific foods and nutrients. The document provides examples of how knowledge in these fields can help identify personalized diets and nutritional interventions tailored to one's genetic profile that may help prevent or treat chronic diseases like obesity, cardiovascular disease, and cancer. It also discusses some specific genetic disorders like lactose intolerance and phenylketonuria where restricting certain foods can benefit affected individuals.
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Nutrigenomics
Nutrigenomics is the study of how nutrients and foods affect gene expression. It examines the interactions between an individual's genetics, diet, and health. The summary discusses three key areas:
1. Nutrigenomics research focuses on preventing chronic diseases like cancer, cardiovascular disease, and obesity by deactivating disease signaling pathways through nutrient supplements.
2. Specific nutrients can prevent these diseases. For example, polyunsaturated fatty acids can prevent cancer by regulating genes involved in cell growth, inflammation, and proliferation.
3. Personalized nutrition is an outcome of nutrigenomics and can be used to promote health through prevention and treatment of diseases, weight control, and immunity improvement.
Nutrigenomics
This document discusses nutrigenomics, which is defined as the study of how foods and their constituents affect gene expression. It provides definitions of nutrigenomics and related terms like nutrigenetics, epigenetics, and single nucleotide polymorphisms (SNPs). The document also examines how nutrigenomics research can provide insights into gene-diet interactions and their relationships to diseases like cancer, cardiovascular disease, obesity, and type 2 diabetes. Finally, it discusses some advantages and disadvantages of nutrigenomics as well as future directions for this area of research.
Neutrigenomics
Nutrigenomics is the study of how genetic variation affects the interaction between diet and health, with the goal of improving health through tailored diets and lifestyles. It analyzes how foods and their components influence genes, while nutrigenetics focuses on genetic variants that result in different responses to nutrients. Advances in molecular biology now enable analyzing these interactions through transcriptomics, proteomics and metabolomics. While nutrigenomic testing promises personalized nutrition, concerns remain regarding its effectiveness and implications.
Nutrigenomics
Nutrigenomics is the application of genomics to nutritional research to understand how foods and dietary components influence gene expression. It studies the interactions between nutrition, genes, and health on a genome-wide scale. The goals of nutrigenomics are to identify dietary signals, understand how they interact with genes and signaling pathways, characterize target genes, and use this information to develop personalized diets that can help prevent diseases. Future applications include using nutrigenomics approaches to better understand polygenic diseases and create customized diets based on an individual's genetic profile.
Nutrigenomics
What is nutrigenomics ,introduction to genomic,introduction to nutrigenomics, examples ,1)folate2) pku 3)lactose intolersnce
2)antiaging
Diet disease interaction ,advantages of nutrigenomics ,disadvantages of nutrigenomics
why need of nutrigenomic,what are the uses of nutrigenomics,
nutrigenomics.ppt
This document provides an introduction to nutrigenomics and its applications. It discusses how nutrigenomics is the study of how dietary components interact with genes and alter gene expression. There are different types of food-gene interactions, including direct interactions where nutrients directly bind to receptors and regulate genes, and epigenetic interactions where nutrients can alter DNA structure and chronically change gene expression. Nutrigenomics helps understand how an individual's genetic makeup can influence their susceptibility to diet-related diseases and how personalized diets based on genetics can be used for disease prevention and treatment. The document outlines several examples of how nutrigenomics provides insights into cardiovascular, cancer, obesity and hypertension by studying genetic factors and their interaction with diet.
Intro into Nutrigenomics & molecular nutrition research
My recent introduction talk for the Nutrigenomics Masterclass 2011 in Wageningen (The Netherlands):
How to use Nutrigenomics & molecular nutrition? From challenges to solutions
Nutrigenetics: Possibilities and limitations in the treatment of overweight...
1) The document discusses nutrigenetics and its potential role in treating overweight and obesity. It outlines several candidate genes associated with obesity like FTO and genes involved in the leptin/melanocortin pathway.
2) Large genome-wide studies have identified hundreds of genetic loci associated with obesity but genetics only accounts for a small percentage of BMI variation. Environmental factors are still the major driver of obesity.
3) While leptin therapy reduced weight in leptin-deficient individuals, it did not significantly reduce weight in common obesity cases. Further research is still needed to determine nutrigenetic approaches for obesity treatment and prevention.
