This document summarizes a presentation on new approaches to food allergy testing. It begins with the presenter's commercial disclosure statements listing companies he has received honoraria from or served on speaker's bureaus for. The presentation then covers the different immunoglobulin antibodies involved in food allergies, specifically IgE, IgG, and IgA. It discusses the mechanisms and downstream effects of these antibodies and food allergy reactions. Finally, it reviews several studies that have found associations between food allergies or sensitivities and conditions like attention-deficit/hyperactivity disorder, depression, anxiety, and autism spectrum disorders.
Medical Discussion of the Endocannabinoid SystemLouis Cady, MD
This document contains a slide deck presentation on hemp oil and the endocannabinoid system. It discusses the history of research on cannabis, the endogenous cannabinoid system, and how various interventions can upregulate this system. Throughout, it stresses that the information is for educational purposes only and that no claims are being made about Zilis products treating, preventing, or curing any diseases.
Natural Treatments for ADHD (TADH) in Sao Paulo, Brazil, for Laboratorio Grea...Louis Cady, MD
In this presentation, given at UNIP (Campus Paraiso - Sao Paulo, SP Brazo) for the 2019 Congresso de Saude Mental (Conference on Mental Health), Dr. Cady reviewed the prevalence, inheritability, and social ramifications of ADHD (TADH in Brazil). He specifically reviewed multiple holistic interventions, including limiting "electric screen time,"good quality diet with adequate amounts of essential fatty acids and critically important trace elements, and the use of pharmacogenomic testing as well as functional, integrative medicine testing, all to better characterize logical and reeasonmable points for holistic intervention.
This presentation was simultaneously translated into Portugue for the attendees, but unfortunately the slides were not available in translated form.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
Thyroid, Adrenals, and Sex Steroids - A Balancing ActLouis Cady, MD
This was the second presentation gibven on MZarch 29, 2019 at the Manlove Psychiagtric Group and Brain Injury Institute spring conference in Rapid City, SD.
In this presentation, Dr. Cady carefully goes over the necessity of integrating and overview and awareness of hormones and their levels in the elucidation of what truly is going on with the patient.
This was an overview lecture only. Dr. Cady will be presenting a 16 hour CME program in Austin Texas on June 22 and 23 for the National Procedures Institute, and will explore all aspects of all relevant hormones and what can be done to manage and optimize them.
Hemp Oil: What Can It Do For You? Lebanon, TN 04 06 2018Louis Cady, MD
In this presentation, Dr. Cady reviews the peer-reviewed medical literature for the endocannibinoid system, the concept of endocannibinoid deficiency syndrome (now well established), and citations dealing with the multiplicity of health conditions for which a full spectrum hemp oil should be considered as a reasonable supportive strategy. The difference between the generic "CBD Oil" that is available at health food stores compared to the Zilis products is touched on. The Zilis products appear to have better absorbability, faster onset of action, and scientific studies elucidating the true duration of action of CBD levels in blood serum.
This presentation was given to a very appreciative audience at the Friendship Church in Lebanon, TN (a suburb of Nashville).
The Do It To Yourself Treatment of Depression - Webinar #3Louis Cady, MD
This is the third in a series of five webinars. The first was on staying alive by boosting your immunity during COVID 19. The second was on not screwing yourself up inside your head. This third one encompasses a romp through the peer reviewed medical literature looking for supplements and nutrients that you could use to self treat depression at home, CAREFULLY. Numerous cautions and warnings are included.
The driving impetus to this program is that many people - due to social isolation and their mental health care, or medical practitioners' offices being closed down - have not been able to get help or succeed in optimizing their treatment for depression. There are multiple useful nutrients for both depression and anxiety in nature's abundant pharmacopeia, and this webinar touches on just a few of them.
I hope you enjoy it.
The integrative treatment of schizophrenia brazil 2019Louis Cady, MD
This is the English language version of Dr. Cady's presentation given at UNIP (Campus Paraiso - Sao Paulo, SP Brazil) for the 2019 Congresso de Saude Mental (Conference on Mental Health). It was delivered April 20, 2019.
This presentation also includes extra slides in the appendix that were not presented, and, unfortunately, these slides of the appendix have not been translated in the Portuguse version of this presentation.
In this presentation (Portuguese presentation will also be posted next), Dr. Cady briefly reviews the history of schizophrenia, the failure of the dopamine D2 receptor blockage as a universal cure-all in schizophrenia, and various holistic interventions which can strongly and positively impact symptoms of schizophrenia. Included in Dr. Cady's survey were the role of essential fatty acids, nutrient deficiencies (particularly B vitamins), the danger of overgrowth of candida , pharmacogenomic testing, MTHFR polymorphisms, and more.
It was an honor and a privilege to deliver this presentation in
São Paulo,.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
The document discusses molecular allergy testing for peanut allergies. It begins with an introduction of the speakers and agenda. It then provides biographies of Dr. Maeve O'Connor and Dr. Rob Reinhardt, who will discuss the physician and science perspectives on molecular allergy testing. The objectives are to raise awareness of molecular allergy testing and its role in diagnosing and managing peanut allergies. Dr. O'Connor then presents on the burden of peanut allergies and limitations of traditional testing. Dr. Reinhardt discusses the science behind molecular testing and peanut components. Case studies demonstrate how component testing provides more accurate risk assessments to guide patient management decisions.
This document discusses the prevalence of food allergies in Southeast Asia based on a presentation by Dr. BW Lee from the National University of Singapore. It provides data on the prevalence of various food allergies like peanut allergy from studies in countries in the region. It notes that food allergy patterns may be related to environmental allergens through cross-reactivity. It also presents several case studies of allergic reactions triggered by novel allergens like prebiotics in cow's milk formula and discusses mechanisms of carbohydrate allergen epitopes.
Medical Discussion of the Endocannabinoid SystemLouis Cady, MD
This document contains a slide deck presentation on hemp oil and the endocannabinoid system. It discusses the history of research on cannabis, the endogenous cannabinoid system, and how various interventions can upregulate this system. Throughout, it stresses that the information is for educational purposes only and that no claims are being made about Zilis products treating, preventing, or curing any diseases.
Natural Treatments for ADHD (TADH) in Sao Paulo, Brazil, for Laboratorio Grea...Louis Cady, MD
In this presentation, given at UNIP (Campus Paraiso - Sao Paulo, SP Brazo) for the 2019 Congresso de Saude Mental (Conference on Mental Health), Dr. Cady reviewed the prevalence, inheritability, and social ramifications of ADHD (TADH in Brazil). He specifically reviewed multiple holistic interventions, including limiting "electric screen time,"good quality diet with adequate amounts of essential fatty acids and critically important trace elements, and the use of pharmacogenomic testing as well as functional, integrative medicine testing, all to better characterize logical and reeasonmable points for holistic intervention.
This presentation was simultaneously translated into Portugue for the attendees, but unfortunately the slides were not available in translated form.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
Thyroid, Adrenals, and Sex Steroids - A Balancing ActLouis Cady, MD
This was the second presentation gibven on MZarch 29, 2019 at the Manlove Psychiagtric Group and Brain Injury Institute spring conference in Rapid City, SD.
In this presentation, Dr. Cady carefully goes over the necessity of integrating and overview and awareness of hormones and their levels in the elucidation of what truly is going on with the patient.
This was an overview lecture only. Dr. Cady will be presenting a 16 hour CME program in Austin Texas on June 22 and 23 for the National Procedures Institute, and will explore all aspects of all relevant hormones and what can be done to manage and optimize them.
Hemp Oil: What Can It Do For You? Lebanon, TN 04 06 2018Louis Cady, MD
In this presentation, Dr. Cady reviews the peer-reviewed medical literature for the endocannibinoid system, the concept of endocannibinoid deficiency syndrome (now well established), and citations dealing with the multiplicity of health conditions for which a full spectrum hemp oil should be considered as a reasonable supportive strategy. The difference between the generic "CBD Oil" that is available at health food stores compared to the Zilis products is touched on. The Zilis products appear to have better absorbability, faster onset of action, and scientific studies elucidating the true duration of action of CBD levels in blood serum.
This presentation was given to a very appreciative audience at the Friendship Church in Lebanon, TN (a suburb of Nashville).
The Do It To Yourself Treatment of Depression - Webinar #3Louis Cady, MD
This is the third in a series of five webinars. The first was on staying alive by boosting your immunity during COVID 19. The second was on not screwing yourself up inside your head. This third one encompasses a romp through the peer reviewed medical literature looking for supplements and nutrients that you could use to self treat depression at home, CAREFULLY. Numerous cautions and warnings are included.
The driving impetus to this program is that many people - due to social isolation and their mental health care, or medical practitioners' offices being closed down - have not been able to get help or succeed in optimizing their treatment for depression. There are multiple useful nutrients for both depression and anxiety in nature's abundant pharmacopeia, and this webinar touches on just a few of them.
I hope you enjoy it.
The integrative treatment of schizophrenia brazil 2019Louis Cady, MD
This is the English language version of Dr. Cady's presentation given at UNIP (Campus Paraiso - Sao Paulo, SP Brazil) for the 2019 Congresso de Saude Mental (Conference on Mental Health). It was delivered April 20, 2019.
