This document outlines negative pressure wound therapy (NPWT), also known as vacuum assisted closure (VAC). It discusses the mechanism of action, components, indications, contraindications, application process, advantages, monitoring considerations, potential complications, and conclusion regarding NPWT. NPWT applies sub-atmospheric pressure to a wound through a sealed dressing to promote healing in acute or chronic wounds by removing excess fluid, increasing blood flow, and stimulating the growth of new tissue. It is indicated for various open wounds where closure is not possible, such as pressure ulcers, surgical wounds, diabetic ulcers, and more. Contraindications include wounds with necrotic tissue or exposed anatomy. Monitoring includes pressure levels, drainage