This document contains a slide deck presentation on hemp oil and the endocannabinoid system. It discusses the history of research on cannabis, the endogenous cannabinoid system, and how various interventions can upregulate this system. Throughout, it stresses that the information is for educational purposes only and that no claims are being made about Zilis products treating, preventing, or curing any diseases.
Natural Treatments for ADHD (TADH) in Sao Paulo, Brazil, for Laboratorio Grea...Louis Cady, MD
In this presentation, given at UNIP (Campus Paraiso - Sao Paulo, SP Brazo) for the 2019 Congresso de Saude Mental (Conference on Mental Health), Dr. Cady reviewed the prevalence, inheritability, and social ramifications of ADHD (TADH in Brazil). He specifically reviewed multiple holistic interventions, including limiting "electric screen time,"good quality diet with adequate amounts of essential fatty acids and critically important trace elements, and the use of pharmacogenomic testing as well as functional, integrative medicine testing, all to better characterize logical and reeasonmable points for holistic intervention.
This presentation was simultaneously translated into Portugue for the attendees, but unfortunately the slides were not available in translated form.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
Thyroid, Adrenals, and Sex Steroids - A Balancing ActLouis Cady, MD
This was the second presentation gibven on MZarch 29, 2019 at the Manlove Psychiagtric Group and Brain Injury Institute spring conference in Rapid City, SD.
In this presentation, Dr. Cady carefully goes over the necessity of integrating and overview and awareness of hormones and their levels in the elucidation of what truly is going on with the patient.
This was an overview lecture only. Dr. Cady will be presenting a 16 hour CME program in Austin Texas on June 22 and 23 for the National Procedures Institute, and will explore all aspects of all relevant hormones and what can be done to manage and optimize them.
The integrative treatment of schizophrenia brazil 2019Louis Cady, MD
This is the English language version of Dr. Cady's presentation given at UNIP (Campus Paraiso - Sao Paulo, SP Brazil) for the 2019 Congresso de Saude Mental (Conference on Mental Health). It was delivered April 20, 2019.
This presentation also includes extra slides in the appendix that were not presented, and, unfortunately, these slides of the appendix have not been translated in the Portuguse version of this presentation.
In this presentation (Portuguese presentation will also be posted next), Dr. Cady briefly reviews the history of schizophrenia, the failure of the dopamine D2 receptor blockage as a universal cure-all in schizophrenia, and various holistic interventions which can strongly and positively impact symptoms of schizophrenia. Included in Dr. Cady's survey were the role of essential fatty acids, nutrient deficiencies (particularly B vitamins), the danger of overgrowth of candida , pharmacogenomic testing, MTHFR polymorphisms, and more.
It was an honor and a privilege to deliver this presentation in
São Paulo,.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
The Do It To Yourself Treatment of Depression - Webinar #3Louis Cady, MD
This is the third in a series of five webinars. The first was on staying alive by boosting your immunity during COVID 19. The second was on not screwing yourself up inside your head. This third one encompasses a romp through the peer reviewed medical literature looking for supplements and nutrients that you could use to self treat depression at home, CAREFULLY. Numerous cautions and warnings are included.
The driving impetus to this program is that many people - due to social isolation and their mental health care, or medical practitioners' offices being closed down - have not been able to get help or succeed in optimizing their treatment for depression. There are multiple useful nutrients for both depression and anxiety in nature's abundant pharmacopeia, and this webinar touches on just a few of them.
I hope you enjoy it.
Subtitle: The Moral Imperative of Integrative Medicine
This presentation, two hours in length, was delivered to the A4m MMI Audience in their Frontiers of Neurology - Module 3.
The following topics are reviewed:
- ADHD, Autism, Depression, Schizophrenia
- the impact of neuroinflammation on all of these.
- confounding factors and the ways to mitigate them: Omega6/Omega 3 imbalance in the Western diet, MTHFR polymorphism, the use of elemental lithium, the presence of intestinal dysbiosis and the role of gluten/dairy IgG Food allergies.
- pharmacogenomic testing
This document provides an overview of a lecture on thyroid health. It begins with the speaker, Louis Cady, MD, disclosing commercial relationships and interests. It then outlines the structure of the lecture, which will cover thyroid basics, practical information, and conclusions. The document discusses conventional thyroid testing and its limitations. It also reviews factors that affect thyroid hormone production and conversion. Overall, the document introduces topics to be covered in the lecture regarding thyroid function and testing.
This lecture was presented on March 29, 2019 in Rapid Citry, South Dakota, for the conference co-sponsored by the Manlove Psychiatric Group and the Brain Injury Center.
It reviews the uptick in diagnosis of ADHD, the raiontale for its concern, causative factors, and how it can be worked up holistically and in a balanced, not necessarily medication-oriented way.
Use of high dose fish oil, iron supplementation, and how to overrcome nutritional deficiencies are discussed.
The Moral Imperative of Integrative Medicine - IMMH 2020Louis Cady, MD
IN this presentation, Dr. Cady reviews several of the handful of functional, integrative medicine techniques required for a holistic and comprehensive management of psychiatric issues. MTHFR, hormone balance, diagnosis and treating intestinal dysbiosis, need for trace elements, and hormones (including thyroid, testosterone and estradiol) are reviewed.
Natural Treatments for ADHD (TADH) in Sao Paulo, Brazil, for Laboratorio Grea...Louis Cady, MD
In this presentation, given at UNIP (Campus Paraiso - Sao Paulo, SP Brazo) for the 2019 Congresso de Saude Mental (Conference on Mental Health), Dr. Cady reviewed the prevalence, inheritability, and social ramifications of ADHD (TADH in Brazil). He specifically reviewed multiple holistic interventions, including limiting "electric screen time,"good quality diet with adequate amounts of essential fatty acids and critically important trace elements, and the use of pharmacogenomic testing as well as functional, integrative medicine testing, all to better characterize logical and reeasonmable points for holistic intervention.
This presentation was simultaneously translated into Portugue for the attendees, but unfortunately the slides were not available in translated form.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
Thyroid, Adrenals, and Sex Steroids - A Balancing ActLouis Cady, MD
This was the second presentation gibven on MZarch 29, 2019 at the Manlove Psychiagtric Group and Brain Injury Institute spring conference in Rapid City, SD.
In this presentation, Dr. Cady carefully goes over the necessity of integrating and overview and awareness of hormones and their levels in the elucidation of what truly is going on with the patient.
This was an overview lecture only. Dr. Cady will be presenting a 16 hour CME program in Austin Texas on June 22 and 23 for the National Procedures Institute, and will explore all aspects of all relevant hormones and what can be done to manage and optimize them.
The integrative treatment of schizophrenia brazil 2019Louis Cady, MD
This is the English language version of Dr. Cady's presentation given at UNIP (Campus Paraiso - Sao Paulo, SP Brazil) for the 2019 Congresso de Saude Mental (Conference on Mental Health). It was delivered April 20, 2019.
This presentation also includes extra slides in the appendix that were not presented, and, unfortunately, these slides of the appendix have not been translated in the Portuguse version of this presentation.
In this presentation (Portuguese presentation will also be posted next), Dr. Cady briefly reviews the history of schizophrenia, the failure of the dopamine D2 receptor blockage as a universal cure-all in schizophrenia, and various holistic interventions which can strongly and positively impact symptoms of schizophrenia. Included in Dr. Cady's survey were the role of essential fatty acids, nutrient deficiencies (particularly B vitamins), the danger of overgrowth of candida , pharmacogenomic testing, MTHFR polymorphisms, and more.
It was an honor and a privilege to deliver this presentation in
São Paulo,.
For further information in Brazil on this topic, or to order a video/audio recording of the conference (in Portuguese),contact Luiz Dias of Laboratorio Great Plains in Brazil.
The Do It To Yourself Treatment of Depression - Webinar #3Louis Cady, MD
This is the third in a series of five webinars. The first was on staying alive by boosting your immunity during COVID 19. The second was on not screwing yourself up inside your head. This third one encompasses a romp through the peer reviewed medical literature looking for supplements and nutrients that you could use to self treat depression at home, CAREFULLY. Numerous cautions and warnings are included.
The driving impetus to this program is that many people - due to social isolation and their mental health care, or medical practitioners' offices being closed down - have not been able to get help or succeed in optimizing their treatment for depression. There are multiple useful nutrients for both depression and anxiety in nature's abundant pharmacopeia, and this webinar touches on just a few of them.
I hope you enjoy it.
