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Integumentary System
RESPONSE TO ALTERED INTEGUMENTARY FUNCTION
Unit Outcomes: Upon completion of this unit of study, the student will be able to:
• Safe Effective Care Environment:
• 1. Identify factors that influence injury and disease prevention ( sun exposure, environmental toxins, etc.).
• 2 . Perform thorough dermatological assessment throughout the life span.
• Health Promotion and Maintenance:
• 3. Identify healthy behaviors by the client and family ( screening exams, limiting risk taking behaviors).
• Psychosocial Integrity:
• 4. Discuss psychosocial impact of client’s altered dermatological condition ( acne, burns, rashes, tumors).
• Physiologic Integrity:
• 5. Discuss nursing implications for medications prescribed for clients with dermatologic disorders.
• 6. Develop plan of care for client with impaired skin integrity.
• 7. Explain the eight parameters of assessing a lesion.
• 8. Describe common lesions and rashes utilizing proper terminology.
• 9. Describe pre-op and post care of clients receiving dermatological surgical procedures.
• 10. Select nursing diagnoses most likely to be utilized with clients with integumentary problems.
• 11. Discuss etiology, clinical manifestations, and interventions for viral, bacterial, fungal, and parasitic skin
disorders.
Introduction: Skin in our Culture
• Defining ‘beauty’
• Language
• Costs
Functions:
• Protective Barrier
– Injury
– Microbial Invasion
– Fluid & Electrolyte Balance
– Temperature control
• Excretion
• Sensation
• Vitamin D
• Identity
Topics:
• Assessment
• Safety and preventive measures
• Nursing Implications for Pharmacologic
Management
• Nursing Implications for Nonpharmacologic
Management
• Nursing Implications for Surgical Management
• Nursing Management of Clients with Alterations
- Integument
KP’s
•Assessment
• A. Parameters of General Skin Assessment
• B. Lesions
• C. Cultural/Ethnic variations
• D. Diagnostic Testing
Thorough History
• Dx & Tx – realm of practice
– Difficult due to similarities in lesions and sx
• Differential dx requires clues
Assessment: Subjective Data
– Past Medical History
• Trauma
• Surgery
• Prior skin disease
• Jaundice
• Delayed wound healing
• Allergies
• Sun exposure
• Radiation treatments
Assessment: History
Medications
– Prescription
– OTC
– Herbals
– Name
– Length of usage
Assessment: History
• Surgery
– Cosmetic
– Biopsy
• Diet
• Health Practices
– Hygiene, products
– Sunscreen, SPF
– Complementary &
alternative medicine
• C/O symptoms
• Known exposure to
carcinogens, chemical
irritants, allergens
• Family
– Alopecia (bald)
– Psoriasis
– Skin cancer
Assessment: History
• Changes
– Skin condition
– Hair condition
– Nail condition
– Mucous membranes
• Privacy
• Carefully describe:
– Obvious changes in color and vascularity
– Presence or absence of moisture
– Edema
– Skin Lesions
– Skin integrity
• Document properly
Assessment
Parameters of General Skin Assessment
• color, temperature, moisture, elasticity,
turgor, texture, and odor.
Assessment: Inspection
• Consider Cultural and Ethnic variations
– Dark skin
• rates - skin cancer
• Difficult to assess flushing; cyanosis; jaundice
• Rashes difficult to observe
• Pseudofolliculitis
• Keloids
• Mongolian spots
• Inspection of hair
– Distribution
– Texture
– Quantity
• Inspection of nails
• Iggy page 474-475; Wilkinson 370
– Grooves
– Pitting
– Ridges
– Curvature
– Shape
Malnutrition
Anorexia nervosa
Anxiety
Hygiene
Depression
Hormones
Living conditions
Circulatory status
Chronic disease
Assessment: Inspection
Lesion Description
• Size
– Metric
• Shape
– Circumscribed
– Irregular
– Round
• Texture
– Rough
– smooth
• Configuration
– Annular
• “relating to, or
forming a ring”
– Linear
– Concentric rings
– Clustered
– Diffuse
• Effect of pressure
Lesion Description
• Distribution
– Asymmetric vs. Symmetric
– Confluent
• “flowing or coming together; also : run together”
– Diffuse
– Localized
– Solitary
– Zosteriform
• “resembling shingles”
– Satellite
Assessment: Palpation
– Edema
– Moisture
– Temperature
– Turgor
– Texture
Fever
C-V status
Respiratory status
Hormones
Hydration
Rash/ Lesion
Nutritional status
Skin cancer - most common cancer!
• Risk factors
– Fair skin
– Blue/green eyes
– Blond/red hair
– History chronic sun exposure
– Family history
– Living near the equator
– Very high/low altitudes
– Working outdoors
– Age > 60 (damage is cumulative)
Non-melanoma Skin Cancers
• Basal Cell Carcinoma
– Most common type of skin cancer
– Easily treated
– Doesn’t metastasize
– Middle age to older adults
– Symptoms
• Small slow growing papule
• Semi translucent or “pearly”
• Erosion/ulceration of center
Basal Cell Carcinoma
Medical Tx
• Excision
• Cryosurgery
• Radiation
• Topical chemotherapy
Non-Melanoma Skin Cancer
• Squamous cell
– Less common than BCC
– High cure rate with early detection
– Can be aggressive, metastasize & be fatal
– Common on lips, mouth, face and hands
• Pipe, cigar, & cigarette smoking
– Symptoms
• Firm nodule
• Scaling/ulceration
• Opaque
Squamous cell carcinoma
Medical Tx
• Excision
• Radiation
• Moh’s surgery
 (see slide #33)
• 5 FU or methotrexate intralesional
– (see slide #34)
Diagnostic & Surgical Therapy
• Simple Excision
• Excision
– Moh’s micrographic surgery
• Microscopically controlled removal of lesion
• Removes tissue in thin layers
• Can see all margins of specimen
• Preserves normal tissue
• Produces smallest wound
Drug Therapy: Topical Fluorouracil (5-FU)
– Selective toxicity for sun damaged cells (cytotoxic)
– Indications
• Premalignant skin disease (esp. actinic keratosis)
• Systemic absorption minimal
It causes painful eroded area within 4 days and must
use 1-2 times daily 2-4 weeks.
Healing up to 3 weeks after med stopped
Is photosensitizing - avoid sunlight during treatment
Will look worse before it gets better
Non-Melanoma Skin Cancers
• Actinic Keratosis (AKA Solar keratosis)
– Most common precancerous lesion
– Premalignant form of squamous cell carcinoma
– Symptoms
• Hyperkeratotoc papules/plaques on sun exposed areas
• Varied appearance
– Irregular shape
– Flat
– Indistinct borders
– Overlying scale
Actinic Keratosis
(AKA Solar keratosis)
Medical Tx:
•Cryosurgery
 (see slide #37)
•5 FU
•Surgical removal
•Retin A
•Chemical peels
Cryosurgery
– Subfreezing temps for surgery (liquid nitrogen)
• Lesion becomes red & swollen, blisters, then scabs; falls off
in 1-3 weeks
• Minimal scarring
– Indications
• Genital warts
• Seborrheic keratosis
• Actinic keratosis
Malignant Melanoma
• 1/3 of all melanoma occur in existing nevi
or moles
– Any sudden or progressive change in size,
color or shape of a mole should be checked
Malignant Melanoma
• Can metastasize anywhere
• Most deadly of skin cancers
• Causes
– UV radiation
– Skin sensitivity
– Genetic
– Hormonal
– Sun exposure
– Mutation of gene (B-RAF) 70%
A B C D’s of Melanoma
Asymmetry
Border irregular, edges ragged
Color varied pigmentation
• Tan, brown, black, red
Diameter > 6mm
Melanoma
Medical Tx
Depends on site, stage, age and
general health of client
– Surgery
– Chemotherapy
– Biologic Therapy
• Interferon, interleukin
– Radiation therapy
Prevention/Education
• Sunscreen
• Limit exposure
• Hat/clothes/sunglasses
• Shade
• Inspect skin regularly
Sunburn: Education
(Protect, Protect, Protect)
• Same precautions as for skin cancer.
• Don’t let clouds or cool air fool you –
Florida sun is damaging then too.
• Get out of the sun before you turn red!
• Cool skin off. Immediately!
