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APPROACH TO
DERMATOLOGICAL
DIAGNOSIS
DR. S.A.SHAH
FCPS, D.Dsc (UK),
M.A.A.C.S (USA)
Skin Lesions And Diagnosis
 Thorough approach to the evaluation decreases the risk of
making an in correct diagnosis or overlooking another
diagnosis
 Knowledge and appropriate use of dermatological
terminology are fundamental
continue…
 The entire mucocutaneous surface, as well as the hair and nails, should
be examined whenever reasonable.
 Diseases have characteristics morphology and distribution.
 Common pitfalls in dermatologic diagnosis exist and can be avoided.
Approach To The Patient
 Introduction
 History
 History of present illness
 Systemic review
 Past medical & surgical history
 Family history
 Social history
 Drug history
•Examination
- cutaneous
- General physical
- Loco-regional
- Systemic
 Differential diagnosis
 Provisional diagnosis
 Investigations
 Final diagnosis
 Treatment
 Follow up
HISTORY
Dermatology a visual specialty
 But In most cases, a carefully directed history is important
for :
- refining the diagnosis,
-for identifying further investigations
-and to address issues that may be important for optimal
management
continue…
 Perform a brief examination initially before taking history
 it helps to obtain streamlined and more focused history
later
continue…
Demographics
Name , Age, race, sex, occupation, residence , mode
of admission etc
Presenting complaint:
 Symptoms.
 Itch is the prime dermatological symptom
 Rash
 History of a growth
 Symptoms usually parallel development of eruption but
discordance can be diagnostically useful
History of present illness:
It includes complete detail of presenting
complaint.
History of a rash: key
questions
 When did it start?
 Did it itch, burn or hurt?
 Where on the body, did it start?
 How has it spread?
 How have individual lesions changed?
 Provocative factors?
 Previous treatments & response?
History of a growth: key questions
 How long has the lesion been present?
 Has it changed, grown, bleed, itched or failed to heal?
Systemic review
 Review of systems as indicated by
clinical situation, with particular attention to symptoms indicating a
possible connection between cutaneous signs
and disease of other organ systems.
Continue…
 e.g. rheumatic complaints: myalgias, arthralgias, Reynaud's
phenomenon,
sicca symptoms.
continue…
Review of symptoms for growth suspicious for,
or associated with malignancy.
Particular attention to symptoms of metastasis
(weight loss, fever, headache ,abdominal pain,
bone pain etc.)
continue…
 Constitutional symptoms
 “Acute illness” syndrome: headaches, chills,
 fever, weakness
 “Chronic illness” syndrome: fatigue, weakness,
anorexia, weight loss, malaise
3. Past history
 Illnesses
 Operations
 Atopic history
( asthma, hay fever, eczema)
4. Family history
 Family medical history , particularly of skin disorders and of atopy.
 Family history of skin and other cancers.
5. social history
 Social history with particular reference
to occupation, hobbies , sun exposure, tobacco smoking, alcohol use,
recreational drugs , travel, sexual orientation and exposure.
6. Drug history
 History of any drug intake.
 History of drug allergies.
LABORATORY STUDIES
Special procedures as determined by individual
clinical situation:
 Dermatoscopy
 Hand lens
 Biopsy for histopathologic & other analysis (electron
microscopy, immunofluorescence, special stains)
continue…
 Gram stain of scales , crust or exudates
 Potassium hydroxide preparation for yeast or fungi
 Tissues to be minced for bacterial and fungal culture
 Cytological preparation (tzanck smear) in vesicular &
bullous eruptions
continue…
 Swab for bacterial, fungal, viral culture
 Wood’s lamp examination of urine
for porphyrins & of hair & skin for fluorescence or for
changes in
pigmentation
 Patch testing for allergic contact dermatitis
General laboratory studies
 Hematology
 Chemistry
 Urine analysis
 Serology
 Imaging studies
Final diagnosis
 Re-examination over time
 More than one biopsy may be required for definitive diagnosis
Examination of the
dermatologic patient
Scope of the complete cutaneous examination:
 it includes examining entire skin
 Identification of potentially harmful lesions
 Identification of benign lesion
continue…
 Finding hidden clues to diagnosis
(e.g. scabies lesions on penis,
psoriatic plaques on buttocks,
Wickham striae of lichen planus
on buccal mucosa.)
The pre-requisite of dermatologic diagnosis is recognition of
 the type of skin lesion
 the color
 margins
 Consistency
 shape
 arrangement
 distribution of lesions
Recommended tools for skin examination
 A magnifying tool such as loupe, magnifying glass,
dermatoscope.
 A bright focused light
 Glass slides
 Alcohol pads to remove scales or surface oil
 Gauze pads or tissues with water
 Gloves
 A Ruler for measuring lesions
 A surgical blades for scraping or incising lesion
 Camera for photographic documentation
 A wood’s lamp for highlighting pigmentary changes
Techniques for dermatologic physical
examination
 Inspection :
Observe the patient at a distance for any kind of
asymmetry , obesity, pallor, fatigue , jaundice.
Next examine the patient in a systematic way
from head to toe.
Palpation:
Palpate the patient for any kind of mass ,
growth,
whether they are soft ,fleshy, firm, tender
fluid-filled.