Subtitle: The Moral Imperative of Integrative Medicine
This presentation, two hours in length, was delivered to the A4m MMI Audience in their Frontiers of Neurology - Module 3.
The following topics are reviewed:
- ADHD, Autism, Depression, Schizophrenia
- the impact of neuroinflammation on all of these.
- confounding factors and the ways to mitigate them: Omega6/Omega 3 imbalance in the Western diet, MTHFR polymorphism, the use of elemental lithium, the presence of intestinal dysbiosis and the role of gluten/dairy IgG Food allergies.
- pharmacogenomic testing
This document provides an overview of a lecture on thyroid health. It begins with the speaker, Louis Cady, MD, disclosing commercial relationships and interests. It then outlines the structure of the lecture, which will cover thyroid basics, practical information, and conclusions. The document discusses conventional thyroid testing and its limitations. It also reviews factors that affect thyroid hormone production and conversion. Overall, the document introduces topics to be covered in the lecture regarding thyroid function and testing.
This lecture was presented on March 29, 2019 in Rapid Citry, South Dakota, for the conference co-sponsored by the Manlove Psychiatric Group and the Brain Injury Center.
It reviews the uptick in diagnosis of ADHD, the raiontale for its concern, causative factors, and how it can be worked up holistically and in a balanced, not necessarily medication-oriented way.
Use of high dose fish oil, iron supplementation, and how to overrcome nutritional deficiencies are discussed.
The Moral Imperative of Integrative Medicine - IMMH 2020Louis Cady, MD
IN this presentation, Dr. Cady reviews several of the handful of functional, integrative medicine techniques required for a holistic and comprehensive management of psychiatric issues. MTHFR, hormone balance, diagnosis and treating intestinal dysbiosis, need for trace elements, and hormones (including thyroid, testosterone and estradiol) are reviewed.
Introduction to Integrative Medicine for Mental HealthLouis Cady, MD
This is the first of three lectures that Dr. Cady will present in Sao Paulo, Brazil, for Laboratorio Great Plains. In it, he reviews key concepts of integrative medicine, functional testing, and a rational style of thinking through a patient's problems down to the fundamental level. IgG food allergies, depression, low testosterone, and nutrient deficiencies are all covered
Hemp Oil: What Can It Do For You? Lebanon, TN 04 06 2018Louis Cady, MD
In this presentation, Dr. Cady reviews the peer-reviewed medical literature for the endocannibinoid system, the concept of endocannibinoid deficiency syndrome (now well established), and citations dealing with the multiplicity of health conditions for which a full spectrum hemp oil should be considered as a reasonable supportive strategy. The difference between the generic "CBD Oil" that is available at health food stores compared to the Zilis products is touched on. The Zilis products appear to have better absorbability, faster onset of action, and scientific studies elucidating the true duration of action of CBD levels in blood serum.
This presentation was given to a very appreciative audience at the Friendship Church in Lebanon, TN (a suburb of Nashville).
Natural Treatments for ADHD - December 7th, 2016 - Saint Marys HospitalLouis Cady, MD
This lecture, presented December 7th, 2016 for the Parent Support Group for children with ADHD and Sensory Processing Disorders, was presented at Saint Marys Hospital in Evansville, Indiana. In this one hour presentation, Dr. Cady broke down some of the alternative treatments for ADHD, grounded in the peer-reviewed literature, that do not involve the prescription of typical psychiatric medication for ADHD. He emphasized, natural, holistic treatments to treat deficiencies and restore balance of nutrients and specific essential fatty acids.
This brief webinar, a gift to the local Jewish community and Temple Adath B'Nai Israel here in Evansville, IN, reviews the tradition of mindfulness and the interdigitation of Buddhist practices with some Jewish traditions. Dr. Cady reviews the downstream effects of stress, how meditation and mindfulness are useful tools and techniques, and actually how to practice it. Multiple references without being complicated or overdone are provided.
How to Transition from Allopathic to Integrated Practice - IMM Brazil 2015Louis Cady, MD
In this lecture, Dr. Cady compares and contrasts the significance differences, both conceptually and practically, between the conventional practice of medicine and a more rational, functional, integrated approach. Tactical concepts and didactic tools to make the transition are reviewed.
The document summarizes a presentation on the holistic medicine approach to treating schizophrenia. It discusses the multiple domains affected by schizophrenia, including positive and negative symptoms, cognitive dysfunction, and social deficits. It reviews the etiology and pathogenesis of schizophrenia. It then presents a case study of a patient with schizophrenia who was treated holistically over many years with integrative testing to identify deficiencies and allergies, dietary changes, supplements, low dose lithium, and antifungals. The patient showed significant improvement with this approach.
Integrating the Functional, Psychodynamic, and Immunologic Matrix: New Advent...Louis Cady, MD
In this presentation (here represented in English before translation) Dr. Cady deconstructs the curious and sometimes perplexing manifestations of delayed sensitivity food allergy testing, supporting it with citations from the peer-reviewed medical literature and extensive bibliographic references. The importance of understanding the potential immunologic contribution to a patient's mental state is reviewed.
In his third of five lectures, Dr. Cady reviews the concepts of food allergy testing with IgG and IgE antibodies, traces the development of this body of knowledge from the 1960's, and reviews two illustrative cases.
"Killer Drugs & The Supplement Hall of Fame" - IMMH Brazil, 2015Louis Cady, MD
In this presentation, the third of three lectures Dr. Cady delivered in São Paulo, Brazil, Dr. Cady reviews the critical patterns of interactions with numerous frequently prescribed psychotropic medications (and others). Emphasis is given on how not to commit an obvious drug-drug interaction as well as avoiding more subtle ones. The focus then shifts to supplements: which ones are the best, which ones have mental health benefits, and how to avoid interactions between conventionally used supplements and psychiatric medications.
"Sexy" - part 3 of the CWI Lecture Series - June 2012f sss lectures series fo...Louis Cady, MD
The document discusses a talk given by Dr. Louis Cady on 21st century medicine, focusing on taking an integrated approach to optimizing hormone levels and overall health rather than just treating disease, with examples of evaluating and treating patients with hormone deficiencies even when conventional tests are considered "normal".
THE ENDOCANNABINOID SYSTEM - Cady Wellness InstituteLouis Cady, MD
This lecture, presented on February 2, 2018 at the Cady Wellness Institute in Newburgh, IN, represented Dr. Cady's review of the current peer-reviewed medical literature current as of that morning. The concepts of "endocannabinoids" vs. "phytocannabinoids" were reviewed. Themes in the medical literature were explored, including the relationship of the endocannabinoid system and CB! and CB2 receptors to modulate hippocampal neurogenesis, cause apoptosis in breast cancer cells, and many other interesting correlations. A careful review of legal vs illegal options for obtaining plant phytocannabinoids in the state of Indiana was emphasized.
New Adventures in Food Allergy Testing! 09 21 2013Louis Cady, MD
This document summarizes a presentation on new approaches to food allergy testing. It begins with the presenter's commercial disclosure statements listing companies he has received honoraria from or served on speaker's bureaus for. The presentation then covers the different immunoglobulin antibodies involved in food allergies, specifically IgE, IgG, and IgA. It discusses the mechanisms and downstream effects of these antibodies and food allergy reactions. Finally, it reviews several studies that have found associations between food allergies or sensitivities and conditions like attention-deficit/hyperactivity disorder, depression, anxiety, and autism spectrum disorders.
The document discusses the importance of sleep for health and provides tips for improving sleep. It notes that sleep between 11 PM - 1 AM is important for optimal functioning as it allows for deep sleep and REM sleep. It warns that lack of sleep can increase risks of various diseases and conditions. The document recommends getting checked for chiropractic subluxations, losing weight, avoiding stimulants before bed, keeping a regular sleep schedule and dark/cool bedroom to promote better sleep.
The document discusses the link between nutrition and mental health. It notes that recent studies have found no link between saturated fat intake and heart disease risk, contradicting conventional beliefs. Vitamins can be more effectively utilized by the body with help from saturated fats. The document also discusses the rise of mental illness diagnoses and prescription drug use in the US. It questions the effectiveness of psychiatric drugs and suggests addressing the nutritional deficiencies underlying mental health conditions.
The document discusses the history and effectiveness of measles vaccination programs in the United States and other countries. It notes that measles outbreaks were reported even in fully vaccinated populations in the early 1980s. Some studies found that measles vaccines were not provoking a proper immune response or providing long-lasting immunity. A CDC whistleblower later revealed that a 2004 study had found that the MMR vaccine was linked to a 340% increased risk of autism in African American boys under 3 years old, but this data was covered up by the CDC.