• Hydrate!
Sunburn
• Superficial burn
• Excessive exposure to ultraviolet rays injures
dermis.
• Dilated capillaries = red, tender, edema,
blisters
• Large area = nausea, fever
Sunburn
• Redness & pain begin within a few Hours.
• Intensity may increase before subsiding.
• 3-5 days to heal
• Tx: cool bath; soothing lotions; topical
corticosteroids; fluids
Insects/Pests/Parasites
• Spiders
• Fire Ants
• Lice/Scabies
• Mosquitoes
• Scorpions
• “Sand fleas”
Infestations: Pediculosis
– Head, body or pubic lice (“crabs”)
– Parasite excrement and eggs on skin
– Nits in hair
• Waxy, don’t fall off easily
• Symptoms
• Tiny red points to papular wheal-like lesions
• Pruritis – check hairline
• Secondary excoriation
Pediculosis
Medical tx
• Pyrethrins (Rid), Permethrin (Nix) or if all other
agents fail…Benzene hexachloride (Kwell)
• Contact screening
• l
Infestations: Scabies
– Skin reactions due to eggs, feces, & mite parts
– Transmitted by direct contact
• Symptoms
– Severe itching especially at HS
– Usually not on face
– Presence of burrows esp. interdigital webs & flexor
surface of wrists
– Redness, swelling, vesiculation
Scabies
Medical tx
– Topical Scabicide
– Antibiotics for 2ndary
infection
– Treat those in close
proximity
– Clothing & linens – hot
water and detergent
Drug Therapy: Antiparasitics
– Pediculicides
• Pyrethrins (RID)
• Permethrin (NIX)
– Scabicide & Pediculicide
• Lindane (Kwell, Scabene)
– Cream, lotion
– Shampoo
 nit comb
– Adverse effects
 Rash, rare CNS toxicity
Plants in FL that irritate skin
• Poinsettia, Croton
• Milky sap can cause skin irritation
• Oleander
– Touching the plant is not dangerous, but prolonged contact can
irritate the skin.
• Poison Ivy , Brazilian Pepper
– Touching the leaves or oil from the plant can cause an itchy rash
with blisters.
Brazilian Pepper
Poison Ivy:
Virginia Creeper
Drug Therapy
• Topical Corticosteroids
– Anti-inflammatory, antipruritic
• Low potency (hydrocortisone)
– Slower acting
– Can be used longer without serious side effects
– Ointment most efficient
– Higher potency, long term, systemic use is different tx
– Intralesional
• Reservoir of med effects lasts several weeks to months
• Indications
– Psoriasis
– Alopecia
– Cystic acne
– Hypertrophic scars and keloids
– Systemic
• Undesirable adverse effects – Lilley 6th ed. Page 869
• Short term therapy – poison ivy
• Long term therapy – chronic bullous diseases
Corticosteroids
Triamcinolone (Kenalog)
Bases for Topical Medications
• Powder
– Promotes dryness
– Good for antifungals
• Lotion
– Cooling and drying with residual powder film
– Good for pruritic eruptions
• Cream
– Emulsion of oil and water
– Lubrication and protections
• Ointment
– Oil with water in suspension
– Lubrication
– Most efficient delivery system
• Paste
– Mixture of powder and ointment
– Drying
– Moisture absorption
Nursing Management:
RN as skin “symptomologist”
• Dry skin
– Elderly; Infants
• Itchy skin
• Broken skin
• Prevention of secondary infections
Nursing Management: Dry skin
• Manifestations
• Interventions:
– Elder –
• Fewer total baths
• Lotions & Mild soaps
• Hydrate!
Nursing Management: Itchy skin
• Control of pruritis
– Keep cool
– No rubbing
– Moisturize
– Systemic antihistamines
– Wet dressing
– Topical steroids
– Menthol, Camphor, Phenol numb itch receptors
– Oatmeal baths
Nursing Management: itch
• Baths
– For large body areas
– Has sedating and antipruritic effect
– Oilated oatmeal (Aveeno), potassium permangenate,
sodium bicarb
– Temp comfortable to client
– Soak 15-20 mins 3-4 times daily
– Pat dry, no rubbing
– apply moisturizers or meds after baths
Nursing Management
• Wet dressings
– Indications
• Skin weepy from infection/inflammation
• Relieves itching
• Debrides wound
• Increases penetration of topical meds
• Relieves discomfort
• Enhances removal of scabs, crusts, and exudate
Wet dressings
Procedure
•Clean solution and gauze
•Squeeze until not dripping
•Apply to affected area, avoid normal tissue
•Leave in place 10-30 minutes 2-4 times a
day
•Discontinue if skin macerates (“to soften”)
Nursing Management: Protect
• Protect intact skin!
– Turn at least q2h
– Reposition frequently
– Alleviate pressure
– Hydration
– Mechanical intervention
– Rx
Nursing Management:
Psychological support
• Chronic skin conditions
– Emotional stress
– Self concept alterations
– Body image changes
Nursing Interventions:
Psychological support:
– Support client
– Allow verbalizations of frustrations
– Reinforce treatment
– Support groups
– Help with camouflage
Diagnostic Testing
Biopsy
– Punch
– Incisional
– Excisional
– Shave
RN Responsibilities
– Informed Consent
– Prep site
– Assist with procedure
– Apply dressing
– Post-op instructions
– Properly ID specimen
Diagnostic Testing
• Cultures
– Diagnose fungal, bacteria, viral infections
– KOH (Potassium Hydroxide)
• Fungus
• Sample collection
– Skin scraping
– Swabbing
– Meticulous labeling
Diagnostic Testing
• Woods Light
– Organisms fluoresce
• Pseudomonas
• Fungus
• Vitiligo
• Mineral oil slides
– Infestations
• Patch test
– Allergen testing
Dermatological Interventions
• Phototherapy
– UVA & UVB (UVL)
– Ultraviolet wavelengths cause erythema,
desquamation, and pigmentation
– Enhance with psoralem (photosensitizing)
• Treatment for
• Psoriasis
• Atopic dermatitis
• Vitiligo
Phototherapy
• Adverse effects
– Basal or squamous cell Ca
– Burns
– Erythema
– Teach patients to avoid further sun exposure &
photosensitizing drugs
– Wear eye protections as psoralem absorbed by lens of eye
Dermatological Interventions
• Radiation Therapy
– Indications
• Cutaneous malignancies
– Advantages
• Produces minimal damage to surrounding tissues
– Adverse effects
• Permanent hair loss (alopecia) to irradiated areas
• Telangiectasia
• Atrophy
• Hyperpigmentation / depigmentation
• Ulceration
• BCC and SCC
y.