This presentation also includes extra slides in the appendix that were not presented, and, unfortunately, these slides of the appendix have not been translated in the Portuguse version of this presentation.
In this presentation (Portuguese presentation will also be posted next), Dr. Cady briefly reviews the history of schizophrenia, the failure of the dopamine D2 receptor blockage as a universal cure-all in schizophrenia, and various holistic interventions which can strongly and positively impact symptoms of schizophrenia. Included in Dr. Cady's survey were the role of essential fatty acids, nutrient deficiencies (particularly B vitamins), the danger of overgrowth of candida , pharmacogenomic testing, MTHFR polymorphisms, and more.
It was an honor and a privilege to deliver this presentation in
São Paulo,.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
The document discusses molecular allergy testing for peanut allergies. It begins with an introduction of the speakers and agenda. It then provides biographies of Dr. Maeve O'Connor and Dr. Rob Reinhardt, who will discuss the physician and science perspectives on molecular allergy testing. The objectives are to raise awareness of molecular allergy testing and its role in diagnosing and managing peanut allergies. Dr. O'Connor then presents on the burden of peanut allergies and limitations of traditional testing. Dr. Reinhardt discusses the science behind molecular testing and peanut components. Case studies demonstrate how component testing provides more accurate risk assessments to guide patient management decisions.
This document discusses the prevalence of food allergies in Southeast Asia based on a presentation by Dr. BW Lee from the National University of Singapore. It provides data on the prevalence of various food allergies like peanut allergy from studies in countries in the region. It notes that food allergy patterns may be related to environmental allergens through cross-reactivity. It also presents several case studies of allergic reactions triggered by novel allergens like prebiotics in cow's milk formula and discusses mechanisms of carbohydrate allergen epitopes.
How to Transition from Allopathic to Integrated Practice - IMM Brazil 2015Louis Cady, MD
In this lecture, Dr. Cady compares and contrasts the significance differences, both conceptually and practically, between the conventional practice of medicine and a more rational, functional, integrated approach. Tactical concepts and didactic tools to make the transition are reviewed.
Join Us! Professor Ruby Pawankar, President of the World Allergy Organization (WAO), and Professor Motohiro Ebisawa, Chair of the WAO Communications Council, warmly welcome WAO Member Societies to World Allergy Week 2013 (8-14 April). This year’s theme is “Food Allergy—A Rising Global Health Problem”, and there are many ways Member Societies can participate to help highlight food allergies, provide information about the their increasing prevalence, and explain the need for enhanced education and patient care services to improve safey, prevention, and quality of life.
WAO will again provide resources for its member societies to use for local activities.
THE ENDOCANNABINOID SYSTEM - Cady Wellness InstituteLouis Cady, MD
This lecture, presented on February 2, 2018 at the Cady Wellness Institute in Newburgh, IN, represented Dr. Cady's review of the current peer-reviewed medical literature current as of that morning. The concepts of "endocannabinoids" vs. "phytocannabinoids" were reviewed. Themes in the medical literature were explored, including the relationship of the endocannabinoid system and CB! and CB2 receptors to modulate hippocampal neurogenesis, cause apoptosis in breast cancer cells, and many other interesting correlations. A careful review of legal vs illegal options for obtaining plant phytocannabinoids in the state of Indiana was emphasized.
What is new in general pediatrics, allergic and respiratory diseasesEnvicon Medical Srl
The document discusses several studies related to general pediatrics, allergic and respiratory diseases from 2017.
One study found that early-term deliveries between 37-38 weeks gestation were associated with increased risk of long-term respiratory morbidity compared to full-term deliveries between 39-40 weeks. Another study showed that preschoolers with bedtimes before 8pm had a lower risk of adolescent obesity than those with later bedtimes. A third study found that high school start times later than 8:30am were associated with improved attendance and graduation rates.
The document summarizes an international collaboration between four allergy organizations to develop consensus guidelines on food allergy. An author group was formed and divided into committees to write sections on the definition of food allergy, epidemiology, diagnosis, and treatment. Food allergy is defined as an adverse immune response to a food, which can be IgE-mediated, non-IgE mediated, or both. IgE-mediated reactions typically cause acute symptoms within 2 hours of exposure. While many foods can cause allergies, a minority cause most reactions and common allergens vary by region. Treatment involves avoidance of trigger foods and medications to manage symptoms, as there is currently no cure.
Prof. Dr. Vladimir Trajkovski-Etiology and pathogenesis of ASDVladimir Trajkovski
These are slides from webinar which Prof. Dr. Vladimir Trajkovski held for colleagues from India. The title of lecture is Etiology and pathogenesis of autism spectrum disorders. Webionar was on YouTube channel in live od 23.05.2018.
Natural Treatments for ADHD - December 7th, 2016 - Saint Marys HospitalLouis Cady, MD
This lecture, presented December 7th, 2016 for the Parent Support Group for children with ADHD and Sensory Processing Disorders, was presented at Saint Marys Hospital in Evansville, Indiana. In this one hour presentation, Dr. Cady broke down some of the alternative treatments for ADHD, grounded in the peer-reviewed literature, that do not involve the prescription of typical psychiatric medication for ADHD. He emphasized, natural, holistic treatments to treat deficiencies and restore balance of nutrients and specific essential fatty acids.
The presentation is regarding treatment and is not a study; it is a collection of observations made during the treatment of patients. The presentation covers food allergy management strategies, psychological and social impact of food allergy, risk management, food allergen desensitization treatment, and OIT treatment findings.
Presentation By: Dr Richard L Wasserman of Dallas Allergy Immunology
This document summarizes an article from the Winter 2013 issue of SCAN's Pulse about working with patients who have dietary restrictions related to food allergies in the treatment of eating disorders. The summary includes:
1) It is important for dietitians treating eating disorders to understand the difference between true food allergies diagnosed by validated tests and perceived or self-reported food intolerances in order to avoid exacerbating disordered eating behaviors.
2) Common validated diagnostic tests for food allergies include skin prick tests, radioallergosorbent tests, and double-blind placebo-controlled food challenges, while alternative tests lack scientific evidence.
3) Patients with eating disorders may perceive food
Oral immunotherapy using egg powder was studied to induce desensitization in children with egg allergy. Children received daily increasing doses of egg powder or placebo for 10 months, then continued maintenance dosing. At 10 months, 67% of those receiving egg powder passed an oral food challenge compared to 2% of placebo. At 22 months, 51% passed without symptoms. Levels of egg-specific IgG4 after 10 months predicted response. Oral immunotherapy shows promise as a treatment for egg allergy but further research is still needed.
This document summarizes research from the REVEAL Study, which investigated the risks and benefits of disclosing genetic risk information for Alzheimer's disease based on APOE genotype. Key findings include:
- Those who received disclosure showed no significant short-term increases in anxiety or depression scores. Recall of risk information was generally accurate.
- Disclosure did not significantly change health behaviors or insurance purchasing in most participants. Some higher-risk individuals did increase exercise and cognitive activities.
- Most participants were satisfied with receiving their results and would undergo testing again. However, nearly half of accurate recallers still believed their risk was different.
- Condensed disclosure protocols may be as effective as more extensive counseling and
1) A study of 651 children with pollen-related allergic rhinitis found that component-resolved diagnosis identified a lack of IgE antibodies to major allergens in a significant percentage of patients with skin prick test reactivity, calling into question the appropriateness of immunotherapy for some patients.
2) Without component-resolved diagnosis, immunotherapy would have been prescribed inappropriately in 37% of cases based on skin prick test alone.
3) Component-resolved diagnosis led European and American allergists to change their immunotherapy prescription decisions in 42-48% of cases compared to skin prick testing alone.
"Killer Drugs & The Supplement Hall of Fame" - IMMH Brazil, 2015Louis Cady, MD
In this presentation, the third of three lectures Dr. Cady delivered in São Paulo, Brazil, Dr. Cady reviews the critical patterns of interactions with numerous frequently prescribed psychotropic medications (and others). Emphasis is given on how not to commit an obvious drug-drug interaction as well as avoiding more subtle ones. The focus then shifts to supplements: which ones are the best, which ones have mental health benefits, and how to avoid interactions between conventionally used supplements and psychiatric medications.
The document summarizes information from a lecture on food allergies. It discusses that food allergies affect up to 12 million Americans and are caused by an adverse immune response to food proteins. The most common food allergies are to the "Big 8" foods of dairy, eggs, peanuts, tree nuts, seafood, shellfish, soy, and wheat. Diagnosis involves tests like skin prick tests and blood tests to detect allergy-causing IgE antibodies. Treatment is complete avoidance of the offending foods. Future research aims to develop vaccines or cures for food allergies.
This paper demonstrates knowledge of the indirect connection between diet and autism-related behaviors and the anatomical reasoning behind the position. I am studying to be a pediatric occupational therapist - a career field that often has patients with developmental abnormalities that can be treated with therapy and supplemented by diet.
