Rogier Van der Weyden was a 15th century Flemish painter who was a student of Robert Campin and later rivaled his fame. This painting depicts Saint Luke drawing the Virgin Mary while she breastfeeds the Christ child, commissioned by the artists' guild of Brussels to honor their profession. It is believed Van der Weyden used his own face as a model for Saint Luke, reflecting the increasing self-awareness and professional identity of artists. The scene takes place in a contemporary Flemish interior with a view of a landscape outside, typical of Flemish style.