Dermatological Interventions
• Laser Therapy (CO2, Argon)
– Cuts, coagulates, & vaporizes tissue
– No cumulative tissue damage
• Indications
– Coagulation of vascular lesions
– Skin resurfacing
– Removal birthmarks
– BCC
– Keloids
– Plantar warts
Diagnostic & Surgical Therapy
• Skin Scraping
– Scalpel
– Surface cells for microscopic inspection
• Electrodesication & electrocoagulation
– Electrical energy converted to heat
– Destroys tissue by burning
• Coagulates bleeding vessels
• Curettage
– Remove tissue with circular cutting edge
– Small skin tumors
• warts, seborrheic keratosis, BCC, SCC
Allergic Conditions
• Contact Dermatitis
– Delayed hypersensitivity
– Lesions 2-7 days after antigen exposure
• Manifestations
– Red, hive-like papules and plaques
– Sharply circumscribed
– Vesicles
– Pruritic
Contact Dermatitis
Medical Tx
– Topical corticosteroids
– Antihistamines
– Skin lubrication
– Elimination of allergen
– Systemic steroids if
severe
http://dermatology.cdlib.org/DOJvol7num1/NYUcases/contact/joe.html
Drug Therapy: Antihistamines
• Compete with histamine receptor site
– Oral or Topical
• Cetitizine (Zyrtec)
– PO tabs, syrup QD
– Non-sedating
• Diphenahydramine (Benadryl)
– PO, IM, topical
• Indications
– Urticaria
– Pruritis
– Allergic reactions
Drug Therapy: Antihistamines
• Adverse effects
– Anticholinergic
– Sedation (Benadryl)
– Use with caution in older adults
• Indications
– Urticaria
– Pruritis
– Allergic reactions
• Adverse effects
– Anticholinergic
– Sedation (Benadryl)
– Use with caution in older adults
Allergic Conditions: Drug Reaction
• Manifestations
– Rash of any morphology
– Red, macular, papular
– Generalized rash with sudden onset
– Pruritic
– Can occur as late as 14 days after drug is stopped
Drug Reaction
Medical Treatment
– Discontinue drug
– Antihistamines, local or
systemic
– Corticosteroids if needed
Allergic Conditions: Atopic Dermatitis
– Cause unknown
– Begins in infancy and declines with age
• Manifestations
– Scaly, red to re-brown, circumscribed lesions
– Pruritic
– Symmetric eruptions
Atopic Dermatitis
– Topical corticosteroids
– Phototherapy
– Coal tar
corticosteroids
– Lubrication of dry skin
– Antibiotics for secondary infections
Medical Treatment
Dysplastic Nevus Syndrome
• Abnormal mole pattern
• Increased risk for melanoma
– Doubles with dysplastic nevi
• Atypical moles larger than usual (>5mm)
• Irregular borders, possibly notched
• Various variegated colors
• Most common on back
Infections of the skin
• Risk factors
– Imbalance between host and microorganism
– Broken or damaged skin; Trauma
– Systemic disease such as Diabetes
– Moisture
– Obesity
– Systemic corticosteroids, antibiotics
• Prevention
– Proper hygiene
– Good health
Infections: Herpes Simplex Virus, Type I
(AKA “cold sores/fever blisters”)
• Contagious
• Dormant – Exacerbation
• Triggers
• Symptoms -- 1st episode 3-7 days after exposure
– Painful local reaction
– Vesicles on erythematous base
– Fever, malaise
Herpes Simplex Virus, Type I
Medical Tx
– Symptom management
– Moist compresses
– Petrolatum to lesions
– Antiviral agents (Zovirax,
Famvir, Valtrex) www.treatmentsforhealth.com/.../cold-sores/
Infections: Herpes Simplex Virus, Type II
– Genital
“Most genital herpes is caused by HSV-2.” (n.l.m.-n.i.h./ Medline plus)
– Recurrence more common than oral
• Does not mean re-infection
• Symptoms
– Same as Type I
• Treatment
– Same as Type I
Iggy page 1742-1743
Infections: Herpes Varicella Virus
(chicken pox)
** Highly contagious
• No chicken pox or vaccination
• Keep those w/active lesions separated until crusted
• Symptoms
– Vesicular lesions in successive crops
• Face , scalp, spreading to trunk and extremities
 Protect eyes
 Do not squeeze pustules or crusts
• Vesicles > pustules > crusts > scars
• Postherpetic neuralgia
• Self limiting in children
Herpes Varicella Virus
Medical Tx
– Antivirals
– Symptomatic relief
Infections: Herpes Zoster
(shingles)
– Activation of varicella zoster virus
– Frequent occurrence in immunocompromised
– Potentially contagious to immunocompromised
• Symptoms
– Linear patches along dermatome
– Grouped vesicles on erythematous base
– Unilateral on trunk
– Burning pain and neuralgia
Herpes Zoster
Medical Tx
– Symptomatic
• Wet compresses
• White petrolatum to lesions
– Antiviral agents
Drug Therapy: Antivirals
– Acyclovir (Zovirax)
• Suppresses chicken pox, herpes simplex 1 & 2, shingles
• Po, IV, topical
– Valacyclovir (Valtrex)
• Herpes zoster (shingles) & genital herpes
– Vaccines
• Varivax
– Prevention of chicken pox
– Given to children > 12 mo.
• Zostivax
– HZU vaccine for adults > 60 y/o
Infections: Verruca Vulgaris
– Human papillomavirus
– Mildly contagious
• Symptoms
– Circumscribed hypertrophic flesh colored papule
• Treatment
– Scoop removal
– Liquid nitrogen therapy
– Keratolytic agents
– CO2 laser therapy
Infections: Plantar Warts
(Human papillomavirus)
• Symptoms
– Wart on “Plantar” surface (bottom) of foot –
– Cone shaped with black dots (“seeds”)
Plantar Warts
Medical Tx
– Liquid nitrogen
– Frequent paring with chemical patches
– Duct tape??????
Infections: Candidiasis (moniliasis)
– Candida albicans (Fungus)
– 50% are symptom free carriers
– Immunocompromised >> pathogenic
– Likes warm moist areas
• Mouth, vagina, skin
An opportunistic
infection
Infections: Candidiasis
– Symptoms
• Mouth
– White, cheesy plaque (milk curds)
• Vagina
– Vaginitis
– Red edematous painful vaginal wall
– White patches
– Vaginal discharge
– Pruritis
– Painful urination & intercourse
• Skin
– Diffuse papular erythematous rash
– Pinpoint satellite lesions around edges
Physiologic Integrity: 5. Discuss nursing implications for medications prescribed for clients with dermatologic disorders. 6. Develop plan of care for client with impaired skin integrity.
Candidiasis
Medical Tx: Anti-fungals
• Nystatin
– Vaginal suppository
– Oral lozenge
• Mycostatin powder, cream
• Keep skin clean dry
• Diagnosis
culture
Microscopic exam (KOH)
Infections: Fungal
• Tinea Corporis
– AKA ringworm
– Symptoms
• Annular
• well defined margins
• erythematous
Tinea Corporis
AKA ringworm
Medical Tx
•Cool compresses
•Topical antifungals
– Miconazole, clotrimazole, butenafine
Infections: Fungal
• Tinea Cruris
– AKA jock itch
– Symptoms
• Self-defined border
• In groin
– Treatment topical antifungal cream or solution
Infections: Fungal
• Tinea Pedis
– AKA athletes foot
– Symptoms
• Interdigital scaling
• Erythema
• Blistering
• Pruritis
• Pain
Medical Tx
• Topical antifungals
• Keep dry
Tinea Pedis
AKA athletes foot
Infections: Fungal
• Tinea Unguium
– Symptoms
• Brittle thickened nails
• White/yellow discoloration
Tinea Unguium
Medical Tx
• Topical antifungal cream
or solutions
• Griseofulvin (fingernails)
• Lamisil
• Debride toenails
Drug Therapy: Antifungals
– Clotrimazole (Mycelex, Lotrimin)
• Lozenges- thrush
• Cream, solution, lotion- athletes foot
• Intravaginal creams, tablets
– Miconazole (Monistat, Micotin)
• Athletes foot
• Jock itch
• Ringworm
• Yeast infections
Drug Therapy: Antifungals
– Fluconazole (Diflucan)
• PO & IV
• Excellent bioavailability
• Vaginal or systemic candidiasis
– Ketaconazole (Nizoral)
– Nystatin (Mycostatin)
– Tervinafine (Lamisil) for onychomycosis
– Tolnaftate (Tinactin)
Infections, Bacterial
• Impetigo
– Group A beta hemolytic strept or staph
– Associated with poor hygiene and low socioeconomic status
• Symptoms
– Vesiculopustular lesions
– Thick honey colored crust
– Surrounded by erythema
– Pruritic
– Contagious
• Treatment
– Systemic antibiotics
– Saline or aluminum acetate soaks
– Soap & water
– Removal of crusts
– Topical antibiotic cream
• Strept can cause glonerulonephritis if untreated
Infections: Bacterial
• Cellulitis
– Staph aureus or strept
– Can be primary or secondary infection
– Symptoms
• Hot
• Tender
• Erythematous
• Edematous
• Diffuse borders maybe malaise and fever
