This document summarizes the use of negative pressure wound therapy (NPWT), also known as vacuum-assisted closure (VAC). It discusses how VAC works by applying subatmospheric pressure to open wounds to promote healing. Key points include that VAC helps remove dead tissue, improves blood flow to the wound, and pulls wound edges together. The document reviews appropriate applications of VAC, such as soft tissue trauma and skin grafts, and contraindications like non-debrided wounds. Installation and maintenance of the VAC system is also outlined.