The document summarizes information about various pharmaceutical drugs and formulations. It provides monographs for over 100 drugs, including their uses, estimation methods, and key details. The monographs cover a wide range of drug classes and therapeutic areas, such as antivirals, antibiotics, anticonvulsants, antihypertensives, and more. The Indian Pharmacopoeia aims to standardize quality control testing for pharmaceutical products in India.

1. BY-
MADHAVI GUPTA
M.PHARM 1ST SEM
PHARMACEUTICS

2.  In pre independence days, British Pharmacopeia was used in India.
 The colonial addendum of BP 1898 was published in 1900 appeared
as Government of India edition in 1901.
 In 1946 Government of India issued one list known as ‘The Indian
Pharmacopeia list’
 Committee under chairmanship of Sir R. N. Chopra along with
other nine members prepared ‘The Indian Pharmacopeia list’
 It was prepared by Dept. of Health, Govt. of India, Delhi in 1946.
 In 1948 Government of India appointed an Indian Pharmacopeia
committee for preparing ‘Pharmacopeia of India’
 Tenure of this committee was five years.
 Indian Pharmacopeia committee under chairmanship of Dr. B. N.
Ghosh Published first edition of IP in 1955.

3.  The Indian Pharmacopoeia 2014 is presented in four volumes. The scope of
the Pharmacopoeia has been extended to include additional anticancer
drugs & antiretroviral drugs and formulations, products of biotechnology,
indigenous herbs and herbal products, veterinary vaccines.
 The IP 2014 incorporates 2550 monographs of drugs out of which 577 are
new monographs consisting of APIs, excipient, dosage forms and herbal
products etc.
 This edition containing 313 New Monographs on drug substances, Dosage
forms & Pharmaceutical aids (A to Z), 43 New Drugs Substances
Monographs, 10 Antibiotic Monographs, 31 Herbal Monographs, 05
Vaccines & immunosera for human use, 06 Insulin Products, 07
Biotechnology Products etc. along with the 19 new General Chapters.
 19 New Radiopharmaceutical Monographs & 1 General chapter is first
time being included in this edition

4. ACICLOVIR CREAM BENZOYL HCl TABLET CALCIUM CARBONATE
TABLETS
ACICLOVIR DISPERSIBLE
TABLET
BETAMETHASONE VALERATE
CREAM
CARBAMAZEPENE
PROLONGED RELEASE TAB
ACICLOVIR EYE OINTMENT BETAXOLOL EYEDROP CARBOPLATIN INJECTION
ACICLOVIR ORAL
SUSPENSION
BEZAFIBRATE TABLET CARBOXY METHYL
EYEDROPS
ACITRETIN CAPSULES BICALCUTAMIDE TABLET CARISOPRODOL TABLET
ADEFOVIR TABLET BISACODYL GASTRO-
RESISTANT TABLET
CEFACTOR PROLONG
RELEASE TABLET
ASPIRIN GASTRO- RESISTANT
TABLET
CABERGOLINE TABLET CEFPIROME INJECTION
AZELASTINE EYE DROPS CAFFEINE CITRATE ORAL
SOLUTION
CELIPROLOL TABLET
BAMBUTEROL TABLET CALCIPOTRIOL OINTMENT CETRIMIDE EMULSIFYING
OINTMENT
BENAZEPRIL
HYDROCHLORIDE TABLET
CALCITONIN INJECTION CHLORHEXIDINE INJECTION

5. ERLOTINIB TABLET FLUMAZENIL INJECTION
DALTEPARIN SODIUM
INJECTION
ETHAMBUTOL INJECTION FLURAZEPAM CAPSULE
DESMOPRESSIN INTRANASAL
SOLUTION
ETHOPHYLLINE &
THEOPHYLLINE TABLET
FLURBIPROFEN EYEDROP
DICLOFENAC PROLONGED
RELEASE TABLET
ETIDRONATE TABLET FLUTAMIDE TABLET
DILTIAZEM INJECTION ETORICOXIB TABLET FLUTICASONE CREAM
DIVIVEFRINE EYEDROPS EZETIMIBE TABLET FLUTICASONE NASAL SPRAY
DIPYRIDAMOLE TABLETS FACICLOVIR TABLET FLUTICASONE OINTMENT
DIVALPROEX PROLONGED
RELEASE TABLET
FLAVOXATE TABLET FLUVASTIN CAPSULE
DOBUTAMINE INJECTION FLUCLOXACILLIN CAPSULE FOSINOPRIL SODIUM TABLET
DOMPERIDONE SUSPENSION FLUCLOXACILLIN ORAL
SOLUTION
GEMCITABINE INJECTION
DOPAMINE INJECTION FLUDARABINE PHOSPHATE
INJECTION
GEMFIBROZIL CAPSULE
DOXAPRAM INJECTION FLUMAZENIL INJECTION GLUTARALDEHYDE SOLUTION
EPHEDRINE NASAL DROPS FLUROMETHOLONE EYEDROP STRONG GLUTARALDEHYDE
SOLUTION
EPINASTINE EYEDROP FLUPENTIXOL INJECTION GLYCERIN ORAL SOLUTION

