Mari A. - Zennaro D. Allergologia nel III° Millennio: cosa è cambiato e cosa ...Gianfranco Tammaro
DOTT. MARI ADRIANO - DOTT.SSA ZENNARO DANILA (Sessione del 01/10/2015) - Convegno "Lunch Meeting al Pasteur: What's New In..." - dal 01/10/2015 al 10/12/2015 - Studio Pasteur - Viale Pasteur, 66 - Roma
Sito: www.asmad.net
Canale Youtube: https://www.youtube.com/channel/UCIggSJlnC77uDHuX5TUoFHg
Perchè le allergie sono in continuo aumento? L’allergia è una malattia ereditaria? Che cos’è un’allergia? Come possiamo contenere questa “epidemia” in continua crescita? Quali sono le cause di questa crescita allarmante? Quali sono le differenze tra allergia e intolleranza? Le risposte a queste e a molte altre domande ancora in questo approfondito articolo.
This document summarizes a presentation on molecular diagnostics in food allergy. It discusses the limitations of current diagnostic tests in establishing food allergy and differentiating sensitization from clinical allergy. Component resolved diagnostics is presented as a method to improve diagnosis by identifying specific allergenic proteins and predicting severity. Examples of molecular diagnostics for several common foods like peanuts, kiwi, tomatoes and hazelnuts are provided. The conclusions emphasize that molecular diagnostics can help risk stratification but results vary geographically and more research is still needed to fully characterize allergens for many foods.
Mari A. - Zennaro D. Allergologia nel III° Millennio: cosa è cambiato e cosa ...Gianfranco Tammaro
DOTT. MARI ADRIANO - DOTT.SSA ZENNARO DANILA (Sessione del 01/10/2015) - Convegno "Lunch Meeting al Pasteur: What's New In..." - dal 01/10/2015 al 10/12/2015 - Studio Pasteur - Viale Pasteur, 66 - Roma
Sito: www.asmad.net
Canale Youtube: https://www.youtube.com/channel/UCIggSJlnC77uDHuX5TUoFHg
Perchè le allergie sono in continuo aumento? L’allergia è una malattia ereditaria? Che cos’è un’allergia? Come possiamo contenere questa “epidemia” in continua crescita? Quali sono le cause di questa crescita allarmante? Quali sono le differenze tra allergia e intolleranza? Le risposte a queste e a molte altre domande ancora in questo approfondito articolo.
This document summarizes a presentation on molecular diagnostics in food allergy. It discusses the limitations of current diagnostic tests in establishing food allergy and differentiating sensitization from clinical allergy. Component resolved diagnostics is presented as a method to improve diagnosis by identifying specific allergenic proteins and predicting severity. Examples of molecular diagnostics for several common foods like peanuts, kiwi, tomatoes and hazelnuts are provided. The conclusions emphasize that molecular diagnostics can help risk stratification but results vary geographically and more research is still needed to fully characterize allergens for many foods.
Terapia dello Shock Anafilattico - AdrenalinaFilippo Fassio
The document discusses guidelines for the assessment and management of anaphylaxis. It emphasizes the importance of promptly diagnosing anaphylaxis and administering epinephrine as the first-line treatment. While epinephrine is essential, the evidence for managing anaphylaxis is limited compared to other conditions. The guidelines focus on basic initial treatment that can be provided even in low-resource settings. Oxygen supplementation, intravenous fluids, and monitoring vitals are also recommended components of anaphylaxis management.
This document summarizes a study investigating isolated natural killer (NK) cell deficiencies in children with herpetic encephalitis. The study found that NK cell deficiencies, either numeric or functional, were present in all patients affected by severe herpetic infection with encephalitis. One patient also had reduced T cells expressing NK receptors. Testing found three patients had absolute NK deficiency while two had a functional NK deficiency due to a CD16 polymorphism. The conclusions were that NK deficiencies play a role in increased incidence and severity of viral infections, and identifying high-risk patients could help prevent exposures and prompt early antiviral treatment.
This document summarizes the history and evolution of allergy testing from 1880 to present day. It discusses early methods like provocation testing and the characterization of IgE in the 1960s-1970s. Modern developments introduced recombinant allergens in 1995, allergen microarrays in 2001, and now over 103 molecular allergens can be tested. The document also presents and analyzes three case studies involving pollen, latex, and food allergies. It emphasizes that both traditional testing with extracts and newer molecular testing are still needed due to the complexity of allergies. CRD and molecular allergology are active areas of research that young allergists should learn alongside traditional diagnostics.
1. OMCEO Pistoia, 17 Maggio 2012
Seminario di Allergologia
Filippo Fassio
SOD Immunologia e Terapie Cellulari
AOU Careggi
(Direttore Prof. E. Maggi)
2. «Epidemia allergica»
• Le patologie allergiche hanno alta prevalenza
nella popolazione:
– Rinite: 25-35%
– Asma: 5-15%
– Orticaria acuta: 5-25% (cronica 1%)
• Il trend è in crescita (nei Paesi industrializzati):
– Ricoveri per anafilassi in aumento
del 9% annuo
J Allergy Clin Immunol 2007;120:878-84
10. Urticaria and angioedema are commonly encountered
complaints in the primary care physician’s office.
Although the diagnosis is clear, discovering an etiology
can be challenging, prompting referral most frequently
to an allergist or dermatologist.
11. Acute urticaria (…) can frequently be attributed to
viral infections, medications, or foods.
Attempting to discover the etiology of chronic
urticaria can be perplexing, with as many as 80% of
chronic urticarial cases historically considered
idiopathic.
16. L’orticaria è una condizione comune e facile da riconoscere,
tuttavia la diagnosi eziologica può presentare notevoli
difficoltà.
Le reazioni avverse ad alimenti o farmaci costituiscono
solo una parte delle cause di orticaria acuta.
(molto raramente di orticaria cronica)