A diet rich in vitamins, minerals and fatty acids can help reduce aggression and improve mood. Studies in prisons found that inmates who received supplements had significantly fewer rule violations and violent incidents than those who received placebos. Similarly, studies in schools found that children who received omega-3 supplements performed better academically than those who received placebos. While more research is still needed, current evidence suggests nutrition may play an important role in mental health and behaviors.
Alergia a los almentos mediadas por anticuerpos ig g asociadas con la migraña...MEDIAGNOSTIC
This document discusses a study investigating the presence of IgG antibodies to foods in patients with migraine refractory to traditional treatment. The study found:
1) Statistical significant differences in the number of positive IgG food allergens between patients with migraine (56 patients) and a control group without migraine.
2) Elimination diets successfully controlled migraines in patients, without the need for medications.
3) According to the results, serum IgG antibodies to common foods should be investigated in patients with migraine.
What’s the latest news about MAP grants (including the MAP 2+2 pilot program), Pell grants, student loans, and funding for these programs? This session will provide an overview of the changes to state and federal financial aid programs for the 2012-13 school year, as well as provide updates on state and federal legislative, operational, and budgetary issues.
How to Transition from Allopathic to Integrated Practice - IMM Brazil 2015Louis Cady, MD
In this lecture, Dr. Cady compares and contrasts the significance differences, both conceptually and practically, between the conventional practice of medicine and a more rational, functional, integrated approach. Tactical concepts and didactic tools to make the transition are reviewed.
Join Us! Professor Ruby Pawankar, President of the World Allergy Organization (WAO), and Professor Motohiro Ebisawa, Chair of the WAO Communications Council, warmly welcome WAO Member Societies to World Allergy Week 2013 (8-14 April). This year’s theme is “Food Allergy—A Rising Global Health Problem”, and there are many ways Member Societies can participate to help highlight food allergies, provide information about the their increasing prevalence, and explain the need for enhanced education and patient care services to improve safey, prevention, and quality of life.
WAO will again provide resources for its member societies to use for local activities.
THE ENDOCANNABINOID SYSTEM - Cady Wellness InstituteLouis Cady, MD
This lecture, presented on February 2, 2018 at the Cady Wellness Institute in Newburgh, IN, represented Dr. Cady's review of the current peer-reviewed medical literature current as of that morning. The concepts of "endocannabinoids" vs. "phytocannabinoids" were reviewed. Themes in the medical literature were explored, including the relationship of the endocannabinoid system and CB! and CB2 receptors to modulate hippocampal neurogenesis, cause apoptosis in breast cancer cells, and many other interesting correlations. A careful review of legal vs illegal options for obtaining plant phytocannabinoids in the state of Indiana was emphasized.
What is new in general pediatrics, allergic and respiratory diseasesEnvicon Medical Srl
The document discusses several studies related to general pediatrics, allergic and respiratory diseases from 2017.
One study found that early-term deliveries between 37-38 weeks gestation were associated with increased risk of long-term respiratory morbidity compared to full-term deliveries between 39-40 weeks. Another study showed that preschoolers with bedtimes before 8pm had a lower risk of adolescent obesity than those with later bedtimes. A third study found that high school start times later than 8:30am were associated with improved attendance and graduation rates.
The document summarizes an international collaboration between four allergy organizations to develop consensus guidelines on food allergy. An author group was formed and divided into committees to write sections on the definition of food allergy, epidemiology, diagnosis, and treatment. Food allergy is defined as an adverse immune response to a food, which can be IgE-mediated, non-IgE mediated, or both. IgE-mediated reactions typically cause acute symptoms within 2 hours of exposure. While many foods can cause allergies, a minority cause most reactions and common allergens vary by region. Treatment involves avoidance of trigger foods and medications to manage symptoms, as there is currently no cure.
Prof. Dr. Vladimir Trajkovski-Etiology and pathogenesis of ASDVladimir Trajkovski
These are slides from webinar which Prof. Dr. Vladimir Trajkovski held for colleagues from India. The title of lecture is Etiology and pathogenesis of autism spectrum disorders. Webionar was on YouTube channel in live od 23.05.2018.
Natural Treatments for ADHD - December 7th, 2016 - Saint Marys HospitalLouis Cady, MD
This lecture, presented December 7th, 2016 for the Parent Support Group for children with ADHD and Sensory Processing Disorders, was presented at Saint Marys Hospital in Evansville, Indiana. In this one hour presentation, Dr. Cady broke down some of the alternative treatments for ADHD, grounded in the peer-reviewed literature, that do not involve the prescription of typical psychiatric medication for ADHD. He emphasized, natural, holistic treatments to treat deficiencies and restore balance of nutrients and specific essential fatty acids.
The presentation is regarding treatment and is not a study; it is a collection of observations made during the treatment of patients. The presentation covers food allergy management strategies, psychological and social impact of food allergy, risk management, food allergen desensitization treatment, and OIT treatment findings.
Presentation By: Dr Richard L Wasserman of Dallas Allergy Immunology
This document summarizes an article from the Winter 2013 issue of SCAN's Pulse about working with patients who have dietary restrictions related to food allergies in the treatment of eating disorders. The summary includes:
1) It is important for dietitians treating eating disorders to understand the difference between true food allergies diagnosed by validated tests and perceived or self-reported food intolerances in order to avoid exacerbating disordered eating behaviors.
2) Common validated diagnostic tests for food allergies include skin prick tests, radioallergosorbent tests, and double-blind placebo-controlled food challenges, while alternative tests lack scientific evidence.
3) Patients with eating disorders may perceive food
Oral immunotherapy using egg powder was studied to induce desensitization in children with egg allergy. Children received daily increasing doses of egg powder or placebo for 10 months, then continued maintenance dosing. At 10 months, 67% of those receiving egg powder passed an oral food challenge compared to 2% of placebo. At 22 months, 51% passed without symptoms. Levels of egg-specific IgG4 after 10 months predicted response. Oral immunotherapy shows promise as a treatment for egg allergy but further research is still needed.
This document summarizes research from the REVEAL Study, which investigated the risks and benefits of disclosing genetic risk information for Alzheimer's disease based on APOE genotype. Key findings include:
- Those who received disclosure showed no significant short-term increases in anxiety or depression scores. Recall of risk information was generally accurate.
- Disclosure did not significantly change health behaviors or insurance purchasing in most participants. Some higher-risk individuals did increase exercise and cognitive activities.
- Most participants were satisfied with receiving their results and would undergo testing again. However, nearly half of accurate recallers still believed their risk was different.
- Condensed disclosure protocols may be as effective as more extensive counseling and
1) A study of 651 children with pollen-related allergic rhinitis found that component-resolved diagnosis identified a lack of IgE antibodies to major allergens in a significant percentage of patients with skin prick test reactivity, calling into question the appropriateness of immunotherapy for some patients.
2) Without component-resolved diagnosis, immunotherapy would have been prescribed inappropriately in 37% of cases based on skin prick test alone.
3) Component-resolved diagnosis led European and American allergists to change their immunotherapy prescription decisions in 42-48% of cases compared to skin prick testing alone.
"Killer Drugs & The Supplement Hall of Fame" - IMMH Brazil, 2015Louis Cady, MD
In this presentation, the third of three lectures Dr. Cady delivered in São Paulo, Brazil, Dr. Cady reviews the critical patterns of interactions with numerous frequently prescribed psychotropic medications (and others). Emphasis is given on how not to commit an obvious drug-drug interaction as well as avoiding more subtle ones. The focus then shifts to supplements: which ones are the best, which ones have mental health benefits, and how to avoid interactions between conventionally used supplements and psychiatric medications.
The document summarizes information from a lecture on food allergies. It discusses that food allergies affect up to 12 million Americans and are caused by an adverse immune response to food proteins. The most common food allergies are to the "Big 8" foods of dairy, eggs, peanuts, tree nuts, seafood, shellfish, soy, and wheat. Diagnosis involves tests like skin prick tests and blood tests to detect allergy-causing IgE antibodies. Treatment is complete avoidance of the offending foods. Future research aims to develop vaccines or cures for food allergies.
This paper demonstrates knowledge of the indirect connection between diet and autism-related behaviors and the anatomical reasoning behind the position. I am studying to be a pediatric occupational therapist - a career field that often has patients with developmental abnormalities that can be treated with therapy and supplemented by diet.
A diet rich in vitamins, minerals and fatty acids can help reduce aggression and improve mood. Studies in prisons found that inmates who received supplements had significantly fewer rule violations and violent incidents than those who received placebos. Similarly, studies in schools found that children who received omega-3 supplements performed better academically than those who received placebos. While more research is still needed, current evidence suggests nutrition may play an important role in mental health and behaviors.
Alergia a los almentos mediadas por anticuerpos ig g asociadas con la migraña...MEDIAGNOSTIC
This document discusses a study investigating the presence of IgG antibodies to foods in patients with migraine refractory to traditional treatment. The study found:
1) Statistical significant differences in the number of positive IgG food allergens between patients with migraine (56 patients) and a control group without migraine.
2) Elimination diets successfully controlled migraines in patients, without the need for medications.