6. HYDROCORTISONE ACETATE
CREAM
METOPROLOL INJECTION ORNIDAZOLE INJECTION
HYDROXYCHLOROQUINE
TABLET
MESALAZINE PROLONGED
RELEASE TABLET
OXACILLIN CAPSULES
HYDROXYZINE TABLET MIDAZOLAM INJECTION PARACETAMOL INFUSION
IMATINIB TABLET MIDAZOLAM ORAL SOLUTION PAROXETINE TABLET
INVERT SYRUP MIFEPRISTONE TABLET PHENYRAMIDOL TABLET
IRBESARTAN AND
HYDROCHLOROTHIAZIDE
TABLET
LITHIUM CARBONATE
PROLONGED RELEASED
TABLET
PARACETAMOL PAEDRIATIC
ORAL SUSPENSION
IRON AND FOLIC ACID
TABLET
MISOPROSTOL TABLET POTASSIUM CHLORIDE FOR
INJECTION
IVERMECTIN INJECTION MITOMYCIN TABLET PROGESTERONE INJECTION
LABETALOL INJECTION MOXIFLOXACIN EYEDROP PYRIDOSTIGMINE INJECTION
LAMIVUDINE, NEVRAPINE,&
ZIDOVUDINE PAEDRIATIC
DISPERSIBLE TABLET
NICORANDIL PROLONGED
RELEASE TABLET
PREDNISOLONE SOD.
PHOSPHATE EYEDROP
LAPATINIB TABLET MUPIROCIN OINTMENT RAECADOTRIL CAPSULE
LEFLUNOMIDE TABLET NICORANDIL TABLET REPAGLITINIDE TABLET
LEVOFLOXACIN INJECTION OFLOXACIN ORAL
SUSPENSION
PROPYLIODONE INJECTABLE
OIL SUSPENSION
LORAZEPAM INJECTION LORAZEPAM TABLET RITODRINE INJECTION

7. RITODRINE TABLET TRANEXAMIC ACID INJECTION
SAQUINAVIR CAPSULE TRANEXAMIC ACID TABLET
SELEGINILE TABLET TRICLOFOS ORAL SOLUTION
SERTRALINE TABLET URSODEOXYCHOLIC ACID TABLET
SILVER SULPHADIAZINE CREAM VECURONIUM BROMIDE INJECTION
SOD. NITROPRUSSIDE INJECTION VOGLIBOSE DISPERSIBLE TABLET
SOD. VALPROATE GASTRO RESITANT
TABLET
VOGLIBOSE TABLET
SORAFENIB TABLET ZOPICLONETABLET
SULPRIDE TABLET ZUCLOPENTHIXOL ACETATE
TENOFOVIR FUMARATE, LAMIVUDINE &
EFAVIRENZ TABLET
EPTIFIBATIDE INJECTION
HYDROCORTISONE OINTMENT

8. ACICLOVIR-
It is an Antiviral medication.
 Used for the treatment of Herpes Simplex virus infection, Chickenpox and
Shingles.
 Estimation is done by UV Spectrophotometric (253nm)
ACITRETIN-
Second generation Oral Retinoid.
 Typically used for Psoriasis.
 Estimation is done by HPLC.
ADEFOVIR-
Orally administered Nucleotide Analog Reverse transcriptase Inhibitor.
Estimated by Spectrophotometric, Liquid chromatography as well as Mass
spectroscopy.
It is used to treat infections with Hepatitis B virus and Herpes
simplex virus.

9. ASPIRIN-
It is a Non steroidal Anti-inflammatory drug (NSAID)
Used to treat Pain, Fever and Inflammation.
Estimation is done by Back Titration using starch as a Indicator.
AZELASTINE-
It is a Potent, second generation selective Histamine (H1) Antagonist.
Used as first line therapy of mild intermittent and moderate persistent
Rhinitis.
Done by HPLC.
BAMBUTEROL-
It is a long-acting β adrenoceptor agonist
 used in the treatment of asthma.
 It is a prodrug of Terbutaline.
Done by HPLC.