– Treatment
• Moist heat
• Immobilization
• Elevation
• Systemic antibiotics
• Hospitalize if severe
– Can progress to gangrene if untreated
Drug Therapy: Antibiotics
– Topical - apply lightly
• OTC
– bacitracin
– Polymixin B
• Prescription
– Mupirocin (staph)
– gentamycin (staph),
– erythromycin (staph & strept)
– clindamycin (Cleocin) (acne)
– Systemic - culture & sensitivity guides selection
• Penicillin
• Erythromycin
• Tetracycline
Benign Skin Conditions: Acne
Inflammatory disorder of sebaceous glands
• Symptoms
comedones, inflammatory lesions, papules, pustules face,
neck, upper back
• Treatment
– Comedo extraction
– Topical Benzoyl Peroxide
– Peeling and irritating agents (retinoic acid)
– Antibiotic therapy - long term
– Phototherapy
– Sun exposure
– If severe - isotretinoin (Accutane) CAUTION! Teratogenic
Drug Therapy: Acne Preparations
– Benzoyl peroxide (Benzac, Desquam-X,
PanOxyl, etc)
• Apply 1-4x day
• Effects seen 4-6 weeks
• Adverse effects
– Erythema, tenderness, dryness, pruritis, burning
– Erythromycin (Eryderm, T-Stat, Erygel)
• Macrolide antibiotic
• Adverse effects
– Erythema, tenderness, pruritis, burning
Drug Therapy: Acne Preparations
– Isotretinoin (Accutane)
• Pregnancy Category X
– Proven teratogen
– 2 contraceptive methods
– Tretinoin (Retinoic acid, Vitamin A acid, Retin-A)
• Stimulates epidermal cell turnover -> skin peeling
• Adverse effects
– Red edematous blisters, crusted skin, altered skin
pigmentation
• Avoid sun, use sunscreen
• Apply to dry skin
Benign Skin Conditions: Moles
Grouping of normal cells
• Manifestations
– Hyperpigmented areas
– Varying form and color
• Treatment
– None necessary
– Cosmetic
– Biopsy for diagnosis
Benign Skin Conditions
• Psoriasis
– Chronic dermatitis due to rapid turnover of epidermal cells
– Family predisposition
– Manifestations
– Sharply demarcated scaling plaques of
• Scalp
• Elbows
• Knees
• Palms, soles, and fingernails possible
• Treatment
– Retard growth of epidermal cells
– Topical corticosteroids
– Tar
– Anthralin topical
– Sunlight, UV light
– Alefacept (Amevive) injection
– Antimetabolites (methotrexate) or systemic retinoids for difficult
cases
Benign Skin Conditions
• Seborrheic Keratoses
– Irregularly shaped flat topped papules or
plaques
– Warty surface
– Appearance of being stuck on
– Increase in pigmentation
– No association with sun exposure
– Treatment
• Removal
– Curettage
– cryosurgery
Benign Skin Conditions: Lipoma
Encapsulated tumor of adipose tissue
Most common 40-60 years of age
• Manifestations
– Rubbery, compressible, round mass
– Variable in size
– Most common on trunk, back of neck, forearms
• Treatment
– Biopsy
– Excision if indicated
Benign Skin Conditions: Vitiligo
– Unknown cause
– Genetic connection
– Complete absence of melanocytes
– Non-contagious
• Manifestations
– Complete loss of pigment
– Variation in size an location
– Symmetric and permanent
• Treatment
– Exposure to UVA and psoralens
– Depigmentation of pigmented skin in extensive
disease
– Cosmetics and stains
Benign Skin Conditions: Lentigo
• (see fig. 26-7, Iggy page 465)
– AKA liver spots
– Increased number of melanocytes
– Related to aging and sun exposure
• Manifestations
– Hyperpigmented brown to black flat lesion
– Usually in sun exposed areas
• Treatment
– Liquid nitrogen
• Possible reoccurrence in 1-2 years
– Cosmetics
Primary Lesions
• Macule (freckles, petecchia, measles)
– Flat
– Change in color
– < 1cm
• Papule (wart, mole)
– elevated,
– Solid
– <1cm
• Vesicle (chicken pox, herpes zoster, 2nd burns)
– Elevated
– Fluid filled
– <1cm
Primary Lesions
• Bulla
– > 1cm
– Elevated
– Serous fluid filled
• Plaque (psoriasis, keratosis)
– Elevated
– Solid lesion
– >1cm
Primary Lesions
• Wheal (insect bite)
– Firm
– Edematous
– Irregular shape
– Diameter variable
• Pustule (acne, impetigo)
– Elevated
– Purulent fluid
– Varied size
Secondary Lesions
• Fissure (athletes foot)
– Linear crack from epidermis to dermis
• Scale (excess dead & flaking of skin)
– Drug eruption
– Scarlet fever
• Scar
– Increased connective tissue
– Surgical incision
– Healed wound
Secondary Lesions
• Ulcer
– Crater
– Loss of epidermis, dermis
– Pressure ulcers, chancre
• Atrophy
– Thinning of epidermis/dermis
– Ages skin, striae
• Excoriation
– Missing epidermis
– Scabies, abrasion, scratch
References:
• Chickenpox in Pregnancy. (2009). March of Dimes Foundation. Retrieved
9/25/09 from http://www.marchofdimes.com/professionals/14332_1185.asp
• Common Poisonous Plants of Florida (Florida Poison Information
Center/Tampa) @ http://www.poisoncentertampa.org/poisonous-plants.aspx
• Culbert, D. (April 14, 2005). Florida scorpions. UF/IFAS Okeechobee County
Extension Service. Retrieved 6/17/09 from
http://okeechobee.ifas.ufl.edu/News%20columns/Florida.Scorpions.htm
• Groch, J. (August 23, 2006). Guidelines for Preventing Pressure Ulcers Seen
as Suboptimal. MedPage Today. Retrieved 6/12/09 from
http://www.medpagetoday.com/Dermatology/GeneralDermatology/3982
References:
• Hembree, D. (July 21, 2008) 10 Poisonous Plants in Florida and
Safety Precautions @
http://www.associatedcontent.com/article/875395/10_poisonous_pla
nts_in_florida_and_pg2.html?cat=11
• “Herpes simplex” (May, 2009). Medline Plus Medical Encyclopedia.
Retrieved 6/15/09 from
http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/001324.htm
• Lilly, L.L., Harrington, S, & Snyder, J. (2005) Pharmacology and the
Nursing Process. (4th ed.) Mosby Elsevier. St. Louis, MS.
• Medical Dictionary (2009) Merrium – Webster Inc. Retrieved 6/15/09
from http://www.nlm.nih.gov/medlineplus/mplusdictionary.html
References:
• The Medical News. Brain eating amoeba in lake kills sixth victim.
(October 2007). Retrieved 6/16/09 from http://www.news-
medical.net/news/2007/10/07/30863.aspx
• The US Market for Skin Care Products. (May, 2005). Retrieved
6/12/09 from http://www.mindbranch.com/Skincare-Products-R567-
0199/
• Scorpion Sting Treatments. (2008). Orkin. Retrieved 6/17/09 from
http://www.orkin.com/other/scorpions/scorpion-sting-treatments
Burns
• Thermal burns
– Flame, flash, scald
• Chemical burns
– Necrotizing substances
• Acids
• Alkali
– Cleaning agents, drain cleaners, lye
• Electrical burns
– Intense heat from electrical current
The
Following
Content –
Burns –
will be
covered in
future
classes!
Save this
information for
future use.
Classification: Depth of Burn
See page 522 in Iggy text
• ABA by depth of destruction
– Partial thickness burn
• Epidermis and dermis involved
– Full thickness burn
• “burns reach through the entire dermis and sometimes into
the subcutaneous fat.” (Iggy, page 522)
• Possibly involves muscles, tendons, and bones
• *Skin cannot heal on its own.
Classification: Extent of Burn
• Total Body Surface Area (TBSF)
– (Iggy page 531)
• Berkow method
– http://www.umobile.edu/main/notes/Burn.pdf
• Rule of 9’s
– (Iggy page 531)
Classification: Location of Burns
• Severity related to location
• Complication risks related to location
• Face, neck, chest
– Respiratory complications
• Hands, feet, joints, and eyes
– Compromise ADLs
• Circumferential burns of extremities
– Circulatory compromise
Emergent Care
• A,B,C’s
• Fluid Therapy
• Wound Care
• Pain management
• Prevention of infection
Burns
What happens….
Complications of Emergent Phase
• Cardiovascular
– Arrhythmias
– Hypovolemic shock
– Impaired circulation
• Respiratory
– Upper airway burns
– Inhalation injuries
• Urinary
– Acute tubular necrosis
Acute Phase
• Fluid therapy
– Lactated Ringers per Parkland (Baxter) formula
• Wound care
– Topical silvadene, sulfamylon, bacitracin, or bactroban
– PREVENT INFECTION
• Excision and grafting
– Remove necrotic tissue
– Apply split thickness auto graft skin
• Porcine skin, cadaver skin, clients own skin, skin culture
• Nutritional therapy
– Increased fluids, proteins, vitamins A, C, E.