Ecological factors in nutrient assessment
This document discusses factors that should be assessed when evaluating ecology, including a food balance sheet, socio-economic factors, health and educational services, and conditioning influences. A food balance sheet indirectly assesses food consumption by relating food supplies to population, providing general consumption patterns for the country. Socio-economic groups vary in factors like family size, occupation, income, and customs that influence food consumption. Health services like primary care, feeding programs, and immunization should also be considered, as well as conditioning influences like infections that can precipitate malnutrition.
Nutrigenomics: An emerging science in Nutrition
This document discusses nutrigenomics, which is the study of how nutrients and bioactive compounds in food affect gene expression. It provides examples of how different nutrients like carbohydrates, fat, protein, minerals and vitamins can regulate gene expression. Key techniques in nutrigenomics like transcriptomics, proteomics and metabolomics are also summarized. The document outlines several potential applications of nutrigenomics like developing customized feeds tailored to an animal's genotype, selecting nutrients to fine-tune gene activity, and gaining insights into performance and disease.
The Impact of Nutrition and Environmental Epigenetics
1. Nutrition and environmental exposures can impact human health and disease through epigenetic mechanisms. Maternal diet and pollution exposure during pregnancy can result in epigenetic changes in offspring that affect disease risk.
2. Endocrine disrupting chemicals and other pollutants are epigenetic toxins that can cause global and gene-specific changes to DNA methylation and histone modifications, interfering with normal development and increasing cancer risk.
3. Dietary factors like nutrients from the Mediterranean diet have been associated with reduced disease risk and positive neurodevelopmental outcomes in children through epigenetic effects.
Nutrition transition-presentation-2018-final
The document discusses the nutrition transition, defined as the shift in dietary consumption and energy expenditure that accompanies economic, demographic, and epidemiological changes. It outlines the 5 stages of the nutrition transition: 1) collecting food, 2) famine, 3) receding famine, 4) nutrition-related non-communicable diseases, and 5) behavioral change. Urbanization is contributing to nutrition transitions in developing countries as diets shift toward more processed foods and a more sedentary lifestyle. This nutrition transition is creating a double burden of disease and negatively impacting health systems in developing nations.
NUTRITIONAL GENOMICS
This document provides an overview of nutritional genomics, which combines molecular biology, genetics, and nutrition. Nutritional genomics examines how diet, nutrients, and food components interact with an individual's genetic makeup to influence health and disease. It discusses key concepts like nutrigenomics, which focuses on how nutrients affect genes and metabolic processes, and nutrigenetics, which examines how genetic variations influence interactions between diet and health. The document also outlines some tools and techniques used in nutritional genomics, such as analyzing single nucleotide polymorphisms to understand individual responses to nutrients.
Nutrigenomics
Nutrigenomics is the study of how nutrients and other food components influence gene expression and health. It considers how an individual's genetic makeup influences their response to different diets. The main concepts are that specific diets can modulate health by influencing gene expression, genetic factors affect disease risk, and personalized diets based on genetics may lower risk. Improper diets are linked to disease risk, while certain foods and chemicals can alter gene expression or genome structure. An individual's response depends on their genetic profile, like single nucleotide polymorphisms. Nutrigenomics studies seek to develop personalized diets to prevent diseases based on genetic risk factors.
Maternal Nutrition and Epigenetics
This document discusses how maternal nutrition can influence fetal epigenetics. It begins by introducing epigenetic mechanisms like DNA methylation and histone modification. Environmental factors during pregnancy like nutrition, pollutants, and microbiota can induce epigenetic changes impacting fetal development and long term health. Specific nutrients that are important for epigenetics include folate, choline, vitamin D, and long chain fatty acids. Maternal undernutrition and overnutrition can both induce epigenetic changes linked to diseases. Breastfeeding promotes a healthy microbiota and epigenetic patterns that provide long term benefits to offspring.