Diagnostic Testing and Treatment Adventures on Monday Morning: A Wrap-UpLouis Cady, MD
In this, the final lecture of the 2nd annual Integrated Medicine for Mental Health Conference held in beautiful Sedona, Arizona on September 17 - 18th, Dr. Cady summarizes four presenters, and 8 different lectures, into key concepts to be applied by the integrated and functional medicine practitioner on Monday a.m. This lecture aims to deal with the "My goodness, what do I do NOW?" question when a health care practitioner returns to his or her office and is overwhelmed with the amount of data heart at a conference such as this one.
The document discusses various topics related to the mind, including gratitude, mindfulness, neuroplasticity, epigenetics, the unconscious mind, mental practice, visualization, and the placebo effect. It provides examples of research showing how mental practices like meditation can positively impact the brain and biological systems, and discusses how experiences shape the structure of the brain through chemical changes and the wiring of neurons.
Taking NSAIDs like ibuprofen is associated with an increased risk of high blood pressure and congestive heart failure. The study found that NSAID use of 10 or more times per month was linked to over a 10-fold rise in heart failure risk. Regular NSAID use has also been tied to arthritis, gastrointestinal bleeding, skin conditions like toxic epidermal necrolysis, and certain cancers like pancreatic cancer in women. Chiropractic care and lifestyle changes like exercise, nutrition, rest, and stress management can help address the root causes of headaches and migraines as an alternative to toxic medications.
The document discusses 7 key health principles for kids:
1) Kids are born to be healthy without drugs or sickness unless caused by behaviors/environment.
2) Healthy food intake and avoiding sugars/preservatives is important to prevent obesity and related diseases.
3) Kids need daily outdoor activity and exercise to develop properly and maintain a healthy weight.
It also discusses risks of off-label drug use in children, medical errors as a cause of children's deaths, adverse drug reactions, and benefits of chiropractic care for children's health and development. The document advocates for natural health approaches over excessive drug use for kids.
This presentation was designed as a destination for little-known, cutting-edge — and sometimes unconventional — information that can revolutionize people’s health… or even save lives. It emerged as an offshoot of the highly popular eBook “Where Science Meets The Cure”, which is read by hundreds of thousands of subscribers from every country in the world every single week.
Potential nutraceuticals and their functionHazrat Ali
The document discusses potential nutraceuticals found in common foods in Bangladesh. It begins by defining nutraceuticals and their potential health benefits. One nutraceutical discussed in detail is capsaicin, the active component in chili peppers. Capsaicin is found in large quantities in chili peppers and has several potential health benefits including cancer treatment, decreasing cluster headaches, pain relief, treating psoriasis, aiding diabetes management, and lowering blood pressure. The document provides sources and evidence from studies on the health effects of capsaicin.
Introduction to Integrative Medicine for Mental HealthLouis Cady, MD
This is the first of three lectures that Dr. Cady will present in Sao Paulo, Brazil, for Laboratorio Great Plains. In it, he reviews key concepts of integrative medicine, functional testing, and a rational style of thinking through a patient's problems down to the fundamental level. IgG food allergies, depression, low testosterone, and nutrient deficiencies are all covered
Hemp Oil: What Can It Do For You? Lebanon, TN 04 06 2018Louis Cady, MD
In this presentation, Dr. Cady reviews the peer-reviewed medical literature for the endocannibinoid system, the concept of endocannibinoid deficiency syndrome (now well established), and citations dealing with the multiplicity of health conditions for which a full spectrum hemp oil should be considered as a reasonable supportive strategy. The difference between the generic "CBD Oil" that is available at health food stores compared to the Zilis products is touched on. The Zilis products appear to have better absorbability, faster onset of action, and scientific studies elucidating the true duration of action of CBD levels in blood serum.
This presentation was given to a very appreciative audience at the Friendship Church in Lebanon, TN (a suburb of Nashville).
Natural Treatments for ADHD - December 7th, 2016 - Saint Marys HospitalLouis Cady, MD
This lecture, presented December 7th, 2016 for the Parent Support Group for children with ADHD and Sensory Processing Disorders, was presented at Saint Marys Hospital in Evansville, Indiana. In this one hour presentation, Dr. Cady broke down some of the alternative treatments for ADHD, grounded in the peer-reviewed literature, that do not involve the prescription of typical psychiatric medication for ADHD. He emphasized, natural, holistic treatments to treat deficiencies and restore balance of nutrients and specific essential fatty acids.
This brief webinar, a gift to the local Jewish community and Temple Adath B'Nai Israel here in Evansville, IN, reviews the tradition of mindfulness and the interdigitation of Buddhist practices with some Jewish traditions. Dr. Cady reviews the downstream effects of stress, how meditation and mindfulness are useful tools and techniques, and actually how to practice it. Multiple references without being complicated or overdone are provided.
How to Transition from Allopathic to Integrated Practice - IMM Brazil 2015Louis Cady, MD
In this lecture, Dr. Cady compares and contrasts the significance differences, both conceptually and practically, between the conventional practice of medicine and a more rational, functional, integrated approach. Tactical concepts and didactic tools to make the transition are reviewed.
The document summarizes a presentation on the holistic medicine approach to treating schizophrenia. It discusses the multiple domains affected by schizophrenia, including positive and negative symptoms, cognitive dysfunction, and social deficits. It reviews the etiology and pathogenesis of schizophrenia. It then presents a case study of a patient with schizophrenia who was treated holistically over many years with integrative testing to identify deficiencies and allergies, dietary changes, supplements, low dose lithium, and antifungals. The patient showed significant improvement with this approach.
Integrating the Functional, Psychodynamic, and Immunologic Matrix: New Advent...Louis Cady, MD
In this presentation (here represented in English before translation) Dr. Cady deconstructs the curious and sometimes perplexing manifestations of delayed sensitivity food allergy testing, supporting it with citations from the peer-reviewed medical literature and extensive bibliographic references. The importance of understanding the potential immunologic contribution to a patient's mental state is reviewed.
In his third of five lectures, Dr. Cady reviews the concepts of food allergy testing with IgG and IgE antibodies, traces the development of this body of knowledge from the 1960's, and reviews two illustrative cases.
"Killer Drugs & The Supplement Hall of Fame" - IMMH Brazil, 2015Louis Cady, MD
In this presentation, the third of three lectures Dr. Cady delivered in São Paulo, Brazil, Dr. Cady reviews the critical patterns of interactions with numerous frequently prescribed psychotropic medications (and others). Emphasis is given on how not to commit an obvious drug-drug interaction as well as avoiding more subtle ones. The focus then shifts to supplements: which ones are the best, which ones have mental health benefits, and how to avoid interactions between conventionally used supplements and psychiatric medications.
"Sexy" - part 3 of the CWI Lecture Series - June 2012f sss lectures series fo...Louis Cady, MD
The document discusses a talk given by Dr. Louis Cady on 21st century medicine, focusing on taking an integrated approach to optimizing hormone levels and overall health rather than just treating disease, with examples of evaluating and treating patients with hormone deficiencies even when conventional tests are considered "normal".
THE ENDOCANNABINOID SYSTEM - Cady Wellness InstituteLouis Cady, MD
This lecture, presented on February 2, 2018 at the Cady Wellness Institute in Newburgh, IN, represented Dr. Cady's review of the current peer-reviewed medical literature current as of that morning. The concepts of "endocannabinoids" vs. "phytocannabinoids" were reviewed. Themes in the medical literature were explored, including the relationship of the endocannabinoid system and CB! and CB2 receptors to modulate hippocampal neurogenesis, cause apoptosis in breast cancer cells, and many other interesting correlations. A careful review of legal vs illegal options for obtaining plant phytocannabinoids in the state of Indiana was emphasized.
New Adventures in Food Allergy Testing! 09 21 2013Louis Cady, MD
This document summarizes a presentation on new approaches to food allergy testing. It begins with the presenter's commercial disclosure statements listing companies he has received honoraria from or served on speaker's bureaus for. The presentation then covers the different immunoglobulin antibodies involved in food allergies, specifically IgE, IgG, and IgA. It discusses the mechanisms and downstream effects of these antibodies and food allergy reactions. Finally, it reviews several studies that have found associations between food allergies or sensitivities and conditions like attention-deficit/hyperactivity disorder, depression, anxiety, and autism spectrum disorders.