– Zinc, iron, folate
• Physical therapy
– Prevent contractures
• Physical and psychological comfort
Drug Therapy: Antibiotics
• Silver Sulfadiazine (Slivadene)
– Burn treatment
– QD or BID
– “frosting”
– Adverse effects
• Pain
• Itching
• Burning
Rehabilitation Phase
• Prevent and minimize contractures and
scarring!
• Cosmetic / reconstructive therapy
• Psychological support if needed

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integumentary_system.ppt

  • 2. RESPONSE TO ALTERED INTEGUMENTARY FUNCTION Unit Outcomes: Upon completion of this unit of study, the student will be able to: • Safe Effective Care Environment: • 1. Identify factors that influence injury and disease prevention ( sun exposure, environmental toxins, etc.). • 2 . Perform thorough dermatological assessment throughout the life span. • Health Promotion and Maintenance: • 3. Identify healthy behaviors by the client and family ( screening exams, limiting risk taking behaviors). • Psychosocial Integrity: • 4. Discuss psychosocial impact of client’s altered dermatological condition ( acne, burns, rashes, tumors). • Physiologic Integrity: • 5. Discuss nursing implications for medications prescribed for clients with dermatologic disorders. • 6. Develop plan of care for client with impaired skin integrity. • 7. Explain the eight parameters of assessing a lesion. • 8. Describe common lesions and rashes utilizing proper terminology. • 9. Describe pre-op and post care of clients receiving dermatological surgical procedures. • 10. Select nursing diagnoses most likely to be utilized with clients with integumentary problems. • 11. Discuss etiology, clinical manifestations, and interventions for viral, bacterial, fungal, and parasitic skin disorders.
  • 3. Introduction: Skin in our Culture • Defining ‘beauty’ • Language • Costs
  • 4. Functions: • Protective Barrier – Injury – Microbial Invasion – Fluid & Electrolyte Balance – Temperature control • Excretion • Sensation • Vitamin D • Identity
  • 5. Topics: • Assessment • Safety and preventive measures • Nursing Implications for Pharmacologic Management • Nursing Implications for Nonpharmacologic Management • Nursing Implications for Surgical Management • Nursing Management of Clients with Alterations - Integument
  • 6. KP’s •Assessment • A. Parameters of General Skin Assessment • B. Lesions • C. Cultural/Ethnic variations • D. Diagnostic Testing
  • 7. Thorough History • Dx & Tx – realm of practice – Difficult due to similarities in lesions and sx • Differential dx requires clues
  • 8. Assessment: Subjective Data – Past Medical History • Trauma • Surgery • Prior skin disease • Jaundice • Delayed wound healing • Allergies • Sun exposure • Radiation treatments
  • 9. Assessment: History Medications – Prescription – OTC – Herbals – Name – Length of usage
  • 10. Assessment: History • Surgery – Cosmetic – Biopsy • Diet • Health Practices – Hygiene, products – Sunscreen, SPF – Complementary & alternative medicine • C/O symptoms • Known exposure to carcinogens, chemical irritants, allergens • Family – Alopecia (bald) – Psoriasis – Skin cancer
  • 11. Assessment: History • Changes – Skin condition – Hair condition – Nail condition – Mucous membranes
  • 12. • Privacy • Carefully describe: – Obvious changes in color and vascularity – Presence or absence of moisture – Edema – Skin Lesions – Skin integrity • Document properly Assessment
  • 13. Parameters of General Skin Assessment • color, temperature, moisture, elasticity, turgor, texture, and odor.
  • 14. Assessment: Inspection • Consider Cultural and Ethnic variations – Dark skin • rates - skin cancer • Difficult to assess flushing; cyanosis; jaundice • Rashes difficult to observe • Pseudofolliculitis • Keloids • Mongolian spots
  • 15. • Inspection of hair – Distribution – Texture – Quantity • Inspection of nails • Iggy page 474-475; Wilkinson 370 – Grooves – Pitting – Ridges – Curvature – Shape Malnutrition Anorexia nervosa Anxiety Hygiene Depression Hormones Living conditions Circulatory status Chronic disease Assessment: Inspection
  • 16. Lesion Description • Size – Metric • Shape – Circumscribed – Irregular – Round • Texture – Rough – smooth • Configuration – Annular • “relating to, or forming a ring” – Linear – Concentric rings – Clustered – Diffuse • Effect of pressure
  • 17. Lesion Description • Distribution – Asymmetric vs. Symmetric – Confluent • “flowing or coming together; also : run together” – Diffuse – Localized – Solitary – Zosteriform • “resembling shingles” – Satellite
  • 18. Assessment: Palpation – Edema – Moisture – Temperature – Turgor – Texture Fever C-V status Respiratory status Hormones Hydration Rash/ Lesion Nutritional status
  • 19. Skin cancer - most common cancer! • Risk factors – Fair skin – Blue/green eyes – Blond/red hair – History chronic sun exposure – Family history – Living near the equator – Very high/low altitudes – Working outdoors – Age > 60 (damage is cumulative)
  • 20. Non-melanoma Skin Cancers • Basal Cell Carcinoma – Most common type of skin cancer – Easily treated – Doesn’t metastasize – Middle age to older adults – Symptoms • Small slow growing papule • Semi translucent or “pearly” • Erosion/ulceration of center
  • 21. Basal Cell Carcinoma Medical Tx • Excision • Cryosurgery • Radiation • Topical chemotherapy
  • 22. Non-Melanoma Skin Cancer • Squamous cell – Less common than BCC – High cure rate with early detection – Can be aggressive, metastasize & be fatal – Common on lips, mouth, face and hands • Pipe, cigar, & cigarette smoking – Symptoms • Firm nodule • Scaling/ulceration • Opaque
  • 23. Squamous cell carcinoma Medical Tx • Excision • Radiation • Moh’s surgery  (see slide #33) • 5 FU or methotrexate intralesional – (see slide #34)
  • 24. Diagnostic & Surgical Therapy • Simple Excision • Excision – Moh’s micrographic surgery • Microscopically controlled removal of lesion • Removes tissue in thin layers • Can see all margins of specimen • Preserves normal tissue • Produces smallest wound
  • 25. Drug Therapy: Topical Fluorouracil (5-FU) – Selective toxicity for sun damaged cells (cytotoxic) – Indications • Premalignant skin disease (esp. actinic keratosis) • Systemic absorption minimal It causes painful eroded area within 4 days and must use 1-2 times daily 2-4 weeks. Healing up to 3 weeks after med stopped Is photosensitizing - avoid sunlight during treatment Will look worse before it gets better
  • 26. Non-Melanoma Skin Cancers • Actinic Keratosis (AKA Solar keratosis) – Most common precancerous lesion – Premalignant form of squamous cell carcinoma – Symptoms • Hyperkeratotoc papules/plaques on sun exposed areas • Varied appearance – Irregular shape – Flat – Indistinct borders – Overlying scale
  • 27. Actinic Keratosis (AKA Solar keratosis) Medical Tx: •Cryosurgery  (see slide #37) •5 FU •Surgical removal •Retin A •Chemical peels
  • 28. Cryosurgery – Subfreezing temps for surgery (liquid nitrogen) • Lesion becomes red & swollen, blisters, then scabs; falls off in 1-3 weeks • Minimal scarring – Indications • Genital warts • Seborrheic keratosis • Actinic keratosis
  • 29. Malignant Melanoma • 1/3 of all melanoma occur in existing nevi or moles – Any sudden or progressive change in size, color or shape of a mole should be checked
  • 30. Malignant Melanoma • Can metastasize anywhere • Most deadly of skin cancers • Causes – UV radiation – Skin sensitivity – Genetic – Hormonal – Sun exposure – Mutation of gene (B-RAF) 70%
  • 31. A B C D’s of Melanoma Asymmetry Border irregular, edges ragged Color varied pigmentation • Tan, brown, black, red Diameter > 6mm
  • 32. Melanoma Medical Tx Depends on site, stage, age and general health of client – Surgery – Chemotherapy – Biologic Therapy • Interferon, interleukin – Radiation therapy
  • 33. Prevention/Education • Sunscreen • Limit exposure • Hat/clothes/sunglasses • Shade • Inspect skin regularly
  • 34. Sunburn: Education (Protect, Protect, Protect) • Same precautions as for skin cancer. • Don’t let clouds or cool air fool you – Florida sun is damaging then too. • Get out of the sun before you turn red! • Cool skin off. Immediately! • Hydrate!