Nutrigenomics
Nutrigenomics is the study of how foods and their components influence gene expression. It uses molecular tools to understand individual responses to different diets. Key "omics" sciences used in nutrigenomics include genomics, transcriptomics, proteomics, metabolomics, and epigenomics. Nutrigenomics research monitors changes in an organism's transcriptome, proteome, and metabolome in response to diet. Single nucleotide polymorphisms (SNPs) are important genetic variations studied in nutrigenomics as they can influence nutrient absorption, metabolism, and biological effects. Nutrigenomics seeks to understand how genetic predispositions influence disease development and can provide personalized dietary recommendations. Improving nutrigenomics awareness can help
Effect of Nutritional Factors on Regulation of Gene Expression
Nutritional factors from fish feed can modify the expression of specific genes in fish related to metabolic pathways. High levels of proteins, carbohydrates, lipids, vitamins and minerals upregulate genes involved in digestion, growth, and metabolism of the corresponding macronutrients. For example, a high-carbohydrate diet increases expression of genes for starch-digesting enzymes, while essential amino acids increase growth factor genes. Nutrigenomics research uses techniques like microarray analysis and reverse transcription PCR to study how nutrients regulate whole networks of genes and cellular processes in fish. Understanding these gene expression changes can help design optimized fish feeds that improve production and welfare.
the role of diet & supplements in cancer
This document discusses the role of nutrition in preventing cancer. It states that up to 80% of cancers may be preventable through lifestyle changes like diet and smoking. Diet is thought to account for 30% of cancer deaths. Studies show that migration from Asia to Western countries increases cancer rates, demonstrating the importance of lifestyle. The document then examines the role of several foods and nutrients in preventing colorectal cancer, including calcium, vitamin D, fiber, B vitamins, antioxidants, and selenium. It provides mechanisms and evidence from studies on how higher intake of these nutrients may lower colorectal cancer risk.
Genetic Factors
Genetics play a significant role in obesity, accounting for 30-40% of cases. Twin studies show genetics have a strong influence on body mass index (BMI) with monozygotic twins having more similar BMIs than dizygotic twins. While single-gene defects cause rare cases of severe obesity, most common obesity is influenced by dozens to hundreds of genes interacting with environmental and behavioral factors. The roles of these genes are still being uncovered, but genetics are not destiny as lifestyle choices can counteract genetic effects, and not all carriers of obesity genes become overweight.
Nutritional regulation of gene expression
Nutrigenomics is the study of how nutrients and bioactive food components influence gene expression and how genetic variations affect individual responses to specific foods or nutrients. It seeks to understand how diet influences health and disease risk based on a person's genetic makeup. Key concepts include that specific diets can modulate health by influencing gene expression, genetic polymorphisms affect disease risk and response to diet, and personalized diets based on genetics may lower disease risk. Nutrigenomics research is providing insights into relationships between nutrition, genes, and chronic diseases like obesity, cardiovascular disease, and cancer.
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Similar to NUTRITIONAL GENOMICS.pptx
Sajjad.moradi
This document discusses nutrition and genomics. It begins with an introduction to nutrigenomics, which examines how foods affect genetic expression and how an individual's genetics influence nutrient metabolism and response. It then covers nutrigenetics, nutrigenomics, and nutritional epigenomics, and how bioactive food components can influence genetic and epigenetic events. Problems in the field include food variability and the complex relationship between genes and disease. However, future potential includes developing personalized dietary interventions to prevent disease and validating product claims.
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This document discusses nutrigenomics and nutrigenetics, which are two related but distinct fields that examine the relationship between genetics and nutrition. Nutrigenomics looks at how foods and nutrients influence gene expression, while nutrigenetics focuses on how genetic variations impact an individual's response to specific foods and nutrients. The document provides examples of how knowledge in these fields can help identify personalized diets and nutritional interventions tailored to one's genetic profile that may help prevent or treat chronic diseases like obesity, cardiovascular disease, and cancer. It also discusses some specific genetic disorders like lactose intolerance and phenylketonuria where restricting certain foods can benefit affected individuals.
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Nutrigenomics
Nutrigenomics is the study of how nutrients and other food components influence gene expression. It seeks to understand how nutrition impacts homeostasis at the cellular and genetic levels. The main concepts are that specific diets can modulate health and disease by affecting gene expression, an individual's genetic makeup influences their response to diet and disease risk, and personalized diets based on genetics may lower risk. Nutrigenomics examines how nutrients directly or indirectly regulate genes and how genetic variations impact nutrient metabolism and disease. It studies relationships between diet, genes and chronic diseases like obesity, diabetes, cancer and cardiovascular disease.