3) According to the results, serum IgG antibodies to common foods should be investigated in patients with migraine.
What’s the latest news about MAP grants (including the MAP 2+2 pilot program), Pell grants, student loans, and funding for these programs? This session will provide an overview of the changes to state and federal financial aid programs for the 2012-13 school year, as well as provide updates on state and federal legislative, operational, and budgetary issues.
Terapia dello Shock Anafilattico - AdrenalinaFilippo Fassio
The document discusses guidelines for the assessment and management of anaphylaxis. It emphasizes the importance of promptly diagnosing anaphylaxis and administering epinephrine as the first-line treatment. While epinephrine is essential, the evidence for managing anaphylaxis is limited compared to other conditions. The guidelines focus on basic initial treatment that can be provided even in low-resource settings. Oxygen supplementation, intravenous fluids, and monitoring vitals are also recommended components of anaphylaxis management.
1. Allergic rhinitis is an inflammatory reaction of the nasal membranes caused by an immune response to allergens like pollen, dust mites, or mold. It is characterized by sneezing, nasal congestion, nasal itching, and rhinorrhea.
2. The major complications of allergic rhinitis include allergic sinusitis, asthma, and secretory otitis media.
3. Treatment involves avoiding allergens, using medications like antihistamines and nasal steroids, and immunotherapy which decreases allergen-specific IgE levels and increases blocking IgG antibodies over a long-term course of 2 years or
Este documento describe la fisiopatología, clasificación y manifestaciones clínicas de la urticaria y el angioedema. Explica que la urticaria se debe a la liberación de mediadores por los mastocitos en la piel, y puede ser aguda o crónica. La urticaria física se desencadena por estímulos como el frío o la presión. El angioedema causa hinchazón más profunda en la piel y puede afectar las mucosas. La evaluación debe incluir los antecedentes familiares y los desencadenantes
Este documento describe los síntomas, causas y tratamiento del prurito. El prurito, o picazón en la piel, puede estar presente con o sin lesiones visibles y puede ser localizado o generalizado. Tiene múltiples causas, incluyendo enfermedades de la piel, del hígado, riñones y sangre, así como factores ambientales, medicamentos e infecciones. El tratamiento implica identificar y tratar la causa subyacente, así como el uso de antihistamínicos, humectantes y en ocasiones esteroides
Urticaria, commonly known as hives, is a skin rash with pale red, itchy bumps that appear and disappear quickly. It is characterized by transient wheals (swellings) and angioedema (swelling of deeper layers of skin). Urticaria can be caused by allergic reactions, infections, physical stimuli like heat, cold, pressure, or vibrations. It is classified as acute, chronic, physical or contact urticaria. Treatment involves identifying and avoiding triggers, and using antihistamines.
Integrating the Functional, Psychodynamic, and Immunologic Matrix: New Advent...Louis Cady, MD
In this presentation (here represented in English before translation) Dr. Cady deconstructs the curious and sometimes perplexing manifestations of delayed sensitivity food allergy testing, supporting it with citations from the peer-reviewed medical literature and extensive bibliographic references. The importance of understanding the potential immunologic contribution to a patient's mental state is reviewed.
In his third of five lectures, Dr. Cady reviews the concepts of food allergy testing with IgG and IgE antibodies, traces the development of this body of knowledge from the 1960's, and reviews two illustrative cases.
Global Medical Cures™ | Guidelines for Diagnosis and Management of Food Aller...Global Medical Cures™
Global Medical Cures™ | Guidelines for Diagnosis and Management of Food Allergy in USA
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
1) The document discusses trying to understand the brain and autism spectrum disorder (ASD). It provides information on what a spectrum means, the history and definitions of autism from Kanner and Asperger, and how the brain works in processing sensory information, attention, and social interactions.
2) The document summarizes challenges people with ASD face in understanding the world, others' perspectives, and their own bodies/emotions. It reviews research on potential causes of ASD including hundreds of genetic factors.
3) Research on treatments is summarized including inconclusive evidence for supplements/diets but some evidence risperidone and melonin can help manage behaviors and sleep. Evidence for early intensive behavioral
Subtitle: The Moral Imperative of Integrative Medicine
This presentation, two hours in length, was delivered to the A4m MMI Audience in their Frontiers of Neurology - Module 3.
The following topics are reviewed:
- ADHD, Autism, Depression, Schizophrenia
- the impact of neuroinflammation on all of these.
- confounding factors and the ways to mitigate them: Omega6/Omega 3 imbalance in the Western diet, MTHFR polymorphism, the use of elemental lithium, the presence of intestinal dysbiosis and the role of gluten/dairy IgG Food allergies.
- pharmacogenomic testing
The Sage Delayed Food Allergy Test measures IgG and immune complex reactions to identify delayed food sensitivities. It tests for 44 common allergens using serum samples. Results show which foods may be triggering chronic health issues like headaches or digestive disorders. While some studies support the test's validity, others note a lack of standardized methodology and need for more rigorous testing. The test aims to help people with conditions not explained by traditional IgE testing alone.
A pilot study to evaluate nutritional influences on gastrointestinal symptoms...ivdacruz
A pilot study to evaluate nutritional influences on gastrointestinal symptoms and behavior patterns in children with Autism Spectrum Disorder1-s2.0-S0965229912001203-main
David Wiss MS RDN walks you through research on childhood adversity and the various ways that trauma can become embedded into physiology and impact health, such as eating behavior.
This document provides an overview and update on autism spectrum disorder (ASD) research. It summarizes several studies on various topics:
- Genetic factors are strongly implicated in ASD risk, though hundreds of genes may be involved.
- Early intensive behavioral intervention shows benefits for social/communication skills but evidence is limited.
- Some treatments like risperidone and melatonin show benefits for specific symptoms but evidence is still limited overall.
- Joint attention interventions effectively improve joint attention skills in children with ASD.
- Ongoing research is exploring new drug treatments and personalized approaches.
“STUDY ON THE IMPACT OF PRAKRITI IN CHILDREN WITH ACADEMIC STRESS AND EVALUAT...Dr-sumod Khedekar
“STUDY ON THE IMPACT OF PRAKRITI IN CHILDREN WITH ACADEMIC STRESS AND EVALUATION OF ANTISTRESS EFFECT OF SARASWAT CHURNA”
presented in Kochi International seminar.
This document summarizes research on the relationship between diet and Attention Deficit Hyperactivity Disorder (ADHD). It discusses several studies that have investigated eliminating certain foods like artificial dyes, sugars, or common allergens from children's diets to see if it reduces ADHD symptoms. The research has found that diet changes can significantly improve symptoms for a small subset of children with ADHD, possibly due to food sensitivities. However, results have been inconsistent. More research is still needed to better understand how diet may help manage ADHD symptoms for some individuals.
Natural Treatments for ADHD - April 11, 2018Louis Cady, MD
This presentation will be delivered April 11, 2018 on recorded webinar for the Autism Global Conference. It was my pleasure to prepare and present this lecture (in webinar form), outlining a coherent philosophy of finding biological underpinnings that can cause or contribute to, or exacerbate, mental dysfunction. In the case of this presentation, the question is "How much of ADHD symptomatology is caused by a lack of a good medication, or, rather, lack of a coherent strategy for finding and fixing underlying biological abnormalities?"
Those biological abnormalities in this presentation include MTHFR polymorphisms, COMT polymorphisms, elemental deficiencies (lithium, magnesium, zinc, iron, and copper), essential fatty acid deficiencies, the confound of high fructose corn syrup, and many others.
Rational strategies for nutraceutical intervention are reviewed.
Current Therapeutic Approaches in Anorexia Nervosa Edited.pptxRonakPrajapati63
1) Current therapeutic approaches for anorexia nervosa discussed in the document include restricting food intake, binge eating and purging behaviors, cognitive behavioral therapy, family therapy, and medication.
2) Anorexia nervosa is defined by significantly low body weight, an intense fear of gaining weight, and a disturbed perception of body weight and shape. Diagnostic criteria include in the DSM-5 and ICD-10 are discussed.
3) Risk factors for anorexia nervosa include genetic, biological, developmental, psychological, environmental, and social factors. The etiology is complex with both biological and psychosocial components.
This document summarizes a presentation on autism and special diets. It discusses the potential ways diet could help individuals with autism, including directly impacting neurotransmitters and brain structure, and indirectly by reducing pain/discomfort. It reviews evidence on gastrointestinal issues in autism and the need for increased celiac screening. It also summarizes recent studies on gluten-free/milk-free diets, probiotics, fish oils, vitamins/minerals, and enzymes, with some finding benefits but inconclusive results overall.
This document discusses the relationship between food allergies/sensitivities and behavioral/developmental disorders in children. It presents two case studies of children whose symptoms of ADHD, autism, and other CNS issues were linked to specific food allergens and additives through elimination diets. The author argues that foods can affect the CNS through various mechanisms beyond IgE-mediated allergies. Studies show links between conditions like asthma, depression, and anxiety, suggesting shared genetic or environmental factors rather than direct causation. Careful dietary management can effectively treat CNS issues in children with food sensitivities.
