Coenzyme Q10 (CoQ10) is a naturally occurring substance in the body that acts as an antioxidant. It is involved in energy production for cells and protects cells from damage. Research shows CoQ10 may help treat conditions like heart disease and Parkinson's disease by improving heart and immune function. Typical doses range from 100-200mg per day, though higher doses may be needed for certain conditions. CoQ10 supplements are commonly used in pets for heart health. Sources listed numerous studies on CoQ10's benefits for conditions like heart failure and its ability to slow progression of Parkinson's disease.
Food as Medicine: CoQ10. History of CoQ10, Synthesis, functions, bioavailability, effect of age and drugs on tissue concentration, use of CoQ10 on heart failure and hypertension, dosage, side effects, recommended dose, food sources.
Folic acid and vitamin B9, is one of the B vitamins.The recommended daily intake level of folate is 400 micrograms from foods or dietary supplements.Folic acid is used to treat anemia caused by folic acid deficiency.It is also used as a supplement by women during pregnancy to prevent neural tube defects (NTDs) in the baby.
Food as Medicine: CoQ10. History of CoQ10, Synthesis, functions, bioavailability, effect of age and drugs on tissue concentration, use of CoQ10 on heart failure and hypertension, dosage, side effects, recommended dose, food sources.
Folic acid and vitamin B9, is one of the B vitamins.The recommended daily intake level of folate is 400 micrograms from foods or dietary supplements.Folic acid is used to treat anemia caused by folic acid deficiency.It is also used as a supplement by women during pregnancy to prevent neural tube defects (NTDs) in the baby.
Recent updates about Vitamin D (sunshine vitamin) & bone health. Co-testing of vitamin D(25-OH vitamin D) along with PTH is a scientific, holistic approach for diagnosis & monitoring of vitamin D deficiency.
VITAMIN D[ SUNSHINE VITAMIN] MEDICINAL CHEMISTRY BY P. RAVISANKAR, CHEMISTRY ...Dr. Ravi Sankar
VITAMIN D[ SUNSHINE VITAMIN] MEDICINAL CHEMISTRY BY P. RAVISANKAR, CHEMISTRY OF VITAMIN D ,STRUCTURES OF VITAMIN D1,D2,D3,D4,D5, VITMIN D SOURCES,RECOMMENDED DIETARY ALLOWANCE,VITAMIN D DEFICIANCY OCCURS IN ,MECHANISM OF ACTION,VITAMIN D FUNCTIONS,VITAMIN D DEFICIENCY(RICKETS),PHYSIOLOGICALROLE/IMPORTANCE,ADVERSE/TOXIC EFFECTS,USES OF VITAMIN D
BY P.RAVISANKAR, VIGNAN PHARMACY COLLEGE, VADLAMUDI, GUNTUR, A.P, INDIA.
Was recently asked to discuss whether there is evidence to support the use of B vitamins in managing different aches and pains. Here's my talk delivered last 16 Sept 2016 at the 12th Post Graduate Course of the East Avenue Medical Center Department of Internal Medicine.
Metabolisme Vitamin K 150207083423-conversion-gate01Muhammad Luthfan
Materi kiuliah tentang metabolisme Vitamin K.
Perhatian: Slide ini mengandung GAMBAR MAKHLUK BERNYAWA yang hanya untuk keperluan ILMU PENGETAHUAN saja.
Dimohon membaca hadits tentang menggambar makhluk bernyawa dibawah ini:
*If you do not understand please translate the Hadith below in English
من صوَّرَ صورةً في الدُّنيا كلِّفَ يومَ القيامةِ أن ينفخَ فيها الرُّوحَ ، وليسَ بنافخٍ
“barangsiapa yang di dunia pernah menggambar gambar (bernyawa), ia akan dituntut untuk meniupkan ruh pada gambar tersebut di hari kiamat, dan ia tidak akan bisa melakukannya” (HR. Bukhari dan Muslim).
كلُّ مُصوِّرٍ في النَّارِ ، يُجْعَلُ له بكلِّ صورةٍ صوَّرها نفسٌ فتُعذِّبُه في جهنَّمَ
“semua tukang gambar (makhluk bernyawa) di neraka, setiap gambar yang ia buat akan diberikan jiwa dan akan mengadzabnya di neraka Jahannam” (HR. Bukhari dan Muslim).
English:
Caution: This slide contains images of animate beings which are used for scientific purposes only.