  • 35. Sunburn • Superficial burn • Excessive exposure to ultraviolet rays injures dermis. • Dilated capillaries = red, tender, edema, blisters • Large area = nausea, fever
  • 36. Sunburn • Redness & pain begin within a few Hours. • Intensity may increase before subsiding. • 3-5 days to heal • Tx: cool bath; soothing lotions; topical corticosteroids; fluids
  • 37. Insects/Pests/Parasites • Spiders • Fire Ants • Lice/Scabies • Mosquitoes • Scorpions • “Sand fleas”
  • 38. Infestations: Pediculosis – Head, body or pubic lice (“crabs”) – Parasite excrement and eggs on skin – Nits in hair • Waxy, don’t fall off easily • Symptoms • Tiny red points to papular wheal-like lesions • Pruritis – check hairline • Secondary excoriation
  • 39. Pediculosis Medical tx • Pyrethrins (Rid), Permethrin (Nix) or if all other agents fail…Benzene hexachloride (Kwell) • Contact screening • l
  • 40. Infestations: Scabies – Skin reactions due to eggs, feces, & mite parts – Transmitted by direct contact • Symptoms – Severe itching especially at HS – Usually not on face – Presence of burrows esp. interdigital webs & flexor surface of wrists – Redness, swelling, vesiculation
  • 41. Scabies Medical tx – Topical Scabicide – Antibiotics for 2ndary infection – Treat those in close proximity – Clothing & linens – hot water and detergent
  • 42. Drug Therapy: Antiparasitics – Pediculicides • Pyrethrins (RID) • Permethrin (NIX) – Scabicide & Pediculicide • Lindane (Kwell, Scabene) – Cream, lotion – Shampoo  nit comb – Adverse effects  Rash, rare CNS toxicity
  • 43. Plants in FL that irritate skin • Poinsettia, Croton • Milky sap can cause skin irritation • Oleander – Touching the plant is not dangerous, but prolonged contact can irritate the skin. • Poison Ivy , Brazilian Pepper – Touching the leaves or oil from the plant can cause an itchy rash with blisters.
  • 46. Drug Therapy • Topical Corticosteroids – Anti-inflammatory, antipruritic • Low potency (hydrocortisone) – Slower acting – Can be used longer without serious side effects – Ointment most efficient – Higher potency, long term, systemic use is different tx
  • 47. – Intralesional • Reservoir of med effects lasts several weeks to months • Indications – Psoriasis – Alopecia – Cystic acne – Hypertrophic scars and keloids – Systemic • Undesirable adverse effects – Lilley 6th ed. Page 869 • Short term therapy – poison ivy • Long term therapy – chronic bullous diseases Corticosteroids Triamcinolone (Kenalog)
  • 48. Bases for Topical Medications • Powder – Promotes dryness – Good for antifungals • Lotion – Cooling and drying with residual powder film – Good for pruritic eruptions • Cream – Emulsion of oil and water – Lubrication and protections • Ointment – Oil with water in suspension – Lubrication – Most efficient delivery system • Paste – Mixture of powder and ointment – Drying – Moisture absorption
  • 49. Nursing Management: RN as skin “symptomologist” • Dry skin – Elderly; Infants • Itchy skin • Broken skin • Prevention of secondary infections
  • 50. Nursing Management: Dry skin • Manifestations • Interventions: – Elder – • Fewer total baths • Lotions & Mild soaps • Hydrate!
  • 51. Nursing Management: Itchy skin • Control of pruritis – Keep cool – No rubbing – Moisturize – Systemic antihistamines – Wet dressing – Topical steroids – Menthol, Camphor, Phenol numb itch receptors – Oatmeal baths
  • 52. Nursing Management: itch • Baths – For large body areas – Has sedating and antipruritic effect – Oilated oatmeal (Aveeno), potassium permangenate, sodium bicarb – Temp comfortable to client – Soak 15-20 mins 3-4 times daily – Pat dry, no rubbing – apply moisturizers or meds after baths
  • 53. Nursing Management • Wet dressings – Indications • Skin weepy from infection/inflammation • Relieves itching • Debrides wound • Increases penetration of topical meds • Relieves discomfort • Enhances removal of scabs, crusts, and exudate
  • 54. Wet dressings Procedure •Clean solution and gauze •Squeeze until not dripping •Apply to affected area, avoid normal tissue •Leave in place 10-30 minutes 2-4 times a day •Discontinue if skin macerates (“to soften”)
  • 55. Nursing Management: Protect • Protect intact skin! – Turn at least q2h – Reposition frequently – Alleviate pressure – Hydration – Mechanical intervention – Rx
  • 56. Nursing Management: Psychological support • Chronic skin conditions – Emotional stress – Self concept alterations – Body image changes
  • 57. Nursing Interventions: Psychological support: – Support client – Allow verbalizations of frustrations – Reinforce treatment – Support groups – Help with camouflage
  • 58. Diagnostic Testing Biopsy – Punch – Incisional – Excisional – Shave RN Responsibilities – Informed Consent – Prep site – Assist with procedure – Apply dressing – Post-op instructions – Properly ID specimen
  • 59. Diagnostic Testing • Cultures – Diagnose fungal, bacteria, viral infections – KOH (Potassium Hydroxide) • Fungus • Sample collection – Skin scraping – Swabbing – Meticulous labeling
  • 60. Diagnostic Testing • Woods Light – Organisms fluoresce • Pseudomonas • Fungus • Vitiligo • Mineral oil slides – Infestations • Patch test – Allergen testing
  • 61. Dermatological Interventions • Phototherapy – UVA & UVB (UVL) – Ultraviolet wavelengths cause erythema, desquamation, and pigmentation – Enhance with psoralem (photosensitizing) • Treatment for • Psoriasis • Atopic dermatitis • Vitiligo
  • 62. Phototherapy • Adverse effects – Basal or squamous cell Ca – Burns – Erythema – Teach patients to avoid further sun exposure & photosensitizing drugs – Wear eye protections as psoralem absorbed by lens of eye
  • 63. Dermatological Interventions • Radiation Therapy – Indications • Cutaneous malignancies – Advantages • Produces minimal damage to surrounding tissues – Adverse effects • Permanent hair loss (alopecia) to irradiated areas • Telangiectasia • Atrophy • Hyperpigmentation / depigmentation • Ulceration • BCC and SCC y.