In his fourth and concluding lecture of the IMMH Conference in San Antonio, 2014, Dr. Cady reviews the statistics, epidemiology, biological nature and pharmacologic treatment of ADHD. The first part of the presentation was absolutely conventional allopathic psychiatry, inclusive of brain imaging.
The second part of the presentation considered: "If we are thinking about biological, psychological, and behavioral interventions for a 'psychiatric' patient, shouldn't we be considering the TWO biological levels?" The most normal biological level that "biologically trained psychiatrists" consider is medications and medication effectiveness. However, sometimes even the most vigorous, precise, and heroic efforts do not work. The potential confound it the underlying physiological, hormonal, nutrient, antioxidant, PUFA-rich state associated with optimal health and well being.
In the final analysis, shouldn't we make sure that we have BOTH of these biological foundations right?
We hope that you enjoy this provocative slide presentation.
The document summarizes findings from literature on eating disorders. It outlines 10 articles related to causes, risk factors, prevention, and treatment of eating disorders like anorexia and bulimia. Key points from the articles include the role of perfectionism, perceived incompetence and parental psychopathology in developing eating disorders. Family-based treatment and integrating oral healthcare with mental health services were discussed as effective prevention and intervention strategies.
The role of diet in managing immune dysfunction and inflammatory processes that contribute to ADHD and related neurodevelopmental disorders
ADHD is a neurodevelopmental disorder characterised by lack of attention, impulsiveness, and hyperactivity. Its cause is considered to be multifactorial, involving a combination of genetics, perinatal factors (e.g., low birth weight, prematurity, prenatal exposure to toxins such as alcohol and/or smoke), as well as environmental and socioeconomic factors.
The immune system is a key player in gut–brain interactions, with extensive alterations in immune function known to contribute to the pathophysiology of neurodevelopmental disorders, including dysregulated inflammation, elevated levels of pro-inflammatory cytokines and altered immune cell function. In this webinar Dr Nina Bailey will describe the role of immune dysfunction and inflammatory processes linked to the pathophysiology of neurodevelopmental disorders and will provide an overview of the nutritional interventions that can help to successfully manage symptoms.
Similar to New Adventures in Food Allergy Testing! 09 21 2013 (20)
SEND IN THE SHRINKS - 2009 Oliver CME seminarLouis Cady, MD
This one was fun.
I was invited by Dr. Randalll Oliver, MD, Founder of the Oliver Heachache and Pain Clinic in Evansville, to present to an audience of primary care practitioners about how to use pysychiatric mediations ("psychopharmacology") in clinical practice.
Along the way, I covered, ADHD and treatments, depression, anxiety, erectile dysfunction, hypoadrenia, and even touched on hypothyroidism. Although this presentation was in 2009, all of the drugs covered are stills in use, and, at times.... stupidly.
This presentation deconstructs the intricacies of selecting and antidepressant, particularly in the SSRI class.
What is the nature of QUALITY in medicine -for ASQ 11 14 2023.pptLouis Cady, MD
In this presentation, Dr. Cady deconstructs the tensions and stressors on both patients and health care providers in today's system.
This presentation reviews checklists foe liminating mistakes, the actual number of mistakes that are being made in medical practice, and what patients and their loved ones can do for self protection.
This isn't a "bash the doctor" presentation. It's a thoughtful, careful exploration of stresses and ramifications to the current US healthcare system.
This document provides information about a presentation given by Dr. Louis B. Cady on transcranial magnetic stimulation (TMS) as a treatment for depression. It begins with Dr. Cady's credentials and commercial disclosure stating he has received honoraria from several companies but that this presentation is not being underwritten by any company. The presentation then covers how TMS works, its safety and effectiveness compared to antidepressant medications and electroconvulsive therapy (ECT), and its inclusion in treatment guidelines for depression.
Hormones and Mental Health - Thyroid and Testosterone.pptxLouis Cady, MD
In this presentation for the Psychiatry Redefined program, Dr.
Cady breaks down and deconstructs the accepted, unthinking, "practice guideline based" notions of thyroid and tesotsterone, with there seemingly "normal" levels and dosing, versus what the actual peer reviewed medical literature says. In this presentation, do use of all forms of thyroid, and all forms of testosterone are reviewed. The idiocy of "T4 only treatment" is covered. The use of T4, T3, a combination of T4 and T3, and all of the porcine and compounded products is review.
In terms of testosterone, dr. Katie reviews the concept of "do you want to be optimal or do you want to be normal." He notes that it is "normal" for oil in cars to deteriorate and break down with age. It's also "normal" for men's and women's testosterone (as well as thyroid) to go down with age. The question is, "do we want to do anything about it?"
Logical ways of intervening in both the thyroid and female and male gonadal axes are covered. There is scrupulous attention paid to the thyroid hormone pathways, and the relevance of reverse T3 versus free T3. Similarly, in terms of women, the downstream effect of estradiol coming from testosterone is also reviewed.
The Moral Imperative of Integrative Medicine 2022.pptLouis Cady, MD
The document discusses the case of a 16-year-old teenager with a long history of treatment-resistant depression and anxiety. Previous medication trials with SSRIs, SNRIs, atypical antipsychotics, and lamotrigine had failed to provide sustained relief. Upon further evaluation, the doctor found potential contributing factors including an undiagnosed MTHFR gene mutation and hormonal imbalances. The doctor adjusted the teenager's supplements and medications, focusing on addressing the underlying functional issues. At follow-up several months later, the teenager reported significantly improved mood with only brief periods of low mood, though menstrual irregularities persisted.
CORONOFOBIA - Passos práticos para equilibrar as defesas do corpo e da menteLouis Cady, MD
Esta palestra, apresentada em 29 de maio de 2021 para o Congresso de Medicina Integrativa para a Saúde Mental 2020, promovido pelo Laboratório Great Plains no Brasil, enfocou coisas simples e de bom senso que os pacientes (e seus médicos) podem fazer para se manter seguros e viver durante o Pandemia do covid.
Os seguintes conceitos holísticos foram revisados:
- sono adequado e por que é tão importante;
- o uso de melatonina, cientificamente validada como tendo atividade antiviral (referências citadas);
- a importância de diminuir o estresse e técnicas para fazê-lo;
- a necessidade de "comer frutas e vegetais" como sua mãe e sua avó ensinaram devido à ingestão de carotenóides e antioxidantes ((referências citadas);
- o uso adequado de suplementos vitamínicos / nutricionais (referências citadas).
O foco desta apresentação não foram medidas heróicas para salvar vidas na unidade de terapia intensiva para pacientes gravemente enfermos com COVID, mas, sim, técnicas de bom senso, práticas, baratas e (em alguns casos) GRATUITAS para melhorar você e seus pacientes 'saúde e resistência às doenças.
THE MORAL IMPERATIVE OF INTEGRATIVE MEDICINE - O IMPERATIVO MORAL DA MEDICINA...Louis Cady, MD
Neste programa, o Dr. Cady baseia-se em uma série de casos clínicos para ilustrar a necessidade absoluta e moral do tratamento de precisão de nossos pacientes com todas as ferramentas disponíveis para uso por meio da medicina integrativa.
O uso de testes de polimorfismo MTHFR, testes convencionais e laboratoriais e testes farmacogenômicos foram revisados.
Os casos apresentados ilustram a trágica dificuldade de um menino com deficiência de MTHFR que estava prestes a desviar sua vida; um paciente esquizofrênico com vários problemas de medicina funcional que precisavam ser resolvidos (levedura, glúten, sensibilidade alimentar de IgG); uma estudante universitária a quem foi dito "não há nada de errado com você; seus laboratórios estão bem", embora ela tenha manifestado todos os sintomas relevantes de hipotireoidismo; e um CEO do sexo masculino de 42 anos que estava "tão cansado que parecia morrer" e que, na verdade, estava funcionalmente com pouco testosterona. O último caso revisado foi de um adorável garotinho que tinha autismo e foi recuperado por meio de uma abordagem focada e intensa de medicina integrativa.
Dr. Cady deconstructs some the medical literature about the use of nutrients - and the evidence of what happens in the presence of their insufficiency. Everything for decreased viral replication to decrease brain shrinkage is covered. The role of antioxidant and carotenoids, measured by the Pharmanex Biophotonic Scanner, is reviewed.
Please note - there is no representation that any nutrient or supplement can treat, prevent, mitigate, or cure any medical condition. It does seem, however, upon reflecting on the medical literature, that there seems to be a lot of evidence for therapeutic effect in the presence of good levels of nutrient, and harm to patients if they have insufficient levels.
The Moral Imperative of Integrative Medicine - IMMH 2020Louis Cady, MD
IN this presentation, Dr. Cady reviews several of the handful of functional, integrative medicine techniques required for a holistic and comprehensive management of psychiatric issues. MTHFR, hormone balance, diagnosis and treating intestinal dysbiosis, need for trace elements, and hormones (including thyroid, testosterone and estradiol) are reviewed.