The document discusses the importance of sleep for health and provides tips for improving sleep. It notes that sleep between 11 PM - 1 AM is important for optimal functioning as it allows for deep sleep and REM sleep. It warns that lack of sleep can increase risks of various diseases and conditions. The document recommends getting checked for chiropractic subluxations, losing weight, avoiding stimulants before bed, keeping a regular sleep schedule and dark/cool bedroom to promote better sleep.
The document discusses the link between nutrition and mental health. It notes that recent studies have found no link between saturated fat intake and heart disease risk, contradicting conventional beliefs. Vitamins can be more effectively utilized by the body with help from saturated fats. The document also discusses the rise of mental illness diagnoses and prescription drug use in the US. It questions the effectiveness of psychiatric drugs and suggests addressing the nutritional deficiencies underlying mental health conditions.
The document discusses the history and effectiveness of measles vaccination programs in the United States and other countries. It notes that measles outbreaks were reported even in fully vaccinated populations in the early 1980s. Some studies found that measles vaccines were not provoking a proper immune response or providing long-lasting immunity. A CDC whistleblower later revealed that a 2004 study had found that the MMR vaccine was linked to a 340% increased risk of autism in African American boys under 3 years old, but this data was covered up by the CDC.
Diagnostic Testing and Treatment Adventures on Monday Morning: A Wrap-UpLouis Cady, MD
In this, the final lecture of the 2nd annual Integrated Medicine for Mental Health Conference held in beautiful Sedona, Arizona on September 17 - 18th, Dr. Cady summarizes four presenters, and 8 different lectures, into key concepts to be applied by the integrated and functional medicine practitioner on Monday a.m. This lecture aims to deal with the "My goodness, what do I do NOW?" question when a health care practitioner returns to his or her office and is overwhelmed with the amount of data heart at a conference such as this one.
The document discusses various topics related to the mind, including gratitude, mindfulness, neuroplasticity, epigenetics, the unconscious mind, mental practice, visualization, and the placebo effect. It provides examples of research showing how mental practices like meditation can positively impact the brain and biological systems, and discusses how experiences shape the structure of the brain through chemical changes and the wiring of neurons.
Taking NSAIDs like ibuprofen is associated with an increased risk of high blood pressure and congestive heart failure. The study found that NSAID use of 10 or more times per month was linked to over a 10-fold rise in heart failure risk. Regular NSAID use has also been tied to arthritis, gastrointestinal bleeding, skin conditions like toxic epidermal necrolysis, and certain cancers like pancreatic cancer in women. Chiropractic care and lifestyle changes like exercise, nutrition, rest, and stress management can help address the root causes of headaches and migraines as an alternative to toxic medications.
The document discusses 7 key health principles for kids:
1) Kids are born to be healthy without drugs or sickness unless caused by behaviors/environment.
2) Healthy food intake and avoiding sugars/preservatives is important to prevent obesity and related diseases.
3) Kids need daily outdoor activity and exercise to develop properly and maintain a healthy weight.
It also discusses risks of off-label drug use in children, medical errors as a cause of children's deaths, adverse drug reactions, and benefits of chiropractic care for children's health and development. The document advocates for natural health approaches over excessive drug use for kids.
This presentation was designed as a destination for little-known, cutting-edge — and sometimes unconventional — information that can revolutionize people’s health… or even save lives. It emerged as an offshoot of the highly popular eBook “Where Science Meets The Cure”, which is read by hundreds of thousands of subscribers from every country in the world every single week.
Potential nutraceuticals and their functionHazrat Ali
The document discusses potential nutraceuticals found in common foods in Bangladesh. It begins by defining nutraceuticals and their potential health benefits. One nutraceutical discussed in detail is capsaicin, the active component in chili peppers. Capsaicin is found in large quantities in chili peppers and has several potential health benefits including cancer treatment, decreasing cluster headaches, pain relief, treating psoriasis, aiding diabetes management, and lowering blood pressure. The document provides sources and evidence from studies on the health effects of capsaicin.
This document summarizes a presentation about the company LifeVantage and their flagship product Protandim. Protandim is a dietary supplement that was shown in clinical studies to reduce oxidative stress by an average of 40% after 30 days of use. It works by activating the Nrf2 pathway and increasing the body's natural antioxidant production. The presentation outlines the science behind oxidative stress and Protandim's mechanism of action. It also discusses LifeVantage's business model and compensation plan for distributors.
Ngayon, Samantalahin ang Pagkakataong Ito !
Nais mo Bang Maibalik Ang Mga Panahon o Oras na Nakalipas Sa Pamamagitan Lamang ng Ilang Tabletas ?
Seize this Moment! ! Nais mo Bang Maibalik Ang Panahon o na Nakalipas?
/Edgardo Gonzalez
1-5123820848
egonzalez@vivagreenindustries.com
egonzalez@elitegloballeadership
The document discusses memantine, a drug approved by the FDA to treat symptoms of Alzheimer's disease. Researchers reviewed studies on memantine's effectiveness in patients with mild Alzheimer's. They found that memantine was no more effective than a placebo at treating the disease. The document also provides information on the progressive stages of Alzheimer's disease and generic drug brands approved to treat symptoms.
The powerpoint presentation delivered LIVE at CWI 4/15/2010 by Louis B. Cady, MD, Founder and CEO of Cady Wellness Institute, on the topic of Max GXL, glutathione augmentation, and vitamin supplementation.
Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. Here in this document, you will everything about CBD and CBD oil benefits.
HOW TO SAVE MONEY ON YOUR HEALTHCARE: An Integrative Medicine ApproachLouis Cady, MD
In this webinar, the fourth in a series of five from Dr. Louis Cady and the Cady Wellness Institute, we focus on the actual dollars and cents of health care expenditures, and the societal and PERSONAL costs of poor health maintenance behavior. We examine the essentially passive US medical system, that would rather drug a symptom than fix the underlying problem.
Great attention is paid on not shaming the patient or the doctors as they exist in the current system. Both groups "do not know what they do not know." Confirmation bias is rampant.
This webinar points the way to living a more vital, energetic life, with a minimum of cost, grief, and misery.
This document summarizes a workshop on developing clinical care guidelines for growth hormone treatment in Prader-Willi syndrome. The workshop brought together over 40 experts, including endocrinologists, geneticists, clinicians with an interest in growth hormone research, patient advocates, and methodologists. It utilized a multi-criteria decision analysis framework to develop the guidelines, taking into account scientific evidence, disease impact, safety, and other criteria. The goal was to produce consensus guidelines that integrated evidence, values, and ethics to guide policy and clinical practice around this complex treatment decision.
Ganotherapy is a line of thought consisting of 4 observation theories to explain how Ganoderma lucidum supports the human body's ability to overcome health problems. The theories are: 1) Health problems arise from toxins and imbalance, 2) Ganoderma supports the body to address problems itself, 3) Ailment reflections occur as the body discharges toxins and balances itself, not because of Ganoderma, and 4) There are recommended dosages to provide optimum support to the body. DXN products like Ganoderma, Spirulina, and others provide nutrients and support these health processes in natural ways.
Drug repurposing involves finding new uses for existing drugs to treat rare diseases. It has advantages over developing new drugs including being faster, cheaper, and leveraging existing safety and use data. Opportunities for repurposing can be identified through screening compound libraries, literature mining, and 'omics approaches. A example is using the epilepsy drug sodium valproate identified from screening as a potential treatment for Wolfram syndrome, which is now in clinical trials.
The rapid cure using Transfer Factor Science.
Team 4Life is a group of world-renowned athletes who excel in their disciplines and endorse 4Life Transfer Factor® products.
Global Team 4Life athletes include World Series starting pitcher Orlando Hernández (“El Duque”), Denver Broncos Offensive Guard Manuel "Manny" Ramirez, Super Bowl Champion Sam Madison, 2010 Baseball World Series Most Valuable Player (MVP) Edgar Rentería, World Golf Hall of Famer Johnny Miller, Ian Baker-Finch, winner on all-four major tours, world-class powerlifter Brady Stewart, Kona Ironman Triathlete Glenn Dobson, Karate World Champion Yohana Sánchez, Freestyle Aerialist Alexa Devereaux, and professional golfers Paosingh Nissaisook and Thitipong Na Songkhla in the Eastern Hemisphere and triathletes Ty Hopkins and Modesto Duran Riquelme in the Western Hemisphere.
The document discusses drug repurposing for rare diseases. Drug repurposing involves finding new uses for existing drugs to treat different patient populations. The document provides examples of repurposing drugs to treat rare conditions like Wolfram syndrome and CDKL5. It also discusses using 'omics data to identify repurposing opportunities and describes a potential social impact bond model to fund repurposing clinical trials through healthcare savings.