  • 64. Dermatological Interventions • Laser Therapy (CO2, Argon) – Cuts, coagulates, & vaporizes tissue – No cumulative tissue damage • Indications – Coagulation of vascular lesions – Skin resurfacing – Removal birthmarks – BCC – Keloids – Plantar warts
  • 65. Diagnostic & Surgical Therapy • Skin Scraping – Scalpel – Surface cells for microscopic inspection • Electrodesication & electrocoagulation – Electrical energy converted to heat – Destroys tissue by burning • Coagulates bleeding vessels • Curettage – Remove tissue with circular cutting edge – Small skin tumors • warts, seborrheic keratosis, BCC, SCC
  • 66. Allergic Conditions • Contact Dermatitis – Delayed hypersensitivity – Lesions 2-7 days after antigen exposure • Manifestations – Red, hive-like papules and plaques – Sharply circumscribed – Vesicles – Pruritic
  • 67. Contact Dermatitis Medical Tx – Topical corticosteroids – Antihistamines – Skin lubrication – Elimination of allergen – Systemic steroids if severe http://dermatology.cdlib.org/DOJvol7num1/NYUcases/contact/joe.html
  • 68. Drug Therapy: Antihistamines • Compete with histamine receptor site – Oral or Topical • Cetitizine (Zyrtec) – PO tabs, syrup QD – Non-sedating • Diphenahydramine (Benadryl) – PO, IM, topical • Indications – Urticaria – Pruritis – Allergic reactions
  • 69. Drug Therapy: Antihistamines • Adverse effects – Anticholinergic – Sedation (Benadryl) – Use with caution in older adults • Indications – Urticaria – Pruritis – Allergic reactions • Adverse effects – Anticholinergic – Sedation (Benadryl) – Use with caution in older adults
  • 70. Allergic Conditions: Drug Reaction • Manifestations – Rash of any morphology – Red, macular, papular – Generalized rash with sudden onset – Pruritic – Can occur as late as 14 days after drug is stopped
  • 71. Drug Reaction Medical Treatment – Discontinue drug – Antihistamines, local or systemic – Corticosteroids if needed
  • 72. Allergic Conditions: Atopic Dermatitis – Cause unknown – Begins in infancy and declines with age • Manifestations – Scaly, red to re-brown, circumscribed lesions – Pruritic – Symmetric eruptions
  • 73. Atopic Dermatitis – Topical corticosteroids – Phototherapy – Coal tar corticosteroids – Lubrication of dry skin – Antibiotics for secondary infections Medical Treatment
  • 74. Dysplastic Nevus Syndrome • Abnormal mole pattern • Increased risk for melanoma – Doubles with dysplastic nevi • Atypical moles larger than usual (>5mm) • Irregular borders, possibly notched • Various variegated colors • Most common on back
  • 75. Infections of the skin • Risk factors – Imbalance between host and microorganism – Broken or damaged skin; Trauma – Systemic disease such as Diabetes – Moisture – Obesity – Systemic corticosteroids, antibiotics • Prevention – Proper hygiene – Good health
  • 76. Infections: Herpes Simplex Virus, Type I (AKA “cold sores/fever blisters”) • Contagious • Dormant – Exacerbation • Triggers • Symptoms -- 1st episode 3-7 days after exposure – Painful local reaction – Vesicles on erythematous base – Fever, malaise
  • 77. Herpes Simplex Virus, Type I Medical Tx – Symptom management – Moist compresses – Petrolatum to lesions – Antiviral agents (Zovirax, Famvir, Valtrex) www.treatmentsforhealth.com/.../cold-sores/
  • 78. Infections: Herpes Simplex Virus, Type II – Genital “Most genital herpes is caused by HSV-2.” (n.l.m.-n.i.h./ Medline plus) – Recurrence more common than oral • Does not mean re-infection • Symptoms – Same as Type I • Treatment – Same as Type I Iggy page 1742-1743
  • 79. Infections: Herpes Varicella Virus (chicken pox) ** Highly contagious • No chicken pox or vaccination • Keep those w/active lesions separated until crusted • Symptoms – Vesicular lesions in successive crops • Face , scalp, spreading to trunk and extremities  Protect eyes  Do not squeeze pustules or crusts • Vesicles > pustules > crusts > scars • Postherpetic neuralgia • Self limiting in children
  • 80. Herpes Varicella Virus Medical Tx – Antivirals – Symptomatic relief
  • 81. Infections: Herpes Zoster (shingles) – Activation of varicella zoster virus – Frequent occurrence in immunocompromised – Potentially contagious to immunocompromised • Symptoms – Linear patches along dermatome – Grouped vesicles on erythematous base – Unilateral on trunk – Burning pain and neuralgia
  • 82. Herpes Zoster Medical Tx – Symptomatic • Wet compresses • White petrolatum to lesions – Antiviral agents
  • 83. Drug Therapy: Antivirals – Acyclovir (Zovirax) • Suppresses chicken pox, herpes simplex 1 & 2, shingles • Po, IV, topical – Valacyclovir (Valtrex) • Herpes zoster (shingles) & genital herpes – Vaccines • Varivax – Prevention of chicken pox – Given to children > 12 mo. • Zostivax – HZU vaccine for adults > 60 y/o
  • 84. Infections: Verruca Vulgaris – Human papillomavirus – Mildly contagious • Symptoms – Circumscribed hypertrophic flesh colored papule • Treatment – Scoop removal – Liquid nitrogen therapy – Keratolytic agents – CO2 laser therapy
  • 85. Infections: Plantar Warts (Human papillomavirus) • Symptoms – Wart on “Plantar” surface (bottom) of foot – – Cone shaped with black dots (“seeds”)
  • 86. Plantar Warts Medical Tx – Liquid nitrogen – Frequent paring with chemical patches – Duct tape??????
  • 87. Infections: Candidiasis (moniliasis) – Candida albicans (Fungus) – 50% are symptom free carriers – Immunocompromised >> pathogenic – Likes warm moist areas • Mouth, vagina, skin An opportunistic infection
  • 88. Infections: Candidiasis – Symptoms • Mouth – White, cheesy plaque (milk curds) • Vagina – Vaginitis – Red edematous painful vaginal wall – White patches – Vaginal discharge – Pruritis – Painful urination & intercourse • Skin – Diffuse papular erythematous rash – Pinpoint satellite lesions around edges Physiologic Integrity: 5. Discuss nursing implications for medications prescribed for clients with dermatologic disorders. 6. Develop plan of care for client with impaired skin integrity.
  • 89. Candidiasis Medical Tx: Anti-fungals • Nystatin – Vaginal suppository – Oral lozenge • Mycostatin powder, cream • Keep skin clean dry • Diagnosis culture Microscopic exam (KOH)
  • 90. Infections: Fungal • Tinea Corporis – AKA ringworm – Symptoms • Annular • well defined margins • erythematous
  • 91. Tinea Corporis AKA ringworm Medical Tx •Cool compresses •Topical antifungals – Miconazole, clotrimazole, butenafine
  • 92. Infections: Fungal • Tinea Cruris – AKA jock itch – Symptoms • Self-defined border • In groin – Treatment topical antifungal cream or solution
  • 93. Infections: Fungal • Tinea Pedis – AKA athletes foot – Symptoms • Interdigital scaling • Erythema • Blistering • Pruritis • Pain
  • 94. Medical Tx • Topical antifungals • Keep dry Tinea Pedis AKA athletes foot
  • 95. Infections: Fungal • Tinea Unguium – Symptoms • Brittle thickened nails • White/yellow discoloration
  • 96. Tinea Unguium Medical Tx • Topical antifungal cream or solutions • Griseofulvin (fingernails) • Lamisil • Debride toenails
  • 97. Drug Therapy: Antifungals – Clotrimazole (Mycelex, Lotrimin) • Lozenges- thrush • Cream, solution, lotion- athletes foot • Intravaginal creams, tablets – Miconazole (Monistat, Micotin) • Athletes foot • Jock itch • Ringworm • Yeast infections
  • 98. Drug Therapy: Antifungals – Fluconazole (Diflucan) • PO & IV • Excellent bioavailability • Vaginal or systemic candidiasis – Ketaconazole (Nizoral) – Nystatin (Mycostatin) – Tervinafine (Lamisil) for onychomycosis – Tolnaftate (Tinactin)
  • 99. Infections, Bacterial • Impetigo – Group A beta hemolytic strept or staph – Associated with poor hygiene and low socioeconomic status • Symptoms – Vesiculopustular lesions – Thick honey colored crust – Surrounded by erythema – Pruritic – Contagious • Treatment – Systemic antibiotics – Saline or aluminum acetate soaks – Soap & water – Removal of crusts – Topical antibiotic cream • Strept can cause glonerulonephritis if untreated
  • 100. Infections: Bacterial • Cellulitis – Staph aureus or strept – Can be primary or secondary infection – Symptoms • Hot • Tender • Erythematous • Edematous • Diffuse borders maybe malaise and fever – Treatment • Moist heat • Immobilization • Elevation • Systemic antibiotics • Hospitalize if severe – Can progress to gangrene if untreated