Palpation:
Palpate the lesion for ,
 Texture
 Consistency
 Thickness
 Tenderness
 temperature
continue…
After completing the examination ,
it is important to document the
findings

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New Approach to Dermatological Diagnosis

  • 2. Skin Lesions And Diagnosis  Thorough approach to the evaluation decreases the risk of making an in correct diagnosis or overlooking another diagnosis  Knowledge and appropriate use of dermatological terminology are fundamental
  • 3. continue…  The entire mucocutaneous surface, as well as the hair and nails, should be examined whenever reasonable.  Diseases have characteristics morphology and distribution.  Common pitfalls in dermatologic diagnosis exist and can be avoided.
  • 4. Approach To The Patient  Introduction  History  History of present illness  Systemic review  Past medical & surgical history  Family history  Social history  Drug history
  • 5. •Examination - cutaneous - General physical - Loco-regional - Systemic  Differential diagnosis  Provisional diagnosis  Investigations  Final diagnosis  Treatment  Follow up
  • 6. HISTORY Dermatology a visual specialty  But In most cases, a carefully directed history is important for : - refining the diagnosis, -for identifying further investigations -and to address issues that may be important for optimal management
  • 7. continue…  Perform a brief examination initially before taking history  it helps to obtain streamlined and more focused history later
  • 8. continue… Demographics Name , Age, race, sex, occupation, residence , mode of admission etc
  • 9. Presenting complaint:  Symptoms.  Itch is the prime dermatological symptom  Rash  History of a growth  Symptoms usually parallel development of eruption but discordance can be diagnostically useful
  • 10. History of present illness: It includes complete detail of presenting complaint.
  • 11. History of a rash: key questions  When did it start?  Did it itch, burn or hurt?  Where on the body, did it start?  How has it spread?  How have individual lesions changed?  Provocative factors?  Previous treatments & response?
  • 12. History of a growth: key questions  How long has the lesion been present?  Has it changed, grown, bleed, itched or failed to heal?
  • 13. Systemic review  Review of systems as indicated by clinical situation, with particular attention to symptoms indicating a possible connection between cutaneous signs and disease of other organ systems.
  • 14. Continue…  e.g. rheumatic complaints: myalgias, arthralgias, Reynaud's phenomenon, sicca symptoms.
  • 15. continue… Review of symptoms for growth suspicious for, or associated with malignancy. Particular attention to symptoms of metastasis (weight loss, fever, headache ,abdominal pain, bone pain etc.)
  • 16. continue…  Constitutional symptoms  “Acute illness” syndrome: headaches, chills,  fever, weakness  “Chronic illness” syndrome: fatigue, weakness, anorexia, weight loss, malaise
  • 17. 3. Past history  Illnesses  Operations  Atopic history ( asthma, hay fever, eczema)
  • 18. 4. Family history  Family medical history , particularly of skin disorders and of atopy.  Family history of skin and other cancers.
  • 19. 5. social history  Social history with particular reference to occupation, hobbies , sun exposure, tobacco smoking, alcohol use, recreational drugs , travel, sexual orientation and exposure.
  • 20. 6. Drug history  History of any drug intake.  History of drug allergies.
  • 21. LABORATORY STUDIES Special procedures as determined by individual clinical situation:  Dermatoscopy  Hand lens  Biopsy for histopathologic & other analysis (electron microscopy, immunofluorescence, special stains)
  • 22. continue…  Gram stain of scales , crust or exudates  Potassium hydroxide preparation for yeast or fungi  Tissues to be minced for bacterial and fungal culture  Cytological preparation (tzanck smear) in vesicular & bullous eruptions
  • 23. continue…  Swab for bacterial, fungal, viral culture  Wood’s lamp examination of urine for porphyrins & of hair & skin for fluorescence or for changes in pigmentation  Patch testing for allergic contact dermatitis
  • 24. General laboratory studies  Hematology  Chemistry  Urine analysis  Serology  Imaging studies
  • 25. Final diagnosis  Re-examination over time  More than one biopsy may be required for definitive diagnosis
  • 26. Examination of the dermatologic patient Scope of the complete cutaneous examination:  it includes examining entire skin  Identification of potentially harmful lesions  Identification of benign lesion
  • 27. continue…  Finding hidden clues to diagnosis (e.g. scabies lesions on penis, psoriatic plaques on buttocks, Wickham striae of lichen planus on buccal mucosa.)
  • 28. The pre-requisite of dermatologic diagnosis is recognition of  the type of skin lesion  the color  margins  Consistency  shape  arrangement  distribution of lesions
  • 29. Recommended tools for skin examination  A magnifying tool such as loupe, magnifying glass, dermatoscope.  A bright focused light  Glass slides  Alcohol pads to remove scales or surface oil  Gauze pads or tissues with water
  • 30.  Gloves  A Ruler for measuring lesions  A surgical blades for scraping or incising lesion  Camera for photographic documentation  A wood’s lamp for highlighting pigmentary changes
  • 31. Techniques for dermatologic physical examination
  • 32.  Inspection : Observe the patient at a distance for any kind of asymmetry , obesity, pallor, fatigue , jaundice. Next examine the patient in a systematic way from head to toe.
  • 33. Palpation: Palpate the patient for any kind of mass , growth, whether they are soft ,fleshy, firm, tender fluid-filled.
  • 34. Palpation: Palpate the lesion for ,  Texture  Consistency  Thickness  Tenderness  temperature
  • 35. continue… After completing the examination , it is important to document the findings