This document provides an overview of pharmacovigilance and the Pharmacovigilance Program of India (PvPI). It defines pharmacovigilance as the science of detecting, assessing, understanding, and preventing adverse effects of medicines. The document outlines the historical events that led to the development of pharmacovigilance, including the sulfanilamide and thalidomide disasters. It describes the vision, mission, aims, and objectives of PvPI in India to improve patient safety related to medicine use. Key aspects of PvPI covered include adverse drug reaction reporting processes and the expansion of PvPI to include additional medical areas over time.
Similar to Medical Discussion of the Endocannabinoid System (18)
SEND IN THE SHRINKS - 2009 Oliver CME seminarLouis Cady, MD
This one was fun.
I was invited by Dr. Randalll Oliver, MD, Founder of the Oliver Heachache and Pain Clinic in Evansville, to present to an audience of primary care practitioners about how to use pysychiatric mediations ("psychopharmacology") in clinical practice.
Along the way, I covered, ADHD and treatments, depression, anxiety, erectile dysfunction, hypoadrenia, and even touched on hypothyroidism. Although this presentation was in 2009, all of the drugs covered are stills in use, and, at times.... stupidly.
This presentation deconstructs the intricacies of selecting and antidepressant, particularly in the SSRI class.
What is the nature of QUALITY in medicine -for ASQ 11 14 2023.pptLouis Cady, MD
In this presentation, Dr. Cady deconstructs the tensions and stressors on both patients and health care providers in today's system.
This presentation reviews checklists foe liminating mistakes, the actual number of mistakes that are being made in medical practice, and what patients and their loved ones can do for self protection.
This isn't a "bash the doctor" presentation. It's a thoughtful, careful exploration of stresses and ramifications to the current US healthcare system.
This document provides information about a presentation given by Dr. Louis B. Cady on transcranial magnetic stimulation (TMS) as a treatment for depression. It begins with Dr. Cady's credentials and commercial disclosure stating he has received honoraria from several companies but that this presentation is not being underwritten by any company. The presentation then covers how TMS works, its safety and effectiveness compared to antidepressant medications and electroconvulsive therapy (ECT), and its inclusion in treatment guidelines for depression.
Hormones and Mental Health - Thyroid and Testosterone.pptxLouis Cady, MD
In this presentation for the Psychiatry Redefined program, Dr.
Cady breaks down and deconstructs the accepted, unthinking, "practice guideline based" notions of thyroid and tesotsterone, with there seemingly "normal" levels and dosing, versus what the actual peer reviewed medical literature says. In this presentation, do use of all forms of thyroid, and all forms of testosterone are reviewed. The idiocy of "T4 only treatment" is covered. The use of T4, T3, a combination of T4 and T3, and all of the porcine and compounded products is review.
In terms of testosterone, dr. Katie reviews the concept of "do you want to be optimal or do you want to be normal." He notes that it is "normal" for oil in cars to deteriorate and break down with age. It's also "normal" for men's and women's testosterone (as well as thyroid) to go down with age. The question is, "do we want to do anything about it?"
Logical ways of intervening in both the thyroid and female and male gonadal axes are covered. There is scrupulous attention paid to the thyroid hormone pathways, and the relevance of reverse T3 versus free T3. Similarly, in terms of women, the downstream effect of estradiol coming from testosterone is also reviewed.
The Moral Imperative of Integrative Medicine 2022.pptLouis Cady, MD
The document discusses the case of a 16-year-old teenager with a long history of treatment-resistant depression and anxiety. Previous medication trials with SSRIs, SNRIs, atypical antipsychotics, and lamotrigine had failed to provide sustained relief. Upon further evaluation, the doctor found potential contributing factors including an undiagnosed MTHFR gene mutation and hormonal imbalances. The doctor adjusted the teenager's supplements and medications, focusing on addressing the underlying functional issues. At follow-up several months later, the teenager reported significantly improved mood with only brief periods of low mood, though menstrual irregularities persisted.
CORONOFOBIA - Passos práticos para equilibrar as defesas do corpo e da menteLouis Cady, MD
Esta palestra, apresentada em 29 de maio de 2021 para o Congresso de Medicina Integrativa para a Saúde Mental 2020, promovido pelo Laboratório Great Plains no Brasil, enfocou coisas simples e de bom senso que os pacientes (e seus médicos) podem fazer para se manter seguros e viver durante o Pandemia do covid.
Os seguintes conceitos holísticos foram revisados:
- sono adequado e por que é tão importante;
- o uso de melatonina, cientificamente validada como tendo atividade antiviral (referências citadas);
- a importância de diminuir o estresse e técnicas para fazê-lo;
- a necessidade de "comer frutas e vegetais" como sua mãe e sua avó ensinaram devido à ingestão de carotenóides e antioxidantes ((referências citadas);
- o uso adequado de suplementos vitamínicos / nutricionais (referências citadas).
O foco desta apresentação não foram medidas heróicas para salvar vidas na unidade de terapia intensiva para pacientes gravemente enfermos com COVID, mas, sim, técnicas de bom senso, práticas, baratas e (em alguns casos) GRATUITAS para melhorar você e seus pacientes 'saúde e resistência às doenças.
THE MORAL IMPERATIVE OF INTEGRATIVE MEDICINE - O IMPERATIVO MORAL DA MEDICINA...Louis Cady, MD
Neste programa, o Dr. Cady baseia-se em uma série de casos clínicos para ilustrar a necessidade absoluta e moral do tratamento de precisão de nossos pacientes com todas as ferramentas disponíveis para uso por meio da medicina integrativa.
O uso de testes de polimorfismo MTHFR, testes convencionais e laboratoriais e testes farmacogenômicos foram revisados.
Os casos apresentados ilustram a trágica dificuldade de um menino com deficiência de MTHFR que estava prestes a desviar sua vida; um paciente esquizofrênico com vários problemas de medicina funcional que precisavam ser resolvidos (levedura, glúten, sensibilidade alimentar de IgG); uma estudante universitária a quem foi dito "não há nada de errado com você; seus laboratórios estão bem", embora ela tenha manifestado todos os sintomas relevantes de hipotireoidismo; e um CEO do sexo masculino de 42 anos que estava "tão cansado que parecia morrer" e que, na verdade, estava funcionalmente com pouco testosterona. O último caso revisado foi de um adorável garotinho que tinha autismo e foi recuperado por meio de uma abordagem focada e intensa de medicina integrativa.
Dr. Cady deconstructs some the medical literature about the use of nutrients - and the evidence of what happens in the presence of their insufficiency. Everything for decreased viral replication to decrease brain shrinkage is covered. The role of antioxidant and carotenoids, measured by the Pharmanex Biophotonic Scanner, is reviewed.
Please note - there is no representation that any nutrient or supplement can treat, prevent, mitigate, or cure any medical condition. It does seem, however, upon reflecting on the medical literature, that there seems to be a lot of evidence for therapeutic effect in the presence of good levels of nutrient, and harm to patients if they have insufficient levels.
Webinar 5: Designing Your Future: WHAT'S COMING NEXT?Louis Cady, MD
In this capstone webinar presentation, closing out Dr. Cady's series on dealing with COVID 19, he turns his attention to a nunmber of interesting thems:
- what's the REAL case fatality rate of COVID 19
- How is it likely that society will reopen?
- What's going to happen in education and medicine?
- What's going to happen when the robots and AI arrive?
- What's the future going to be out 500 years?
HOW TO COPE WITH THE PSYCHOLOGICAL IMPACT OF COVID 19 AND SOCIAL DISTANCINGis...Louis Cady, MD
In this presentation, Dr. Cady will review:
- What did Sparky learn about not being an emotional support animal?
- "Do it to yourself psychotherapy." Learn the following:
- What are the wrong - and the RIGHT ways of any sort of "behavioral therapy"?
- How to use a journal to think RATIONALLY and “get out of your head.”
- How to get out of your HEAD and into your LIFE.
- We'll cover all 10 of David Burns’ cognitive distortions, customized and gift-wrapped for dealing with COVID 19.
- We will cover actionable examples of how to reprogram yourself.
We will review What are the 3 P's of Positive Psychology and Learned Optimism?
The Cady 5 "5P’s” and “How to shrink yourself."
Can we find the GOOD in COVID?
This presentation is meant to be provocative and to challenge you mentally, intellectually, and emotionally. Some of the great thinkers and exemplars of human performance and possibility are featured.