Hadith:
Sahih Al Bukhari Chapter 89:
Narrated Muslim:
We were with Masruq at the house of Yasar bin Numair. Masruq saw pictures on his terrace and said, "I heard `Abdullah saying that he heard the Prophet (ﷺ) saying, "The people who will receive the severest punishment from Allah will be the picture makers.'"
Cobalamin (vitamin b12) – Lippincott’s Illustrated Reviews World Wide Web Maryam Fida
Vitamin B12 is synthesized only by microorganisms and it is not present in plants
Animals obtain the vitamin preformed from their natural bacterial flora or by eating foods derived from other animals
Present in appreciable amounts in liver, red meat, fish, eggs , dairy products , and fortified cereals
Required in humans for two essential enzymatic reactions
Remethylation of homocysteine (Hcy) to methionine
Isomerization of methylmalonyl coenzyme A (CoA), which is produced during the degradation of some amino acids (isoleucine, valine, threonine and methionine ) and fatty acids (FAs ) with odd numbers of carbon atoms
DEFICIENCY
When cobalamin is deficient, Fatty Acids accumulate and become incorporated into cell membranes , including those of the central nervous system (CNS) resulting in neurologic symptoms
The physiologic coenzyme forms of cobalamin are 5'- deoxyadenosylcobalamin and methylcobalamin
Folic acid (as N5-methyl THF) is also required in the remethylation of Hcy. Therefore , deficiency of B12 or folate results in elevated Hcy levels.
Recent updates about Vitamin D (sunshine vitamin) & bone health. Co-testing of vitamin D(25-OH vitamin D) along with PTH is a scientific, holistic approach for diagnosis & monitoring of vitamin D deficiency.
VITAMIN D[ SUNSHINE VITAMIN] MEDICINAL CHEMISTRY BY P. RAVISANKAR, CHEMISTRY ...Dr. Ravi Sankar
VITAMIN D[ SUNSHINE VITAMIN] MEDICINAL CHEMISTRY BY P. RAVISANKAR, CHEMISTRY OF VITAMIN D ,STRUCTURES OF VITAMIN D1,D2,D3,D4,D5, VITMIN D SOURCES,RECOMMENDED DIETARY ALLOWANCE,VITAMIN D DEFICIANCY OCCURS IN ,MECHANISM OF ACTION,VITAMIN D FUNCTIONS,VITAMIN D DEFICIENCY(RICKETS),PHYSIOLOGICALROLE/IMPORTANCE,ADVERSE/TOXIC EFFECTS,USES OF VITAMIN D
BY P.RAVISANKAR, VIGNAN PHARMACY COLLEGE, VADLAMUDI, GUNTUR, A.P, INDIA.
Was recently asked to discuss whether there is evidence to support the use of B vitamins in managing different aches and pains. Here's my talk delivered last 16 Sept 2016 at the 12th Post Graduate Course of the East Avenue Medical Center Department of Internal Medicine.
Metabolisme Vitamin K 150207083423-conversion-gate01Muhammad Luthfan
Materi kiuliah tentang metabolisme Vitamin K.
Perhatian: Slide ini mengandung GAMBAR MAKHLUK BERNYAWA yang hanya untuk keperluan ILMU PENGETAHUAN saja.
Dimohon membaca hadits tentang menggambar makhluk bernyawa dibawah ini:
*If you do not understand please translate the Hadith below in English
من صوَّرَ صورةً في الدُّنيا كلِّفَ يومَ القيامةِ أن ينفخَ فيها الرُّوحَ ، وليسَ بنافخٍ
“barangsiapa yang di dunia pernah menggambar gambar (bernyawa), ia akan dituntut untuk meniupkan ruh pada gambar tersebut di hari kiamat, dan ia tidak akan bisa melakukannya” (HR. Bukhari dan Muslim).
كلُّ مُصوِّرٍ في النَّارِ ، يُجْعَلُ له بكلِّ صورةٍ صوَّرها نفسٌ فتُعذِّبُه في جهنَّمَ
“semua tukang gambar (makhluk bernyawa) di neraka, setiap gambar yang ia buat akan diberikan jiwa dan akan mengadzabnya di neraka Jahannam” (HR. Bukhari dan Muslim).
English:
Caution: This slide contains images of animate beings which are used for scientific purposes only.
Hadith:
Sahih Al Bukhari Chapter 89:
Narrated Muslim:
We were with Masruq at the house of Yasar bin Numair. Masruq saw pictures on his terrace and said, "I heard `Abdullah saying that he heard the Prophet (ﷺ) saying, "The people who will receive the severest punishment from Allah will be the picture makers.'"