10. BENAZEPRIL-
It is a Angiotensin-converting enzyme (ACE) inhibitors.
 used alone or in combination with other medications to treat high blood
pressure.
Done by UV Spectrophotometric method.
BETAMETHASONE VALERATE-
 It is in the peroxide family of chemicals.
 It is used to treat mild to moderate acne.
Done by HPLC.
BETAXOLOL-
 It is a selective beta1 receptor blocker.
 used in the treatment of hypertension and glaucoma.
Done by HPLC.

11. BEZAFIBRATE-
It is a fibrate drug.
 used as a lipid-lowering agent to treat hyperlipidaemia. It helps to lower LDL
cholesterol and triglyceride in the blood, and increase HDL.
Done by Reverse HPLC.
BICALCUTAMIDE-
It is an antiandrogen medication.
 It is used to treat Prostate Cancer.
Done by UV spectrophotometer
BISACODYL-
It is an organic compound, and a derivative of triphenylmethane.
 Used as a Stimulant Relaxant, It is typically prescribed for relief of
constipation and for the management of neurogenic bowel dysfunction.
Done by IR spectroscopy.

12. CABERGOLINE-
It is an ergot derivative, potent dopamine receptor agonist on D2 receptors.
 used as a first-line agent in the management of prolactinomas and in mono
therapy of Parkinsonism.
Done by IR spectroscopy.
CAFFEINE CITRATE-
It is a citrate salt of caffeine.
 used to treat a lack of breathing in premature babies.
Done by IR Spectroscopy.
CALCIPOTRIOL-
 It is a synthetic derivative of calcitriol, a form of vitamin D.
 used in the treatment of Chronic plague of psoriasis.
 Done by HPLC.

13. CALCITONIN-
 Man made Hormone.
 used to treat certain bone problems (e.g., Paget's disease, postmenopausal
osteoporosis) and to reduce high blood levels of calcium.
 Done by IR spectroscopy.
CARBAZEPINE-
It is an anticonvulsant.
 used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic
neuropathy and also used in bipolar disorder.
Done by UV Spectrophotometer.
CARBOPLATIN-
It is a chemotherapy medication.
 used to treat a number of forms of cancer like- ovarian cancer, lung cancer,
head and neck cancer, brain cancer & neuroblastoma.
Done by HPLC.

14. CARISOPRODOL-
It is a Muscle Relaxant.
 used to relax certain muscles in your body and relieve the discomfort caused
by acute (short-term), painful muscle or bone conditions
Done by liquid chromatography
CEFACLOR-
It is a second-generation cephalosporin antibiotic.
used in treatment of some infection caused by bacteria such as pneumonia.
Done by IR Spectroscopy.

15. CEFPIROME-
 It is a fourth-generation cephalosporin.
 Highly active against Gram –ve bacteria.
Done by UV spectrophotometer.
CELIPROLOL-
 It is a selective β1 receptor antagonist, but a β2 receptor partial agonist. It is
also a weak α2 receptor antagonist.
 Used in the treatment of High blood pressure.
Done by Reverse phase HPLC
CETRIMIDE-
It is a mixture of different quaternary ammonium salts including cetrimonium
bromide (CTAB).
 Used as an Antiseptic and used as an alcohol denaturant.
Done by UV spectrophotometer.

16. CHLORHEXIDINE-
It is a disinfectant and antiseptic .
 used for skin disinfection before surgery and to sterilize surgical instruments.
Done by HPLC method.
DALTEPARIN SODIUM-
 It is low molecular weight Heparin
 used for prophylaxis or treatment of deep vein thrombosis and pulmonary
embolism.
 Done by IR spectroscopy.
DESMOPRESSIN-
used to treat diabetes insipid us, bedwetting, hemophilia A, von Willebrand
disease, and high blood urea levels.
Done by Reverse phase HPLC

17. DILTIAZEM-
 It is a nondihydropyridine (non-DHP) calcium channel blocker
 used in the treatment of hypertension, angina pectoris, and some types of
arrhythmia.
Done by UV Spectrophotometric.
DIPIVEFRINE-
 Prodrug of Epinephrine.
 used to treat open-angle glaucoma.
Done by IR spectroscopy.
DIPYRIDAMOLE-
 used to dilate blood vessels in people with peripheral arterial disease and
coronary artery disease.
Done by UV Spectrophotometric.

