Nutrigenomics is the study of how foods and their components influence gene expression. It uses molecular tools to understand individual responses to different diets. Key "omics" sciences used in nutrigenomics include genomics, transcriptomics, proteomics, metabolomics, and epigenomics. Nutrigenomics research monitors changes in an organism's transcriptome, proteome, and metabolome in response to diet. Single nucleotide polymorphisms (SNPs) are important genetic variations studied in nutrigenomics as they can influence nutrient absorption, metabolism, and biological effects. Nutrigenomics seeks to understand how genetic predispositions influence disease development and can provide personalized dietary recommendations. Improving nutrigenomics awareness can help

1. Nutrigenomics
DO THU THAO
ID student: 16110586
Meat and Muscle laboratory

2. Nutrigenomics - concept
What is the Nutrigenomics?
•Nutrigenomics is the study of
the effects of foods and food
constituents on gene
expression.
•Nutrigenomics is the area of
nutrition that uses molecular
tools to search, access, and
understand the several
responses obtained through a
certain diet applied between
individuals or population
groups confus
e

3. Nutrigenomics - concept
“Omics” sciences used in understanding the relationship between nutrition versus health versus disease
• After Genomics, other “Omic” Sciences appeared as revolutionary
tools, such as Proteomics, Metabolomics and Transcriptomics

4. Nutrigenomics - concept
• How Nutrigenomics is importance?
Estimated mortality from coronary heart
disease.
Source: Trehan 2006
Objective
•public awareness about the changing
lifestyle and food habits
•how nutrigenomics can contribute in
making life longer, healthier and better
•encourage more research in this field.

5. Nutrigenomics - applications
Nutrigenomics and “Omics” sciences

6. Nutrigenomics -
applications• Epigenomics can be defined as the study of the complete
set of epigenetic modifications in a cell or in a tissue at a
given time.
• The epigenetic studies the modification of DNA and proteins,
linking the DNA and histones, which may cause changes in
chromatin structure without changing the sequence of the
nucleotides
• Epigenetics is the
transmitted information
based on gene expression
as its changes begin slowly
but are progressive and
potentially reversible

7. Nutrigenomics - applications
Nutrigenomics research tools
: monitor the transcriptome,
proteome and metabolome.
•Transcriptomics
technologies are the
techniques used to study an
organism’s transcriptome,
the sum of all of its RNA
transcripts. (Example:
Microarrays, RNA-seq).
•The transcriptome is the set
of all RNA molecules in one
cell or a population of cells

8. Nutrigenomics - applications
• Proteomics is the large-scale study of proteomes studies
the complete set of proteins involved in the biological
processes of a certain species
• Proteomics can be classified :
Structural Proteomics
Functional Proteomics
Expression Proteomics
• proteomics techniques

9. Nutrigenomics - Nontransmissible
Chromic Diseases (NTCDs)
• What is relative between single-nucleotide polymorphism
(SNPs) ?
• Nutrigenomics has also been described by the influence of
SNPs with a nutrient's absorption, metabolism, elimination
or biological effects

10. Nutrigenomics -
Nontransmissible Chromic
Diseases (NTCDs)
Among different types of genetic variation between humans, SNPs are suggested to be
the most important marker for the study of nutrigenomics.

11. Nutrigenomics -
Nontransmissible Chromic
Diseases (NTCDs)
Obesity
•Multiple studies have found
association between SNPs
and obesity. One of the
most well known obesity
associating gene is the FTO
gene

12. Nutrigenomics - Nontransmissible
Chromic Diseases (NTCDs)
Type II Diabetes
•there are 65 SNPs
associated with the risk of
developing type II
Diabetes.
•patients who received a
positive result for the
presence of type II
Diabetes change their life
style, especially in their
food intake.

13. What aims of
nutrigenomics?
• Nutrigenomics seeks to understand the effect of different genetic
predispositions in the development of diseases found and measured in an
individual
quantified and personalized dietary recommendation can be given for

14. Nutrigenomics and awareness
• Addressing the
genetics and
nutritional genomics
knowledge gap will
help in eradicating
the social issues,
create more
awareness,
confidence and trust
among the public.
• Improvement public concerns over nutrigenomics are
relevant to science and to the food industry

15. Reference
• Neeha VS, Kinth P. Nutrigenomics research: a
review. Journal of Food Science and Technology.
2013;50(3):415-428. doi:10.1007/s13197-012-0775-z.
• N. M. R. Sales, P. B. P., 2 andM. C. Goersch3. (2014).
Review Nutrigenomics: Definitions and Advances of This
New Science. Journal of Nutrition and Metabolism,
2014.