Atomic force microscopy (AFM) is a type of high-resolution scanning probe microscope used to image surfaces at the nanoscale. It uses a sharp tip that is attached to a flexible cantilever to measure deflection at a scale of fractions of a nanometer. As the tip is brought near or into contact with a sample surface, forces between the tip and sample lead to deflection of the cantilever that is measured using a laser spot and photodetector. This allows creation of 3D topographic images with high resolution without the need for a vacuum or conductive samples.
General Medicine Interest Group
千葉大学医学部医の学生が主体となり、身体診察スキルとトレーニングする学部公認のサークルです。全8回のセッションを半期で行います。興味のある方は、ご一報ください。
連絡先:千葉大学医学部附属病院 総合診療科 鋪野紀好
メール:kshikino@gmail.com
This document discusses the working principles of a scanning electron microscope (SEM) and its use for fiber characterization. It begins with an introduction to SEMs and their components. Key points made include that SEMs use electron beams rather than light to image samples and can achieve higher resolution than light microscopes. The document then covers SEM signals, image formation, resolution factors, sample preparation, and applications for characterizing fibers like wool, cotton and polyester. Limitations discussed include the sample size and need for vacuum and conductive coating. Overall, the document provides a high-level overview of SEM operation and its advantages for examining textile fiber structure and morphology.
Atomic force microscopy (AFM) is a type of high-resolution scanning probe microscope used to image surfaces at the nanoscale. It uses a sharp tip that is attached to a flexible cantilever to measure deflection at a scale of fractions of a nanometer. As the tip is brought near or into contact with a sample surface, forces between the tip and sample lead to deflection of the cantilever that is measured using a laser spot and photodetector. This allows creation of 3D topographic images with high resolution without the need for a vacuum or conductive samples.
General Medicine Interest Group
千葉大学医学部医の学生が主体となり、身体診察スキルとトレーニングする学部公認のサークルです。全8回のセッションを半期で行います。興味のある方は、ご一報ください。
連絡先:千葉大学医学部附属病院 総合診療科 鋪野紀好
メール:kshikino@gmail.com
This document discusses the working principles of a scanning electron microscope (SEM) and its use for fiber characterization. It begins with an introduction to SEMs and their components. Key points made include that SEMs use electron beams rather than light to image samples and can achieve higher resolution than light microscopes. The document then covers SEM signals, image formation, resolution factors, sample preparation, and applications for characterizing fibers like wool, cotton and polyester. Limitations discussed include the sample size and need for vacuum and conductive coating. Overall, the document provides a high-level overview of SEM operation and its advantages for examining textile fiber structure and morphology.
7. 感染症検査
• インフルエンザ迅速検査:A+
• 痰グラム染色:グラム陽性球菌多数で,貪食像あり
• 高感度MRSA検査(鼻腔):陽性
• 痰培養:MRSA & B群Streptococcus
• 血液培養:MRSA
7枚目/11枚
MRSAの抗菌薬感受性(βラクタムと抗MRSA薬以外)
抗菌薬 MIC 感受性判定
GM <1 S
CLDM <0.5 R
EM >4 R
MINO <2 S
ST <1 S
10. 考察2:インフルエンザとMRSAの共感染
• インフルエンザウィルスとブドウ球菌には,たがいに増殖・感染を促進しあう協力関係がある
と言われている
Tashiro M, et al. Role of Staphylococcus protease in the influenza pneumonia. Nature 325: 536-37, 1987.
• 2009年のパンデミックの際に,オーストラリアの2つの病院に入院したA型インフルエンザ
(H1N1)患者252名中,MRSA感染を合併していた患者は5名であった
RJ Murray, et al. Community acquired pneumonia due to pandemic A (H1N1) 2009 influenza virus and MRSA co-infection. Plos one
5(1): e8785, 2010.
• 本邦においては現時点でこのような報告はなく,頻度はより低いと考えられるが,今後増える
ことが予想される
• マウスの実験モデル において,このような共感染が起こった場合は,VCMよりもLZDのほうが
有効であることが示唆されている
Bhan U, et al. Linezolid has unique immunomodulatory effects in post-influenza community acquired MRSA pneumonia. Plos one
10(1): e0114574, 2015.
10枚目/11枚