BOOSTING YOUR IMMUNITY During the COVID 19 PandemicLouis Cady, MD
In this presentation, presented as a live webinar on Monday, April 27th, Dr. Louis Cady of the Cady Wellness Institute reviewed practical, common-sense things that can be done to boost your immunity, with documentation from the peer-reviewed medical literature. Dr. Cady also reviews supplements and nutrients that are established in the peer-reviewed medical literature as having antiviral capabilities. These include Vitamins C,D, and E, Zinc, carotenoids and antioxidants, probiotics, the reishi mushroom, elderberry, cannabidiol (CBD - not marijuana or weed!).
Points presented are scrupulously documented from the medical literature. This presentation does not guarantee or represent that using ANY of these nutrients will "keep you from getting infected or dying" from COVID 19. They are presented for your thoughtful consideration.
Tratamento holistica de ezschizophrenia - São Paulo, Brazil April 20, 2019Louis Cady, MD
Esta é a versão em inglês da apresentação do Dr. Cady feita na UNIP (Campus Paraiso - São Paulo, SP Brasil) para o Congresso de Saúde Mental de 2019 (Conferência sobre Saúde Mental). Foi entregue em 20 de abril de 2019.
Nesta apresentação, o Dr. Cady analisa brevemente a história da esquizofrenia, a falha do bloqueio do receptor de dopamina D2 como uma cura universal na esquizofrenia, e várias intervenções holísticas que podem impactar forte e positivamente os sintomas da esquizofrenia. Incluídos na pesquisa do Dr. Cady estavam o papel dos ácidos graxos essenciais, deficiências nutricionais (particularmente vitaminas do complexo B), o perigo de supercrescimento da cândida, testes farmacogenômicos, polimorfismos da MTHFR e muito mais.
Foi uma honra e um privilégio entregar esta apresentação em
São Paulo.
Para mais informações no Brasil sobre este tema, ou para solicitar uma gravação em vídeo / áudio da conferência, entre em contato com Luiz Dias do Laboratório Grandes Planícies no Brasil.
Slides, até o apêndice, são traduzidos por Luiz Dias.
Natural Treatments for ADHD - April 11, 2018Louis Cady, MD
This presentation will be delivered April 11, 2018 on recorded webinar for the Autism Global Conference. It was my pleasure to prepare and present this lecture (in webinar form), outlining a coherent philosophy of finding biological underpinnings that can cause or contribute to, or exacerbate, mental dysfunction. In the case of this presentation, the question is "How much of ADHD symptomatology is caused by a lack of a good medication, or, rather, lack of a coherent strategy for finding and fixing underlying biological abnormalities?"
Those biological abnormalities in this presentation include MTHFR polymorphisms, COMT polymorphisms, elemental deficiencies (lithium, magnesium, zinc, iron, and copper), essential fatty acid deficiencies, the confound of high fructose corn syrup, and many others.
Rational strategies for nutraceutical intervention are reviewed.
A abordagem da Medicina Integrativa para o Tratamento da EsquizofreniaLouis Cady, MD
This is the presentation that Dr. Cady gave in São Paulo, Brazil, in October of 2017 on the integrtive treatment of schizophrenia. The one in English is already posted. My thanks to Luiz Dias, of Laboratorio Great Plans in Brazil, for his impeccable translation.
Endocannabinoid System - Literature ReviewLouis Cady, MD
In this brief review of the literature, Dr. Louis Cady of the Cady Wellness Institute reviews the endocannabinoid system and the role it plays in bridging the connection between mind and body, modulating anxiety, inflammation, memory and other physiological processes. Nothing in this presentation suggests that any of the products mentioned are appropriate for the treatment, remediation, cure, or prevention of any disease or illness. It does appear, however, that this natural, indwelling, genetically passed down endocannabinoid system may have major implications for holistic physicians and health care practitioners, and for the patients that they serve.
The Integrative Medicine Treatment of SchizophreniaLouis Cady, MD
This is the third of three lectures that Dr. Cady did in Sao Paulo, Brazil, for Laboratorio Great Plains. Dr. Cady dispenses with the "Dopamine hypothesis of schizophrenia" quickly, and notes that the most powerful drug for schizophrenia, clozapine, is actually only a weak blocker at that receptor. Using the concepts of Dale Bredesen, MD, Dr. Cady advances the idea that there is no "one magic bullet" approach to the treatment of schizophrenia, but that, rather, multiple possibile causes of schizophrenia exist, multiple nutritional laboratory values exist, multiple other physiological perturbations exist (including gluten sensitivyt), and that the thoughtful practitioner's approach should be to attempt to identify, integrate, and address all possible causes and exacerbating influences on the causes, and treatments of schizophrenia. Obviously, this is not a comprehensive treatment on the subject - which would take days - but does scratch the surface at other ways to look at schizophrenia and approach its treatment.
This is the second of three lectures Dr. Cady gave in Brazil. This is an update his previous thyroid talk, focusing more particularly on mental effects and the assessment of thyroid axes, and thyroid use, in mental healthj
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...rightmanforbloodline
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Versio
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Version
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Version
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
share - Lions, tigers, AI and health misinformation, oh my!.pptx
Medical Discussion of the Endocannabinoid System
1. Louis B. Cady, MD, FAPA – CEO & Founder – Cady Wellness InstituteLouis B. Cady, MD, FAPA – CEO & Founder – Cady Wellness Institute
Adjunct Clinical Lecturer – Indiana University School of Medicine
Department of Psychiatry
Functional & Integrative Medicine – Evansville, Indiana
Hemp Oil: What Can It Do For You?
August 22, 2018
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
2. A note for the viewer – please read carefully.
• The slide presentation in this “deck” was presented as an educational
lecture on April 6, 2018 in Evansville, Indiana. I have had several
requests for the slides.
• All slides in this deck should be looked at as informational ONLY. Any
benefit for the use of these products is ONLY due to their ability to
support the structure and function of the human body.
• This deck may not be downloaded, stored, or modified in any way
whatsoever.
This slide deck is not approved by the FDA. No Zilis product can be represented
to treat, prevent, mitigate, or cure any disease. They are used ONLY for the
structure and support of the body – specifically, the endocannabinoid system.
3. Getting high on cannabis makes you less likely to work hard for
money, study says – The Independent Sept 1, 2016
So why did God put a receptor for THC in our brains?
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
4. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
5. Eliassen AH, et al. Circulating Carotenoids and Risk of Breast Cancer: Pooled Analysis of Eight
Prospective Studies. J Natl Cancer Inst. 2012 Dec 19;104(24):1905-16. doi: 10.1093/jnci/djs461.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
6. MVI – supports the structure & function
• B12 - 1,000% (as 60 MICROgrams cyanocobalamin)
• B6 - 500%
• Folic acid/folate - 150%
• Magnesium 76% (as 300 Mg amino acid chelate)
• Zinc 100% (15 mg as zinc chelate)
• Selenium 200% (L-selenomethionine & NaSeO3)
• Iodine 76%
• Chromium 166% blood sugar control!
• Vitamin C 834%
• Vitamin A 300% (83% as Beta carotene and plant extracts
• Vitamin E 666% (200 IU Vitamin E, d-alpha tocopherol, tocotrienols
HOMOCYSTEINE LOWERING
MOOD IMPROVING
Testosterone raising!
Boosts thyroid production!
7.
8. • Raphael Mechoulam, Ph.D.
• Professor of Medicinal Chemistry at
Hebrew University of Jerusalem
• He/research group chemically
synthesized all of the major plant
cannabinoids ( delta-9TCH,
cannabidiol, cannabigerol
• First isolation of the first
endocannabinoid – Anandamide
• 2-AG was soon discovered by
Shimon Ben-Shabat, one of his Ph.D.
students.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They are
used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
9. History of Cannabidiol, Endocannabinoid
system, etc.
• Hashish I. The structure of cannabidiol –
Mechoulam, Shvo, 1963
• Hashish. IV. The isolation and structure of
cannabinolic and cannabigerolic acids. 1964
• Delta-9 THC was synthesized. 1965
• “The effect of cannabidiol on mouse hepatic
microsomal anandamide metabolism. 1993 – first
paper on “endocannabinoid system.”This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
10. “Clinical endocannabinoid deficiency (CECD) can this
concept explain therapeutic benefits of cannabis in
migraine, fibromyalgia, IBS, and other treatment resistant
conditions?”
• Yes!
• First published by EB Russo in 2004
• “Migraine, fibromyalgia, IBS, and related
conditions…suggest an underlying clinical
endocannabinoid deficiency that may be suitably
treated with cannabinoid medicines.”