Cobalamin (vitamin b12) – Lippincott’s Illustrated Reviews World Wide Web Maryam Fida
Vitamin B12 is synthesized only by microorganisms and it is not present in plants
Animals obtain the vitamin preformed from their natural bacterial flora or by eating foods derived from other animals
Present in appreciable amounts in liver, red meat, fish, eggs , dairy products , and fortified cereals
Required in humans for two essential enzymatic reactions
Remethylation of homocysteine (Hcy) to methionine
Isomerization of methylmalonyl coenzyme A (CoA), which is produced during the degradation of some amino acids (isoleucine, valine, threonine and methionine ) and fatty acids (FAs ) with odd numbers of carbon atoms
DEFICIENCY
When cobalamin is deficient, Fatty Acids accumulate and become incorporated into cell membranes , including those of the central nervous system (CNS) resulting in neurologic symptoms
The physiologic coenzyme forms of cobalamin are 5'- deoxyadenosylcobalamin and methylcobalamin
Folic acid (as N5-methyl THF) is also required in the remethylation of Hcy. Therefore , deficiency of B12 or folate results in elevated Hcy levels.
Few years ago my father, who was CVD patient, passed away due to heart attack. He was only 61. Same thing happened with my mom in law. She was just 57. Then recently some distant relatives were affected by CVD/CAD. Many people are aware of this disease but I feel that they just live with it. Some do take precautions to avoid but may be it is not enough. I decided to learn more about this and learn how one can take precautions. This is a vast subject hence the presentation I put together is just a beginning of scratching the surface. Lot of information is available on the right websites and books. I refer to one such book.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
2. This is for personal use only.
● This presentation if for my personal use.
● This does not promote use with out a doctor
care or intent to dispense.
● This is strictly my personal opinion.
● This information is for reference purpose only.
● Not a guide to self treatment or medical
purpose.
3. This is for personal use.
● This does not attempt or to self diagnose in
anyway, shape or form or to do so on this slides
or any other of my slides.
● This information treated here or on any of my
slides is not to substitute for any treatment
that may be subscribed by a doctor.
● I would recommend before you try this, contact
a medical professional.
4. Uses for COQ10
● Coenzyme Q10 is most commonly used for
conditions that affect the heart such as heart
failure, chest pain, and high blood pressure.
● It is also used for preventing migraine
headache, Parkinson's disease, and many
other conditions.
5. Source: Webmd
● What does CoQ10 do for the body?
● Coenzyme Q10 (CoQ10) is a substance similar
to a vitamin. It is found in every cell of the body.
● Your body makes CoQ10, your cells use it to
produce energy your body needs for cell growth
and maintenance.
● It also functions as an antioxidant, which
protects the body from damage caused by
harmful molecules.
6. Uses of COQ10
● COQ10: Helps treat high blood pressure &
heart failure
● COQ10:Enhances immune system function in
people with HIV or AIDS
● COQ10:Improves symptoms of chronic fatigue
syndrome
● COQ10: Reduces high cholesterol levels in the
blood
7. How much COQ10?
● How much CoQ10 should I take a day?
● Studies have used doses of CoQ10 ranging
from 50 milligrams to 1,200 milligrams in adults,
sometimes split into several doses over the
course of a day.
● A typical daily dose is 100 milligrams to 200
milligrams. Follow the instructions on the bottle
or get advice from your doctor or a dietitian.
8. COQ10 for Parkinson's.
● How does CoQ10 help for Parkinson's disease:
● Research on CoQ10 use for specific conditions
and activities shows:
● Parkinson's disease. Early research suggests
that high doses of CoQ10 might be beneficial...
● High doses of the popular supplement
coenzyme Q10 helps slow the progression of
Parkinson's disease in some patients by as
much as half, researchers report.
9. Uses for COQ10
● Enhancing immune system function in people
with HIV or AIDS
● Improving symptoms of chronic fatigue
syndrome
● Reducing high cholesterol levels in the blood
● Assisting in the treatment of cancer or the
protection of organs from toxic chemotherapy
drugs
10. COQ10 Uses
● Treating gum disease
● Treating age-related macular degeneration
(AMD), a condition that causes vision loss in
older adults
● Helping with Alzheimer’s disease
● Increasing sperm count and motility
● Preventing or treating migraine headaches
11. COQ10 can help with ANGINA
● Coenzyme Q10 (CoQ10). For ANGINA:This
powerful antioxidant can benefit heart health by
influencing the mitochondria, the tiny
powerhouses found in heart cells and in cells
throughout the body, which is where energy
metabolism occurs.