18. DIVALPROEX-
 It is an Anticonvulsant.
 Used in the treatment of certain types of seizures (epilepsy), manic phase of
bipolar disorder (manic-depressive illness), and migraine headaches.
Done by Gas Chromatography.
DOBUTAMINE-
 It is a sympathomimetic drug.
 used in the treatment of heart failure and cardiogenic shock.
Done by UV Spectrophotometer.
DOMPERIDONE-
 It is a peripherally selective dopamine D₂ receptor antagonist.
 Used as an Antiemetic.
Done by UV Spectrophotometer.

19. DOPAMINE-
 It is a neurotransmitter and an organic chemical of the catecholamine and
phenethylamine.
 Used in the treatment of Parkinsonism Disorder.
DOXAPRAM-
 Respiratory Stimulant.
 Used to stimulate an increase in tidal volume, and
respiratory rate.
EPHEDRINE-
 Obtain from Plant Ephedra.
 used to prevent low blood pressure during spinal anesthesia. It has also been
used for asthma, narcolepsy & Obesity

20. EPINASTINE-
 It is a second generation antihistamine and mast cell stabilizer.
 used in eye drops to treat allergic conjunctivitis.
 Produced by Allergen.
EPTIFIBATIDE-
 It is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class
 cyclic heptapeptide derived from a protein found in the venom of the
southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the
class of the arginin-glycin-aspartat-mimetics.
ERLOTINIB-
 It is a receptor Tyrosine kinase inhibitor.
 used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and
several other types of cancer

21. ETHAMBUTOL- Used in the treatment of Tuberculosis.
ETIDRONATE-
 Treatment for Paget's disease
also used sometimes to treat and prevent osteoporosis caused by corticosteroids
ETORICOXIB-
 Selective COX-2 inhibitor
 Used for the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis,
ankylosing spondylitis, chronic low back pain, acute pain, and gout.
EZETIMIBE- lowers plasma cholesterol levels

22. FAMCICLOVIR-
Guanosine analogue antiviral drug
used for the treatment of various herpes virus infections, most commonly for herpes zoster
(shingles)
FLAVOXATE-
It is an anticholinergic with antimuscarinic effects
used to treat urinary bladder spasms
FLUXACILLIN-
It is a narrow spectrum beta-lactam antibiotic of the penicillin class
used to treat infections caused by susceptible Gram-positive bacteria.
FLUDARABINE- Chemotherapy medication.
used in the treatment of leukemia and lymphoma.
FLUMAZENIL- selective benzodiazepine receptor antagonist.
used as an antidote in the treatment of benzodiazepine overdoses.

23. FLURMETHOLONE- synthetic glucocorticoid
used in the treatment of inflammatory eye diseases
FLUPENTIXOL- typical Antipsychotic drug of the thioxanthene class.
long-acting injection given once in every two or three weeks to individuals with
schizophrenia
FLURAZEPAM- It is a benzodiazepine derivative
it is used for short-term treatment of patients with mild to moderate insomnia
FLUTICASONE- synthetic glucocorticoid
used as topical anti-inflammatory and inhaled corticosteroids.
FLUVASTATIN- member of the statin drug class
used to treat hypercholesterolemia and to prevent cardiovascular disease.
FLUVOXAMINE- selective serotonin reuptake inhibitor(SSRI) and σ1 receptor
agonist. Used for the treatment of obsessive–compulsive disorder , major depressive
disorder and anxiety disorders

24. FLURBIPROFEN- Nonsteroidal anti-inflammatory drugs
indicated as a pre-operative anti-miotic(in an ophthalmic solution) , orally for arthritis or
dental pain.
FOSINIPRIL- Angiotensin converting enzyme (ACE) inhibitor
used for the treatment of hypertension and some types of chronic heart failure
GEMCITABINE- It is a chemotherapy medication used to treat a number of types of
cancer
GEMFIBROZIL- belongs to a group of drugs known as Fibrates
It is used to lower lipid level.
HYDROCORTISONE- hormone Cortisol
Used in Adrenocortical insufficiency, Adrenogenital syndrome, high blood calcium,
thyroiditis, rheumatoid arthritis, dermatitis, asthma, and COPD
HYDROXYZINE- First-generation Antihistamine
Used for the treatment of severe cases of itching, hyperalgesia and motion sickness.