Neuro Endocrinol Lett. 2004 Feb-Apr;25(1-2):31-9.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
11. 4,382 results – Feb 2, 2018 6:26 am4,382 results – Feb 2, 2018 6:26 am
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
12. 4,591 results – August 19, 20184,591 results – August 19, 2018
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
13. Study: evaluate CB1 ligands + other agents “that possess
antidepressant potential.”
CONCLUSIONS: “The simultaneous modulation of the
cannabinoid system and supplementation of magnesium
or zinc produce at least additive antidepressant-like
effect.”
Study: evaluate CB1 ligands + other agents “that possess
antidepressant potential.”
CONCLUSIONS: “The simultaneous modulation of the
cannabinoid system and supplementation of magnesium
or zinc produce at least additive antidepressant-like
effect.”This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
14. The results of the present study suggest that CB1r,
CB2r, and MAGL are closely related to the
neuropathological processes of PD. Therefore, the
pharmacological modulation of these targets
could represent a new potential therapeutic tool
for the management of PD.
The results of the present study suggest that CB1r,
CB2r, and MAGL are closely related to the
neuropathological processes of PD. Therefore, the
pharmacological modulation of these targets
could represent a new potential therapeutic tool
for the management of PD.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
15. Smith SC. Neuro Endocrinol Lett.
2014;35(3):198-201.
Smith SC. Neuro Endocrinol Lett.
2014;35(3):198-201.
CONCLUSION: Subsequent research has confirmed that underlying
endocannabinoid deficiencies indeed play a role in migraine,
fibromyalgia, irritable bowel syndrome and a growing list of other
medical conditions. Clinical experience is bearing this out. Further
research and especially, clinical trials will further demonstrate the
usefulness of medical cannabis. As legal barriers fall and scientific
bias fades this will become more apparent.
CONCLUSION: Subsequent research has confirmed that underlying
endocannabinoid deficiencies indeed play a role in migraine,
fibromyalgia, irritable bowel syndrome and a growing list of other
medical conditions. Clinical experience is bearing this out. Further
research and especially, clinical trials will further demonstrate the
usefulness of medical cannabis. As legal barriers fall and scientific
bias fades this will become more apparent.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
16. SEVERAL INTERVENTIONS UPREGULATE THE
ECS SYSTEM:
•Analgesics, anti-inflammatories
•Antidepressants, antipsychotics, anxiolytics, anticonvulsants
•Massage and manipulation
•Acupuncture
•Dietary supplements and herbal medicines.
SEVERAL INTERVENTIONS UPREGULATE THE
ECS SYSTEM:
•Analgesics, anti-inflammatories
•Antidepressants, antipsychotics, anxiolytics, anticonvulsants
•Massage and manipulation
•Acupuncture
•Dietary supplements and herbal medicines.
McPartland JM et al. PLoS One. 2014, Mar
12;9(3):e89566
McPartland JM et al. PLoS One. 2014, Mar
12;9(3):e89566
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
17. Way back in April 14-15, 1912
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
18. Purdue University & Mr. Fred A. Miler, botanist to Eli Lilly
& Co. partner for “medicinal extract of Hemp (CBD)
Research,” c. 1912-13
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
19. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
20. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
21. Hemp
• One of the oldest known cultivated plants
• 12,000 years of usage
• Used for clothes, soap and rope
• Has a wide array of nutrients in
it of almost all sources.
• Medicinal use: 6,000 years
• 3rd
most prescribed medicinal agent for 60 years
prior to its prohibition in 1937This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
22. Cannabis SATIVA -
HEMP
Cannabis SATIVA - HEMP Cannabis SATIVA
subspecies INDICA
AND SEX DOESN’T MATTER!!
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
23. Endogenous cannabinoids
• Synthesized in OUR body: ENDOcannabinoids
– 2-AG (2-arachidonylgylerol)
– Anadamide (N-arachidonoylethanolamine “AEA”)
• These are fatty acid neurotransmitters
• 2-AG – most abundant endocannabinoid in the
body
• Regulates appetite, immune function, pain signals,
energy storage, among others.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
24. Endocannibinoid system – the body’s
primary tool of homeostasis
• Most significant neurotransmitter system in
the body
• Regulates & balances:
– Nerve function, stress recovery,
inflammation levels, immune function,
energy intake and storage, cell life-
cycles/apoptosis/reproduction,
circulatory system
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
25. The endocanninoid receptors by the
numbers…• CB1
– Brain spinal cord, reproductive & connective tissues
• CB2
– Modulates immune system. Found on spleen, tonsils,
thymus, all white blood cells (receptors)
• T cells, B-eta cells, macrophages
• GPR55 – linked to bone development and cancer
cell proliferation
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
26. Endocannabinoids 101
• YOU make ENDO-cannabinoids
– 2-AG (2 arachidonoylglycerol)
• Most abundant
• Regulates appetite, immune function, pain signals, energy
storage.
– Anandamide (N-arachidonoylethanolamine “AEA”)
• HEMP plant makes PHYTO-cannabinoids
– Interacts well with human CB receptors.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
27. Anandamide
• From Sanskrit for “bliss” or “happiness.”
• Regulates pleasurable activities – food intake,
reproduction, sleep, and pain relief
• Found in mother’s milk, chocolate, and release
during ovulation
• Produced during meditation, yoga, and causes
RUNNER’S HIGH.
• A “bridge” between mind and body.This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
28. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
29. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
30. • Circulating eCB’s in humans, dogs, and ferrets measured before and
after treadmill exercise.
• “We show that humans and dogs shaire significantly increased
exercise-induced eCB signaling following high-intensity endurance
running.
• eCB’s are “a neurobiological reward for endurance exercise.”
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
31. CECD: Clinical endocannabinoid
deficiency
• Implicated in many hard-to-treat disease
states:
– Fibromyalgia
– Chronic migraines
– Depression/anxiety
– Irritable bowel syndrome Russo EB. Neuro End Lett
2008 April; 29(2): 192-200.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
32. 60 citations 08 19 2018
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
33. 57 citations 04/06/ 2017“Deficits in signaling mediated by the
endocannabinoid 2-AG have been reported in
mouse models of autism spectrum disorder.”
“Deficits in signaling mediated by the
endocannabinoid 2-AG have been reported in
mouse models of autism spectrum disorder.”
“Deficits in social interaction, excessive grooming,
decreased exploration of environment...”
“Deficits in social interaction, excessive grooming,
decreased exploration of environment...”
“MOA” – “increased glutamatergic drive, which is
consistent with a loss of retrograde feedback
inhibition.”
“MOA” – “increased glutamatergic drive, which is
consistent with a loss of retrograde feedback
inhibition.”
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
34. B
“Endocannabinoid deficiency syndrome” – 2001
•“In certain conditions, whether congenital or
acquired, endocannabinoid tone becomes deficient and
productive of pathophysiological syndromes.”
•many brain disorders are based on deficient
neurotransmitters.
“Endocannabinoid deficiency syndrome” – 2001
•“In certain conditions, whether congenital or
acquired, endocannabinoid tone becomes deficient and
productive of pathophysiological syndromes.”
•many brain disorders are based on deficient
neurotransmitters.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
35. 19 results August 10, 201819 results August 10, 2018
• Stimulating ECS:
• Reduction in alcohol consumption with +ECS input
• Antihyperalgesic activities of EC in Mouse Model of
neuropathic pain
• Effects in migraine, fibromyalgia, irritable bowel, and
“other treatment-resistant syndromes” (Russo EB, 2016)
• CB2 deficient mice have pro-inflammatory obesity
• Stimulating ECS:
• Reduction in alcohol consumption with +ECS input
• Antihyperalgesic activities of EC in Mouse Model of
neuropathic pain
• Effects in migraine, fibromyalgia, irritable bowel, and
“other treatment-resistant syndromes” (Russo EB, 2016)
• CB2 deficient mice have pro-inflammatory obesity
36. “Ethan B. Russo's paper of December 1, 2003
explored the concept of a clinical endocannabinoid
deficiency (CECD) underlying the pathophysiology of
migraine, fibromyalgia, irritable bowel syndrome and
other functional conditions alleviated by clinical
cannabis.”
“Ethan B. Russo's paper of December 1, 2003
explored the concept of a clinical endocannabinoid
deficiency (CECD) underlying the pathophysiology of
migraine, fibromyalgia, irritable bowel syndrome and
other functional conditions alleviated by clinical
cannabis.”“Subsequent research has confirmed that underlying
endocannabinoid deficiencies indeed play a role in
migraine, fibromyalgia, irritable bowel syndrome and
a growing list of other medical conditions.”