  • 101. Drug Therapy: Antibiotics – Topical - apply lightly • OTC – bacitracin – Polymixin B • Prescription – Mupirocin (staph) – gentamycin (staph), – erythromycin (staph & strept) – clindamycin (Cleocin) (acne) – Systemic - culture & sensitivity guides selection • Penicillin • Erythromycin • Tetracycline
  • 102. Benign Skin Conditions: Acne Inflammatory disorder of sebaceous glands • Symptoms comedones, inflammatory lesions, papules, pustules face, neck, upper back • Treatment – Comedo extraction – Topical Benzoyl Peroxide – Peeling and irritating agents (retinoic acid) – Antibiotic therapy - long term – Phototherapy – Sun exposure – If severe - isotretinoin (Accutane) CAUTION! Teratogenic
  • 103. Drug Therapy: Acne Preparations – Benzoyl peroxide (Benzac, Desquam-X, PanOxyl, etc) • Apply 1-4x day • Effects seen 4-6 weeks • Adverse effects – Erythema, tenderness, dryness, pruritis, burning – Erythromycin (Eryderm, T-Stat, Erygel) • Macrolide antibiotic • Adverse effects – Erythema, tenderness, pruritis, burning
  • 104. Drug Therapy: Acne Preparations – Isotretinoin (Accutane) • Pregnancy Category X – Proven teratogen – 2 contraceptive methods – Tretinoin (Retinoic acid, Vitamin A acid, Retin-A) • Stimulates epidermal cell turnover -> skin peeling • Adverse effects – Red edematous blisters, crusted skin, altered skin pigmentation • Avoid sun, use sunscreen • Apply to dry skin
  • 105. Benign Skin Conditions: Moles Grouping of normal cells • Manifestations – Hyperpigmented areas – Varying form and color • Treatment – None necessary – Cosmetic – Biopsy for diagnosis
  • 106. Benign Skin Conditions • Psoriasis – Chronic dermatitis due to rapid turnover of epidermal cells – Family predisposition – Manifestations – Sharply demarcated scaling plaques of • Scalp • Elbows • Knees • Palms, soles, and fingernails possible • Treatment – Retard growth of epidermal cells – Topical corticosteroids – Tar – Anthralin topical – Sunlight, UV light – Alefacept (Amevive) injection – Antimetabolites (methotrexate) or systemic retinoids for difficult cases
  • 107. Benign Skin Conditions • Seborrheic Keratoses – Irregularly shaped flat topped papules or plaques – Warty surface – Appearance of being stuck on – Increase in pigmentation – No association with sun exposure – Treatment • Removal – Curettage – cryosurgery
  • 108. Benign Skin Conditions: Lipoma Encapsulated tumor of adipose tissue Most common 40-60 years of age • Manifestations – Rubbery, compressible, round mass – Variable in size – Most common on trunk, back of neck, forearms • Treatment – Biopsy – Excision if indicated
  • 109. Benign Skin Conditions: Vitiligo – Unknown cause – Genetic connection – Complete absence of melanocytes – Non-contagious • Manifestations – Complete loss of pigment – Variation in size an location – Symmetric and permanent • Treatment – Exposure to UVA and psoralens – Depigmentation of pigmented skin in extensive disease – Cosmetics and stains
  • 110. Benign Skin Conditions: Lentigo • (see fig. 26-7, Iggy page 465) – AKA liver spots – Increased number of melanocytes – Related to aging and sun exposure • Manifestations – Hyperpigmented brown to black flat lesion – Usually in sun exposed areas • Treatment – Liquid nitrogen • Possible reoccurrence in 1-2 years – Cosmetics
  • 111. Primary Lesions • Macule (freckles, petecchia, measles) – Flat – Change in color – < 1cm • Papule (wart, mole) – elevated, – Solid – <1cm • Vesicle (chicken pox, herpes zoster, 2nd burns) – Elevated – Fluid filled – <1cm
  • 112. Primary Lesions • Bulla – > 1cm – Elevated – Serous fluid filled • Plaque (psoriasis, keratosis) – Elevated – Solid lesion – >1cm
  • 113. Primary Lesions • Wheal (insect bite) – Firm – Edematous – Irregular shape – Diameter variable • Pustule (acne, impetigo) – Elevated – Purulent fluid – Varied size
  • 114. Secondary Lesions • Fissure (athletes foot) – Linear crack from epidermis to dermis • Scale (excess dead & flaking of skin) – Drug eruption – Scarlet fever • Scar – Increased connective tissue – Surgical incision – Healed wound
  • 115. Secondary Lesions • Ulcer – Crater – Loss of epidermis, dermis – Pressure ulcers, chancre • Atrophy – Thinning of epidermis/dermis – Ages skin, striae • Excoriation – Missing epidermis – Scabies, abrasion, scratch
  • 116. References: • Chickenpox in Pregnancy. (2009). March of Dimes Foundation. Retrieved 9/25/09 from http://www.marchofdimes.com/professionals/14332_1185.asp • Common Poisonous Plants of Florida (Florida Poison Information Center/Tampa) @ http://www.poisoncentertampa.org/poisonous-plants.aspx • Culbert, D. (April 14, 2005). Florida scorpions. UF/IFAS Okeechobee County Extension Service. Retrieved 6/17/09 from http://okeechobee.ifas.ufl.edu/News%20columns/Florida.Scorpions.htm • Groch, J. (August 23, 2006). Guidelines for Preventing Pressure Ulcers Seen as Suboptimal. MedPage Today. Retrieved 6/12/09 from http://www.medpagetoday.com/Dermatology/GeneralDermatology/3982
  • 117. References: • Hembree, D. (July 21, 2008) 10 Poisonous Plants in Florida and Safety Precautions @ http://www.associatedcontent.com/article/875395/10_poisonous_pla nts_in_florida_and_pg2.html?cat=11 • “Herpes simplex” (May, 2009). Medline Plus Medical Encyclopedia. Retrieved 6/15/09 from http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/001324.htm • Lilly, L.L., Harrington, S, & Snyder, J. (2005) Pharmacology and the Nursing Process. (4th ed.) Mosby Elsevier. St. Louis, MS. • Medical Dictionary (2009) Merrium – Webster Inc. Retrieved 6/15/09 from http://www.nlm.nih.gov/medlineplus/mplusdictionary.html
  • 118. References: • The Medical News. Brain eating amoeba in lake kills sixth victim. (October 2007). Retrieved 6/16/09 from http://www.news- medical.net/news/2007/10/07/30863.aspx • The US Market for Skin Care Products. (May, 2005). Retrieved 6/12/09 from http://www.mindbranch.com/Skincare-Products-R567- 0199/ • Scorpion Sting Treatments. (2008). Orkin. Retrieved 6/17/09 from http://www.orkin.com/other/scorpions/scorpion-sting-treatments
  • 119. Burns • Thermal burns – Flame, flash, scald • Chemical burns – Necrotizing substances • Acids • Alkali – Cleaning agents, drain cleaners, lye • Electrical burns – Intense heat from electrical current The Following Content – Burns – will be covered in future classes! Save this information for future use.
  • 120. Classification: Depth of Burn See page 522 in Iggy text • ABA by depth of destruction – Partial thickness burn • Epidermis and dermis involved – Full thickness burn • “burns reach through the entire dermis and sometimes into the subcutaneous fat.” (Iggy, page 522) • Possibly involves muscles, tendons, and bones • *Skin cannot heal on its own.
  • 121. Classification: Extent of Burn • Total Body Surface Area (TBSF) – (Iggy page 531) • Berkow method – http://www.umobile.edu/main/notes/Burn.pdf • Rule of 9’s – (Iggy page 531)
  • 122. Classification: Location of Burns • Severity related to location • Complication risks related to location • Face, neck, chest – Respiratory complications • Hands, feet, joints, and eyes – Compromise ADLs • Circumferential burns of extremities – Circulatory compromise
  • 123. Emergent Care • A,B,C’s • Fluid Therapy • Wound Care • Pain management • Prevention of infection
  • 125. Complications of Emergent Phase • Cardiovascular – Arrhythmias – Hypovolemic shock – Impaired circulation • Respiratory – Upper airway burns – Inhalation injuries • Urinary – Acute tubular necrosis
  • 126. Acute Phase • Fluid therapy – Lactated Ringers per Parkland (Baxter) formula • Wound care – Topical silvadene, sulfamylon, bacitracin, or bactroban – PREVENT INFECTION • Excision and grafting – Remove necrotic tissue – Apply split thickness auto graft skin • Porcine skin, cadaver skin, clients own skin, skin culture • Nutritional therapy – Increased fluids, proteins, vitamins A, C, E. – Zinc, iron, folate • Physical therapy – Prevent contractures • Physical and psychological comfort
  • 127. Drug Therapy: Antibiotics • Silver Sulfadiazine (Slivadene) – Burn treatment – QD or BID – “frosting” – Adverse effects • Pain • Itching • Burning
  • 128. Rehabilitation Phase • Prevent and minimize contractures and scarring! • Cosmetic / reconstructive therapy • Psychological support if needed