This brief webinar, a gift to the local Jewish community and Temple Adath B'Nai Israel here in Evansville, IN, reviews the tradition of mindfulness and the interdigitation of Buddhist practices with some Jewish traditions. Dr. Cady reviews the downstream effects of stress, how meditation and mindfulness are useful tools and techniques, and actually how to practice it. Multiple references without being complicated or overdone are provided.
Webinar 5: Designing Your Future: WHAT'S COMING NEXT?Louis Cady, MD
In this capstone webinar presentation, closing out Dr. Cady's series on dealing with COVID 19, he turns his attention to a nunmber of interesting thems:
- what's the REAL case fatality rate of COVID 19
- How is it likely that society will reopen?
- What's going to happen in education and medicine?
- What's going to happen when the robots and AI arrive?
- What's the future going to be out 500 years?
HOW TO SAVE MONEY ON YOUR HEALTHCARE: An Integrative Medicine ApproachLouis Cady, MD
In this webinar, the fourth in a series of five from Dr. Louis Cady and the Cady Wellness Institute, we focus on the actual dollars and cents of health care expenditures, and the societal and PERSONAL costs of poor health maintenance behavior. We examine the essentially passive US medical system, that would rather drug a symptom than fix the underlying problem.
Great attention is paid on not shaming the patient or the doctors as they exist in the current system. Both groups "do not know what they do not know." Confirmation bias is rampant.
This webinar points the way to living a more vital, energetic life, with a minimum of cost, grief, and misery.
HOW TO COPE WITH THE PSYCHOLOGICAL IMPACT OF COVID 19 AND SOCIAL DISTANCINGis...Louis Cady, MD
In this presentation, Dr. Cady will review:
- What did Sparky learn about not being an emotional support animal?
- "Do it to yourself psychotherapy." Learn the following:
- What are the wrong - and the RIGHT ways of any sort of "behavioral therapy"?
- How to use a journal to think RATIONALLY and “get out of your head.”
- How to get out of your HEAD and into your LIFE.
- We'll cover all 10 of David Burns’ cognitive distortions, customized and gift-wrapped for dealing with COVID 19.
- We will cover actionable examples of how to reprogram yourself.
We will review What are the 3 P's of Positive Psychology and Learned Optimism?
The Cady 5 "5P’s” and “How to shrink yourself."
Can we find the GOOD in COVID?
This presentation is meant to be provocative and to challenge you mentally, intellectually, and emotionally. Some of the great thinkers and exemplars of human performance and possibility are featured.
BOOSTING YOUR IMMUNITY During the COVID 19 PandemicLouis Cady, MD
In this presentation, presented as a live webinar on Monday, April 27th, Dr. Louis Cady of the Cady Wellness Institute reviewed practical, common-sense things that can be done to boost your immunity, with documentation from the peer-reviewed medical literature. Dr. Cady also reviews supplements and nutrients that are established in the peer-reviewed medical literature as having antiviral capabilities. These include Vitamins C,D, and E, Zinc, carotenoids and antioxidants, probiotics, the reishi mushroom, elderberry, cannabidiol (CBD - not marijuana or weed!).
Points presented are scrupulously documented from the medical literature. This presentation does not guarantee or represent that using ANY of these nutrients will "keep you from getting infected or dying" from COVID 19. They are presented for your thoughtful consideration.
Tratamento holistica de ezschizophrenia - São Paulo, Brazil April 20, 2019Louis Cady, MD
Esta é a versão em inglês da apresentação do Dr. Cady feita na UNIP (Campus Paraiso - São Paulo, SP Brasil) para o Congresso de Saúde Mental de 2019 (Conferência sobre Saúde Mental). Foi entregue em 20 de abril de 2019.
Nesta apresentação, o Dr. Cady analisa brevemente a história da esquizofrenia, a falha do bloqueio do receptor de dopamina D2 como uma cura universal na esquizofrenia, e várias intervenções holísticas que podem impactar forte e positivamente os sintomas da esquizofrenia. Incluídos na pesquisa do Dr. Cady estavam o papel dos ácidos graxos essenciais, deficiências nutricionais (particularmente vitaminas do complexo B), o perigo de supercrescimento da cândida, testes farmacogenômicos, polimorfismos da MTHFR e muito mais.
Foi uma honra e um privilégio entregar esta apresentação em
São Paulo.
Para mais informações no Brasil sobre este tema, ou para solicitar uma gravação em vídeo / áudio da conferência, entre em contato com Luiz Dias do Laboratório Grandes Planícies no Brasil.
Slides, até o apêndice, são traduzidos por Luiz Dias.
This lecture was presented on March 29, 2019 in Rapid Citry, South Dakota, for the conference co-sponsored by the Manlove Psychiatric Group and the Brain Injury Center.
It reviews the uptick in diagnosis of ADHD, the raiontale for its concern, causative factors, and how it can be worked up holistically and in a balanced, not necessarily medication-oriented way.
Use of high dose fish oil, iron supplementation, and how to overrcome nutritional deficiencies are discussed.
This document provides an overview of a lecture on thyroid health. It begins with the speaker, Louis Cady, MD, disclosing commercial relationships and interests. It then outlines the structure of the lecture, which will cover thyroid basics, practical information, and conclusions. The document discusses conventional thyroid testing and its limitations. It also reviews factors that affect thyroid hormone production and conversion. Overall, the document introduces topics to be covered in the lecture regarding thyroid function and testing.
The document summarizes a presentation on the holistic medicine approach to treating schizophrenia. It discusses the multiple domains affected by schizophrenia, including positive and negative symptoms, cognitive dysfunction, and social deficits. It reviews the etiology and pathogenesis of schizophrenia. It then presents a case study of a patient with schizophrenia who was treated holistically over many years with integrative testing to identify deficiencies and allergies, dietary changes, supplements, low dose lithium, and antifungals. The patient showed significant improvement with this approach.
A abordagem da Medicina Integrativa para o Tratamento da EsquizofreniaLouis Cady, MD
This is the presentation that Dr. Cady gave in São Paulo, Brazil, in October of 2017 on the integrtive treatment of schizophrenia. The one in English is already posted. My thanks to Luiz Dias, of Laboratorio Great Plans in Brazil, for his impeccable translation.
Endocannabinoid System - Literature ReviewLouis Cady, MD
In this brief review of the literature, Dr. Louis Cady of the Cady Wellness Institute reviews the endocannabinoid system and the role it plays in bridging the connection between mind and body, modulating anxiety, inflammation, memory and other physiological processes. Nothing in this presentation suggests that any of the products mentioned are appropriate for the treatment, remediation, cure, or prevention of any disease or illness. It does appear, however, that this natural, indwelling, genetically passed down endocannabinoid system may have major implications for holistic physicians and health care practitioners, and for the patients that they serve.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfRahul Sen
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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New Adventures in Food Allergy Testing! 09 21 2013
1. Adjunct Asst. Prof of Psychiatry – Indiana University School of
Medicine Department of Psychiatry
Child, Adolescent, Adult, Functional Neuropsychiatry – Evansville,
Indiana
4rth Annual MMH CONFERENCE – Chicago, IL.
Saturday, September 21, 2013
New Adventures in Food Allergy Testing
Louis B. Cady, MD – CEO & Founder – Cady Wellness InstituteLouis B. Cady, MD – CEO & Founder – Cady Wellness Institute
2. Continuing Medical Education Commercial Disclosure Requirement
for Louis B. Cady, M.D.
I, Louis B. Cady, MD, have the following commercial relationships to
disclose:
•Speaker honoraria received from:
• Immunolaboratories, Great Plains Diagnostic Labs, LABRIX
•Speaker’s bureaus (active) for:
• Forest Pharmaceuticals, Sunovion, Shionogi
•Historical data – speaker’s bureau for Bristol-Myers Squibb,
Celltech, Cephalon, Eli Lilly, Glaxo-Smith Kline, Janssen, McNeil,
Pfizer-Roerig, Sanofi!~aventis, Sepracor, Shire, McNeil, Takeda,
Janssen, Searle, Shire, Takeda, Wyeth-Ayerst
8. This model of human IgG1 was created
by E. A. Padlan -- "Anatomy of the
Antibody Molecule." Molecular
Immunology 31:169 (1994)
HUMORAL Immunity
“Globulin molecules
capable of attacking the
invading agent.” [Guyton]
9. Actions and downstream effects
• Direct action of antibodies:
– Agglutination, precipitation, neutralization,
lysis
• Downstream effects: complement
activation:
– Lysis, opsonization/phagocytosis, chemotaxis,
agglutination, neutralization of viruses,
INFLAMMATORY EFFECTS
10. The Classical Pathway of Complement Activation
http://www.youtube.com/watch?v=gNvHLStz-VA
11. It can therefore be hypothesized that all the
components of the circulatory humoral system are
participating in this reaction and that Type II, the
cytotoxic, and Type III, the immune-complex type of
immunologic reaction, are the major contributors in
the production of symptoms.
It can therefore be hypothesized that all the
components of the circulatory humoral system are
participating in this reaction and that Type II, the
cytotoxic, and Type III, the immune-complex type of
immunologic reaction, are the major contributors in
the production of symptoms.