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Nutrigenomics is the study of how foods and their components affect gene expression. It explores how an individual's genetic makeup influences their nutritional requirements and response to foods. Single nucleotide polymorphisms, which are small genetic differences between individuals, can change how one metabolizes and responds to diet, and influence disease risk patterns. Understanding nutrigenomics may help prevent diseases by developing personalized diets and promoting healthy lifestyle choices based on one's genetics.
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1. Nutrigenomics is the study of how nutrients and other food components influence gene expression and health. It seeks to understand how an individual's genetic makeup determines their response to different diets.
2. Specific dietary components can modulate the balance between health and disease by directly or indirectly impacting gene expression. An individual's genetic profile, including polymorphisms in nutrient-regulated genes, affects their risk of diseases.
3. Personalized diets tailored to one's genotype may help lower disease risk in genetically predisposed groups by accounting for how genetics influence the body's response to different nutrients.
Nutrigenomics
This presentation discusses nutrigenomics, which is the study of how genes interact with nutrition, especially in preventing and treating disease. Nutrigenomics is driven by new technological tools that provide a more complex understanding of how food components interact with biochemical networks. The presentation emphasizes the identification of novel biomarkers for inflammatory diseases and the role of the human microbiome. It also discusses nutrigenetics, nutrigenomics, and epigenetics in personalized nutrition approaches. Individual genetic profiles affect nutrient requirements and responses to diet and lifestyle interventions. Advances in genetic science are enabling more personalized nutrition solutions to emerging public health problems by reducing nutrition-related disease risk and prevalence through approaches like nutrigenomics, metabolomics, and functional food
Outline_2015_עתיד
This document discusses the field of nutrigenomics, which examines the relationship between genes, nutrition, and health. It notes that nutrigenomics can provide personalized nutrition advice by understanding how genetic variants affect an individual's response to different foods. The document also discusses how epigenetics and early life nutrition can influence gene expression and lifelong health, and how nutrigenomics may help address inconsistent responses to general dietary recommendations and help develop more individualized diets.
Nutrigenomics: The Genome food interface
This document provides an overview of nutrigenomics, including:
- The definition of nutrigenomics as studying the relationship between human genome, nutrition and health.
- How nutrients can interact with genes through direct interaction, epigenetic interactions, and genetic variations.
- Tools and databases used in nutrigenomics research like BioConductor and the Nutritional Phenotype database.
- Examples of how nutrigenomics research can inform plant breeding to develop crops with improved nutritional profiles through approaches like marker-assisted selection and genome editing.
Nutrigenomics: Perio-nutrition interrelationship
The study of how genes and gene products interact with dietary chemicals to alter phenotype and, conversely, how genes and their products metabolize nutrients is called nutritional genomics or “Nutrigenomics”.
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Our doctors are trained in conventional Western Medicine (from the UK) but also in lifestyle, precision and functional medicine. This looks deeply into diet, nutrition, exercise, sleep, stress, inflammation, genetics and chronic disease risk to optimise health with a holistic and patient-centred approach.
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What is Epigenetic Changes? Understanding Their Role in Health and Disease | ...
What is Epigenetic Changes? Understanding Their Role in Health and Disease | ...The Lifesciences Magazine
Epigenetic changes are garnering increasing attention in the field of genetics and medicine for their profound influence on gene expression and cellular function.Nutrigenomics
This document provides an overview of nutrigenomics. It begins with basic definitions and concepts in genetics and genomics such as the genome, chromosomes, genes, and the Human Genome Project. It then discusses how nutrigenomics studies the relationship between nutrition, genes, and health. Key aspects covered include nutrigenetics, which examines how genetics influence nutrient metabolism, and nutrigenomics, which looks at how nutrients affect gene expression. Examples are given of nutrigenetic factors like MTHFR polymorphisms and diseases like sickle cell anemia. Methods used in nutrigenomics and its applications in functional foods, personalized diets, and chronic diseases are summarized. The document concludes by discussing nutrigenomic
Nutrigenomics
Food intake and the environment are the two major factors that affect the health or illness of an individual. Studies in nutritional area have increased the understanding of how to maintain healthy groups of individuals that live in different dietary conditions. After the conclusion and assessment of the Human Genome Project (HGP), new insights about the influence of nutrients into people’s diet were postulated, which included, Some examples of this gene-nutrient interaction are their capacity on binding to the main transcription factors(Cahill et al.,2003). This binding enhances or interferes with the ability of transcription factors on interacting with elements that will pave to the binding control of RNA polymerase. Interactome also have a major role to play in nutrigenomics (Sreeremya, 2018)
NUTRIGENETICS AND PERSONALZIED NUTRITION DUBAI 2020.pptx
This document discusses personalized nutrition using nutrigenetics and nutrigenomics in clinical practice. It describes how genetic testing can be used to understand an individual's nutritional needs and disease risks based on their genetic variations and single nucleotide polymorphisms (SNPs). SNPs may help predict disease susceptibility, dietary requirements, and drug responses. Understanding a person's genomic background through genetic testing can help design personalized diets and supplement plans tailored to their individual genetics.