25. IMATINIB- chemotherapy medication
used to treat cancer specifically chronic myelogenous leukemia and acute lymphocytic
leukemia
IRBESARTAN- It is an angiotensin II receptor antagonist used mainly for the treatment
of hypertension
IVERMECTIN- It is in list of essential medicines.
used to treat head lice, scabies, river blindness, strongyloidiasis, lymphatic filariasis
LABETALOL- alpha and beta adrenergic antagonist
used to treat high blood pressure
LAMIVUDINE- It is an antiretroviral medication used to prevent and treat HIV/AIDS
also used to treat Hepatitis-B
LAPATINIB- It is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and
epidermal growth factor receptor(EGFR) pathways
It is used in combination therapy for HER2-positive breast cancer

26. ZUCLOPENTHICOL- It as a typical antipsychotic.
medication used to treat schizophrenia and other psychoses
ZOPICLONE- It is a non benzodiazepine hypnotic agent
used in the treatment of insomnia.
VOGLIBOSE- It is an alpha-glucosidase inhibitor
used for lowering post-prandial blood glucose levels in people with diabetes mellitus.
URSODEOXYCHOLIC ACID- one of the secondary bile acid
Used in the treatment of primary biliary cholangitis (PBC)
TRICLOFOS- sedative drug used rarely for treating insomnia
TRANEXAMIC ACID- Used to treat or prevent excessive blood loss from major
trauma, post partum bleeding, surgery, tooth removal, nose bleeds, and heavy
menstruation.

27. SULPRIDE- It is an Atypical Antipsychotic drug
used mainly in the treatment of psychosis associated with schizophrenia and major
depressive disorder, anxiety and mild depression.
SORAFENIB- It is a kinase inhibitor drug.
Used for the treatment of advanced renal cell carcinoma, hepatocellular carcinoma, and
radioactive iodine resistant advanced thyroid carcinoma.
VALPROATE- Include in the list of Essential medication.
used to treat epilepsy and bipolar disorder and to prevent migraine headaches
NITROPRUSSIDE- It is used to lower blood pressure.
SULPHADIAZINE- It is an antibiotic.
Used in the treatment of choice for toxoplasmosis, otitis media, prevention of rheumatic
fever, chancroid, Chlamydia and infections by Haemophilus influenzae
SERTRALINE- an antidepressant of the selective serotonin reuptake inhibitor class.
Used in depressive disorder, obsessive–compulsive disorder, panic disorder and social
anxiety disorder.

28. SELEGILINE- selective irreversible MAO-B inhibitor
used to reduce symptoms in early-stage Parkinson's disease and depression.
RITODRINE- It is a tocolytic drug used to stop premature labor .
RAECADOTRIL- It is an antidiarrheal drug used in the treatment of diarrhea.
PYRIDOSTIGMINE- Acetylcholinesterase inhibitor
Used in the treatment of myasthenia gravis
PROGESTERONE- Neurosteroid used mainly in hormone replacement therapy (HRT)
for menopause, hypogonadism and transgender women
PREDNISOLONE- steroid medication used to treat certain types of allergies,
inflammatory conditions, autoimmune disorders, and cancers.
PAROXETINE- antidepressant of the selective serotonin reuptake inhibitor(SSRI) class.
Used to treat major depressive disorder obsessive-compulsive disorder, social anxiety
disorder, panic disorder, posttraumatic stress disorder, generalized anxiety disorder and
premenstrual dysphoric disorder

29. NICORANDIL- It is a vasodilator drug used to treat Angina Pectoris.
MUPIROCIN- It is a topical antibiotic
useful against superficial skin infections such as impetigo or folliculitis,
And to treat infection caused by methicillin-resistant S. aureus.
MISOPROSTOL- Used to start labor, cause an abortion, prevent and treat
stomach ulcers, and treat postpartum bleeding.
MIFEPRISTONE - Used with Misoprostol to bring about an abortion.
MIDAZOLAM - Used for anesthesia, procedural sedation, trouble sleeping,
and severe agitation.
METOPROLOL - Selective β1 receptor blocker type.
Used to treat high blood pressure, chest pain due to poor blood flow to the heart,
and a number of conditions involving an abnormally fast heart rate.

30. MESALAZINE - It is an aminosalicylate anti-inflammatory drug.
used to treat inflammatory bowel disease, including ulcerative colitis or
inflamed anus or rectum, and to maintain remission in Cohn's disease.
LORAZEPAM - Benzodiazepine medication.
Used to treat anxiety disorders, trouble sleeping, active seizures including status
epileptics, alcohol withdrawal, and chemotherapy induced nausea and
vomiting.