Trevino RJ. Laryngoscope. 1981
Nov;91(11):1913-36.
12. De Weck Al. Ann Allergy. 1984
Dec;53(6 Pt 2):583-6.
De Weck Al. Ann Allergy. 1984
Dec;53(6 Pt 2):583-6.
“antigen-IgG complexes generating
anaphylatoxins…”
13. ADHD Diagnosis
DSM-IV (TR)
–SIX Symptoms present
before age 7 years
–Impairment from symptoms
present in 2 or
more settings
–Significant social, academic,
or occupational impairment
–Exclude other mental
disorders
DSM-V
–Symptoms rewritten
slightly
• FIVE only required for
adults
15. Food Allergies and ADHD in the Literature
• Get “THE THINKER” illustration•Food allergies presumed to be related to ADHD
•Before 1976 – No known relationship between FA and ADD
•1976 – IgE reactivity + food allergies = decreased IQ
•1985 – d/c of antigenic foods = ADHD improvement
•1993 – more confirmation
•1994 – some kids that got better on diet did NOT have IgE
reactivity
•2003 – evidence mounting for non-IgE sensitivities related to food
allergies]
•2002 – 2011 Pelsser LM et al – SIX published papers (European
and Dutch literature, cf: www.pubmed.gov).
•73 papers, at present – 8/03/2013
16. Millman, et al – the groundbreaking
article
• “Allergy & Learning Disabilities in Children” – Annals
of Allergy, 1976 [36:3, 149-160.]
• “The allergic tension-fatigue syndrome observed by Speer”
– “A symptom complex accepted by many allergists.”
• Food allergies established by scratch testing or intradermal
injections
• Positive correlation between [IgE] food
allergies and IQ scores.
–The more the food allergies, the
lower the IQ scores.
17. Oligoantigenic diet (w/o testing)
• “Controlled trial of oligoantigenic treatment in the
Hyperkinetic Syndrome.” Egger et al. Lancet,
March 9, 1985, 540-545.
• No testing performed
• Children empirically placed on restrictive diet.
– Two meats, two carb sources, two fruits, one vegetable,
water, calcium, vitamins.
• No food allergy symptoms were provoked; ADHD
improved.
18. The crossover study – no
distinguishing between IgE and IgG
• “Effects of a few foods diet on ADD.” Carter et al, Archives
of Disease in Childhood, 1993;69:564-568.
• “Few foods” elimination diet
– 59 of 78 children improved.
• “This trial indicates that diet can contribute to behavior
disorders in children and that this effect can be shown in a
double blind, placebo controlled trial.”
• “The ways in which [this] diet worked remain
unclear. Toxic pharmacological, or allergic
mechanisms could be involved, and the
physiological effects of different foods may vary.”
19. Profound cautions
• “Effects of a few foods diet on ADD.” Carter et al, Archives
of Disease in Childhood, 1993;69:564-568 (cont.)
• “The treatment, as applied in this study, has
disadvantages. It is a difficult and exacting
regimen, which puts a considerable strain on
the whole family. It is not yet clear whether modified
diets can also be effective…. It may therefore be possible
to devise a less restricted diet with similar levels of
success.”
• Cady impression: “Shooting in the dark is dangerous.”
20. The appearance of IgG
• “Foods and additives are common causes of
ADHD in children.” Boris, et. al. Annals of Allergy,
vol.. 72, 1994, 462-468.
• “DBPCF” - “double blind placebo controlled
food challenge test”
• 4/19 children who showed improvement
with removal of offending foods were non-
atopic.
21. Pelsser publishes - 2002
• “few foods diet” – {rice, turkey, pear &
lettuce} in 40 children
– 36 boys, 4 girls; 3-7 years of age, all dx with
ADHD}
• Results:
– 25 patients (62%) improved behavior >/= 50%
– 10 (25%) had improved parent/teacher ratings.
– 9 (23%) withdrew from study
Pelsser LM, Buitelaar JK. Favourable effect of a standard elimination diet on
the behavior of young children with attention deficit hyperactivity disorder
(ADHD): a pilot study. Ned Tijdschr Geneeskd. 2002;146(52):2543–2547
22. “IgE and Non IgE Food Allergy”
• Sabra, et al. Annals of Allergy, Asthma, and
Immunology 2003;90 (Suppl 3)71-76.
• “The gastrointestinal tract serves not only a
nutritive function but also is a major immunologic
organ. Although previously thought to be triggered
primarily by an IgE mediated mechanism of injury,
considerable evidence now suggests that non-
IgE mechanisms may also be involved in the
pathogenesis of FA (“food allergy”).
23. Pelsser publishes (again)- 2011
• “Impact of Nutrition Study on Children with ADHD”
• 100 children, 4-8 years of age with ADHD
– Open label phase – 5 weeks of a restricted elimination
diet (“diet group”) OR healthy control diet (50 kids each)
– THEN – 4 week double-blind crossover challenge of “diet
group” responders
• Challenge responders:
– With either HIGH or LOW IgG reactivity (per testing):
• increase of 20.8 point on ADHD [ARS] rating scale (p<0.0001)
• 11.6% increase of a Conner’s score (p<0.0001)
• After challenge – 63% of children relapsed
Pelsser LM, Frankena K, Toorman J, et al. Effects of a restricted elimination
diet on the behaviour of children with attention-deficit hyperactivity disorder
(INCA study): a randomised controlled trial. Lancet. 2011;377(9764):494–503
24. What does a 20.8 point increase in ARS
mean???
Number crunching:
•9 symptoms of
inattentiveness & 9 of
hyper/impuls = 18.
•Lichert scale {0 – 3}
•Max score = 18 *3 = 54
points
•20.8 points = 39% of
range.
• Assume little Johnny has dropped from 45 to 18 in phase II of study (40%
drop which was required.)
• Increase from 18 +20.8 points = 39 points = 2.16 X increase in sxs.
25. • Drug examples:
– Fluoxetine at 80 mg (max dose) gets
increased to 172.8 mg
– LiCO3 gets increased from 1200 mg/d to
2,592mg of Li+/day
– LIPITOR – goes from 80 mg to 172.8 mg
Well, what does a 2.16 X effect mean?
• My favorite: a speeding ticket for 75 mph in a
70 mph zone gets increased to going 162 mph!!
26. FROM HYPERNESS TO
HEADACHES
…and joint pains,
migraines, brain fog,
irritable bowel
syndrome, asthma,
fatigue, misc. aches
and pains
28. Mechanisms of behavioral, atopic, and other
reactions to artificial food colors in children
[Stevens LJ et al. Nutr. Rev. 2013 May; 71(5):268-81]
• “… a subgroup of children (with or without
ADHD) react adversely to challenges with
AFC’s.”
• “Children with ADHD show EXCESS
inattention, impulsivity, and hyperactivity.”
• “Studies using at least 50 mg of AFC’s
showed a greater % of children who reacted
to the challenge.”
29. Neltner, T. JAMA Internal Medicine
August 7, 2013
Neltner, T. JAMA Internal Medicine
August 7, 2013
In a previous study, Neltner and his colleagues estimated that
about 43 percent of the 10,000 or so additives allowed in food
were on the FDA's GRAS list, with other additives approved
through other means or not submitted to the FDA.
Manufacturers made their own safety
determinations for about 1,000 additives without
ever notifying the agency.
In a previous study, Neltner and his colleagues estimated that
about 43 percent of the 10,000 or so additives allowed in food
were on the FDA's GRAS list, with other additives approved
through other means or not submitted to the FDA.
Manufacturers made their own safety
determinations for about 1,000 additives without
ever notifying the agency.
30. Millichap & Yee. Vol 129, no. 2 Feb 1 2012 – pp 330-
337
Full article:
• Diets reviewed:
– Sugar restricted. Additive/preservative free,
elimination diet and FATTY ACID SUPPLEMENTS
• NOTABLE: “ADHD-associated Western diet”
high in fat and refined sugars
• ADHD-free [sic] healthy diet: {fiber, folate, and
omega 3 fatty acids.
• Multiple cits. on + results with IgG elimination
31. Millichap & Yee. Loc. Cit.
• Other findings:
– Strong results with Omega 3 & 6 supplementation.
• (doses of 300 – 600 omega 3 and 30-60 mg Omega 6/d)
– Benefits of zinc supplementation
• (optimal dose of d-amphetamine was 37% lower with zinc
than with placebo)
– Children are more sensitive to reactive
hypoglycemia than adults: AVOID SUGAR LOAD.
– Unusually low ferritin levels {18.4ng/ml, mean}
correlated with baseline inattention, hyperactivity
and impulsivity.
• Also correlated with dose of d-amphetamine required.
32. Association of atopic and non-atopic asthma
with emotional symptoms in school children
• Cross sectional data on asthma and allergic
diseases at 10 year follow-up of two birth cohorts.