● In this way, CoQ10 may help lower the heart’s
oxygen demands by improving its energy
efficiency. It may also help lower blood
pressure. The dose is 60-100 mg a day.
12. COQ10 may also help with
Arrhythmia
● CoQ10 Strengthens Heart Muscle:
● Coenzyme Q10 (CoQ10) is found in human
mitochondria, the energy-generating
powerhouses of the body’s cells.
● CoQ10 has been in the spotlight recently
because cholesterol-lowering statin drags are
believed to deplete CoQ10 levels in muscle
tissue, thus causing the common muscle aches
suffered by many statin users.17
13. Foods containing COQ10
● The following foods contain CoQ10:
● Organ meats: Heart, liver & kidney.
● Some muscle meats: Pork, beef &chicken.
● Fatty fish: Trout, herring, mackerel &sardine.
● Vegetables: Spinach, cauliflower & broccoli.
● Fruit: Oranges and strawberries.
● Legumes: Soybeans, lentils and peanuts.
15. Exactly just what is COQ10?
What is coenzyme Q-10?
● Coenzyme Q-10 (CoQ-10, CoQ10 or
ubiquinone) exists in abundance in every
human and animal body.
● It is an essential component of the
mitochondria, which are the parts of the cell
that produce energy from oxygen.
16. Just what is COQ10?
● It , COQ10 is thus especially important to the
function of organs with a high demand for
oxygen, including the heart and the brain,
resulting in coenzyme Q-10 being studied as a
treatment for heart disease; Parkinson's
disease in humans.
● Because Coenzyme Q-10 has a natural affinity
for oxygen and other oxidizing compounds, it
binds to them and serves also as an
antioxidant.
17. COQ10 for PETS? REALLY?
● Why recommend administration of coenzyme
Q-10 to my pet?
● Coenzyme Q-10: is potentially useful to support
the function of any organ with a very high
energy requirement, including the heart muscle.
● Rresearch has shown a significant correlation
between reduced levels of CoQ-10 & the
incidence of heart disease.
19. COQ10 for people & pets.
● Coenzyme Q-10 thus is a standard inclusion in
many supplements designed to improve heart
function.
● "Coenzyme Q-10 is potentially useful to
support the function of any organ with a very
high energy requirement..."
● As an antioxidant CoQ-10 is used where
oxidizing chemicals are causing significant cell
damage, leading to the formation of cancer
cells and chronic inflammatory changes.
20. COQ10 for PETS
● How much experience is there with the use of
coenzyme Q-10 in pets?
● Coenzyme Q-10 has been used in people &
pets for several years for the treatment of heart
disease.
● Double blinded studies of CoQ-10 show a clear
improvement in heart function in patients with
chronic heart disease.
21. USES for COQ10?
● Recently it has been recommended for treating
cancer and gingivitis, although research
evidence is lacking.
● Improved outcomes have been reported in
patients receiving both CoQ-10 and
chemotherapy for cervical cancer.
22. COQ10 for CAT & DOGS
● What species of animals are being treated
regularly with coenzyme Q-10?
● Dogs and cats are the pets most commonly
prescribed coenzyme Q-10.
23. USES FOR PETS FOR COQ10
● How much research has been conducted on this
supplement?
● Coenzyme Q-10: has shown effectiveness in research
studies conducted on dogs with heart disease and
heart failure.
● Clinical experience suggests its effectiveness for pets
with periodontal disease and as part of a cancer
protocol. Coenzyme Q-10 has been shown to protect
against heart damage caused by certain types of
cancer chemotherapy (such as Adriamycin).
25. COQ10 for pets
● How can my pet benefit from coenzyme Q-10?
● For pets with heart disease, coenzyme Q-10 can help the
heart function as optimally as possible.
● Effects of CoQ-10 alone are probably only mild to
moderate, but research suggests there may be a
synergistic (complementary) interaction between CoQ-10
and other cardiac medications.
● A reduction in heart muscle pathology (abnormality) has
been demonstrated in dogs with heart disease receiving
CoQ-10, and a slowing of the progression of clinical signs
has been observed clinically.
26. COQ10 is wrinkle prevention.
● CoQ10 -It protects skin from UV damage and
even helps repair wrinkles.
● German researchers discovered rubbing
CoQ10 on human skin actually changes cell
metabolism.
● Old skin cells suddenly become energized and
act more like young cells again!