Preformulation studies of genetic aspects for drug development
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The Influence of Nutrition in Alzheimer's Disease: Neuroinflammation and the Microbiome vs. Transmissible Prion
Epigentics
Epigenetics is the study of heritable phenotypic changes that do not involve alterations to the DNA sequence. Epigenetic changes are influenced by factors like age, environment, lifestyle, and disease state, and can occur through DNA methylation, histone modification, and gene silencing. Epigenetic modifications can develop in different cell types and can be transmitted transgenerationally, potentially influencing traits and disease risk in offspring. Environmental exposures during development like a mother's pollution exposure or nutrition intake can impact epigenetic changes in her child with effects on traits and disease susceptibility.
04Personalized medicine.pptx
This document provides an introduction to personalized medicine and pharmacogenetics. It defines personalized medicine as using a person's genetic information to guide prevention, diagnosis, and treatment of disease. The key aspects are integrating a person's genes and proteins to understand how they will respond to specific treatments. Pharmacogenetics is the study of how genetic variations impact individual responses to drugs, with the goal of determining the right drug, dose, and treatment for each patient. Genome-wide association studies and candidate gene studies are approaches to identify genetic factors that influence drug responses and disease. The ultimate aim is to improve health outcomes by optimizing treatments based on a personalized understanding of an individual's genetics.
Similar to NUTRITIONAL GENOMICS.pptx (20)
What is Epigenetic Changes? Understanding Their Role in Health and Disease | ...
What is Epigenetic Changes? Understanding Their Role in Health and Disease | ...
NUTRIGENETICS AND PERSONALZIED NUTRITION DUBAI 2020.pptx
NUTRIGENETICS AND PERSONALZIED NUTRITION DUBAI 2020.pptx
Preformulation studies of genetic aspects for drug development
Preformulation studies of genetic aspects for drug development
NUTRITIONAL GENOMICS.pptx
- 2. Nutrigenomics is establishing the effect of ingested nutrients and other food components on gene expression. It is fusion of nutrition and genomics. It will also determine the individual nutritional requirements based on the genetic makeup of the person as well as the association between diet and chronic diseases
- 3. Substances contained in the food (micro-macro- nutrients)can directly or indirectly affect the human genome through changes in its structure and gene expression Under certain circumstances and in some individual that diet can be an important risk factor for the development of the number of diseases. Some gene regulated by active substances in the diet probably play a crucial role in the on set, incidence, progression and severity of the disease.
- 4. The degree to which diet influences the balance between health and disease may depend on individuals genetic makeup. Nutritional interventions is based on the knowledge of individuals nutritional status and needs as well as genotype(individualized nutrition)and can be used for prevention, mitigation or healing the chronic diseases.
- 5. DNA Gene regulation ,SNP’s,trancriptional control,histone interaction RNA Translational controlprocessing,stability, transport of mRNA Protein Post-translational modifications Receptor expression,Enzyme regulation,Singnal transduction ,transport regulation Metabolite All cellular mediators FOOD Nutrients& non-nutriens Diet,nutrition &Health
- 6. Direct interactions Nutrients , sometimes after interacting with receptors , behave as transcription factors that can bind to DNA and a cutely induce gene expression. Epigenetic interactions Nutrients can alter the structure of DNA so that gene expression is chronically altered. Gene variation Common genetic variation such as single nucleotide polymorphism(SNP)s can alter the expression or functionality of gene.
- 7. Cardiovascular diseases cardiovascular disease is a chronic disease that is related group of abnormal condition such as obesity hypertension and thrombosis. ApolipoproteinA-1 HDL is produced