– Atopic = “asthma ever and + IgE test”
– Non-atopic = “asthma ever and NEGATIVE IgE”
• “Non atopic asthma was associated with about 3-
fold higher likelihood of emotional symptoms
compared to children with no asthma.” [OR = 2.90,
CI 95% = 1.46-5.73]
• Atopic asthma – not associated with emotional
symptoms [OR 1.35]
Kohlboeck G et al. Pediatr Allergy Immuno. 2013 May; 24(3):230-
6
33. Serological tests in gluten sensitivity
(nonceliac gluten intolerance)
• “Gluten sensitivity” noted to be recently identified
as a new clinical entity included in spectrum of
gluten-related disorders.
• Study - Sera from 78 patients with GS + 80 patients with
celiac disease was retrospectively analyzed for:
– immunoglobulin (Ig)G/IgA antigliadin antibodies
– IgG deamidated gliadin peptide antibodies
– IgA tissue transglutaminase antibodies (tTGA)
– IgA endomysial antibodies (EmA)
Volta U, et al. J Clin Gastroenterol. 2012 Sep;46(8);680-5.
34. Serological tests in gluten sensitivity
(nonceliac gluten intolerance)
• Patients with GS had intestinal and extraintestinal
symptoms
– Abdominal pain, bloating, diarrhea, constipation
– “foggy mind,” tiredness, eczema/skin rash, headache,
joint/muscle pain, numbness of legs/arms, depression,
and anemia
• NORMAL or MILDLY ABNORMAL small intestinal
mucosa
• CONCLUSIONS: “The serological pattern of GS is
characterized by IgG AGA positivity in more than
half of the cases.”
Volta U, et al. J Clin Gastroenterol. 2012 Sep;46(8);680-5.
35. “Is a subtype of autism an allergy of
the brain?”
Theoharides, TC. Clin Ther. 2013 May; 3595):584-91.
• Methods – PubMed search since 1995:
associations between autism/ASD’s and
“allergy, atopy, brain, corticotropin-releasing
hormone, cytokines, eczema, food allergy,
food intolerance, gene mutation,
inflammation, mast cells, mitochondria”…
[etc.]
• “Children with ASD…present with food and
skin allergies that involve mast cells (IgE).”
36. “Is a subtype of autism an allergy of
the brain?”
Theoharides, TC. Clin Ther. 2013 May; 3595):584-91.
• “Activation of brain mast cells by
allergic, environmental, immune,
NEUROHORMONAL, stress, TOXIC
TRIGGERS, especially in those areas
associated with behavior and language,
lead to focal brain allergies and
subsequent focal encephalitis.”
37. Food allergy and autism spectrum
disorders: is there a link?
Jyonouchi H. Curr Allergy Asthma Rep. 2009 May;9(3):194-201
• “ Our previous studies indicated a high
prevalence of non-IgE mediated FA in
young children with ASD’s.”
• “…non-IgE-mediated FA may
account for some but not all GI
symptoms observed in children
with ASDs.”
38. Anxiety & depression in patients with self-
reported food hypersensitivity
• 130 consecutive patients and 75 random healthy
volunteers
– Completed the Hospital Anxiety and Depression Scale
(HADS)
• 57% of patients fulfilled a DSM-IV criteria for at
least one psychiatric disorder.
– Anxiety disorders – 34%
– Depression – 16%
• Food hypersensitivity rarely confirmed by
provocation tests. (Non IgE)
• 81% of patients had irritable bowel syndrome
Lillestol K et al. Gen Hosp Psychiatry. 2010 Jan-Feb; 32(1):42-8.
39. IgG food allergies in IBS
• 150 outpatients with IBS randomized to diet
excluding all IgG reactive items or a sham diet
(excluding the same number of foods but not the
ones to which they had antibodies)
– 25% reduction in IBS symptoms in fully compliant
patients
– 10% reduction in moderately compliant
• “Food elimination based on IgG antibodies
may be effective in reducing IBS symptoms
and is worthy of further medical research.”
Atkinson, W et al. Food elimination based on IgG antibodies in irritable bowel
syndrome: a randomised controlled trial. Gut. 2004 Oct;53(10):1459-64.
40. Gluten – one of the ultimate “bad
boys” in food sensitivities
• Headaches
• Tearing up your gut
• Depression
• Suicide*
– * Untreated celiac
disease and
attempted suicide.
Lancet, September
1995. Pelligrino et al
41. Gluten and neurologic disease
• “More recent studies have emphasized that
a wider spectrum of neurologic syndromes
may be the presenting extraintestinal
manifestation of gluten sensitivity with or
without intestinal pathology.”
– -Bushara, KO. Neurologic presentation of
celiac disease – Gastroenterology. 2005 Apr;
128(4 Suppl 1):592-7.
42. “UBO’s on MRI” – the gluten
connection
• 10 patients – had headaches.
– MRI
– UBO’s
• 6 – unsteady, 4 gait ataxia
• 90% response rate to gluten free diet.
44. Corvaglia, et al 1999
• 3 adult patients found with undiagnosed/untreated
celiac disease
• Found by pediatricians who noted family history
when child’s medical history obtained.
• Celiac disease diagnosis was MADE in childhood,
but diet was stopped due to no more GI
symptoms.
• In all three patients, depressive symptoms
improved with gluten free diet.
45. Does it have to be celiac/gluten to
mess up your head?
“According to the results obtained, serum IgG
antibodies to common food should be investigated
in patients with migraine.”
“According to the results obtained, serum IgG
antibodies to common food should be investigated
in patients with migraine.”
48. Photos deleted for syllabus materials. The
presenter has permission to use the patient’s
photos during the live presentation only.
49. Criticality of removing IgG antigens
(+ complete, holistic approach)
RX: dairy free diet (+IgG test); D3 5000 IU/d; Armour thyroid,
Testosterone cypionate 100 mg IM q wk, MVI, Zinc, DHEA 50 mg
(photo shot 15
months after tx)
(permission granted to use photos & data)
Photos deleted for syllabus materials. The
presenter has permission to use the patient’s
photos during the live presentation only.
50. Photos deleted for syllabus materials. The
presenter has permission to use the patient’s
photos during the live presentation only.
51. Just one more: Rusty- 6/28/11 “The
kid that wouldn’t poop.”
• 11 year old male 5th
grader with dx of ADHD and
Speech Apraxia; problems with reading, writing, oral
expressive language, math, sequencing
• Medical:
– Hx of “lazy bowel”
• “He doesn’t go more than once in two weeks.”
• Dietary: likes cheese, chicken nuggets, ice cream, Coke, pizza.
Used to like cottage cheese.
– GI sxs refractory to pediatric interventions
• Dx 1: ADD: 6/9 sxs of inattentiveness ON RX.
• Dx 2:“Probable severe IgG food sensitivity with
obvious stool retention problems”
52. Dairy IgG sensitivity suspected.
Testing/Results:
• Pediatrician ordered IgE RAST = NEGATIVE
• 7/25/11 – no change. 2 BM’s in one month.
– IgG Testing previously ordered. (Mom resistant
and delayed due to cost. Finally done after this
appt). RESULTS……
54. The kid that wouldn’t poop, concl.
• 8/15/11 – milk/wheat stopped.
• Constipation and fecal retention
totally eliminated within 1 week.
• Follow-up: “He won’t follow the
diet.” Mom wimped out. Now
constipated again.
55. What to be looking for…
• Obvious GI problems
• Meds not working.
• Chiro adjustments don’t
“hold.”
• Atypical presentations
• KNOWN associations
(autism)
• Symptoms varying with diet
• Excess ABX use (candida)
• Lack of normal progression
in treatment
56. Diagnostic challenges & IgG food
sensitivities - opportunities exist
• “Tough cases”
• Weird, multiple symptoms
• Headaches
• GI symptoms, food cravings, or both
• ADHD and “bipolar” type symptoms
• Processing issues (no pills available!)
• Headaches resistant to standard
chiropractic and medical tx
• Fatigue, “brain fog”, temper fits
58. Louis B. Cady, M.D. www.cadywellness.com
www.facebook.com/cadywellness www.tms-relief.com
Office: 812-429-0772 E-mail: lcady@cadywellness.com
4727 Rosebud Lane – Suite F ~ Interstate Office Park Newburgh, IN 47630 (USA)
TWITTER FEEDS: @LouisCadyMD @TMS4depression
Once more….
Where to “get the slides” -
Syllabus
www.slideshare.net/lcady
md
Cady Wellness Institute
app.
Editor's Notes
De rerum natura (English: On the Nature of Things ) is a 1st century BC epic poem by the Roman poet and philosopher Lucretius with the goal of explaining Epicurean philosophy to a Roman audience. The poem, written in dactylic hexameter, is divided into six books, and explores Epicurean physics through richly poetic language and metaphors. Source: Wikipedia
Antibodies to a variety of foods, and in particular cereals, were measured in serum from 100 patients with acute psychoses and 100 elective surgical patients. For 13 out of 14 foods to which non-IgE antibodies were detected the schizophrenics had slightly more antibodies than the controls. There was an association between a possible secondary mania and the presence of IgE antibodies to wheat or rye. However, neither the schizophrenia nor the mania findings can be regarded as evidence for food allergy causing psychiatric disorder , since the immunological findings in both cases may represent consequences of the illnesses or their treatment, rather than causes of the illness.