27. COQ10 is great for heart health.
● In the 1980’s, doctors showed that CoQ10 can
reverse the effects of cardiomyopathy – a form
of heart disease that results in a weak heart.
● Patients taking CoQ10 were 2/3 less likely to
die than patients receiving conventional
treatments.
28. COQ10 Reseach
● In one landmark study, researchers gave
CoQ10 to seven congestive heart failure
patients. All seven patients had a 94% chance
of dying within 12 months.
● The results were stunning: 6 out of 7 patients
survived. And get this: The one patient that died
stopped taking the CoQ10 three months into
the trial testing.
29. COQ10 heart health
● Congestive heart failure (CHF) means your
heart can’t pump enough blood to fully
oxygenate your cells.
● This leads to fluid congestion that can cause
your vital organs like your lungs, brain and
kidneys to shut down.
● And low CoQ10 levels are a reliable predictor of
mortality in CHF patients. In other words, the
lower your CoQ10 levels, the higher your risk of
dying.
30. Sources & References: for COQ10
● Sources for COQ10:
● Everyday Health
● WebMD
● Life Extension Magazine
● Rundek T, Naini A, Sacco R, Coates K,
DiMauro S. Atorvastatin decreases the
coenzyme Q10 level in the blood of patients at
risk for cardiovascular disease and stroke. Arch
Neurol. 2004 Jun;61(6):889-92.
●
31. Sources & Reference:
● Fujioka T, Sakamoto Y, Mimura G. Clinical
study of cardiac arrhythmias using a 24-hour
continuous electrocardiographic recorder (5th
report)—antiarrhythmic action of coenzyme
Q10 in diabetics. Tohoku J Exp Med. 1983
Dec;141 Suppl:453-63.
● Rauchova H, Drahota Z, Lenaz G. Function of
coenzyme Q in the cell: some biochemical and
physiological properties. Physiol Res.
1995;44(4):209-16.
32. Sources for COQ10
● Lampertico M, Comis S. Italian multicenter
study on the efficacy and safety of coenzyme
Q10 as adjuvant therapy in heart failure. Clin
Investig. 1993;71(8 Suppl):S129-33.
● Baggio E, Gandini R, Plancher AC, Passeri M,
Carmosino G. Italian multicenter study on the
safety and efficacy of coenzyme Q10 as
adjunctive therapy in heart failure. CoQ10 Dug
Surveillance Investigators. Mol Aspects Med.
1994;15 Suppl:s287-94.
33. COQ10 references & sources
● Langsjoen PH, Langsjoen PH, Folkers K.
Isolated diastolic dysfunction of the
myocardium and its response to CoQ10
treatment. Clin Investig. 1993;71(8
Suppl):S140-4.
● Langsjoen P, Langsjoen P, Willis R, Folkers K.
Treatment of essential hypertension with
coenzyme Q10. Mol Aspects Med. 1994;15
Suppl:S265-72.
● Singh RB, Wander GS, Rastogi A, et al. R
34. Sources & References for COQ10
● Coenzyme Q-10-By Steve Marsden, DVM ND
MSOM LAc DiplCH AHG, Shawn Messonnier,
DVM and Cheryl Yuill, DVM, MSc, CVH
Alternative Therapies, Treatment
● WEBMD
● Nature's Prescription: Foods, Vitamins, and
Supplements That Prevent Disease Paperback
– March 1, 1998,by Publisher:Frank W.
Cawood and Associates (Editor)
35. Sources
● Nature's Medicines: From Asthma to Weight
Gain, from Colds to Heart Disease- The Most
Powerful All-Natural Cures Hardcover – August
27, 1999 ● by Gale Maleskey
(Author)Publisher: Rodale Books
● Greenmedinfo LLC,Bonita Springs, FL 34134
36. Sources: on COQ10
● The Healing Nutrient Most Doctors Won’t Prescribe-
January 18, 2012 by Jason Kennedy Discovery Health
Publishing, Inc
● Inui, M., et al, “Mechanisms of inhibitory effects of CoQ10
on UVB-induced wrinkle formation in vitro and in vivo,”
Biofactors. 2008; 32(1-4): 237-243.
● Prahl, S., et al, “Aging skin is functionally anaerobic:
importance of coenzyme Q10 for anti aging skin care,”
Biofactors. 2008; 32(1-4): 245-255.
37. THE END OF COQ10
● If you want to PREVENT heart disease, or if
you’re looking to live a longer, healthier life, you
may need more than the standard 50 mg that’s
usually recommended.
● The recommendation of taking 50 mg likely
came out of the original comparison to the old
form of CoQ10.