“Subsequent research has confirmed that underlying
endocannabinoid deficiencies indeed play a role in
migraine, fibromyalgia, irritable bowel syndrome and
a growing list of other medical conditions.”
Smith SC, Wagner MS. Neuro Endocrinol Letter. 2014;35(3):198-201.
37. Bluett RJ. Central anandamide deficiency predicts stress-induced
anxiety: behavioral reversal through endocannabinoid
augmentation. Transl Psych 2014 Jul 8;4:e 408
• Pharmacological augmentation of central endogenous
cannabinoid (eCB) signaling may be an effective
therapeutic strategy to mitigate the adverse behavioral
and physiological consequences of stress.
• These studies provide further support that eCB-
augmentation is a viable pharmacological strategy
for the treatment of stress-related neuropsychiatric
disorders.
• Pharmacological augmentation of central endogenous
cannabinoid (eCB) signaling may be an effective
therapeutic strategy to mitigate the adverse behavioral
and physiological consequences of stress.
• These studies provide further support that eCB-
augmentation is a viable pharmacological strategy
for the treatment of stress-related neuropsychiatric
disorders.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
38. statistically significant differences in cerebrospinal fluid anandamide
levels have been documented in migraineurs, and advanced imaging
studies have demonstrated ECS hypofunction in post-traumatic stress
disorder. Additional studies have provided a firmer foundation for the
theory, while clinical data have also produced evidence for decreased
pain, improved sleep, and other benefits to cannabinoid treatment and
adjunctive lifestyle approaches affecting the ECS.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
39. Inflammation and CBD
• CBD tested on mice that had a
version of RA
– CBD reduced mouse inflammation
by 50% at correct dosage
– Malfait AM et al. The nonpsychoactive cannabis
constituent cannabidiol is an oral anti-arthritic
therapeutic in murine collagen- induced arthritis.
PNAS vol 97 no 17, 9561-9566
• one dosage of CBD immediately
following a heart attack can reduce
infarct size by c. 66%
– Durst R et al. Am J Physiol Heart Circ
Physiol.2007Dec;293(6): H3602-7.This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
40. B
These data suggest that anandamide blocks
human breast cancer cell proliferation
through CB1-like receptor-mediated
inhibition of endogenous prolactin action
at the level of prolactin receptor.
These data suggest that anandamide blocks
human breast cancer cell proliferation
through CB1-like receptor-mediated
inhibition of endogenous prolactin action
at the level of prolactin receptor.This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
41. B
Both endocannabinoids exhibited
neuroprotective activity at LOWER dose,
but were neurotoxic at higher dose.
Both endocannabinoids exhibited
neuroprotective activity at LOWER dose,
but were neurotoxic at higher dose.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
42. B
CONCLUSIONS. This data shows that acute
administration of CBD reduces resting BP and the
BP increase to stress in humans, associated with
increased HR.
CONCLUSIONS. This data shows that acute
administration of CBD reduces resting BP and the
BP increase to stress in humans, associated with
increased HR.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
43. What does the literature say about…
• Pain
• Sleep
• Anxiety
• Seizures
• IBS
• ADHD
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
44. “Endocannabinoids, a group of less well--known endogenous bioactive lipids ... [are]
able to influence both inflammation and pain.”
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
45. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
46. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
47. • are under circadian control
• promote non-rapid eye movement sleep
• promote REM by interacting with melanin-
concentrating hormone neurons
• restores sleep in a model of insomnia in rats
Endocannabinoids sleep – 107 citations 8/22/2018
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
48. • cannabidiol (CBD), while representing a less
specific pharmacological approach, may be another
way to modulate eCBs and interacting
neurotransmitter systems to alleviate anxiety.
Endocannabinoids anxiety– 324 citations
8/22/2018
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
49. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
50. CONCLUSIONS:
Our findings demonstrate that the deletion of
Dagla [dacylgerol lipase alpha (DAGLalpha)]
adversely affects the emotional state of animals
and results in enhanced anxiety, stress, and fear
responses.
CONCLUSIONS:
Our findings demonstrate that the deletion of
Dagla [dacylgerol lipase alpha (DAGLalpha)]
adversely affects the emotional state of animals
and results in enhanced anxiety, stress, and fear
responses.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
51. Seizures
“These data suggest the need for developing novel
treatments using compounds that selectively target
individual elements of the endocannabinoid signaling
system.
“These data suggest the need for developing novel
treatments using compounds that selectively target
individual elements of the endocannabinoid signaling
system.
93 citations on “endocannabinoid system epilepsy” – 8/22/2018lsdkfj
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
52. Endocannabinoid system and IBS
Hasenoehri C et al. The gastrointestinal tract – a central organ of cannabinoid signaling in
health and disease. Neurogastroenterol. Motil. 2016 Dec; 28(12):1765-1780.
“Cannabinoid receptors and their
endogenous ligands, the endocannabinoids,
participate in the regulation of GI motility,
secretion, and the maintenance of the
epithelial barrier integrity.”
“Cannabinoid receptors and their
endogenous ligands, the endocannabinoids,
participate in the regulation of GI motility,
secretion, and the maintenance of the
epithelial barrier integrity.”
Endocannabinoid system irritable bowel syndrome
– 238citations - 8/22/2018
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
53. ADHD & the Endocannabinoid System
• 18 citations in literature – 8/22/2018
– “adults with ADHD may represent a subgroup of
individuals who experience a reduction of
symptoms and no cognitive impairments
following cannabinoid use.”
• Cooper RE et al. Eur Neuropsychopharmacol. 2017
Aug; 27(8):795-808
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
54. • 30 adults with ADHD, placebo controlled study
• Sativex Oromucosal spray was used.
• “Adults with ADHD may represent a sub-group of
individuals who experience a reduction of symptoms
and no cognitive impairments following cannabinoid
use.”
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
55. Bioavailability problems of
commercial products
• Commercial hemp oil
– Not THC free.
– Only 6% of what is ingested gets absorbed.
– 90% is wasted.
• micellized hemp oil* = 85% bioavailability
– Onset of action drops from 1-2 hours down to 5 – 15 min.
• ultra micellized hemp oil* = 94% bioavailability
* Note = generic, non-branded products are cited
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
56. Full Spectrum Hemp Oil
NOT just CBD…
• Cannabinoids
• Terpenes
• Flavonoids
• Fatty Acids
• Vitamins
• Minerals
7
57. • Inhibits cancer cell
growth
• Neuroprotective
• Grows bone
• Reduces
seizures/convulsions
• Reduces
inflammation
• Relieves pain/anxiety
• Tranquilizing
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
58. Micellation
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
59. Study of one hemp oil at Mayo Clinic
• N = 20
• Up to 94% absorption of cannabinoids in 12 hours
– 10.9 mg of CBD in the hemp oil
– - 8.3 mg back in the blood
• Blood drawn every 15 minutes and then hourly out to 11 hours
• 50% of this hemp oil was in the body in about 20
minutes.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
60. This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
61. • 2000 inappropriate online health
claims; 1000 still online
• www.truthinadvertising.org , 2017
• 158 direct selling companies
• 62 sell nutritional supplements
• 60/62 (97%) have made health claims
that...
• “their products can diagnose, treat,
cure, prevent, or alleviate the
symptoms of and/or reduce the risk of
developing a multitude of diseases.”
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
62. Obligatory disclaimer. These
statements have not been evaluated by
the Food and Drug Administration. This
product is not intended to diagnose,
treat, cure or prevent any disease.
https://extranet.securefreedom.com/Zilis/Personal/Resources/ZilisComplianceTraining.pd
f
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
63. Personal collection
Louis B. Cady,
M.D.
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
64. Thank you for coming!
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
65. Contact information:
Louis B. Cady, M.D.
www.cadywellness.com
Office: 812-429-0772
E-mail: lcady@cadywellness.com
For appointments: info@cadywellness.com
4727 Rosebud Lane – Suite F
Interstate Office Park
Newburgh, IN 47630 (USA)
This slide deck is not approved by the FDA. No Zilis product can be represented to treat, prevent, mitigate, or cure any disease. They
are used ONLY for the structure and support of the body – specifically, the endocannabinoid system.
Editor's Notes
cfL The Rivers of Lethe and Mnemosyne Converge: Propofol and Memory Consolidation
Hugh C. Hemmings, M.D., Ph.D.; Ken Mackie, M.D.
Author Affiliations & Notes
Anesthesiology 6 2011, Vol.114, 1277-1279. doi:10.1097/ALN.0b013e31821c647d
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1933489